Shepherd's Purse Herb Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Shepherd's Purse Herb against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Shepherd's Purse Herb is a dietary supplement by Mountain Meadow Herbs with 1 active ingredient. Its ingredients are commonly taken for heavy or prolonged menstrual bleeding, minor bleeding (nosebleeds, wounds), mild diuretic.Based on those ingredients, 264 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Shepherd's Purse Herb Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Shepherd's Purse Herb by Mountain Meadow Herbs
Ask about any prescription or over-the-counter medication and we check it for interactions with Shepherd's Purse Herb by Mountain Meadow Herbs — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Shepherd's Purse Herb by Mountain Meadow Herbs
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Shepherd's Purse Herb Extract, delivered in a liquid form. The extract is suspended in glycerin and distilled water.
Does it work?
Insufficient evidence
The evidence we have on Shepherd's Purse for postpartum complications and heavy menstrual bleeding (menorrhagia) is insufficient — we can't say whether it works for these uses based on the data we hold. If you're considering it for either of these reasons, talk with your pharmacist or doctor about what the research actually supports.
How safe is it?
Well-documented data
When used short-term in small amounts by adults, shepherd's purse is generally well tolerated. However, human safety data are limited, so we don't have a complete picture of how safe it is over time.
Shepherd's purse may stimulate the uterus, so do not use it during pregnancy. Avoid it while breastfeeding as well — there isn't enough safety information to know whether it passes into breast milk or could affect your baby.
Traditionally, adverse effects linked to shepherd's purse have included sedation, high or low blood pressure, abnormal thyroid function, irregular menstruation, and heart palpitations. When used in small amounts short-term, these aren't common, but they're worth knowing about.
Meds to double-check
Moderate interaction found
Check your medications if you take sedative or sleep-aid drugs — shepherd's purse may make their drowsy effects stronger. Also check if you're on thyroid hormone replacement therapy, as this herb may interfere with how well it works.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Shepherd's purse is a single-ingredient herbal extract with limited human safety data and moderate interactions with sedative drugs and thyroid medication. If you take either of those, check your exact medications before starting.
Talk with your pharmacist about whether short-term use makes sense for your situation.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Shepherd's Purse Herb, straight from the product label.
| Brand | Mountain Meadow Herbs |
|---|---|
| Barcode (UPC) | 813086017080 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 327802 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Shepherd's Purse Herb by Mountain Meadow Herbs, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Shepherd's Purse Herb Extract | 1.25 mL | -- |
Other ingredients: Glycerin, Water, Distilled
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formula
Capsella bursa pastoris
Formulation
Alcohol free
Hand-made extract
GF (Gluten free)
Vegan
Anti-inflammatory properties May lessen bleeding Supports healthy water levels
FDA Statement of Identity
Herbal Dietary Supplement
General Statements
1 dropperful = approx. 1/8 tsp.
Midwife favorite
The MMH Three Leaf Promise: Our high-standards produce nothing less than pure, safe, and effective herbal products. You will always feel that we care - through our products, our service, and our understanding. We deliver on time.
Seals/Symbols
Made in Montana USA
Suggested/Recommended/Usage/Directions
Suggested use: 1/4 tsp. Take 1-3 times daily, or as needed. See catalog for dosage information. Shake well.
Precautions
Caution: If you are pregnant, nursing, have a medical condition, or are taking a prescription, consult your health care provider before using this product.
Keep out of reach of children.
Storage
Store in a cool, dry place out of sunlight.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Shepherd's Purse Herb by Mountain Meadow Herbs label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Shepherd's Purse Herb by Mountain Meadow Herbs
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.25 Teaspoon(s) Dosage formLiquid Servings per container96 Amounts shown are per serving.
Shepherd's Purse Herb Extract
Interacts with264 drugs
Shepherd's purse is a traditional herb most often used to help slow heavy menstrual bleeding and other minor bleeding, but solid human research is ver...
Shepherd's Purse Herb Extract monograph & interactionsOther (inactive) ingredients: Glycerin, Water, Distilled. These complete the product’s ingredient list but are not active constituents.
Shepherd's Purse Herb by Mountain Meadow Herbs Drug Interactions
HelloPharmacist Interaction Report
Shepherd's Purse Herb by Mountain Meadow Herbs does interact with medications.
The most serious concern is with sedative drugs — things like sleep aids, anti-anxiety medications, and narcotic painkillers. Shepherd's purse may add to their calming effects, which could make you drowsy or impair your thinking more than the drug alone would.
Read the full breakdown — every affected drug type, severity by severity
It also has a moderate interaction with thyroid hormone replacement therapy. If you take levothyroxine or another thyroid medication, shepherd's purse may interfere with how well it works to manage your thyroid condition.
Altogether, these interactions span 264 individual medications. Because of the number of drugs affected, it's important to run your exact medications through the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Shepherd's Purse Herb?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Shepherd's Purse Herb interact with 264 drugs. Click any drug to see the details.
1 of the 1 ingredient in Shepherd's Purse Herb interact with drugs. Each result below shows which ingredient is responsible. Shepherd's Purse Herb Extract
Liotrix, T4/t3Euthroid 2
How Liotrix, T4/t3 interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractThyroid Hormone Moderate
Interaction Summary
Theoretically, concomitant use may interfere with thyroid dysfunction therapy.
