Stars 'N Pipes Zero Dark Cherry Ingredients & Drug Interactions
by 'Merica Labz
What is this page for?
First and foremost: checking Stars 'N Pipes Zero Dark Cherry against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Stars 'N Pipes Zero Dark Cherry is a dietary supplement by 'Merica Labz with 4 active ingredients. Its ingredients are commonly taken for exercise performance, muscle soreness and fatigue, blood flow and circulation.Based on those ingredients, 500 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pine Bark Extract, L-Citrulline. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Stars 'N Pipes Zero Dark Cherry by 'Merica Labz
Ask about any prescription or over-the-counter medication and we check it for interactions with Stars 'N Pipes Zero Dark Cherry by 'Merica Labz — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Stars 'N Pipes Zero Dark Cherry by 'Merica Labz
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This powder has 4 active ingredients. L-citrulline is an amino acid that your body converts to another amino acid, L-arginine, which helps widen blood vessels and improve blood flow — it's used to support athletic performance.
Pine Bark Extract, Nitrosigine, and HydroPrime (glycerol) round out the formula, though we hold limited interaction data for the last three. The inactive ingredients are fillers and flavoring agents to make the powder taste like dark cherry.
Does it work?
Moderate evidence
L-citrulline is possibly effective for athletic performance. The evidence isn't strong enough yet to rate it for heart disease, heart failure, diabetes, or other conditions listed.
For the other three active ingredients, the effectiveness data we hold shows mixed or insufficient evidence — glycerol (HydroPrime) is likely effective for constipation and possibly effective for athletic performance, but we have no established effectiveness ratings for Pine Bark Extract or Nitrosigine in our data.
How safe is it?
Well-documented data
L-citrulline is generally well tolerated in healthy adults, though long-term safety hasn't been fully studied. The most common side effects are gastrointestinal — heartburn and stomach discomfort — and a small number of people reported cough.
Glycerol is also generally well tolerated in normal amounts, but large doses can cause bloating, diarrhea, nausea, dizziness, and headache. There isn't enough safety data to use L-citrulline during pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized advice on this.
Meds to double-check
Moderate interaction found
Before you start, double-check any blood pressure medications you take — L-citrulline may lower blood pressure further. Also check if you're on erectile dysfunction drugs like sildenafil or tadalafil, which could have additive effects with this product.
We couldn't check the other three ingredients for drug interactions, so your pharmacist should verify your full medication list.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a pre-workout powder aimed at athletic performance. If you take blood pressure medication or erectile dysfunction medication, check your exact prescriptions with the tool on this page before starting.
L-citrulline is generally well tolerated, but stomach upset can happen. Talk to your pharmacist if you're pregnant, breastfeeding, or on any prescription medications.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Stars 'N Pipes Zero Dark Cherry, straight from the product label.
| Brand | 'Merica Labz |
|---|---|
| Barcode (UPC) | 658580071134 |
| Net contents | 12.3 Ounce(s); 350 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2024 |
| DSLD ID | 316621 |
| Product type | Other Combinations |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Stars 'N Pipes Zero Dark Cherry by 'Merica Labz, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| L-Citrulline | 6000 mg | -- |
| Pine Bark Extract | 250 mg | -- |
| Nitrosigine | 1500 mg | -- |
| HydroPrime | 5000 mg | -- |
Other ingredients: Silicon Dioxide, Citric Acid, Natural & Artificial Flavors, Malic Acid, Sucralose, Acesulfame Potassium
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Few things scream 'Merica - or freedom - like crushing a workout while wearing a pair of American flag sweatpants and a bald eagle bandana. Considering that's your everyday workout attire, that essentially makes you a freedom fighter, son. And freedom fighters can't contribute to the fight for freedom with a couple of puny small arms - they need the KABOOM! Big munitions. Well, freedom fighter, meet your best weapon in the fight against skinny arms: Stars 'N Pipes, a stim-free explosive pump agent fit for a real 'Merican hero. Stars 'N Pipes is like mixing a couple hundred lbs of TNT with Bruce Willis from Die Hard, throwing some fruit in there, and putting it all in a powder. Yeah...it's that good.
Precautions
Warning: This product is only intended for use in healthy adults 18 years of age or older.
Pregnant or nursing women should not use this product. Consult your healthcare provider before using this product, especially if you are taking any prescription, over the counter medication, dietary supplement product, or if you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver, kidney or thyroid disease, seizure disorder, psychiatric disease, diabetes, difficulty urinating due to prostate enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.
Immediately discontinue use and consult your health care professional if you experience adverse reaction to this product. Do not exceed recommended serving. Do not use if safety seal is broken or missing.
Keep out of reach of children.
Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer. For more information, go to www.P65warnings.gov.
Suggested/Recommended/Usage/Directions
Directions: Mix 1 scoop with 10-16 ounces of water and consume approximately 15-30 minutes prior to your workout.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Formulation
High Explosive Pump Agent
Manufactured in a U.S. cGMP Facility
Well, freedom fighter, meet your best weapon in the fight against skinny arms: Stars 'N Pipes, a stim-free explosive pump agent fit for a real 'Merican hero.
FDA Statement of Identity
Dietary Supplement
Formula
Zero Dark Cherry Naturally & Artificially Flavored HydroPrime Nitrosigine
Stars 'N Pipes is like mixing a couple hundred lbs of TNT with Bruce Willis from Die Hard, throwing some fruit in there, and putting it all in a powder. Yeah...it's that good.
Brand IP Statement(s)
HydroPrime is a trademark of NNB Nutrition The Nitrosigine name and logo are registered trademarks of Nutrition 21, LLC. Nitrosigine is patent protected.
'Merica Labz Never Big Enough
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Stars 'N Pipes Zero Dark Cherry by 'Merica Labz label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Stars 'N Pipes Zero Dark Cherry by 'Merica Labz
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size17.5 Gram(s) Dosage formPowder Servings per container20 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Citrulline
Interacts with178 drugs
L-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. I...
L-Citrulline monograph & interactionsPine Bark Extract
Interacts with327 drugs
Maritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research...
Pine Bark Extract monograph & interactionsNitrosigine
HydroPrime
No knowninteractions
Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well establis...
HydroPrime monograph & interactionsOther (inactive) ingredients: Silicon Dioxide, Citric Acid, Natural & Artificial Flavors, Malic Acid, Sucralose, Acesulfame Potassium. These complete the product’s ingredient list but are not active constituents.
Stars 'N Pipes Zero Dark Cherry by 'Merica Labz Drug Interactions
HelloPharmacist Interaction Report
'Merica Labz Stars 'N Pipes Zero Dark Cherry contains L-citrulline, which does interact with some medications.
The main concern is with blood pressure drugs (antihypertensive medications). L-citrulline widens blood vessels, so taking it alongside blood pressure medication may lower your pressure more than either does alone — a Moderate severity interaction.
Read the full breakdown — every affected drug type, severity by severity
It also interacts with erectile dysfunction medications like sildenafil (Viagra) and tadalafil (Cialis) at Moderate severity. These drugs work by relaxing blood vessels too, so combined with L-citrulline, the effect could be stronger and potentially drop your blood pressure more than expected.
We couldn't check Pine Bark Extract, Nitrosigine, or HydroPrime (glycerol) for drug interactions — we hold no interaction data for them. Altogether, these interactions span 176 individual medications.
Use the medication checker below to see if any of your prescriptions are on that list.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Stars 'N Pipes Zero Dark Cherry?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Stars 'N Pipes Zero Dark Cherry interact with 500 drugs. Click any drug to see the details.
2 of the 4 ingredients in Stars 'N Pipes Zero Dark Cherry interact with drugs. Each result below shows which ingredient is responsible. Pine Bark Extract L-Citrulline
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + 6-mercaptopurine interactionAbciximabReoPro
How Abciximab interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs, Immunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Acetylsalicylic Acid interactionAdalimumabHumira
How Adalimumab interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab interactionAdalimumab-adazHyrimoz
How Adalimumab-adaz interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-adaz interactionAdalimumab-adbmCyltezo
How Adalimumab-adbm interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-adbm interactionAdalimumab-afzbAbrilada
How Adalimumab-afzb interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-afzb interactionAdalimumab-attoAmjevita
How Adalimumab-atto interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-atto interactionAdalimumab-bwwdHadlima
How Adalimumab-bwwd interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-bwwd interactionAdalimumab-fkjpHulio
How Adalimumab-fkjp interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Adalimumab-fkjp interactionAlbiglutideTanzeum
How Albiglutide interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Albiglutide interactionAlefaceptAmevive
How Alefacept interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Alefacept interactionAlemtuzumabCampath
How Alemtuzumab interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
Read the full Pine Bark Extract + Alemtuzumab interactionAliskirenTekturna
How Aliskiren interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
Read the full Pine Bark Extract + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
Pine Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Pine Bark Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Stars 'N Pipes Zero Dark Cherry — through 1 ingredient. Tap an ingredient for the detail:
L-citrullineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
Read the full L-citrulline + Ambrisentan interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Stars 'N Pipes Zero Dark Cherry with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Pine Bark Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, maritime pine bark extract might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Clinical research suggests that maritime pine bark extract inhibits platelet aggregation. However, the clinical significance of this effect is unclear.
Antidiabetes Drugs
Theoretically, maritime pine bark extract might increase the risk of hypoglycemia when used with antidiabetes drugs.
One clinical study shows that maritime pine bark extract decreases blood sugar in patients with diabetes being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Immunosuppressants
Theoretically, maritime pine bark extract might decrease the effectiveness of immunosuppressant therapy.
In vitro and animal research suggests that maritime pine bark extract has immunostimulant activity. This effect has not been reported in humans.
L-Citrulline
Antihypertensive Drugs
Theoretically, concomitant use of L-citrulline with antihypertensive drugs might have additive effects and increase the chance of hypotension.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. However, a meta-analysis of 5 small clinical studies suggests that taking L-citrulline 3-6 grams daily for 1-8 weeks does not lower blood pressure when compared with control.
Phosphodiesterase-5 Inhibitors
Theoretically, concurrent use of phosphodiesterase-5 (PDE-5) inhibitors and L-citrulline might result in additive vasodilation.
L-citrulline is converted to L-arginine, which can increase nitric oxide and cause vasodilation. Theoretically, taking L-arginine with PDE-5 inhibitors might have additive vasodilatory and hypotensive effects. However, in studies evaluating the combined use of L-arginine and sildenafil for erectile dysfunction, hypotension was not reported.
Brand information
Manufacturer and brand details for Stars 'N Pipes Zero Dark Cherry, from the product label.
'Merica Labz
- Name
- 'Merica Labz, LLC.
- City
- Statesville
- State
- NC
- ZipCode
- 28625
- Phone Number
- 844-445-5335
- Web Address
- www.MericaLabz.com
Stars 'N Pipes Zero Dark Cherry by 'Merica Labz: Common Questions
Does Stars 'N Pipes Zero Dark Cherry by 'Merica Labz interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Does L-citrulline actually improve athletic performance?
What are the most common side effects?
Is it safe to use while pregnant or breastfeeding?
What's the difference between L-citrulline and L-arginine?
What is glycerol (HydroPrime) doing in a pre-workout?
Can I use this if I take Viagra or Cialis?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Stars 'N Pipes Zero Dark Cherry is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Stars 'N Pipes Zero Dark Cherry’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
L-citrulline
Interacts with 178 drugsL-citrulline is an amino acid that the body turns into L-arginine to help make nitric oxide, which relaxes blood vessels and may improve blood flow. It is popular for exercise performance an...
Read the full L-citrulline monograph → Herb & supplement monographMaritime Pine
Interacts with 327 drugsMaritime pine bark extract (often sold as Pycnogenol) is a plant-based antioxidant most studied for circulation, vein, and skin health. Some research is promising, but many studies are small...
Read the full Maritime Pine monograph → Herb & supplement monographGlycerol
Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...
Read the full Glycerol monograph →Sources & How We Checked
Stars 'N Pipes Zero Dark Cherry's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 30 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
L-citrulline 8 references
- Cheng JW, Balwin SN. L-arginine in the management of cardiovascular diseases. Ann Pharmacother 2001;35:755-64. PubMed
- Schwedhelm E, Maas R, Freese R, et al. Pharmacokinetic and pharmacodynamic properties of oral L-citrulline and L-arginine: impact on nitric oxide metabolism. Br J Clin Pharmacol 2008;65:51-9. PubMed
- Romero MJ, Platt DH, Caldwell RB, Caldwell RW. Therapeutic use of citrulline in cardiovascular disease. Cardiovasc Drug Rev 2006;24:275-90. PubMed
- Balderas-Munoz K, Castillo-Martínez L, Orea-Tejeda A, et al. Improvement of ventricular function in systolic heart failure patients with oral L-citrulline supplementation. Cardiol J 2012;19:612-7. PubMed
- Sharif Kashani B, Tahmaseb Pour P, Malekmohammad M, et al. Oral l-citrulline malate in patients with idiopathic pulmonary arterial hypertension and Eisenmenger Syndrome: a clinical trial. J Cardiol 2014;64:231-5. PubMed
- Pérez-Guisado J, Jakeman PM. Citrulline malate enhances athletic anaerobic performance and relieves muscle soreness. J Strength Cond Res 2010;24:1215-22. PubMed
- Mirenayat MS, Moradi S, Mohammadi H, Rouhani MH. Effect of L-citrulline supplementation on blood pressure: a systematic review and meta-analysis of clinical trials. Curr Hypertens Rep. 2018;20(11):98. PubMed
- Xu Z, Liu C, Liu S, Zhou Z. Comparison of efficacy and safety of daily oral L-arginine and PDE5Is alone or combination in treating erectile dysfunction: A systematic review and meta-analysis of randomised controlled trials. Andrologia. 2021:e14007. PubMed
Maritime Pine 14 references
- Rice-Evans CA, Packer L, eds. Flavonoids in Health and Disease. Manhattan, NY: Marcel Dekker, Inc., 1998.
- Liu FJ, Zhang YX, Lau BH. Pycnogenol enhances immune and haemopoietic functions in senescence-accelerated mice. Cell Mol Life Sci 1998;54:1168-72. PubMed
- Putter M, Grotemeyer KH, Wurthwein G, et al. Inhibition of smoking-induced platelet aggregation by aspirin and pycnogenol. Thromb Res 1999;95:155-61. PubMed
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