Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

SinuCare Ingredients & Drug Interactions

by Terry Naturally

Softgel Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

SinuCare is a dietary supplement by Terry Naturally with 2 active ingredients. Its ingredients are commonly taken for cough and chest congestion, colds and flu symptoms, stuffy nose.Based on those ingredients, 878 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eucalyptus (Eucalyptus radiata) leaf oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of SinuCare by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Formula” is a proprietary blend — the label gives one combined amount (320 mg) without saying how much of each component you get.

SinuCare contains two active ingredients: eucalyptus leaf oil and myrtle leaf oil, both plant extracts traditionally used for respiratory support. The product is delivered as a softgel capsule, which also holds inactive ingredients — extra virgin olive oil, gelatin, glycerol, and water — that serve as carriers and capsule material.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: respiratory and sinus health support.
  • We looked for evidence on: Asthma, Bronchitis, Cough, Influenza, Respiratory tract infections, Rhinosinusitis — and 3 related terms.
  • The closest evidence on file: Myrtle is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Eucalyptus is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Asthma, Cough, Influenza, and more.

The evidence for eucalyptus and myrtle for respiratory conditions like bronchitis and asthma is currently insufficient to rate — we don't have reliable data on how well they work for these purposes. Eucalyptus has also been studied for acne, burns, and cancer, but again the evidence isn't established in the data we hold.

Myrtle similarly lacks solid evidence for acne, bacterial infections, respiratory tract infections, diarrhea, GERD, or gingivitis.

The evidence, ingredient by ingredient Eucalyptus Myrtle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eucalyptus leaf oil is generally well tolerated in small, diluted amounts, but the undiluted oil can be toxic if swallowed — the data cautions against internal use except under medical supervision. Common side effects from diluted oral use include diarrhea, nausea, and vomiting; topical use may cause burning, itching, redness, or stinging.

Rare but serious effects include central nervous system depression, shallow breathing, seizures, coma, and death with high doses. There's also a rare risk of allergic reactions and worsening of asthma or rhinitis symptoms in susceptible people.

Myrtle leaf oil has limited safety data overall. Topically it's generally well tolerated, though dry skin can occur.

There isn't enough information on oral or vaginal use to be confident. Rare serious effects reported orally include low blood pressure and respiratory failure.

The safety data advises against myrtle during pregnancy and breastfeeding because there isn't enough evidence to know it's safe.

Side effects, ingredient by ingredient Eucalyptus Myrtle

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Eucalyptus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 879 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking SinuCare, check with your doctor or pharmacist if you take any medications that depend on your liver's cytochrome P450 enzymes — these are Moderate-severity interactions and include many common drugs. Also flag any diabetes medications (risk of low blood sugar), amphetamines, or pentobarbital (sedative).

The eucalyptus content could theoretically raise levels of or reduce the effectiveness of these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

SinuCare may appeal to you if you're looking for plant-based respiratory support, but it's essential to check how eucalyptus interacts with any medications you take — particularly drugs your liver metabolizes. If you're pregnant or breastfeeding, the safety data advises against the myrtle content.

Talk with your doctor or pharmacist before starting this product, especially if you take diabetes medication, amphetamines, or drugs processed through your liver.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SinuCare, straight from the product label.

Brand Terry Naturally
Barcode (UPC) 367703310066
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD May 24, 2018
DSLD ID 177221
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SinuCare by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
367703310066
IngredientAmount% DV
Proprietary Formula320 mg--
Eucalyptus (Eucalyptus radiata) leaf oil0 NP--
Myrtle (Myrtus communis) leaf oil0 NP--

Other ingredients: extra virgin Olive Oil, Gelatin, Glycerol, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Money-back guarantee

These unique botanical extracts have been shown to directly provide effective respiratory system support in part by their ability to support healthy cilia activity.

The nose and sinuses are lined with complex tissues that secrete mucus, which keeps the lining hydrated and acts as a barrier by trapping inhaled particles. It is the job of the cilia to brush the mucus in a direction leading out of the sinus and nasal cavities. Healthy cilia function is required for clear and comfortable sinuses! - Goes to work immediately for results you can feel - Does not cause drowsiness or jitteriness - Supports both the sinus and bronchial airway passages SinuCare Breathe free

Plant oils are 75 to 100 times more concentrated than dry herbs.

Immediate action

Sinus, bronchial, and lung support Soothes mucous membranes Non-drowsy For your good health Terry

Product of Belgium

Brand IP Statement(s)

Why SinuCare? Immediate action!