Read the full Shepherd's Purse Herb Extract + Liotrix, T4/t3 interactionLithium Carbonate (prescription Drug)Eskalith, Lithium Carbonate
How Lithium Carbonate (prescription Drug) interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Lithium Carbonate (prescription Drug) interactionLofepramineFeprapax, Gamanil, Lomont, Tymelyt
How Lofepramine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Lofepramine interactionLorazepamAtivan
How Lorazepam interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Lorazepam interactionLoxapineAdasuve, Loxitane
How Loxapine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Loxapine interactionMagnesium Sulfate (prescription Drug)Bilagog, Magnesium Sulfate
How Magnesium Sulfate (prescription Drug) interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Magnesium Sulfate (prescription Drug) interactionMenotropinsMenopur, Repronex
How Menotropins interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractThyroid Hormone Moderate
Interaction Summary
Theoretically, concomitant use may interfere with thyroid dysfunction therapy.
Read the full Shepherd's Purse Herb Extract + Menotropins interactionMeperidineCytospaz, Pethadol
How Meperidine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Meperidine interactionMeperidine, PromethazineMepergan, Meprozine
How Meperidine, Promethazine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Meperidine, Promethazine interactionMephenytoinMesantoin
How Mephenytoin interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Mephenytoin interactionMephobarbitalMebaral
How Mephobarbital interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Mephobarbital interactionMeprobamateEquanil, Meprospan, Miltown, Neuramate
How Meprobamate interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Meprobamate interactionMethadoneDolophine
How Methadone interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Methadone interactionMethaqualoneQuaalude
How Methaqualone interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Methaqualone interactionMetharbitalGemonil
How Metharbital interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Metharbital interactionMethsuximideCelontin
How Methsuximide interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Methsuximide interactionMetoclopramideMetoclopramide Injection, Octamide, Reglan
How Metoclopramide interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Metoclopramide interactionMetoclopramide HydrochlorideGimoti
How Metoclopramide Hydrochloride interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Metoclopramide Hydrochloride interactionMidazolamNayzilam, Seizalam, Versed
How Midazolam interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Midazolam interactionMorphine SulfateArymo ER, Avinza, Kadian, Morphabond, MS Contin
How Morphine Sulfate interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Morphine Sulfate interactionNalbuphineNubain
How Nalbuphine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Nalbuphine interactionNaloxone, PentazocineTalwin Nx
How Naloxone, Pentazocine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Naloxone, Pentazocine interactionNaltrexone Hydrochloride, Oxycodone HydrochlorideTroxyca ER
How Naltrexone Hydrochloride, Oxycodone Hydrochloride interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Naltrexone Hydrochloride, Oxycodone Hydrochloride interactionNelarabineAtriance
How Nelarabine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Nelarabine interactionNitrazepamApo-Nitrazepam, Mogadon, Nitrazadon, Rho-Nitrazepam, Rhoxal-Nitrazepam
How Nitrazepam interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Nitrazepam interactionOpium TinctureParegoric
How Opium Tincture interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Opium Tincture interactionOspemifeneOsphena
How Ospemifene interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractThyroid Hormone Moderate
Interaction Summary
Theoretically, concomitant use may interfere with thyroid dysfunction therapy.
Read the full Shepherd's Purse Herb Extract + Ospemifene interactionOxazepamSerax
How Oxazepam interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Oxazepam interactionOxcarbazepineOxtellar XR, Trileptal
How Oxcarbazepine interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Oxcarbazepine interactionOxycodoneOxecta, OxyContin, OxyIR, OxyNeo, Percolone, Roxicodone
How Oxycodone interacts with Shepherd's Purse Herb — through 1 ingredient. Tap an ingredient for the detail:
Shepherd's Purse Herb ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Read the full Shepherd's Purse Herb Extract + Oxycodone interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Shepherd's Purse Herb with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Shepherd's Purse Herb Extract
Cns Depressants
Theoretically, concomitant use with drugs with sedative properties may cause additive effects and side effects.
Thyroid Hormone
Theoretically, concomitant use may interfere with thyroid dysfunction therapy.
Brand information
Manufacturer and brand details for Shepherd's Purse Herb, from the product label.
Mountain Meadow Herbs
See all Mountain Meadow Herbs products- Name
- Mountain Meadow Herbs, Inc.
- Street Address
- 1019 Hard Rock Rd
- City
- Somers
- State
- MT
- ZipCode
- 59932
- Phone Number
- 888.528.8615
- Web Address
- www.mmherbs.com
Shepherd's Purse Herb by Mountain Meadow Herbs: Common Questions
Does Shepherd's Purse Herb by Mountain Meadow Herbs interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm pregnant?
Is it safe to use while breastfeeding?
Does this actually work for heavy periods or postpartum bleeding?
What are the common side effects?
How long can I safely use this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Shepherd's Purse Herb is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Shepherd's Purse Herb’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Shepherd's Purse Herb's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Shepherd's Purse 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Naafe M, Kariman N, Keshavarz Z, et al. Effect of hydroalcoholic extracts of Capsella bursa-pastoris on heavy menstrual bleeding: A randomized clinical trial. J Altern Complement Med. 2018;24(7):694-700. PubMed
- Ghalandari S, Kariman N, Sheikhan Z, et al. Effect of hydroalcoholic extract of Capsella bursa pastoris on early postpartum hemorrhage: A clinical trial study. J Altern Complement Med. 2017;23(10):794-799.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC