Selenase Ingredients & Drug Interactions
by Progressive Professional from Progressive Laboratories
What is this page for?
First and foremost: checking Selenase against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Selenase is a dietary supplement by Progressive Professional from Progressive Laboratories with 5 active ingredients. Its ingredients are commonly taken for thyroid health support, antioxidant support, immune support.Based on those ingredients, 633 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chlorophyll, Selenium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Selenase by Progressive Professional from Progressive Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Selenase by Progressive Professional from Progressive Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Selenase by Progressive Professional from Progressive Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Selenase contains 5 active ingredients: selenium, pea powder, chlorophyll, lentil powder, and millet flour. Selenium is a mineral that plays a role in thyroid function and acts as an antioxidant.
Chlorophyll is the green pigment from plants. Pea, lentil, and millet powders are plant-derived ingredients.
The capsule itself is filled with rice flour, gelatin, and vegetable lubricant as inactive ingredients.
Does it work?
Strong evidence
Selenium is likely effective for selenium deficiency and possibly effective for Kashin-Beck disease (a joint disorder), pre-eclampsia, and autoimmune thyroiditis. It appears ineffective for dyslipidemia (high cholesterol and triglycerides).
Chlorophyll's effectiveness is not established in the data we hold — evidence is insufficient to rate it for genital herpes, wound healing, shingles, skin cancer, or pancreatitis. We have no effectiveness information on file for pea powder, lentil powder, or millet flour.
How safe is it?
Well-documented data
Selenium is generally well tolerated at normal dietary doses up to the recommended upper limit of 400 mcg daily. However, excess selenium is toxic and can cause gastric discomfort, headache, rash, hair loss, skin problems, fatigue, nail changes, nausea, vomiting, and weight loss — and in rare cases, multi-organ failure and death.
Long-term high-dose selenium may increase risk of nerve damage and has been linked to increased risk of certain skin cancers. Headache has been reported with daily doses up to 200 mcg for up to a year.
Chlorophyll is generally well tolerated in short-term use, though thorough safety testing is limited. The main concern is photosensitization — a reaction that makes skin extra sensitive to sun.
Rare cases of pseudoporphyria (a blistering disorder) have been reported. The safety data advises against chlorophyll use during pregnancy, and breastfeeding safety is unknown — talk with your doctor or pharmacist before using it if you are pregnant or breastfeeding.
We have no safety data on file for pea powder, lentil powder, or millet flour.
Meds to double-check
Moderate interaction found
Before taking Selenase, double-check these medication types with your doctor or pharmacist: blood thinners and antiplatelet drugs (moderate risk of bleeding), immune suppressants (moderate risk of reduced effectiveness), barbiturates (moderate risk of prolonged sedation), warfarin specifically (moderate interference risk), photosensitizing drugs (moderate additive sun sensitivity), methotrexate (moderate delayed clearance), birth control pills (minor risk of raised selenium levels), and niacin (minor reduction in HDL benefit).
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Selenase may be worth considering if you have a selenium deficiency or certain thyroid or joint conditions, but it is not appropriate for everyone. If you take blood thinners, immune suppressants, barbiturates, methotrexate, or drugs that increase sun sensitivity, talk with your doctor or pharmacist before starting — the interactions could affect how your medications work or increase side effects.
Discuss this product with your own healthcare provider to make sure it is right for your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Selenase, straight from the product label.
| Brand | Progressive Professional from Progressive Laboratories |
|---|---|
| Barcode (UPC) | 351821004723 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 16, 2022 |
| DSLD ID | 263162 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Selenase by Progressive Professional from Progressive Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Selenium | 100 mcg | 143% |
| Pea powder | 100 mg | -- |
| Chlorophyll | 1 mg | -- |
| Lentil powder | 50 mg | -- |
| Millet Flour | 50 mg | -- |
Other ingredients: Rice Flour, Gelatin, Vegetable Lubricant
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Directions: One capsule daily, or more, as directed by a health care professional.
General Statements
Sold only for dispensing by a licensed health care professional.
Precautions
Not to be used by pregnant or lactating women.
Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing.
Keep out of reach of children.
Formula
The peas, lentils, and millet in this product are carefully dried to preserve their natural nutrient content.
Naturally chelated Selenium in mixed vegetable concentrate
Formulation
Progressive Laboratories manufactured this product in its 3rd party GMP-inspected facility. (Good Manufacturing Practices)
Seals/Symbols
GMP Good Manufacturing Practice Certified GMP Compliant 21 CFR 111
Brand IP Statement(s)
Progressive Professional from Progressive Laboratories
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Selenase by Progressive Professional from Progressive Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Selenase by Progressive Professional from Progressive Laboratories
These are the 5 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Selenium
Interacts with321 drugs
Selenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who...
Selenium monograph & interactionsPea powder
Chlorophyll
Interacts with337 drugs
Chlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reduc...
Chlorophyll monograph & interactionsLentil powder
Millet Flour
Other (inactive) ingredients: Rice Flour, Gelatin, Vegetable Lubricant. These complete the product’s ingredient list but are not active constituents.
Selenase by Progressive Professional from Progressive Laboratories Drug Interactions
HelloPharmacist Interaction Report
Selenase from Progressive Professional contains selenium and chlorophyll, both of which carry documented interactions with medications.
The most serious concern is selenium's moderate-severity interaction with blood thinners (anticoagulants) and antiplatelet drugs — selenium may increase bleeding risk by raising bleeding times and inhibiting platelet activity.
Read the full breakdown — every affected drug type, severity by severity
Selenium also interacts moderately with immune-suppressing drugs (it may reduce their effectiveness), barbiturates (it may prolong sedation), and warfarin specifically (it may interfere with warfarin's blood-thinning action). Minor interactions exist with birth control pills (they may raise selenium levels, though the clinical meaning is unclear) and niacin (selenium might reduce niacin's beneficial effect on HDL cholesterol).
Chlorophyll carries moderate interactions with photosensitizing drugs (those that make skin sun-sensitive) — concomitant use may worsen photosensitization — and with methotrexate, where one case report showed delayed clearance of the drug when chlorophyll was taken at the same time. We could not check pea powder, lentil powder, or millet flour for interactions.
Altogether, these interactions span 633 individual medications.
Before starting this product, check your exact medications with your doctor or pharmacist, especially if you take blood thinners, immune suppressants, barbiturates, birth control, niacin, methotrexate, or drugs that increase sun sensitivity.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Selenase?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Selenase interact with 633 drugs. Click any drug to see the details.
2 of the 5 ingredients in Selenase interact with drugs. Each result below shows which ingredient is responsible. Chlorophyll Selenium
AcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Acetylsalicylic Acid interactionAcitretinSoriatane
How Acitretin interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Acitretin interactionAdalimumabHumira
How Adalimumab interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Adalimumab-fkjp interactionAlectinib HydrochlorideAlecensa
How Alectinib Hydrochloride interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Alectinib Hydrochloride interactionAlefaceptAmevive
How Alefacept interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumImmunosuppressants Moderate
Interaction Summary
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
Read the full Selenium + Alemtuzumab interactionAlitretinoinPanretin
How Alitretinoin interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Alitretinoin interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Selenium + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amiloride, Hydrochlorothiazide interactionAminolevulinic Acid HydrochlorideAmeluz, Gleolan
How Aminolevulinic Acid Hydrochloride interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Aminolevulinic Acid Hydrochloride interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Aminophylline, Amobarbital, Ephedrine interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amitriptyline, Perphenazine interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
ChlorophyllPhotosensitizing Drugs Moderate
Interaction Summary
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Read the full Chlorophyll + Amlodipine, Celecoxib interactionAmobarbitalAmytal
How Amobarbital interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with Selenase — through 1 ingredient. Tap an ingredient for the detail:
SeleniumBarbiturates Moderate
Interaction Summary
Theoretically, selenium might prolong the sedating effects of barbiturates.
Read the full Selenium + Amobarbital, Secobarbital interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Selenase with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Chlorophyll
Methotrexate (Trexall, Others)
Theoretically, chlorophyll may reduce the clearance of methotrexate.
In one case report, a 54-year-old male developed delayed clearance of intravenous high-dose methotrexate with concomitant use of chlorophyll. When chlorophyll was stopped 2 days prior to methotrexate treatment, methotrexate clearance was unaffected.
Photosensitizing Drugs
Theoretically, concomitant use of chlorophyll with photosensitizing drugs may have additive effects.
Chlorophyll has been reported to cause photosensitization. In two case reports, pseudoporphyria developed after oral intake of chlorophyll. Theoretically, concomitant use with other photosensitizing drugs may exacerbate this effect.
Selenium
Anticoagulant/Antiplatelet Drugs
Selenium may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Clinical research suggests that taking selenium 10 mcg/kg/day can increase bleeding times by increasing prostacyclin production, which inhibits platelet activity. Other clinical research suggests that taking selenium 75 mcg daily, in combination with ascorbic acid 600 mg, alpha-tocopherol 300 mg, and beta-carotene 27 mg, reduces platelet aggregation.
Barbiturates
Theoretically, selenium might prolong the sedating effects of barbiturates.
Laboratory research suggests that selenium can inhibit the hepatic metabolism of barbiturates. Selenium seems to prolong the sedative effect of pentobarbital in animal models.
Immunosuppressants
Theoretically, selenium supplementation may reduce the effectiveness of immunosuppressant therapy.
In vitro research and preliminary clinical evidence suggests that selenium may stimulate the immune system.
Warfarin (Coumadin)
Theoretically, selenium might interfere with warfarin activity.
Animal research suggests that selenium can increase warfarin activity. Selenium might interact with warfarin by displacing it from albumin binding sites, reducing its metabolism in the liver, or by decreasing production of vitamin K-dependent clotting factors. Selenium can also prolong bleeding times in humans by increasing prostacyclin production, which inhibits platelet activity.
Contraceptive Drugs
Contraceptive drugs might increase levels of selenium, although the clinical significance of this effect is unclear.
Some research suggests that oral contraceptives increase serum selenium levels in women taking oral contraceptives; however, other research shows no change in selenium levels. It is suggested that an increase could be due to increased carrier proteins, indicating a redistribution of selenium rather than a change in total body selenium.
Niacin
Selenium might reduce the beneficial effects of niacin on high-density lipoprotein (HDL) levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as selenium, or to the combination. It also is not known whether it will occur in other patient populations.
Brand information
Manufacturer and brand details for Selenase, from the product label.
Progressive Professional from Progressive Laboratories
See all Progressive Professional from Progressive Laboratories products- Name
- Progressive Laboratories, Inc.
- City
- Irving
- State
- Texas
- ZipCode
- 75038
- Phone Number
- 1-800-527-9512
Selenase by Progressive Professional from Progressive Laboratories: Common Questions
Does Selenase by Progressive Professional from Progressive Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
How much selenium is in each capsule?
Is this safe to take at high doses?
Can I take this if I'm pregnant or breastfeeding?
Will this help me if I don't have a selenium deficiency?
What are the most common side effects?
Can this make my skin more sensitive to the sun?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Selenase is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Selenase’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Selenium
Interacts with 321 drugsSelenium is an essential trace mineral your body needs in small amounts for thyroid function, antioxidant defense, and immune health. Most people who eat a varied diet get enough, and supple...
Read the full Selenium monograph → Herb & supplement monographChlorophyll
Interacts with 337 drugsChlorophyll is the green pigment found in plants and algae, and supplements often use a stable form called chlorophyllin. It is most studied for reducing body and fecal odor and as a topical...
Read the full Chlorophyll monograph →Sources & How We Checked
Selenase's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Selenium 36 references
- Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
- Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
- Trafikowska U, Zachara BA, Wiacek M, et al. Selenium supply and glutathione peroxidase activity in breastfed Polish infants. Acta Paediatr 1996;85:1143-5. PubMed
- Duffield-Lillico AJ, Slate EH, Reid ME, et al. Selenium supplementation and secondary prevention of nonmelanoma skin cancer in a randomized trial. J Natl Cancer Inst 2003;95:1477-81.. PubMed
- Cheung MC, Zhao XQ, Chait A, et al. Antioxidant supplements block the response of HDL to simvastatin-niacin therapy in patients with coronary artery disease and low HDL. Arterioscler Thromb Vasc Biol 2001;21:1320-6. PubMed
- Schiavon R, Freeman GE, Guidi GC, et al. Selenium enhances prostacyclin production by cultured endothelial cells: possible explanation for increased bleeding times in volunteers taking selenium as a dietary supplement. Thromb Res 1984;34:389-96. PubMed
- Davila JC, Edds GT, Osuna O, Simpson CF. Modification of the effects of aflatoxin B1 and warfarin in young pigs given selenium. Am J Vet Res 1983;44:1877-83. DOI
- Heese HD, Lawrence MA, Dempster WS, Pocock F. Reference concentrations of serum selenium and manganese in healthy nulliparas. S Afr Med J 1988;73:163-5.
- Lloyd B, Lloyd RS, Clayton BE. Effect of smoking, alcohol and other factors on the selenium status of a healthy population. J Epidemiol Commun Health 1983;37:213-7. PubMed
- Capel ID, Jenner M, Williams DC, et al. The effect of prolonged oral contraceptive steroid use on erythrocyte glutathione peroxidase activity. J Steroid Biochem 1981;14:729-32. PubMed
- Contempre B, Dumont JE, Ngo B, et al. Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium. J Clin Endocrinol PubMed
- Hofbauer LC, Spitzweg C, Magerstadt RA, Heufelder AE. Selenium-induced thyroid dysfunction. Postgrad Med J 1997;73:103-4. PubMed
- Debski B, Milner JA. Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem 2004;15:548-53. PubMed
- Ishikawa M, Sasaki M, Koiwai K, et al. Inhibition of hepatic mixed-function oxidase enzymes in mice by acute and chronic treatment with selenium. J Pharmacobiodyn 1992;15:377-85. PubMed
- Lippmann SM, Klein EA, Goodman PJ, et al. Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the selenium and vitamin E cancer prevention trial (SELECT). JAMA 2009;301:39-51. DOI
- Reid SM, Middleton P, Cossich MC, Crowther CA. Interventions for clinical and subclinical hypothyroidism in pregnancy. Cochrane Database Syst Rev 2010;(7):CD007752. PubMed
- Vinceti, M., Wei, E. T., Malagoli, C., Bergomi, M., and Vivoli, G. Adverse health effects of selenium in humans. Rev.Environ.Health 2001;16(4):233-251. PubMed
- Abrams, C. K., Siram, S. M., Galsim, C., Johnson-Hamilton, H., Munford, F. L., and Mezghebe, H. Selenium deficiency in long-term total parenteral nutrition. Nutr Clin Pract 1992;7(4):175-178. PubMed
- Spiller, H. A. and Pfiefer, E. Two fatal cases of selenium toxicity. Forensic Sci Int 8-24-2007;171(1):67-72. PubMed
- Negro, R., Greco, G., Mangieri, T., Pezzarossa, A., Dazzi, D., and Hassan, H. The influence of selenium supplementation on postpartum thyroid status in pregnant women with thyroid peroxidase autoantibodies. J Clin Endocrinol.Metab 2007;92(4):1263-1268. PubMed
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Chlorophyll 5 references
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