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Dietary supplement

Rhodiola Rosea 1000 mg Ingredients & Drug Interactions

by Bronson

Rhodiola Rosea 1000 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Rhodiola Rosea 1000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Rhodiola Rosea 1000 mg is a dietary supplement by Bronson with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, stress and coping (adaptogen), mental performance and focus.Based on those ingredients, 1,271 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Rhodiola rosea root powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Rhodiola Rosea 1000 mg by Bronson

Ask about any prescription or over-the-counter medication and we check it for interactions with Rhodiola Rosea 1000 mg by Bronson — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Rhodiola Rosea 1000 mg by Bronson

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: rhodiola rosea root powder at 1,000 mg per capsule. Rhodiola is an herb traditionally used to support energy, mood, and stress resilience.

The capsule itself is made from modified cellulose, with microcrystalline cellulose, magnesium stearate, and silicon dioxide as inactive ingredients to hold everything together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Rhodiola's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Supports healthy brain function and energy.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Depression, Fatigue, Generalized anxiety disorder (GAD), Stress — and 3 related terms.
  • The closest evidence on file: Rhodiola is rated "Insufficient Reliable Evidence To Rate" for Generalized anxiety disorder (GAD) (Natural Medicines).
  • Also on file: Rhodiola is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Chronic fatigue syndrome (CFS), Depression, Fatigue, and more.

The effectiveness data we hold for rhodiola rosea does not establish reliable evidence for any of the conditions listed — altitude sickness, generalized anxiety disorder, heart arrhythmias, athletic performance, and bladder cancer all show insufficient reliable evidence to rate. That doesn't mean rhodiola doesn't work for these purposes, only that the scientific evidence available to us isn't strong enough to make a confident claim either way.

The evidence, ingredient by ingredient Rhodiola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Rhodiola is generally well tolerated for short-term use, though long-term safety hasn't been well studied. The most common side effects are dizziness and changes in saliva production — either a dry mouth or, less often, excessive saliva.

During pregnancy and breastfeeding, there isn't enough safety data, so the evidence advises against using it. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this supplement.

Side effects, ingredient by ingredient Rhodiola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Rhodiola.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 1,272 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you're on blood pressure medications (antihypertensives) or losartan specifically — rhodiola may lower your blood pressure further. Also confirm if you take blood sugar medications (antidiabetes drugs) or immunosuppressants, since rhodiola could interfere with how well they work.

Finally, ask about any drug that gets broken down by your liver's CYP2C9, P-glycoprotein, CYP1A2, or CYP3A4 pathways — rhodiola may raise its level in your system.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Rhodiola Rosea may appeal to someone looking for an herb to support energy or stress response, but it interacts with a broad range of medications — especially blood pressure drugs, blood sugar medications, and certain immunosuppressants. If you take any prescription drugs, check them against the tool on this page and discuss it with your own doctor or pharmacist before you start.

It's not for use during pregnancy or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Rhodiola Rosea 1000 mg, straight from the product label.

Brand Bronson
Barcode (UPC) X002F0OTHT
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2020
DSLD ID 233126
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Rhodiola Rosea 1000 mg by Bronson, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
X002F0OTHT
IngredientAmount% DV
Rhodiola rosea root powder1000 mg--

Other ingredients: modified Cellulose capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Bronson Nutrition since 1960

120 Count

365 day 100% money back guaranteed Nutrition Questions or Comments? [email protected] Call 1-800-235-3200 Mon. - Fri. 7 AM - 6 PM MST Sat. 8 AM - 4:30 PM MST New

Formulation

Adaptogenic herb Supports healthy brain function and energy Stress and mood support

Non-GMO Gluten-free Soy-free

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement for adults, take 1 capsule daily, preferably with a meal or as directed by a healthcare professional.

Precautions

Warning: Consult a healthcare professional before taking this product if you are pregnant or nursing.

Do not use if seal under cap is broken or missing.

Keep out of reach of children.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Lab Tested Made from High Quality Ingredients GMP Good Manufacturing Practice

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Rhodiola Rosea 1000 mg by Bronson label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Rhodiola Rosea 1000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Rhodiola Rosea 1000 mg by Bronson

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Rhodiola rosea root powder

Interacts with
1,271 drugs
1000 mg per serving

Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue...

Rhodiola rosea root powder monograph & interactions

Other (inactive) ingredients: Modified Cellulose capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Rhodiola Rosea 1000 mg by Bronson Drug Interactions

Want to check YOUR meds against Rhodiola Rosea 1000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,271Drugs
624 Moderate 647 Minor

Ingredients driving the most interactions

Rhodiola rosea root powder 1,271

Individual Drug Interactions

The ingredients in Rhodiola Rosea 1000 mg interact with 1,271 drugs. Click any drug to see the details.

1 of the 1 ingredient in Rhodiola Rosea 1000 mg interact with drugs. Each result below shows which ingredient is responsible. Rhodiola rosea root powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Rhodiola Rosea 1000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Rhodiola rosea root powder10 drug types · 1,271 drugs

Antidiabetes Drugs

Theoretically, taking rhodiola with antidiabetes drugs might increase the risk of hypoglycemia.
In vitro and animal research shows that rhodiola extract can decrease blood glucose due to alpha-glucosidase activity.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking rhodiola with antihypertensive drugs might increase the risk of hypotension.
In vitro and animal research shows that rhodiola extract inhibits angiotensin-converting enzyme (ACE) and might lower blood pressure.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that rhodiola inhibits CYP2C9. This effect is highly variable and appears to be dependent on the rhodiola product studied. Also, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, rhodiola use might interfere with immunosuppressive therapy.
In vitro and animal research show that rhodiola has immunostimulatory effects.

Likelihood Possible Evidence D
Losartan (Cozaar)

Rhodiola might increase the levels and adverse effects of losartan.
A clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days reduces the metabolism of losartan, a CYP2C9 substrate, by 21% after 4 hours.

Likelihood Probable Evidence B
P-Glycoprotein Substrates

Theoretically, rhodiola might increase levels of P-glycoprotein substrates.
In vitro research shows that rhodiola inhibits P-glycoprotein. Theoretically, using rhodiola with P-glycoprotein substrates might increase drug levels and potentially increase the risk of adverse effects.

Likelihood Possible Evidence D
Antidepressant Drugs

Theoretically, rhodiola might increase the risk of adverse effects when taken with antidepressants.
A review of adverse event reports in Poland identified cases of tachyarrhythmias, myalgia, arthralgia, gum pain, restless leg syndrome, swallowing disorders, and changes in consciousness when rhodiola was taken in combination with paroxetine, escitalopram, fluoxetine, sertraline, trazodone, and/or duloxetine.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, rhodiola might increase the risk of adverse effects when taken with CNS depressants.
A review of adverse event reports in Poland identified cases of excessive sedation, myoclonus, hypotension, and hallucinations when rhodiola was taken with haloperidol, diazepam, or alprazolam.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that rhodiola inhibits CYP1A2. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of caffeine, a CYP1A2 substrate.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, rhodiola might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that rhodiola inhibits CYP3A4. This effect is highly variable and appears to be dependent on the rhodiola product studied. However, a clinical study in healthy young males found that taking rhodiola extract 290 mg daily for 14 days does not inhibit the metabolism of midazolam, a CYP3A4 substrate.

Likelihood Possible Evidence B
Rhodiola rosea root powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Rhodiola Rosea 1000 mg, from the product label.

Bronson

Name
Bronson Laboratories
Street Address
70 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
1-800-235-3200
Web Address
BronsonVitamins.com
Pharmacist Counseling Corner

Rhodiola Rosea 1000 mg by Bronson: Common Questions

Does Rhodiola Rosea 1000 mg by Bronson interact with any medications?
Yes. Based on its ingredients, Rhodiola Rosea 1000 mg has a known interaction with 1,271 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Rhodiola Rosea 1000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is rhodiola safe to take while I'm pregnant or breastfeeding?
No. There isn't enough safety data on rhodiola in pregnancy or while breastfeeding, so the evidence advises against it. Talk with your doctor or pharmacist about whether it's right for you in these situations.
What side effects might I notice if I take this?
The most common ones are dizziness and changes in how much saliva your mouth produces — either dry mouth or, occasionally, too much. Most people tolerate it well, especially for short-term use.
Does rhodiola actually work for energy or stress?
We don't hold reliable evidence to confirm it works for those purposes or for any of the other conditions commonly associated with it. That said, absence of strong evidence doesn't mean it doesn't help some people — just that we can't make a confident claim based on the data we have.
Why does this product interact with so many medications?
Rhodiola inhibits several enzymes in your liver that break down drugs. That means it can slow how your body clears certain medications, raising their levels in your bloodstream — which is why the interactions are so broad.
Is rhodiola safe for long-term use?
It's generally well tolerated for short-term use, but long-term safety hasn't been well studied, so we don't have strong data on taking it for months or years. Talk with your pharmacist or doctor about how long you plan to take it.
Can I take this with my blood pressure medication?
Not without checking first. Rhodiola may lower blood pressure on its own, so combining it with blood pressure drugs could increase the risk of your pressure dropping too far. Ask your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Rhodiola Rosea 1000 mg label
Go deeper

The Full Monographs Behind Rhodiola Rosea 1000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Rhodiola

Interacts with 1,271 drugs

Rhodiola is an herb traditionally used to fight fatigue and help the body cope with stress. Some small studies suggest it may modestly reduce fatigue and improve mood, but the evidence is li...

Read the full Rhodiola monograph →
Sources

Sources & How We Checked

Rhodiola Rosea 1000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Rhodiola 13 references
  1. Kim SH, Hyun SH, Choung SY. Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice. Biofactors 2006;26:209-19.
  2. Kwon YI, Jang HD, Shetty K. Evaluation of Rhodiola crenulata and Rhodiola rosea for management of type II diabetes and hypertension. Asia Pac J Clin Nutr 2006;15:425-32.
  3. Bystritsky A, Kerwin L, Feusner JD. A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD). J Altern Complement Med 2008;14:175-80.
  4. Shevtsov VA, Zholus BI, Shervarly VI, et al. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine 2003;10:95-105. PubMed
  5. Apostolidis E, Kwon YI, Shetty K. Potential of cranberry-based herbal synergies for diabetes and hypertension management. Asia Pac J Clin Nutr 2006;15:433-41.
  6. Hellum BH, Tosse A, Hoybakk K, et al. Potent in vitro inhibition of CYP3A4 and P-glycoprotein by Rhodiola rosea. Planta Med 2010;76:331-8.
  7. Skopriska-Rozewska E, Wojcik R, Siwicki AK, et al. The effect of Rhodiola quadrifida extracts on cellular immunity in mice and rats. Pol J Vet Sci 2008;11:105-11.
  8. Mishra KP, Chanda S, Shukla K, Ganju L. Adjuvant effect of aqueous extract of Rhodiola imbricate rhizome on the immune responses to tetanus toxoid and ovalbumin in rats. Immunopharmacol Immunotoxicol 2010;32:141-6.
  9. Li HX, Sze SC, Tong Y, Ng TB. Production of Th1- and Th2-dependent cytokines induced by the Chinese medicine herb, Rhodiola algida, on human peripheral blood monocytes. J Ethnopharmacol 2009;123:257-66. PubMed
  10. Mishra KP, Ganju L, Chanda S, et al. Aqueous extract of Rhodiola imbricate rhizome stimulates Toll-like receptor 4, granzyme-B and Th1 cytokines in vitro. Immunobiology 2009;214:27-31.
  11. Thu OK, Nilsen OG, Hellum B. In vitro inhibition of cytochrome P-450 activities and quantification of constituents in a selection of commercial Rhodiola rosea products. Pharm Bio. 2016 Dec;54(12):3249-3256.
  12. Thu OK, Spigset O, Nilsen OG, Hellum B. Effect of commercial Rhodiola rosea on CYP enzyme activity in humans. Eur J Clin Pharmacol. 2016 Mar;72(3):295-300. PubMed
  13. Woron J, Siwek M. Unwanted effects of psychotropic drug interactions with medicinal products and diet supplements containing plant extracts. Psychiatr Pol 2018;52(6):983-96. PubMed

See these in context on the Rhodiola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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