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Dietary supplement

Royal Maca for Men Vegetarian Capsules Ingredients & Drug Interactions

by Whole World Botanicals

Royal Maca for Men Vegetarian Capsules label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Royal Maca for Men Vegetarian Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Royal Maca for Men Vegetarian Capsules is a dietary supplement by Whole World Botanicals with 4 active ingredients. Its ingredients are commonly taken for morning sickness in pregnancy, premenstrual syndrome (pms), preventing or treating b6 deficiency.Based on those ingredients, 561 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Selenium, Vitamin B6, Zinc Glycinate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Royal Maca for Men Vegetarian Capsules by Whole World Botanicals

Ask about any prescription or over-the-counter medication and we check it for interactions with Royal Maca for Men Vegetarian Capsules by Whole World Botanicals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Royal Maca for Men Vegetarian Capsules by Whole World Botanicals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains four active ingredients. Vitamin B6 (pyridoxine) is a B vitamin involved in nerve and blood health.

Selenium is a mineral that supports antioxidant defenses in your cells. Zinc Glycinate is a form of zinc, a mineral essential for immune function and wound healing.

Royal Maca is a root extract traditionally used as a supplement, though evidence for its specific effects is limited. The capsules also contain cellulose and purified water as inactive ingredients.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Men's sexual function and vitality.
  • We looked for evidence on: Age-related testosterone deficiency, Antidepressant-induced sexual dysfunction, Sexual performance, Erectile function, Libido and desire.
  • The closest evidence on file: Zinc is rated "Possibly Ineffective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction, Age-related testosterone deficiency.

Evidence is strongest for Vitamin B6 — it's effective for sideroblastic anemia and B6 deficiency, likely effective for high homocysteine levels, and possibly effective for pregnancy-related nausea. Selenium is likely effective for selenium deficiency and possibly effective for pre-eclampsia and autoimmune thyroiditis, though the data shows it may be ineffective for high cholesterol.

Zinc is effective for zinc deficiency and Wilson disease, and possibly effective for acne and age-related macular degeneration. For Royal Maca itself, the evidence we hold is insufficient to rate its effectiveness for any of the conditions listed — amenorrhea, chronic anemia, sexual dysfunction, athletic performance, or bone health.

It's marketed as a supplement, but clinical evidence for its specific benefits is not established in our data.

The evidence, ingredient by ingredient Vitamin B6 Selenium Zinc Maca

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

At normal doses, Vitamin B6 is well tolerated, though high doses taken long-term can damage nerves (sensory neuropathy). Selenium is safe within the daily upper limit of 400 mcg, but excess can cause hair loss, nail problems, and nausea; very high intakes have caused serious organ damage.

Zinc is well tolerated below 40 mg daily, though doses above that carry a theoretical risk of copper deficiency over time. Common side effects include nausea, abdominal cramps, and metallic taste.

Royal Maca is generally well tolerated as a food, though uncooked fresh maca may cause stomach pain. Long-term safety as a supplement has not been studied.

No pregnancy safety data is on file for any of these ingredients; avoid Royal Maca in pregnancy and lactation due to insufficient safety data. For the vitamins and minerals, discuss pregnancy use with your doctor or pharmacist — they may be used at recommended levels under guidance, but high doses are not advised.

Side effects, ingredient by ingredient Vitamin B6 Selenium Zinc Maca

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Vitamin B6, Zinc, Selenium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; Parkinson's medications.
  • For scale: 561 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take blood pressure drugs, blood thinners (anticoagulants or antiplatelet agents), antibiotics (quinolones, tetracyclines, or cephalexin), penicillamine, ritonavir, HIV integrase inhibitors, immunosuppressants, barbiturates, warfarin, oral contraceptives, or niacin. These are the drug types with documented interactions.