Terry Naturally EuroPharma

Formula

SinuCare provides the soothing support of Eucalyptus and Myrtle to help you breathe easy.

Amazing ingredients! SinuCare provides Eucalyptus and Myrtle to support sinus, bronchial, lung, and entire upper respiratory function. - Refreshing Eucalyptus (Eucalyptus radiata) has long been studied and shown to support healthy, clear sinus passages. - Strong Myrtle (Myrtus communis) supports a healthy respiratory environment, and provides the key compound, 1,8 cineole for effective support!

With Eucalyptus

Formulation

Non-GMO

No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

JC 34 91 + 3(5,6)EP BX31006.05

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommendations: 1 to 2 softgels, three times daily, or as needed.

Precautions

If pregnant or nursing, consult a health care practitioner before using.

Storage

Store in a cool, dry place.

See for yourself

SinuCare by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SinuCare by Terry Naturally

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Formula

320 mg per serving

Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Glycerol, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

SinuCare by Terry Naturally Drug Interactions

Want to check YOUR meds against SinuCare?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
878Drugs
878 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in SinuCare with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Eucalyptus (Eucalyptus radiata) leaf oil7 drug types · 878 drugs

Amphetamines

Theoretically, inhaling eucalyptol may reduce the effectiveness of amphetamines.
Animal research suggests that inhaling eucalyptol may reduce the levels of amphetamines in the blood.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Animal research suggests that eucalyptus leaf might have hypoglycemic activity, and might have additive effects when used with antidiabetes drugs.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP1A2, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, eucalyptus might increase the levels of CYP2C19 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C19, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C9, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP3A4, although this has not been reported in humans.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, inhaling eucalyptol might reduce the effectiveness of pentobarbital.
Animal research suggests that inhaling eucalyptol reduces the level of pentobarbital that reaches the brain.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for SinuCare, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
EuroPharmaUSA.com
Pharmacist Counseling Corner

SinuCare by Terry Naturally: Common Questions

Does SinuCare by Terry Naturally interact with any medications?
Yes. Based on its ingredients, SinuCare has a known interaction with 878 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SinuCare contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is eucalyptus oil in SinuCare safe to take by mouth?
The data cautions against taking undiluted eucalyptus oil internally — it can be toxic at doses as low as 1 mL, causing serious effects like shallow breathing, seizures, and coma. Diluted oral eucalyptus is generally better tolerated, but you should check with your doctor before taking it internally and never take the concentrated oil.
Can I take SinuCare if I'm pregnant or breastfeeding?
Eucalyptus is rated likely safe in pregnancy and lactation, but myrtle is rated likely unsafe during both — the safety data advises against it. Because this product contains myrtle, talk with your doctor or pharmacist about whether it's right for you if you're pregnant or nursing.
What are the most common side effects?
If taken orally, diluted eucalyptus commonly causes diarrhea, nausea, and vomiting. If applied to the skin, it may cause burning, itching, redness, or stinging. Myrtle applied topically may cause dry skin.
Does SinuCare have fillers or other inactive ingredients?
Yes — the softgel capsule also contains extra virgin olive oil, gelatin, glycerol, and water as inactive ingredients that support the delivery of the active oils.
Has eucalyptus been proven to work for bronchitis or asthma?
The reliable evidence for eucalyptus to treat bronchitis, asthma, or other respiratory conditions isn't established in the data we hold. The rating is insufficient to say whether it works for these purposes.
Is there any risk of an allergic reaction?
Yes — although rare, a case of allergic reaction with worsening asthma and rhinitis symptoms has been reported in someone who consumed eucalyptus. If you have a history of allergies or asthma, discuss this with your doctor before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SinuCare is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SinuCare label
Sources

