Sea Kelp 325 mcg Ingredients & Drug Interactions
by NusaPure
What is this page for?
First and foremost: checking Sea Kelp 325 mcg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Sea Kelp 325 mcg is a dietary supplement by NusaPure with 2 active ingredients. Its ingredients are commonly taken for preventing iodine deficiency, supporting thyroid hormone production, general energy and metabolism support.Based on those ingredients, 891 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Kelp, Iodine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Sea Kelp 325 mcg by NusaPure
Ask about any prescription or over-the-counter medication and we check it for interactions with Sea Kelp 325 mcg by NusaPure — and tell you which ingredient is responsible.
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HelloPharmacist Scorecard of Sea Kelp 325 mcg by NusaPure
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Sea Kelp 325 mcg contains 2 active ingredients: iodine and kelp (Fucus vesiculosus), a brown seaweed rich in iodine. Iodine is an essential mineral your body needs for thyroid function and healthy metabolism.
The product also includes inactive ingredients — cellulose, silica, and rice flour — that serve as capsule filler and binder.
Does it work?
Strong evidence
Iodine in this product is likely effective for preventing or treating iodine deficiency and protecting the thyroid after radiation exposure. It's possibly effective for oral inflammation (oral mucositis) and gum disease (periodontitis).
Kelp's effectiveness isn't well established in the data we hold — evidence is insufficient to rate its use for aging skin, heart health, constipation, diarrhea, or indigestion.
How safe is it?
Well-documented data
Iodine is well tolerated in normal dietary amounts, but high doses can disrupt thyroid function. Common side effects at higher intakes include stomach upset, diarrhea, goiter (enlarged thyroid), headache, metallic taste, and nausea; rarely, hypersensitivity reactions can occur.
Kelp carries similar risks — its high iodine content can cause goiter, hyperthyroidism, or hypothyroidism — and it may concentrate heavy metals from seawater. The safety data advises against kelp in pregnancy due to excess iodine and possible heavy metal exposure; iodine itself should be used only at amounts your doctor recommends.
Kelp should be avoided while breastfeeding, since iodine passes into breast milk and may affect your baby's thyroid.
Meds to double-check
Moderate interaction found
Double-check this product with your doctor or pharmacist if you take lithium, antithyroid drugs (like methimazole or propylthiouracil), amiodarone (Cordarone), or thyroid hormone replacement — all carry Moderate interaction potential from the iodine and kelp. If you take blood thinners (anticoagulants) or any medications processed through the liver (CYP2D6, CYP2C9, or CYP3A4 substrates), minor interactions from kelp are theoretically possible but not yet confirmed in humans.
The bottom line
Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product makes sense if you have a documented iodine deficiency and your doctor has recommended supplementation. If you take lithium, any antithyroid drug, amiodarone, or thyroid hormone replacement, check with your doctor or pharmacist before starting — the iodine content can interfere with how these medications work.
If you're pregnant, breastfeeding, or have a history of thyroid problems, talk it over with your own doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Sea Kelp 325 mcg, straight from the product label.
| Brand | NusaPure |
|---|---|
| Barcode (UPC) | X001MLQ6CN |
| Net contents | 200 Veg Cap(s) |
| Market status | On market |
| Date entered into DSLD | Jun 20, 2024 |
| DSLD ID | 307391 |
| Product type | Botanical With Nutrients |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Sea Kelp 325 mcg by NusaPure, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Iodine | 325 mcg | 216.67% |
| Kelp | 65 mg | -- |
Other ingredients: Cellulose, Silica, Rice Flour
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
New
Suggested/Recommended/Usage/Directions
Directions: Take one (1) capsule daily, preferably with a meal.
Precautions
Warning: For adults only.
Consult physician if pregnant/nursing, taking medication (especially thyroid medications), taking other iodine supplements, or have a medical condition (especially any thyroid disorder).
Discontinue use and consult your doctor if any adverse reactions occur.
Keep out of reach of children.
