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Dietary supplement

SinuCare Ingredients & Drug Interactions

by Terry Naturally

Softgel Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

SinuCare is a dietary supplement by Terry Naturally with 2 active ingredients. Its ingredients are commonly taken for cough and chest congestion, colds and flu symptoms, stuffy nose.Based on those ingredients, 878 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eucalyptus (Eucalyptus radiata) leaf oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of SinuCare by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Formula” is a proprietary blend — the label gives one combined amount (320 mg) without saying how much of each component you get.

SinuCare has 2 active ingredients: eucalyptus leaf oil and myrtle leaf oil. Eucalyptus is a traditional respiratory ingredient, though the evidence backing its specific uses — acne, bronchitis, asthma, burns, and cancer — is insufficient in the data we hold.

Myrtle leaf oil is included for similar purposes, but again, the evidence for acne, bacterial vaginosis, respiratory tract infections, diarrhea, GERD, and gingivitis is not established. The product is rounded out with inactive ingredients: extra virgin olive oil, gelatin, glycerol, and water.

These are standard excipients that give the softgel its form and help your body absorb the oils.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: sinus and respiratory system support.
  • We looked for evidence on: Rhinosinusitis, Bronchitis, Cough, Respiratory tract infections, Influenza, nasal congestion — and 3 related terms.
  • The closest evidence on file: Myrtle is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Eucalyptus is rated "Insufficient Reliable Evidence To Rate" for Bronchitis, Cough, Influenza, Rhinosinusitis.

The evidence for eucalyptus in this product doesn't reach reliable strength for any of its listed uses — acne, bronchitis, asthma, burns, and cancer all show insufficient reliable evidence to rate in our data. The same goes for myrtle: acne, bacterial vaginosis, respiratory tract infections, diarrhea, GERD, and gingivitis all have insufficient evidence.

If you're considering SinuCare for a specific condition, we'd recommend talking with your doctor or pharmacist about whether the science backs it for what you're after.

The evidence, ingredient by ingredient Eucalyptus Myrtle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Eucalyptus is generally well tolerated when used in small amounts for inhalation or diluted topical application, but the undiluted oil can cause serious harm if swallowed — toxicity can occur at doses as low as 1 mL and includes nervous system depression, shallow breathing, and in rare cases, seizures or death. The most common side effects from diluted oral use are diarrhea, nausea, and vomiting; topically, you might see burning, itching, redness, or stinging.

A handful of people have reported that eucalyptus worsened asthma and hay fever symptoms, and occupational exposure can cause allergic skin reactions. Myrtle leaf oil has limited safety data.

Topically it's generally well tolerated, though dry skin can happen. Orally and intravaginally, information is sparse — but rare serious effects like low blood pressure and respiratory failure have been reported with very large undiluted amounts.

During pregnancy, myrtle is rated likely unsafe, and safety while breastfeeding is unknown, so both should be avoided. Eucalyptus is rated likely safe in pregnancy and lactation.

Side effects, ingredient by ingredient Eucalyptus Myrtle

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Eucalyptus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 879 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medication metabolized by CYP1A2, CYP2C19, CYP2C9, or CYP3A4 enzymes — that's a long list covering everything from blood thinners to statins to many antidepressants — check with your pharmacist. Also double-check if you use diabetes medications, amphetamine-based stimulants, or the sedative pentobarbital before starting this product.

No interactions are documented for the myrtle leaf oil we hold data on.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

SinuCare is built around essential oils with a long history in traditional medicine, but the science supporting their specific uses isn't strong yet. If you take diabetes medications, stimulants, sedatives, or drugs processed by your liver, check with your pharmacist first — eucalyptus can theoretically raise their blood levels or reduce how well they work.

Pregnant or breastfeeding? Talk to your doctor, especially about the myrtle.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about SinuCare, straight from the product label.

Brand Terry Naturally
Barcode (UPC) 367703310066
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD May 24, 2018
DSLD ID 177221
Product type Botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for SinuCare by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
30
UPC/BARCODE
367703310066
IngredientAmount% DV
Proprietary Formula320 mg--
Eucalyptus (Eucalyptus radiata) leaf oil0 NP--
Myrtle (Myrtus communis) leaf oil0 NP--

Other ingredients: extra virgin Olive Oil, Gelatin, Glycerol, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Money-back guarantee

These unique botanical extracts have been shown to directly provide effective respiratory system support in part by their ability to support healthy cilia activity.

The nose and sinuses are lined with complex tissues that secrete mucus, which keeps the lining hydrated and acts as a barrier by trapping inhaled particles. It is the job of the cilia to brush the mucus in a direction leading out of the sinus and nasal cavities. Healthy cilia function is required for clear and comfortable sinuses! - Goes to work immediately for results you can feel - Does not cause drowsiness or jitteriness - Supports both the sinus and bronchial airway passages SinuCare Breathe free

Plant oils are 75 to 100 times more concentrated than dry herbs.