Sources & How We Checked

SinuCare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eucalyptus 23 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
  3. De Vincenzi M, Silano M, De Vincenzi A, et al. Constituents of aromatic plants: eucalyptol. Fitoterapia 2002;73:269-75. PubMed
  4. Gray AM, Flatt PR. Antihyperglycemic actions of Eucalyptus globulus (Eucalyptus) are associated with pancreatic and extra-pancreatic effects in mice. J Nutr 1998;128:2319-23. PubMed
  5. Whitman BW, Ghazizadeh H. Eucalyptus oil: therapeutic and toxic aspects of pharmacology in humans and animals. J Paediatr Child Health 1994;30:190-1. PubMed
  6. Barker SC and Altman PM. An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application--melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil,
  7. Vilaplana, J. and Romaguera, C. Allergic contact dermatitis due to eucalyptol in an anti-inflammatory cream. Contact Dermatitis 2000;43(2):118.
  8. Juergens, U. R. [Reducing the need for cortisone. Does eucalyptus oil work in asthma? (interview by Brigitte Moreano]. MMW.Fortschr Med 3-29-2001;143(13):14.
  9. Tascini, C., Ferranti, S., Gemignani, G., Messina, F., and Menichetti, F. Clinical microbiological case: fever and headache in a heavy consumer of eucalyptus extract. Clin Microbiol.Infect. 2002;8(7):437, 445-437, 446. PubMed
  10. Galdi, E., Perfetti, L., Calcagno, G., Marcotulli, M. C., and Moscato, G. Exacerbation of asthma related to Eucalyptus pollens and to herb infusion containing Eucalyptus. Monaldi Arch.Chest Dis. 2003;59(3):220-221.
  11. Spoerke, D. G., Vandenberg, S. A., Smolinske, S. C., Kulig, K., and Rumack, B. H. Eucalyptus oil: 14 cases of exposure. Vet Hum.Toxicol 1989;31(2):166-168.
  12. Jori, A., Bianchetti, A., Prestini, P. E., and Gerattini, S. Effect of eucalyptol (1,8-cineole) on the metabolism of other drugs in rats and in man. Eur.J Pharmacol 1970;9(3):362-366. PubMed
  13. Tibballs, J. Clinical effects and management of eucalyptus oil ingestion in infants and young children. Med J Aust 8-21-1995;163(4):177-180. PubMed
  14. Webb, N. J. and Pitt, W. R. Eucalyptus oil poisoning in childhood: 41 cases in south-east Queensland. J Paediatr.Child Health 1993;29(5):368-371. PubMed
  15. Gyldenløve M, Menné T, Thyssen JP. Eucalyptus contact allergy. Contact Dermatitis. 2014;71(5):303-304. PubMed
  16. Higgins C, Palmer A, Nixon R. Eucalyptus oil: contact allergy and safety. Contact Dermatitis. 2015;72(5):344-346. PubMed
  17. de Groot AC, Schmidt E. Eucalyptus oil and tea tree oil. Contact Dermatitis. 2015;73(6):381-386. PubMed
  18. Greive KA, Barnes TM. The efficacy of Australian essential oils for the treatment of head lice infestation in children: A randomised controlled trial. Australas J Dermatol. 2018;59(2):e99-e105. PubMed
  19. Paulsen E, Thormann H, Vestergaard L. Eucalyptus species as a cause of airborne allergic contact dermatitis. Contact Dermatitis. 2018;78(4):301-303.
  20. Mathew T, John SK, Kamath V, et al. Essential oil related seizures (EORS): A multi-center prospective study on essential oils and seizures in adults. Epilepsy Res. 2021;173:106626. PubMed
  21. Dudipala SC, Mandapuram P, Ch LK. Eucalyptus Oil-Induced Seizures in Children: Case Reports and Review of the Literature. J Neurosci Rural Pract 2021;12(1):112-115. PubMed
  22. Panda PK, Sharawat IK, Panda P, Dawman L, Kasinathan A. Clinico-laboratory characteristics and outcome of patients with eucalyptus oil-induced/provoked seizures: A case series and systematic review of the published patients. Trop Doct 2021;51(4):518-522. PubMed
  23. Sai Chandar D, Prashanthi M, Laxman Kumar C, Amith Kumar C. Eucalyptus Oil-Induced Seizures in Children: A Single-Center Prospective Study. Cureus 2021;13(3):e14109. PubMed

See these in context on the Eucalyptus monograph →

Myrtle 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Salmanian M, Shirbeigi L, Hashem-Dabaghian F, et al. The Effects of Myrtle (Myrtus communis) and Clindamycin Topical Solution in the Treatment of Mild to Moderate Acne Vulgaris: A Comparative Split-Face Study. J Pharmacopuncture 2020;23(4):220-229.
  3. Paknejad MS, Eftekhari K, Rahimi R, Vigeh M, Naghizadeh A, Karimi M. Myrtle (Myrtus communis L.) fruit syrup for gastroesophageal reflux disease in children: A double-blind randomized clinical trial. Phytother Res 2021;35(11):6369-6376.

See these in context on the Myrtle monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring