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Dietary supplement

Sea Buckthorn 400 mg Ingredients & Drug Interactions

by Eclectic Herb

Sea Buckthorn 400 mg label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sea Buckthorn 400 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sea Buckthorn 400 mg is a dietary supplement by Eclectic Herb with 2 active ingredients. Its ingredients are commonly taken for skin health and dryness, dry eye symptoms, digestive complaints.Based on those ingredients, 408 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sea Buckthorn, Larix Arabinogalactan Juice, Freeze-Dried. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sea Buckthorn 400 mg by Eclectic Herb

Ask about any prescription or over-the-counter medication and we check it for interactions with Sea Buckthorn 400 mg by Eclectic Herb — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sea Buckthorn 400 mg by Eclectic Herb

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients. Sea buckthorn is a berry extract used traditionally for skin health and wound healing.

Larch arabinogalactan (freeze-dried juice) is a soluble fiber from larch tree wood. The capsule also contains hypromellose, an inactive ingredient that makes up the capsule shell.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Sea buckthorn whole herb concentrate.
  • We looked for evidence on: Dry skin, Dry eye, Dyspepsia, Wound healing, Aging skin, Wrinkled skin — and 4 related terms.
  • The strongest evidence on file: Sea Buckthorn is rated "Possibly Effective" for Burns (Natural Medicines).
  • Also on file: Sea Buckthorn is rated "Possibly Ineffective" for Atopic dermatitis (eczema).
  • Also on file: Sea Buckthorn is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Radiation dermatitis, Dry eye, Dry skin, and more.

Sea buckthorn is possibly effective for burns based on available evidence. For eczema (atopic dermatitis), the evidence suggests it's possibly ineffective.

For other uses listed — high cholesterol (dyslipidemia), aging skin, and cancer — the evidence we hold is insufficient to rate it either way. For larch arabinogalactan, we don't have enough reliable evidence to rate its effectiveness for the common cold or high cholesterol.

Both ingredients lack strong proof of benefit for most of their studied uses.

The evidence, ingredient by ingredient Sea Buckthorn Larch Arabinogalactan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sea buckthorn is generally well tolerated as a food, but supplement safety hasn't been fully studied, so use caution. At very high doses, it can cause yellow staining of the skin; one person who took 100 grams daily for 6 months developed generalized yellowing.

Applied to skin, it may rarely cause dryness, redness, rash, or irritation. Larch arabinogalactan is generally well tolerated as a fiber, though some people experience bloating and gas.

Long-term safety data for both ingredients are limited. There isn't enough data to know whether either ingredient is safe during breastfeeding — talk with your doctor or pharmacist before using if you're nursing.

The facts don't contain pregnancy safety information, so discuss that with your provider too.

Side effects, ingredient by ingredient Sea Buckthorn Larch Arabinogalactan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Sea Buckthorn, Larch Arabinogalactan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 408 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check your blood thinners and antiplatelet drugs (like warfarin, clopidogrel, or aspirin) — sea buckthorn may raise bleeding risk. Also check any blood pressure medications you take, since sea buckthorn itself can lower blood pressure.

If you're on immunosuppressants after a transplant or for an autoimmune condition, ask your pharmacist — larch arabinogalactan may interfere with how well they work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product might be worth considering if you're interested in burns or general skin support and don't take blood thinners, blood pressure drugs, or immune-suppressing medications. If you're on any of those — or any prescription medication — check it against our tool first.

Talk to your pharmacist before starting, especially if you're pregnant, breastfeeding, or take immunosuppressants.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sea Buckthorn 400 mg, straight from the product label.

Brand Eclectic Herb
Barcode (UPC) 023363309627
Net contents 90 Veg Cap(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 316876
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sea Buckthorn 400 mg by Eclectic Herb, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Cap(s)
Maximum serving Sizes:
3 Veg Cap(s)
Servings per container
90
UPC/BARCODE
023363309627
IngredientAmount% DV
Sea Buckthorn353 mg--
Larix Arabinogalactan Juice, Freeze-Dried47 mg--

Other ingredients: Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Concentrated 7X through freeze-drying Freeze dried for peak plant power

No fillers Non GMO Gluten free

Vegan

Freeze-drying is the best method of preservation as it naturally concentrates the nutrients in the plant by removing only the water. Grown in the United States Naturally Concentrated

Nothing artificial - no fillers or additives.

Promotes healthy skin Small batch freeze dried

Formula

Whole herb Raw food

100% Kosher

Our sea buckthorn is locally grown and fresh freeze-dried in-house in small batches.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1-3 capsules per day.

Precautions

Keep away from children. Consult your doctor about herbs with pregnancy, infants or prescription drugs

Consult your doctor about herbs with pregnancy, infants or prescription drugs

General Statements

@eclecticherb

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sea Buckthorn 400 mg by Eclectic Herb label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sea Buckthorn 400 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sea Buckthorn 400 mg by Eclectic Herb

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veg Cap(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sea Buckthorn

Interacts with
289 drugs
353 mg per serving

Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Earl...

Sea Buckthorn monograph & interactions

Larix Arabinogalactan Juice, Freeze-Dried

Interacts with
121 drugs
47 mg per serving Form: Larix Arabinogalactan Juice, Freeze-Dried, Larix Arabinogalactan Juice, Freeze-Dried

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...

Larix Arabinogalactan Juice, Freeze-Dried monograph & interactions

Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sea Buckthorn 400 mg by Eclectic Herb Drug Interactions

Want to check YOUR meds against Sea Buckthorn 400 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
408Drugs
408 Moderate

Ingredients driving the most interactions

Sea Buckthorn 289
Larix Arabinogalactan Juice, Freeze-Dried 121

Individual Drug Interactions

The ingredients in Sea Buckthorn 400 mg interact with 408 drugs. Click any drug to see the details.

2 of the 2 ingredients in Sea Buckthorn 400 mg interact with drugs. Each result below shows which ingredient is responsible. Sea Buckthorn Larix Arabinogalactan Juice, Freeze-Dried

Each ingredient & the kinds of drugs it affects

For each ingredient in Sea Buckthorn 400 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sea Buckthorn2 drug types · 289 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that sea buckthorn fruit extracts can inhibit platelet aggregation and adhesion to collagen and fibrinogen.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking sea buckthorn with antihypertensive drugs might increase the risk of hypotension.
Taking sea buckthorn appears to reduce blood pressure in some patients.

Likelihood Possible Evidence D
Sea Buckthorn full monograph & interactions

Larix Arabinogalactan Juice, Freeze-Dried1 drug type · 121 drugs

Immunosuppressants

Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.

Likelihood Possible Evidence D
Larix Arabinogalactan Juice, Freeze-Dried full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sea Buckthorn 400 mg, from the product label.

Eclectic Herb

See all Eclectic Herb products
Name
Eclectic Herb
Street Address
755 NE 6th St.
City
Gresham
State
OR
ZipCode
97030
Phone Number
503-668-4120
Web Address
eclecticherb.com
Pharmacist Counseling Corner

Sea Buckthorn 400 mg by Eclectic Herb: Common Questions

Does Sea Buckthorn 400 mg by Eclectic Herb interact with any medications?
Yes. Based on its ingredients, Sea Buckthorn 400 mg has a known interaction with 408 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sea Buckthorn 400 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this turn my skin yellow?
High doses of sea buckthorn can cause yellow staining of the skin, especially with very high amounts over months. The 400 mg dose in this product is much smaller than the 100 grams daily that caused yellowing in one reported case, but it's still something to watch for if you take it long-term.
What's larch arabinogalactan for?
It's a soluble fiber from larch tree wood. The facts we hold don't show strong evidence it works for the common cold or cholesterol, but it's generally well tolerated — though some people notice bloating or gas.
Can I take this while breastfeeding?
There isn't enough safety data to know whether it's okay while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you during nursing.
Is this safe long-term?
Sea buckthorn is generally well tolerated as a food, but long-term supplement safety hasn't been fully studied. Same with larch arabinogalactan — we have limited long-term data. Ask your pharmacist about how long you plan to take it.
What does sea buckthorn actually do?
It's possibly effective for burns based on the evidence we hold. For eczema, the research suggests it's not likely to help. For aging skin, high cholesterol, and cancer, we don't have enough good evidence to say either way.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Sea Buckthorn 400 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sea Buckthorn 400 mg label
Go deeper

The Full Monographs Behind Sea Buckthorn 400 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sea Buckthorn

Interacts with 289 drugs

Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Early research is promising for a few uses l...

Read the full Sea Buckthorn monograph → Herb & supplement monograph

Larch Arabinogalactan

Interacts with 121 drugs

Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...

Read the full Larch Arabinogalactan monograph →
Sources

Sources & How We Checked

Sea Buckthorn 400 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sea Buckthorn 7 references
  1. Johansson AK, Korte H, Yang B, et al. Sea buckthorn berry oil inhibits platelet aggregation. J Nutr Biochem 2000;11:491-5.. PubMed
  2. Grad, S. C., Muresan, I., and Dumitrascu, D. L. Generalized yellow skin caused by high intake of sea buckthorn. Forsch.Komplementmed. 2012;19(3):153-156. PubMed
  3. Vlasov, V. V. [Hippophae oil in the treatment of superficial skin burns]. Vestn.Dermatol Venerol. 1970;44(6):69-72.
  4. Chang BB, Wang F Xu TY Zhang QQ He J Zhang XJ Li J. Total flavones of Hippophae rhamnoides L. for essential hypertension: a systematic review of randomized controlled trials. Chinese Journal of Evidence-Based Medicine. 2009;9(11):1207-1213. DOI
  5. Olas B, Kontek B, Szczesna M, et al. Inhibition of blood platelet adhesion by phenolics rich fraction of Hippophae rhamnoides L. fruits. J Physiol Pharmacol. 2017;68(2):223-9.
  6. Larmo P, Järvinen R, Laihia J, et al. Effects of a sea buckthorn oil spray emulsion on dry eye. Cont Lens Anterior Eye. 2019;42(4):428-433. PubMed
  7. De Seta F, Caruso S, Di Lorenzo G, Romano F, Mirandola M, Nappi RE. Efficacy and safety of a new vaginal gel for the treatment of symptoms associated with vulvovaginal atrophy in postmenopausal women: A double-blind randomized placebo-controlled study. Ma PubMed

See these in context on the Sea Buckthorn monograph →

Larch Arabinogalactan 8 references
  1. D'Adamo P. Larch arabinogalactan. J Naturopath Med 1996;6:33-7.
  2. Kelly GS. Larch arabinogalactan: Clinical relevance of a novel immune-enhancing polysaccharide. Alt Med Rev 1999;4:96-103.
  3. Marett R, Slavin JL. No long-term benefits of supplementation with arabinogalactan on serum lipids and glucose. J Am Diet Assoc 2004;104:636-9.
  4. Robinson RR, Feirtag J, Slavin JL. Effects of dietary arabinogalactan on gastrointestinal and blood parameters in healthy human subjects. J Am Coll Nutr 2001;20:279-85. PubMed
  5. Udani JK, Singh BB, Barrett ML, Singh VJ. Proprietary arabinogalactan extract increases antibody response to the pneumonia vaccine: a randomized, double-blind, placebo-controlled, pilot study in healthy volunteers. Nutr J 2010;9:32. PubMed
  6. Grube B, Stier H, Riede L, Gruenwald J. Tolerability of a proprietary larch arabinogalactan extract: a randomized, double-blind, placebo-controlled clinical trial in healthy subjects. Food Nutr Sci 2012;3:1533-8. DOI
  7. Dion C, Chappuis E, Ripoll C. Does larch arabinogalactan enhance immune function? A review of mechanistic and clinical trials. Nutr Metab (Lond) 2016;13:28. PubMed
  8. Riede L, Grube B, Gruenwald J. Larch arabinogalactan effects on reducing incidence of upper respiratory tract infections. Curr Med Res Opin 2013;29(3):251-8.

See these in context on the Larch Arabinogalactan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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