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Dietary supplement

Stronium Bone Power Ingredients & Drug Interactions

by Highland Laboratories

Capsule Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Stronium Bone Power is a dietary supplement by Highland Laboratories with 1 active ingredient. Its ingredients are commonly taken for bone health and osteoporosis, reducing fracture risk, tooth sensitivity (in some toothpastes).Based on those ingredients, 101 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Strontium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Stronium Bone Power by Highland Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Strontium Bone Power is a single-ingredient supplement: strontium in a vegetable cellulose capsule. The other ingredients—magnesium trisilicate, magnesium stearate, and silica—are inactive binders and flow agents that help make the capsule.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: bone health and osteoporosis support.
  • We looked for evidence on: Osteoporosis, Fractures, Bone density, Fracture risk reduction.
  • The strongest evidence on file: Strontium is rated "Likely Effective" for Osteoporosis (Natural Medicines).
  • Also on file: Strontium is rated "Insufficient Reliable Evidence To Rate" for Fractures.

The evidence for strontium varies by use. It's rated effective for dental hypersensitivity and for pain from bony metastases (bone cancer spread).

For osteoporosis, it's likely effective—meaning solid research backs it. For osteoarthritis, the evidence is less clear (possibly effective), as is the research for prostate cancer.

The evidence, ingredient by ingredient Strontium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Strontium, particularly the ranelate form, carries some serious safety flags. Research shows it may increase the risk of blood clots (venous thromboembolism and pulmonary embolism) by about 50% and raise heart attack risk by about 1.6 times in people with osteoporosis.

The supplement is generally well tolerated at typical doses, though some people report diarrhea, nausea, headache, skin rash, and atopic dermatitis. Strontium should be avoided during pregnancy and breastfeeding—safety data advises against it.

Side effects, ingredient by ingredient Strontium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Strontium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 101 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Strontium Bone Power, check if you use estrogens, androgens like testosterone, antacids, quinolone antibiotics (such as ciprofloxacin), or tetracycline antibiotics (such as doxycycline). All of these have documented moderate interactions with strontium that may affect how well the supplement or your medication works—spacing doses 2 hours apart can help manage some of them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Strontium may help with bone density and certain types of bone pain, but it carries real cardiovascular risks that need careful thought, especially if you have heart disease or clotting concerns. If you take estrogens, androgens, antacids, or certain antibiotics, check with us first—spacing and timing matter.

Talk to your pharmacist about whether strontium is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 21, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Stronium Bone Power, straight from the product label.

Brand Highland Laboratories
Barcode (UPC) 768305738607
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 21, 2017
DSLD ID 79550
Product type Mineral
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Stronium Bone Power by Highland Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
30
UPC/BARCODE
768305738607
IngredientAmount% DV
Strontium350 mg--

Other ingredients: Vegetable Cellulose, Magnesium Trisilicate, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Quality Assured Earth Friendly

General Statements

% Daily Value

Formulation

No corn, soy, salt, yeast, gluten, milk & egg products, sugar, starch, or preservatives.

Suggested/Recommended/Usage/Directions

One capsule twice daily, as a dietary supplement.

Should be taken 2 hours before or after calcium products, as it will interfere with absorption of calcium.

Precautions

Warning: Not to be used by children or adolescents, as it can alter growing bones.

If pregnant, considering pregnancy, or lactating, consult a health care practitioner prior to use.

General

PR 738

See for yourself

Stronium Bone Power by Highland Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Stronium Bone Power by Highland Laboratories

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Strontium

Interacts with
101 drugs
350 mg per serving Form: Strontium Citrate

Strontium is a mineral that has been studied mainly for bone health and osteoporosis. The prescription form (strontium ranelate) showed benefit for fr...

Strontium monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Magnesium Trisilicate, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Stronium Bone Power by Highland Laboratories Drug Interactions

Want to check YOUR meds against Stronium Bone Power?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
101Drugs
101 Moderate

Ingredients driving the most interactions

Strontium 101

Each ingredient & the kinds of drugs it affects

For each ingredient in Stronium Bone Power with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Strontium5 drug types · 101 drugs

Androgens

Theoretically, androgens might reduce the excretion of strontium, potentially increasing its effects and adverse effects.
A small clinical study suggests that treatment with androgens such as testosterone, nandrolone, oxandrolone, and oxymetholone for 5-6 weeks might decrease urinary strontium excretion. The clinical significance of this interaction is unknown.

Likelihood Possible Evidence D
Antacids

Antacids can reduce the absorption of strontium, potentially decreasing its effectiveness.
Aluminum hydroxide and magnesium hydroxide can reduce absorption of strontium ranelate by 20% to 25%. Calcium can reduce its absorption to 60% to 70%. Avoid taking antacids within 2 hours of a dose of strontium ranelate. This interaction has also been reported with orally-administered radioactive strontium-85. It will likely also occur with other forms of strontium.

Likelihood Probable Evidence C
Estrogens

Theoretically, estrogens might reduce the excretion of strontium, potentially increasing its effects and adverse effects.
A small clinical study suggests that treatment with estrogens for 5-6 weeks might decrease urinary strontium excretion. The clinical significance of this interaction is unknown.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, strontium might decrease the absorption of quinolone antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with quinolones in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after quinolones to avoid an interaction.

Likelihood Probable Evidence D
Tetracycline Antibiotics

Theoretically, strontium might decrease the absorption of tetracycline antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with tetracyclines in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after tetracyclines to avoid an interaction.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Stronium Bone Power, from the product label.

Highland Laboratories

See all Highland Laboratories products
Name
Highland Laboratories
Pharmacist Counseling Corner

Stronium Bone Power by Highland Laboratories: Common Questions

Does Stronium Bone Power by Highland Laboratories interact with any medications?
Yes. Based on its ingredients, Stronium Bone Power has a known interaction with 101 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Stronium Bone Power contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. Strontium should be avoided during pregnancy and breastfeeding—safety data advises against it in both cases. Talk to your OB or midwife if you're considering bone support during this time.
What are the most common side effects?
Diarrhea, nausea, headache, and skin reactions like dermatitis or eczema are the ones people report most often. Serious side effects like blood clots or heart problems are rare but documented in the research.
Does strontium really help osteoporosis?
Yes—the evidence rates it as likely effective for osteoporosis, which means solid clinical research supports it. But keep in mind the cardiovascular risks; talk with your doctor about whether it's the right choice for you.
Can I take strontium with my antacid?
Not at the same time. Antacids can cut strontium absorption by 20% to 70%, which makes the supplement less effective. Wait at least 2 hours between taking them.
Is this safe to take long-term?
At typical doses (up to 2 grams daily), strontium is generally well tolerated long-term. However, research links it to increased risks of blood clots and heart attack, so long-term use should be discussed with your doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Stronium Bone Power label
Go deeper

The Full Monographs Behind Stronium Bone Power’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Stronium Bone Power's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Strontium 22 references
  1. Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
  2. Meunier PJ, Roux C, Seeman E, et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004;350:459-68.. PubMed
  3. El-Hajj Fuleihan G. Strontium ranelate--a novel therapy for osteoporosis or a permutation of the same? N Engl J Med 2004;350:504-6. PubMed
  4. Verberckmoes SC, De Broe ME, D'Haese PC. Dose-dependent effects of strontium on osteoblast function and mineralization. Kidney Int 2003;64:534-43. . PubMed
  5. Meunier PJ, Slosman DO, Delmas PD, et al. Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab 2002;87:2060-6.. DOI
  6. Brandi ML. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. Am J Med 1993;95:69S-74S. . PubMed
  7. Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. J Clin Endocrinol Metab 1966;26:566-72.
  8. Metastron prescribing information. Medi-Physics, Inc., Amersham Healthcare, Arlington Heights, IL, 1998. http://www.cancerpaintherapy.com/METATECHPAGE.htm. (Accessed 13 March 2004).
  9. Protelos European Summary of Product Characteristics. Les Laboratoires Servier, 2006. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. (Accessed 01 August 2006).
  10. US Department of Health and Human Services, Public Health Service. Agency for Toxic Substances and Disease Registry. Toxicological profile for strontium. April 2004. Available at: www.atsdr.cdc.gov/toxprofiles/tp159.pdf. (Accessed 8 August 2006).
  11. Apostolidis N, Paradellis T, Karydas A, et al. Calcium and strontium metabolic studies in patients on CAPD. Perit Dial Int 1998;18:410-4. DOI
  12. Ozgur S, Sumer H, Kocoglu G. Rickets and soil strontium. Arch Dis Child 1996;75:524-6. PubMed
  13. Schrooten I, Elseviers MM, Lamberts LV, et al. Increased serum strontium levels in dialysis patients: an epidemiological survey. Kidney Int 1999;56:1886-92. PubMed
  14. D'Haese PC, Couttenye MM, Lamberts LV, et al. Aluminum, iron, lead, cadmium, copper, zinc, chromium, magnesium, strontium, and calcium content in bone of end-stage renal failure patients. Clin Chem 1999;45:1548-56. DOI
  15. Pennington JA, Jones JW. Molybdenum, nickel, cobalt, vanadium, and strontium in total diets. J Am Diet Assoc 1987;87:1644-50. DOI
  16. O'Donnell S, Cranney A, Wells GA, et al. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane Musculoskeletal Group. Cochrane Database Syst Rev 2006;(4):CD005326. PubMed
  17. Protelos European Public Assessment Report, Scientific Discussion. European Medicines Agency, 2005. Available at: www.emea.eu.int/humandocs/Humans/EPAR/protelos/protelos.htm. (Accessed 10 October 2006).
  18. Rousselet F, El Solh N, Maurat JP, et al. Strontium and calcium metabolism. Interaction of strontium and vitamin D. C R Seances Soc Biol Fil 1975;169:322-9.
  19. O'Donnell, S., Cranney, A., Wells, G. A., Adachi, J. D., and Reginster, J. Y. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Cochrane.Database.Syst.Rev. 2006;3:CD005326. PubMed
  20. Rizzoli R, Chapurlat RD, Laroche JM, et al. Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis. Results of a 2-year study. Osteoporosis Int. 2012. 23(1):305-315. doi: 10.1007/s00198-011-1758-z. PubMed
  21. Reginster JY, Kaufman JM, Goemaere S, et al. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis. Osteoporos Int. 2012;23(3):1115-1122. doi: 10.1007/s00198-011-1847-z. PubMed
  22. Protos [Product Information]. Available at: http://www.guildlink.com.au/gc/ws/servier/pi.cfm?product=sepproto. Accessed May 1, 2018.

See these in context on the Strontium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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