If none of these apply to you, no interactions are documented in our data for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines three micronutrients with established roles in health (B6, selenium, zinc) plus Royal Maca, which lacks strong clinical evidence. If you take blood pressure medications, blood thinners, antibiotics, or HIV drugs, you'll want to check your specific medications with the tool below before starting.

Anyone pregnant, breastfeeding, or taking high-dose supplements should talk with their pharmacist first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Royal Maca for Men Vegetarian Capsules, straight from the product label.

Brand Whole World Botanicals
Barcode (UPC) 691195001059
Net contents 180 Veg Cap(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 314703
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Male (18-50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Royal Maca for Men Vegetarian Capsules by Whole World Botanicals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
8 Capsule(s)
Servings per container
90
UPC/BARCODE
691195001059
IngredientAmount% DV
Total Carbohydrates0.66 Gram(s)1%
Vitamin B62 mg100%
Selenium2.49 mcg6.6%
Zinc Glycinate12 mg100%
Royal Maca 1000 mg--

Other ingredients: Cellulose, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Certified Organic by BIO LATINA: Grown & Processed in PERU, made by flash heat-extrusion process (gelatinization.)

Certified Organic by BIO LATINA: Grown & Processed in PERU, made by flash heat-extrusion process (gelatinization.) Sun-dried. Fair traded.

Vegan.

No sodium laurel sulfate dusted on capsules. Gluten-free. No additives. Not irradiated.

Made with certified organic Maca Roots

Supports healthy sexual functioning and a healthy prostate when used as part of the daily diet.

Precautions

Native Peruvians NEVER eat raw maca.

Warning: Do not combine this product with a testosterone-blocking drug, like Lupron.

Your total zinc supplements should not exceed 30 mg daily.

Formula

Lepidium meyenii/peruvianum Made with certified organic Maca Roots Maca formula concentrate (507 mg.)

FDA Statement of Identity

Dietary Supplement

Storage

Directions: (Do not refrigerate)

Suggested/Recommended/Usage/Directions

Directions: (Do not refrigerate) Immediate & urgent use: take 4-8 caps/day for same day effects. Maintenance: Take 2-6 caps daily depending on age, health condition and individual sensitivity. If side effects appear, such as headache, loss of libido, etc. take every other day or reduce dosage. Note: Men who are taking a zinc supplement of 20 mg, or more should take Royal Maca Vitality Caps or Royal Maca Powder

FDA Disclaimer Statement

These statement have not been evaluated by the F.D.A. This product is not intended to treat, prevent, or cure any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Royal Maca for Men Vegetarian Capsules by Whole World Botanicals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Royal Maca for Men Vegetarian Capsules label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Royal Maca for Men Vegetarian Capsules by Whole World Botanicals

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B6

Interacts with
210 drugs
2 mg per serving

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is b...

Vitamin B6 monograph & interactions

Selenium

Interacts with
321 drugs
2.49 mcg per serving Form: Maca

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...

Selenium monograph & interactions

Zinc Glycinate

Interacts with
67 drugs
12 mg per serving

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...

Zinc Glycinate monograph & interactions

Royal Maca

No known
interactions
1000 mg per serving Form: Maca Root Concentrate

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Royal Maca monograph & interactions

Other (inactive) ingredients: Cellulose, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Royal Maca for Men Vegetarian Capsules by Whole World Botanicals Drug Interactions

Want to check YOUR meds against Royal Maca for Men Vegetarian Capsules?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
561Drugs
521 Moderate 40 Minor

Ingredients driving the most interactions

Selenium 321
Vitamin B6 210
Zinc Glycinate 67

Individual Drug Interactions

The ingredients in Royal Maca for Men Vegetarian Capsules interact with 561 drugs. Click any drug to see the details.

3 of the 4 ingredients in Royal Maca for Men Vegetarian Capsules interact with drugs. Each result below shows which ingredient is responsible. Selenium Vitamin B6 Zinc Glycinate

Each ingredient & the kinds of drugs it affects

For each ingredient in Royal Maca for Men Vegetarian Capsules with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Selenium6 drug types · 321 drugs

Anticoagulant/Antiplatelet Drugs

Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.

Likelihood Possible Evidence D
Barbiturates

Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.

Likelihood Possible Evidence D
Contraceptive Drugs

Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.

Likelihood Possible Evidence B
Niacin

Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Selenium full monograph & interactions

Vitamin B65 drug types · 210 drugs

Amiodarone (Cordarone)

Theoretically, vitamin B6 might increase the photosensitivity caused by amiodarone.
Despite initial case reports suggesting that pyridoxine may have a protective effect against amiodarone-induced photosensitivity, preliminary clinical research suggests that pyridoxine may actually exacerbate this adverse effect.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, vitamin B6 may have additive effects when used with antihypertensive drugs.
Research in hypertensive rats shows that vitamin B6 can decrease systolic blood pressure. Similarly, clinical research in patients with hypertension shows that taking high doses of vitamin B6 may reduce systolic and diastolic blood pressure, possibly by reducing plasma levels of epinephrine and norepinephrine.

Likelihood Possible Evidence B
Phenobarbital (Luminal)

High doses of vitamin B6 may reduce the levels and clinical effects of phenobarbital.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenobarbital, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenobarbital to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Phenytoin (Dilantin)

High doses of vitamin B6 may reduce the levels and clinical effects of phenytoin.
Preliminary clinical evidence suggests that vitamin B6 200 mg daily can reduce plasma levels of phenytoin, possibly by increasing metabolism. It is not known whether lower doses have any effect. Advise people taking phenytoin to avoid high doses of vitamin B6.

Likelihood Possible Evidence D
Levodopa

Vitamin B6 may increase the metabolism of levodopa when taken alone, but not when taken in conjunction with carbidopa.
Vitamin B6 (pyridoxine) enhances the metabolism of levodopa, reducing its clinical effects. However, this interaction does not occur when carbidopa is used concurrently with levodopa (Sinemet). Therefore, it is not likely to be a problem in most people.

Likelihood Unlikely Evidence D
Vitamin B6 full monograph & interactions

Zinc Glycinate10 drug types · 67 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.

Likelihood Probable Evidence D
Cephalexin (Keflex)

Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.

Likelihood Probable Evidence B
Cisplatin (Platinol-Aq)

Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.

Likelihood Possible Evidence D
Integrase Inhibitors

Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.

Likelihood Possible Evidence D
Penicillamine (Cuprimine, Depen)

Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.

Likelihood Probable Evidence B
Quinolone Antibiotics

Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.

Likelihood Probable Evidence B
Ritonavir (Norvir)

Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.

Likelihood Probable Evidence B
Amiloride (Midamor)

Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.

Likelihood Probable Evidence B
Atazanavir (Reyataz)

Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.

Likelihood Probable Evidence B
Zinc Glycinate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Royal Maca for Men Vegetarian Capsules, from the product label.

Whole World Botanicals

See all Whole World Botanicals products
Name
Whole World Botanicals, Inc.
City
NY
State
NY
ZipCode
10032
Phone Number
(646) 290-8651
Web Address
www.wholeworldbotanicals.com
Pharmacist Counseling Corner

Royal Maca for Men Vegetarian Capsules by Whole World Botanicals: Common Questions

