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Dietary supplement

Royal Strength Ingredients & Drug Interactions

by Physician's Strength

Royal Strength label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Royal Strength against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Royal Strength is a dietary supplement by Physician's Strength with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, skin health and wound care, immune support.Based on those ingredients, 2,027 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are fresh Royal Jelly. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Royal Strength by Physician's Strength

Ask about any prescription or over-the-counter medication and we check it for interactions with Royal Strength by Physician's Strength — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Royal Strength by Physician's Strength

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “fresh Royal Jelly” is listed as a grouped ingredient — the label gives one combined amount (1,300 mg) without saying how much of each component you get.

Royal Strength contains three active ingredients. Fresh royal jelly is a nutrient-rich secretion made by honeybees.

Pumpkin seed oil is extracted from pumpkin seeds and is used for urinary and prostate support. Carob molasses is a sweetener derived from carob pods and is sometimes used for digestive complaints.

The product contains no inactive fillers or other added ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: natural support of adrenal glands.
  • We looked for evidence on: adrenal fatigue, stress resilience, hormonal balance, energy metabolism.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for this product's ingredients is mixed. Pumpkin seed oil is possibly effective for benign prostatic hyperplasia (enlarged prostate), but evidence is insufficient for hair loss, urinary tract infections, interstitial cystitis, or intestinal parasites.

Carob molasses is possibly effective for diarrhea, though evidence is insufficient for athletic performance, blood sugar control, and cholesterol support. We hold no effectiveness data for royal jelly or Preservatol in our current information.

The evidence, ingredient by ingredient Royal Jelly Pumpkin Carob

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pumpkin seed oil in food amounts is generally well tolerated, though concentrated supplements carry some caution. The most common side effects are mild abdominal discomfort, diarrhea, nausea, and vomiting.

Rarely, anaphylaxis has been reported. There are isolated case reports of hair loss following consumption of bitter-tasting or wild pumpkin due to high cucurbitacin content.

Carob is considered safe in normal food amounts but has limited safety data at concentrated supplement doses. In infants, carob thickeners have rarely been linked to serious digestive complications.

For pregnancy and breastfeeding, there is not enough safety data on concentrated supplements of either ingredient — talk with your doctor or pharmacist about whether this product is right for you.

Side effects, ingredient by ingredient Royal Jelly Pumpkin Carob

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Carob, Pumpkin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 2,023 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start Royal Strength, double-check with your doctor or pharmacist if you take lithium — pumpkin seed oil might raise its levels and require a dose change. Also confirm the timing of any other oral medications you take, since carob molasses may interfere with how your body absorbs them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Royal Strength may appeal to you if you're interested in prostate or digestive support, but take care if you take lithium or other oral medications — space doses and check with your own doctor or pharmacist first. If you're pregnant or breastfeeding, ask your healthcare provider whether the concentrated ingredients in this liquid are appropriate for you.

This isn't a decision to make on your own.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Royal Strength, straight from the product label.

Brand Physician's Strength
Barcode (UPC) 850032454391
Net contents 2 Ounce(s); 60 mL
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 268962
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Royal Strength by Physician's Strength, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.5 Teaspoon(s)
Maximum serving Sizes:
0.5 Teaspoon(s)
UPC/BARCODE
850032454391
IngredientAmount% DV
fresh Royal Jelly1300 mg--
Preservatol0 NP--
Pumpkin seed Oil0 NP--
Carob Molasses0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Take 1/ teaspoon or more as often as needed under the tongue. Always use a clean spoon to avoid contamination. If contents separate, stir before use.

Royal Strength is the most powerful raw stabilized royal jelly available. For natural support of adrenal glands take it under the tongue or add it to smoothies, juice, or hot cereals. Great source of natural nutrients.

Storage

No need to refrigerate.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formula

Concentrated royal jelly

Formulation

Doctor's formula

Non-GMO

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Royal Strength by Physician's Strength label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Royal Strength label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Royal Strength by Physician's Strength

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.5 Teaspoon(s) Dosage formLiquid Amounts shown are per serving.

Fresh Royal Jelly

Interacts with
174 drugs
1300 mg per serving

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune su...

Fresh Royal Jelly monograph & interactions
Interaction report

Royal Strength by Physician's Strength Drug Interactions

Want to check YOUR meds against Royal Strength?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,027Drugs
175 Moderate 1,852 Minor

Ingredients driving the most interactions

fresh Royal Jelly 174

Individual Drug Interactions

The ingredients in Royal Strength interact with 2,027 drugs. Click any drug to see the details.

1 of the 1 ingredient in Royal Strength interact with drugs. Each result below shows which ingredient is responsible. fresh Royal Jelly

Each ingredient & the kinds of drugs it affects

For each ingredient in Royal Strength with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

fresh Royal Jelly2 drug types · 174 drugs

Antihypertensive Drugs

Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that royal jelly might lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.

Likelihood Possible Evidence D
fresh Royal Jelly full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Royal Strength, from the product label.

Physician's Strength

See all Physician's Strength products
Name
Physician's Strength
Street Address
13900 W. Polo Trail Drive
City
Lake Forest
State
IL
ZipCode
60045
Phone Number
1-800-473-8460
Web Address
www.physicians-strength.com
Pharmacist Counseling Corner

Royal Strength by Physician's Strength: Common Questions

Does Royal Strength by Physician's Strength interact with any medications?
Yes. Based on its ingredients, Royal Strength has a known interaction with 2,027 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Royal Strength contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does royal jelly have any drug interactions I should know about?
Royal jelly in this product is listed as a blend, with its component ingredients detailed individually. We don't hold a separate monograph for royal jelly itself, so its interaction profile comes through those parts. Check with your doctor or pharmacist about your specific medications.
What are the most common side effects of pumpkin seed oil?
Mild abdominal discomfort, diarrhea, nausea, and vomiting are the most common. Anaphylaxis is rare. In isolated cases, bitter-tasting or wild pumpkins high in cucurbitacin have caused hair loss, though this is not typical of cultivated pumpkin seed oil.
Is carob molasses safe while pregnant or breastfeeding?
There isn't enough safety data on concentrated carob supplements during pregnancy or breastfeeding. Talk with your doctor or pharmacist about whether this product is safe for you in your individual situation.
Can I take this if I'm on other oral medications?
Carob molasses in this product may slow down how your body absorbs other oral drugs. If you take this product, space it at least 30 to 60 minutes apart from your other medications, and confirm the timing with your pharmacist or doctor first.
What is pumpkin seed oil used for?
Pumpkin seed oil is possibly effective for benign prostatic hyperplasia, which is enlargement of the prostate gland. Evidence is not yet reliable for hair loss, urinary tract infections, or other uses listed on this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Royal Strength label
Go deeper

The Full Monographs Behind Royal Strength’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Royal Jelly

Interacts with 174 drugs

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune support, but solid human evidence is limit...

Read the full Royal Jelly monograph → Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph → Herb & supplement monograph

Carob

Interacts with 2,022 drugs

Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum). It is mostly eaten as a food and is generally w...

Read the full Carob monograph →
Sources

Sources & How We Checked

Royal Strength's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 28 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Royal Jelly 14 references
  1. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
  2. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
  3. Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
  4. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
  5. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
  6. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
  7. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
  8. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
  9. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  10. Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
  11. Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
  12. Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
  13. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
  14. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

See these in context on the Royal Jelly monograph →

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Carob 9 references
  1. Savino, F., Muratore, M. C., Silvestro, L., Oggero, R., and Mostert, M. Allergy to carob gum in an infant. J.Pediatr.Gastroenterol.Nutr. 1999;29(4):475-476. DOI
  2. Bosscher, D., Caillie-Bertrand, M., and Deelstra, H. Effect of thickening agents, based on soluble dietary fiber, on the availability of calcium, iron, and zinc from infant formulas. Nutrition 2001;17(7-8):614-618. PubMed
  3. van, der Brempt, X, Ledent, C., and Mairesse, M. Rhinitis and asthma caused by occupational exposure to carob bean flour. J.Allergy Clin.Immunol. 1992;90(6 Pt 1):1008-1010. PubMed
  4. Clarke, P. and Robinson, M. J. Thickening milk feeds may cause necrotising enterocolitis. Arch Dis.Child Fetal Neonatal Ed 2004;89(3):F280. PubMed
  5. Harmuth-Hoene, A. E. and Schelenz, R. Effect of dietary fiber on mineral absorption in growing rats. J Nutr 1980;110(9):1774-1784. PubMed
  6. Scoditti, A., Peluso, P., Pezzuto, R., Giordano, T., and Melica, A. Asthma to carob bean flour. Ann.Allergy Asthma Immunol. 1996;77(1):81. PubMed
  7. Komericki P, Kränke B. Immediate hypersensitivity to carob pods. Contact Dermatitis. 2009;61(4):239-40. PubMed
  8. Bosscher D, Van Caillie-Bertrand M, Van Cauwenbergh R, Deelstra H. Availabilities of calcium, iron, and zinc from dairy infant formulas is affected by soluble dietary fibers and modified starch fractions. Nutrition. 2003;19(7-8):641-5. PubMed
  9. Jedrzejczyk M, Bartnik K, Funkowicz M, Toporowska-Kowalska E. FPIES Induced by Locust Bean Gum in an Infant. J Investig Allergol Clin Immunol. 2020;30(3):197-199. PubMed

See these in context on the Carob monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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