Immediate action

Sinus, bronchial, and lung support Soothes mucous membranes Non-drowsy For your good health Terry

Product of Belgium

Brand IP Statement(s)

Why SinuCare? Immediate action!

Terry Naturally EuroPharma

Formula

SinuCare provides the soothing support of Eucalyptus and Myrtle to help you breathe easy.

Amazing ingredients! SinuCare provides Eucalyptus and Myrtle to support sinus, bronchial, lung, and entire upper respiratory function. - Refreshing Eucalyptus (Eucalyptus radiata) has long been studied and shown to support healthy, clear sinus passages. - Strong Myrtle (Myrtus communis) supports a healthy respiratory environment, and provides the key compound, 1,8 cineole for effective support!

With Eucalyptus

Formulation

Non-GMO

No sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

JC 34 91 + 3(5,6)EP BX31006.05

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommendations: 1 to 2 softgels, three times daily, or as needed.

Precautions

If pregnant or nursing, consult a health care practitioner before using.

Storage

Store in a cool, dry place.

See for yourself

SinuCare by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in SinuCare by Terry Naturally

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Formula

320 mg per serving

Other (inactive) ingredients: Extra virgin Olive Oil, Gelatin, Glycerol, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

SinuCare by Terry Naturally Drug Interactions

Want to check YOUR meds against SinuCare?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
878Drugs
878 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in SinuCare with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Eucalyptus (Eucalyptus radiata) leaf oil7 drug types · 878 drugs

Amphetamines

Theoretically, inhaling eucalyptol may reduce the effectiveness of amphetamines.
Animal research suggests that inhaling eucalyptol may reduce the levels of amphetamines in the blood.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, eucalyptus leaf might increase the risk of hypoglycemia.
Animal research suggests that eucalyptus leaf might have hypoglycemic activity, and might have additive effects when used with antidiabetes drugs.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, eucalyptus might increase the levels of CYP1A2 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP1A2, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, eucalyptus might increase the levels of CYP2C19 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C19, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, eucalyptus might increase the levels of CYP2C9 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP2C9, although this has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, eucalyptus might increase the levels of CYP3A4 substrates.
In vitro research suggests that eucalyptus oil might inhibit CYP3A4, although this has not been reported in humans.

Likelihood Possible Evidence D
Pentobarbital (Nembutal)

Theoretically, inhaling eucalyptol might reduce the effectiveness of pentobarbital.
Animal research suggests that inhaling eucalyptol reduces the level of pentobarbital that reaches the brain.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for SinuCare, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
EuroPharmaUSA.com
Pharmacist Counseling Corner

SinuCare by Terry Naturally: Common Questions

Does SinuCare by Terry Naturally interact with any medications?
Yes. Based on its ingredients, SinuCare has a known interaction with 878 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
SinuCare contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is eucalyptus safe to swallow in this supplement form?
The undiluted oil can be toxic if swallowed at very low doses. This product should be diluted, but check the label for dilution and the dose — and if you have any doubt, ask your pharmacist or doctor before taking it. Stick to inhalation or diluted topical use if you're nervous.
Can I use this if I'm pregnant or nursing?
Eucalyptus is rated likely safe during pregnancy and lactation, but myrtle is rated likely unsafe in pregnancy and unknown while breastfeeding. Since this product has both, talk with your doctor or pharmacist before starting — you need personalized advice for your situation.
Does this actually work for sinus issues?
The evidence backing eucalyptus and myrtle for bronchitis, asthma, and respiratory tract infections is insufficient in our data — there's not enough reliable research to say. Your doctor or pharmacist can tell you what the broader clinical picture looks like.
What side effects might I notice?
From diluted eucalyptus, the most common are diarrhea, nausea, and vomiting if taken by mouth, or burning, itching, and redness if used on skin. Serious side effects like seizures are rare but possible, especially with undiluted oil. Myrtle has limited safety data, but dry skin is common topically.
Will this interfere with my diabetes medication?
Yes — eucalyptus theoretically raises the risk of low blood sugar when combined with diabetes drugs. Check with your pharmacist or doctor before starting, especially if you're already at risk for dips in blood sugar.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if SinuCare is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

SinuCare label
Sources

Sources & How We Checked

SinuCare's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eucalyptus 23 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Unger M, Frank A. Simultaneous determination of the inhibitory potency of herbal extracts on the activity of six major cytochrome P450 enzymes using liquid chromatography/mass spectrometry and automated online extraction. Rapid Commun Mass Spectrom 2004;1 PubMed
  3. De Vincenzi M, Silano M, De Vincenzi A, et al. Constituents of aromatic plants: eucalyptol. Fitoterapia 2002;73:269-75. PubMed
  4. Gray AM, Flatt PR. Antihyperglycemic actions of Eucalyptus globulus (Eucalyptus) are associated with pancreatic and extra-pancreatic effects in mice. J Nutr 1998;128:2319-23. PubMed
  5. Whitman BW, Ghazizadeh H. Eucalyptus oil: therapeutic and toxic aspects of pharmacology in humans and animals. J Paediatr Child Health 1994;30:190-1. PubMed
  6. Barker SC and Altman PM. An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application--melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil,
  7. Vilaplana, J. and Romaguera, C. Allergic contact dermatitis due to eucalyptol in an anti-inflammatory cream. Contact Dermatitis 2000;43(2):118.
  8. Juergens, U. R. [Reducing the need for cortisone. Does eucalyptus oil work in asthma? (interview by Brigitte Moreano]. MMW.Fortschr Med 3-29-2001;143(13):14.
  9. Tascini, C., Ferranti, S., Gemignani, G., Messina, F., and Menichetti, F. Clinical microbiological case: fever and headache in a heavy consumer of eucalyptus extract. Clin Microbiol.Infect. 2002;8(7):437, 445-437, 446. PubMed
  10. Galdi, E., Perfetti, L., Calcagno, G., Marcotulli, M. C., and Moscato, G. Exacerbation of asthma related to Eucalyptus pollens and to herb infusion containing Eucalyptus. Monaldi Arch.Chest Dis. 2003;59(3):220-221.
  11. Spoerke, D. G., Vandenberg, S. A., Smolinske, S. C., Kulig, K., and Rumack, B. H. Eucalyptus oil: 14 cases of exposure. Vet Hum.Toxicol 1989;31(2):166-168.
  12. Jori, A., Bianchetti, A., Prestini, P. E., and Gerattini, S. Effect of eucalyptol (1,8-cineole) on the metabolism of other drugs in rats and in man. Eur.J Pharmacol 1970;9(3):362-366. PubMed
  13. Tibballs, J. Clinical effects and management of eucalyptus oil ingestion in infants and young children. Med J Aust 8-21-1995;163(4):177-180. PubMed
  14. Webb, N. J. and Pitt, W. R. Eucalyptus oil poisoning in childhood: 41 cases in south-east Queensland. J Paediatr.Child Health 1993;29(5):368-371. PubMed
  15. Gyldenløve M, Menné T, Thyssen JP. Eucalyptus contact allergy. Contact Dermatitis. 2014;71(5):303-304. PubMed
  16. Higgins C, Palmer A, Nixon R. Eucalyptus oil: contact allergy and safety. Contact Dermatitis. 2015;72(5):344-346. PubMed
  17. de Groot AC, Schmidt E. Eucalyptus oil and tea tree oil. Contact Dermatitis. 2015;73(6):381-386. PubMed
  18. Greive KA, Barnes TM. The efficacy of Australian essential oils for the treatment of head lice infestation in children: A randomised controlled trial. Australas J Dermatol. 2018;59(2):e99-e105. PubMed
  19. Paulsen E, Thormann H, Vestergaard L. Eucalyptus species as a cause of airborne allergic contact dermatitis. Contact Dermatitis. 2018;78(4):301-303.
  20. Mathew T, John SK, Kamath V, et al. Essential oil related seizures (EORS): A multi-center prospective study on essential oils and seizures in adults. Epilepsy Res. 2021;173:106626. PubMed
  21. Dudipala SC, Mandapuram P, Ch LK. Eucalyptus Oil-Induced Seizures in Children: Case Reports and Review of the Literature. J Neurosci Rural Pract 2021;12(1):112-115. PubMed
  22. Panda PK, Sharawat IK, Panda P, Dawman L, Kasinathan A. Clinico-laboratory characteristics and outcome of patients with eucalyptus oil-induced/provoked seizures: A case series and systematic review of the published patients. Trop Doct 2021;51(4):518-522. PubMed
  23. Sai Chandar D, Prashanthi M, Laxman Kumar C, Amith Kumar C. Eucalyptus Oil-Induced Seizures in Children: A Single-Center Prospective Study. Cureus 2021;13(3):e14109. PubMed

See these in context on the Eucalyptus monograph →

Myrtle 3 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Salmanian M, Shirbeigi L, Hashem-Dabaghian F, et al. The Effects of Myrtle (Myrtus communis) and Clindamycin Topical Solution in the Treatment of Mild to Moderate Acne Vulgaris: A Comparative Split-Face Study. J Pharmacopuncture 2020;23(4):220-229.
  3. Paknejad MS, Eftekhari K, Rahimi R, Vigeh M, Naghizadeh A, Karimi M. Myrtle (Myrtus communis L.) fruit syrup for gastroesophageal reflux disease in children: A double-blind randomized clinical trial. Phytother Res 2021;35(11):6369-6376.

See these in context on the Myrtle monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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