Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Seabuckthorn SAP Ingredients & Drug Interactions

by NFH

Seabuckthorn SAP label
See full label image
Softgel Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Seabuckthorn SAP against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Seabuckthorn SAP is a dietary supplement by NFH with 2 active ingredients. Its ingredients are commonly taken for skin health and dryness, dry eye symptoms, digestive complaints.Based on those ingredients, 289 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Seabuckthorn Fruit Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Seabuckthorn SAP by NFH

Ask about any prescription or over-the-counter medication and we check it for interactions with Seabuckthorn SAP by NFH — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Seabuckthorn SAP by NFH

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Seabuckthorn SAP contains 2 active ingredients: seabuckthorn fruit oil and seabuckthorn seed oil. Both come from the seabuckthorn berry, a nutrient-dense plant traditionally used to support skin and wound healing.

The product also contains inactive ingredients — vitamin E, gelatin, glycerin, and purified water — which serve as the capsule shell and preservative.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Sea Buckthorn's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: source of omega-7 fatty acids for health.
  • We looked for evidence on: Dyslipidemia, Dry eye, Dry skin, Wrinkled skin, Aging skin, cardiovascular health — and 1 related terms.
  • The closest evidence on file: Sea Buckthorn is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Sea Buckthorn is rated "Insufficient Reliable Evidence To Rate" for Dry eye, Dry skin, Dyslipidemia, Wrinkled skin.

The evidence for seabuckthorn breaks down like this. For burns, it's rated possibly effective — the data suggests it may help, but more research would strengthen that claim.

For eczema (atopic dermatitis), it's rated possibly ineffective based on current studies. For high cholesterol (dyslipidemia), aging skin, and cancer, there isn't enough reliable evidence yet to know whether it works.

The evidence, ingredient by ingredient Sea Buckthorn

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Seabuckthorn is generally well tolerated as a food, but supplement safety hasn't been fully studied, so we don't know the long-term picture at higher doses. At high doses — one person took 100 grams daily for 6 months — sea buckthorn can stain your skin yellow.

Rash was reported in 4% of patients in clinical trials. There isn't enough reliable safety data on supplement use while breastfeeding, so if you're nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Sea Buckthorn

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sea Buckthorn.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 289 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Seabuckthorn SAP, check with your doctor or pharmacist if you take blood pressure-lowering drugs (Moderate risk of low blood pressure) or blood thinners and antiplatelet drugs like warfarin or aspirin (Moderate risk of increased bleeding). These are the main medication types affected by this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Seabuckthorn SAP may be worth considering if you're interested in wound healing support and don't take blood pressure or blood-thinning medications. If you're on those drugs, or any prescription at all, check with your doctor or pharmacist first — the interactions are real and could affect how your medications work.

This supplement is more established as a food than as a high-dose supplement, so the safety data is limited.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Seabuckthorn SAP, straight from the product label.

Brand NFH
Barcode (UPC) 856711011169
Net contents 30 Softgel(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 273359
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Seabuckthorn SAP by NFH, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
856711011169
IngredientAmount% DV
Seabuckthorn Fruit Oil600 mg--
Seabuckthorn Seed Oil400 mg--

Other ingredients: Vitamin E, Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Seabuckthorn SAP is a source of omega-7 fatty acids. Seabuckthorn seed oil provides essential fatty acids for the maintenance of good health.

Seabuckthorn oil

Formulation

All ingredients listed for this product lot number have been tested by a third-arty laboratory for identity, potency, and purity.

Contains no: Gluten, soy, wheat, corn, eggs, dairy, yeast, citrus, preservatives, artificial flavor or color, starch, or sugar.

This product is non-GMO.

Color, size and smell may vary from one lot to another.

All oils are supercritical CO2 extracted from organically grown berries on the qinghai-tibetan plateau.

Suggested/Recommended/Usage/Directions

Directions for use: Adults: Take 1 softgel daily or as directed by your healthcare practitioner. Duration of use: Consult a healthcare practitioner for use beyond 3 months.

Precautions

Cautions and warnings: Consult a healthcare practitioner prior to use if you are pregnant or breast-feeding; or if you are taking blood thinners or medication or natural health products that could increase the risk of bleeding.

Known adverse reactions: Hypersensitivity / allergy is known to occur; in which case, discontinue use.

Do not use if seal is broken.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General Statements

NPN 80056486

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Seabuckthorn SAP by NFH label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Seabuckthorn SAP label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Seabuckthorn SAP by NFH

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Seabuckthorn Fruit Oil

Interacts with
289 drugs
600 mg per serving Form: Alpha-Linolenic Acid, Linoleic Acid, Oleic Acid, Palmitoleic Acid

Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Earl...

Seabuckthorn Fruit Oil monograph & interactions

Seabuckthorn Seed Oil

Interacts with
289 drugs
400 mg per serving Form: Alpha-Linolenic Acid, Linoleic Acid, Oleic Acid

Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Earl...

Seabuckthorn Seed Oil monograph & interactions

Other (inactive) ingredients: Vitamin E, Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Seabuckthorn SAP by NFH Drug Interactions

Want to check YOUR meds against Seabuckthorn SAP?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
289Drugs
289 Moderate

Ingredients driving the most interactions

Seabuckthorn Fruit Oil 289

Individual Drug Interactions

The ingredients in Seabuckthorn SAP interact with 289 drugs. Click any drug to see the details.

1 of the 2 ingredients in Seabuckthorn SAP interact with drugs. Each result below shows which ingredient is responsible. Seabuckthorn Fruit Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Seabuckthorn SAP with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Seabuckthorn Fruit Oil2 drug types · 289 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, sea buckthorn may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that sea buckthorn fruit extracts can inhibit platelet aggregation and adhesion to collagen and fibrinogen.

Likelihood Possible Evidence B
Antihypertensive Drugs

Theoretically, taking sea buckthorn with antihypertensive drugs might increase the risk of hypotension.
Taking sea buckthorn appears to reduce blood pressure in some patients.

Likelihood Possible Evidence D
Seabuckthorn Fruit Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Seabuckthorn SAP, from the product label.

NFH

See all NFH products
Name
NFH - Nutritional Fundamentals for Health, Inc.
Street Address
351 Rue Joseph-Carrier
City
Vaudreuil
State
QC
ZipCode
J7V 5V5
Web Address
nfh.ca
Pharmacist Counseling Corner

Seabuckthorn SAP by NFH: Common Questions

Does Seabuckthorn SAP by NFH interact with any medications?
Yes. Based on its ingredients, Seabuckthorn SAP has a known interaction with 289 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Seabuckthorn SAP contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this supplement turn my skin yellow?
At normal doses, yellow skin staining is unlikely. It's been reported only at very high doses — one documented case involved 100 grams of sea buckthorn daily for 6 months. At typical supplement doses, this shouldn't happen, but it's something to know.
Does seabuckthorn actually work for burns?
The data rates it possibly effective for burns, which means some research supports it but we'd like more evidence to be sure. It's one of the better-studied uses, but it's not a guarantee.
Is it safe if I'm breastfeeding?
There isn't enough reliable safety data on supplement doses while breastfeeding. Talk with your doctor or pharmacist before taking it — they can help you weigh the risks and benefits for your situation.
Can I take this if I use aspirin?
Not without checking first. Sea buckthorn may increase your bleeding risk when combined with blood thinners and antiplatelet drugs like aspirin. Your doctor or pharmacist needs to know you're considering this supplement.
What's the difference between the fruit oil and seed oil in here?
Both come from the seabuckthorn berry and have the same documented interactions and possible benefits. The product contains both, so you're getting the full berry profile in each capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Seabuckthorn SAP is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Seabuckthorn SAP label
Go deeper

The Full Monographs Behind Seabuckthorn SAP’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sea Buckthorn

Interacts with 289 drugs

Sea buckthorn is a berry-bearing shrub rich in vitamins, carotenoids, and fatty acids that people use for skin, eye, digestive, and heart health. Early research is promising for a few uses l...

Read the full Sea Buckthorn monograph →
Sources

Sources & How We Checked

Seabuckthorn SAP's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sea Buckthorn 7 references
  1. Johansson AK, Korte H, Yang B, et al. Sea buckthorn berry oil inhibits platelet aggregation. J Nutr Biochem 2000;11:491-5.. PubMed
  2. Grad, S. C., Muresan, I., and Dumitrascu, D. L. Generalized yellow skin caused by high intake of sea buckthorn. Forsch.Komplementmed. 2012;19(3):153-156. PubMed
  3. Vlasov, V. V. [Hippophae oil in the treatment of superficial skin burns]. Vestn.Dermatol Venerol. 1970;44(6):69-72.
  4. Chang BB, Wang F Xu TY Zhang QQ He J Zhang XJ Li J. Total flavones of Hippophae rhamnoides L. for essential hypertension: a systematic review of randomized controlled trials. Chinese Journal of Evidence-Based Medicine. 2009;9(11):1207-1213. DOI
  5. Olas B, Kontek B, Szczesna M, et al. Inhibition of blood platelet adhesion by phenolics rich fraction of Hippophae rhamnoides L. fruits. J Physiol Pharmacol. 2017;68(2):223-9.
  6. Larmo P, Järvinen R, Laihia J, et al. Effects of a sea buckthorn oil spray emulsion on dry eye. Cont Lens Anterior Eye. 2019;42(4):428-433. PubMed
  7. De Seta F, Caruso S, Di Lorenzo G, Romano F, Mirandola M, Nappi RE. Efficacy and safety of a new vaginal gel for the treatment of symptoms associated with vulvovaginal atrophy in postmenopausal women: A double-blind randomized placebo-controlled study. Ma PubMed

See these in context on the Sea Buckthorn monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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