Does Royal Maca for Men Vegetarian Capsules by Whole World Botanicals interact with any medications?
Yes. Based on its ingredients, Royal Maca for Men Vegetarian Capsules has a known interaction with 561 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Royal Maca for Men Vegetarian Capsules contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this have any fillers?
The capsules contain cellulose and purified water as inactive ingredients — these are standard capsule materials. There are no other fillers.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety data on Royal Maca in pregnancy or lactation, so avoid it during both. The vitamin and mineral ingredients (B6, selenium, zinc) have limited pregnancy data on file here — talk with your doctor or pharmacist about whether they're right for you at normal doses if you're planning pregnancy or currently pregnant or breastfeeding.
What is maca, and what does it do?
Maca is a root plant from South America traditionally used as a supplement. Our data shows the evidence for its effects on amenorrhea, anemia, sexual function, athletic performance, and bone health is insufficient to rate — meaning it hasn't been well studied enough to confirm whether it works for these uses.
Can high doses of these ingredients be harmful?
Yes. High-dose vitamin B6 over time can damage your nerves. Excess selenium can cause hair loss, nail damage, and at very high levels, organ failure. Zinc above 40 mg daily raises a theoretical risk of copper deficiency. Stick to recommended amounts unless a doctor advises otherwise.
Is this product safe for daily use?
At recommended doses, the B6, selenium, and zinc are generally well tolerated. Royal Maca is marketed as generally well tolerated as a food, but long-term safety as a supplement form has not been studied. If you have any health conditions or take medications, check with your pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Royal Maca for Men Vegetarian Capsules label
Go deeper

The Full Monographs Behind Royal Maca for Men Vegetarian Capsules’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B6

Interacts with 210 drugs

Vitamin B6 (pyridoxine) is an essential water-soluble vitamin that your body needs for metabolism, brain function, and making red blood cells. It is best known for helping with pregnancy-rel...

Read the full Vitamin B6 monograph → Herb & supplement monograph

Selenium

Interacts with 321 drugs

Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who eat a varied diet get enough, and supple...

Read the full Selenium monograph → Herb & supplement monograph

Zinc

Interacts with 67 drugs

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...

Read the full Zinc monograph → Herb & supplement monograph

Maca

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...

Read the full Maca monograph →
Sources

Sources & How We Checked

Royal Maca for Men Vegetarian Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 157 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B6 32 references
  1. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Geerling BJ, Dagnelie PC, Badart-Smook A, et al. Diet as a risk factor for the development of ulcerative colitis. Am J Gastroenterol 2000;95:1008-13. PubMed
  4. South M. Neonatal seizures after pyridoxine use -- reply. Lancet 1999;354:2083. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  6. Baxter P, Aicardi J. Neonatal seizures after pyridoxine use. Lancet 1999;354:2082-3. PubMed
  7. Bendich A, Cohen M. Vitamin B6 safety issues. Ann N Y Acad Sci 1990;585:321-30.
  8. Schaumburg H, Kaplan J, Windebank A. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. N Engl J Med 1983;309:445-8. PubMed
  9. Gordon N. Pyridoxine dependency: an update. Dev Med Child Neurol 1997;39:63-5. PubMed
  10. Lewis PJ. Pain in the hand and wrist. Pyridoxine supplements may help patients with carpal tunnel syndrome. BMJ 1995;310:1534. PubMed
  11. Kaufman G. Pyridoxine against amiodarone-induced photosensitivity (letter). Lancet 1984;1:51-2. PubMed
  12. Mulrow JP, Mulrow CD, McKenna WJ. Pyridoxine and amiodarone-induced photosensitivity. Ann Intern Med 1985;103:68-9. PubMed
  13. Kawada A, Kashima A, Shiraishi H, et al. Pyridoxine-induced photosensitivity and hypophosphatasia. Dermatology 2000;201:356-60.. PubMed
  14. Vasile A, Goldberg R, Kornberg B. Pyridoxine toxicity: report of a case. J Am Osteopath Assoc 1984;83:790-1. DOI
  15. Hansson O, Sillanpaa M. Pyridoxine and serum concentration of phenytoin and phenobarbitone. Lancet 1976;1:256. DOI
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Selenium 36 references
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See these in context on the Zinc monograph →

Maca 1 reference
  1. Valerio, L. G., Jr. and Gonzales, G. F. Toxicological aspects of the South American herbs cat's claw (Uncaria tomentosa) and Maca (Lepidium meyenii) : a critical synopsis. Toxicol.Rev 2005;24(1):11-35. PubMed

See these in context on the Maca monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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