Allergen information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Premium Quality Assembled in USA GMO free Made with Non-GMO ingredients Gluten free FDA Registered Facility
Manufactured in a cGMP inspected facility
Formula
Sea Kelp 325 mcg Natural iodine
Formulation
Assembled in USA Tested Supports normal nutritional supplementation Guaranteed quality, laboratory tested Made under strict GMP guidelines
Suitable for vegetarians/vegans
Allergen information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. GMO free Made with Non-GMO ingredients
Natural color variation may occur in this product.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Sea Kelp 325 mcg by NusaPure label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Sea Kelp 325 mcg by NusaPure
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container200 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Iodine
Interacts with7 drugs
Iodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements...
Iodine monograph & interactionsKelp
Interacts with891 drugs
Fucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is l...
Kelp monograph & interactionsOther (inactive) ingredients: Cellulose, Silica, Rice Flour. These complete the product’s ingredient list but are not active constituents.
Sea Kelp 325 mcg by NusaPure Drug Interactions
HelloPharmacist Interaction Report
Sea Kelp 325 mcg by NusaPure carries documented interactions through both its iodine and kelp (Fucus vesiculosus) content.
The most serious concern involves lithium — a mood-stabilizing medication — where both ingredients may trigger additive effects on the thyroid (hypothyroidism from iodine, or paradoxically hyperthyroidism from kelp), requiring close thyroid monitoring if you take lithium.
Read the full breakdown — every affected drug type, severity by severity
You'll also want to flag any antithyroid medications, amiodarone (a heart rhythm drug), and thyroid hormone replacement. Iodine and kelp can both shift how your thyroid works, potentially blunting or amplifying the effect of these medications.
Kelp adds theoretical concerns with blood thinners (anticoagulants) and several enzyme substrates — interactions not yet reported in humans but shown in lab studies.
Altogether, these interactions span 892 individual medications. If you take any prescription medication for your thyroid, heart, mood, or blood clotting, run your exact medication list through the checker below before adding this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Sea Kelp 325 mcg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Sea Kelp 325 mcg interact with 891 drugs. Click any drug to see the details.
2 of the 2 ingredients in Sea Kelp 325 mcg interact with drugs. Each result below shows which ingredient is responsible. Kelp Iodine
Amitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
Read the full Kelp + Amlodipine, Celecoxib interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphetamineAdensys XR-ODT, Adzenys ER, Dyanavel XR, Mydayis
How Amphetamine interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Amphetamine interactionAmphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine SulfateAdderall, Adderall XR
How Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Amphetamine Aspartate, Amphetamine Sulfate, Dextroamphetamine Saccharate, Dextroamphetamine Sulfate interactionAmphetamine SulfateBenzedrine, Evekeo ODT
How Amphetamine Sulfate interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Amphetamine Sulfate interactionAmprenavirAgenerase
How Amprenavir interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Amprenavir interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Antithrombin Iii interactionApalutamideErleada
How Apalutamide interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2c8 (cyp2c8) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Apalutamide interactionApixabanEliquis
How Apixaban interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Apixaban interactionApremilastOtezla
How Apremilast interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Apremilast interactionAprepitantCinvanti, Emend
How Aprepitant interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Aprepitant interactionArgatrobanArgatroban
How Argatroban interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Argatroban interactionAripiprazoleAbilify, Abilify Maintena, Abilify Mycite
How Aripiprazole interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Aripiprazole interactionAripiprazole LauroxilAristada, Aristada Initio Kit
How Aripiprazole Lauroxil interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
Read the full Kelp + Aripiprazole Lauroxil interactionArmodafinilNuvigil
How Armodafinil interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Armodafinil interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
Read the full Kelp + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with Sea Kelp 325 mcg — through 1 ingredient. Tap an ingredient for the detail:
KelpCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs +1 Minor
Interaction Summary
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
Read the full Kelp + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Sea Kelp 325 mcg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Kelp
Amiodarone (Cordarone)
Theoretically, combining Fucus vesiculosus with amiodarone might cause excessively high iodine levels.
Fucus vesiculosus contains high concentrations of iodine. Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Due to its iodine content, Fucus vesiculosus might alter the effects of antithyroid drugs.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Concomitant use of Fucus vesiculosus and lithium has resulted in hyperthyroidism.
There is a case of hyperthyroidism occurring in a patient taking Fucus vesiculosus and lithium. Monitor thyroid hormones closely in patients taking lithium and Fucus vesiculosus concomitantly.
Thyroid Hormone
Due to its iodine content, Fucus vesiculosus might alter the effects of thyroid hormone.
Fucus vesiculosus contains high concentrations of iodine. Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking Fucus vesiculosus while using thyroid hormone could alter the effects of thyroid hormone.
Anticoagulant/Antiplatelet Drugs
Theoretically, taking Fucus vesiculosus with antiplatelet or anticoagulant drugs might increase the risk of bruising and bleeding.
In vitro evidence suggests that a constituent of Fucus vesiculosus, known as fucoidan, has anticoagulant effects. However, in clinical research, fucoidan does not seem to have significant anticoagulant activity when taken orally, possibly due to poor absorption.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C8 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C8. This interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2C9 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP2C9. This interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP2D6 substrates might alter the effects of these substrates.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, both inhibits and induces CYP2D6. This interaction has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, concomitant use of Fucus vesiculosus with CYP3A4 substrates might increase the risk for adverse effects.
In vitro research shows that fucoidan, a constituent of Fucus vesiculosus, inhibits CYP3A4. This interaction has not been reported in humans.
Iodine
Amiodarone (Cordarone)
Combining iodine with amiodarone might cause excessively high iodine levels.
Amiodarone contains 37.3% iodine and can increase iodine levels. Concomitant use with iodine might increase the risk of having excessive iodine levels and adversely affecting thyroid function. Monitor thyroid function.
Antithyroid Drugs
Iodine might alter the effects of antithyroid drugs.
Iodine in high doses has been reported to cause both hyperthyroidism and hypothyroidism, depending on the individual's past medical history. Taking iodine while using antithyroid drugs could alter the effects of the antithyroid drugs.
Lithium
Combining iodine with lithium might have additive hypothyroid effects.
Lithium can inhibit thyroid function. Several case reports suggest that concomitant use of lithium and potassium iodide can reduce thyroid function in otherwise healthy adults. Monitor thyroid function.
Brand information
Manufacturer and brand details for Sea Kelp 325 mcg, from the product label.
NusaPure
See all NusaPure products- Name
- Gmax Central, LLC
- Street Address
- 500 Westover Dr. #92909
- City
- Sanford
- State
- NC
- ZipCode
- 27330
Sea Kelp 325 mcg by NusaPure: Common Questions
Does Sea Kelp 325 mcg by NusaPure interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm pregnant or breastfeeding?
What are the most common side effects?
Is this the right product if I have low iodine?
What is kelp and why is it in this product?
Will this affect my thyroid medication?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Sea Kelp 325 mcg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Sea Kelp 325 mcg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Iodine
Interacts with 7 drugsIodine is an essential mineral your body needs to make thyroid hormones, and most people get enough from iodized salt, dairy, and seafood. Supplements help when you are truly deficient, but...
Read the full Iodine monograph → Herb & supplement monographFucus Vesiculosus
Interacts with 891 drugsFucus vesiculosus (bladderwrack) is a brown seaweed rich in iodine that has been used traditionally for thyroid concerns, weight, and skin. There is little solid human evidence to support mo...
Read the full Fucus Vesiculosus monograph →Sources & How We Checked
Sea Kelp 325 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Iodine 26 references
- McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
- Goodman GA, Rall TW, Nies AS, Taylor P. The Pharmacological Basis of Therapeutics, 9th ed.
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