Drug & supplement interaction

Strontium + Doripenem

Doripenem brand name: Doribax.

Moderate Interaction
Medically reviewed by · Updated October 2026
The bottom line Moderate

Doripenem falls into 2 drug categories that Strontium can interact with; the most serious is rated moderate. Theoretically, strontium might decrease the absorption of quinolone antibiotics.

Read the full interaction report
SeverityModerate
LikelihoodProbable
Interactions2
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Strontium and Doripenem

These two interact in 2 distinct ways. Each one is explained separately below.

Why Are There 2 Interactions?

Strontium interacts with whole categories of medication. Doripenem falls into 2 of those categories, so it can interact with Strontium in 2 different ways. We’ve listed each one below — your overall risk is driven by the most serious of them (Moderate).

Moderate

QUINOLONE ANTIBIOTICS

1 of 2

Why this applies to Doripenem

Doripenem falls under QUINOLONE ANTIBIOTICS — the group Strontium interacts with.

Theoretically, strontium might decrease the absorption of quinolone antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with quinolones in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after quinolones to avoid an interaction.
Severity Moderate Likelihood Probable Evidence D

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the thing to know first: this interaction was written for quinolone antibiotics (like ciprofloxacin or levofloxacin), and doripenem isn't a quinolone. It's a carbapenem, and it's given as an injection into a vein, not as a pill you swallow. The whole concern with strontium is that it binds up oral antibiotics in your stomach so they don't absorb well. Since doripenem goes straight into your bloodstream, that gut-binding problem really doesn't apply here.

So I wouldn't expect strontium to weaken your doripenem or change how it fights your infection. This is theoretical anyway, based on pharmacology rather than real cases. Still, strontium has its own heart-related cautions, so it's always worth a quick check with your pharmacist or doctor before combining anything.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Protelos European Summary of Product Characteristics. Les Laboratoires Servier, 2006. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. (Accessed 01 August 2006).
Moderate

TETRACYCLINE ANTIBIOTICS

2 of 2

Doripenem also falls under TETRACYCLINE ANTIBIOTICS.

Theoretically, strontium might decrease the absorption of tetracycline antibiotics.
Strontium is a divalent cation with similar properties to calcium. It is likely to form complexes with tetracyclines in the gastrointestinal (GI) tract, preventing absorption of the antibiotic. Recommend taking strontium supplements at least 2 hours before or after tetracyclines to avoid an interaction.
Severity Moderate Likelihood Probable Evidence D

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the honest picture: the interaction we have on file was written for oral tetracycline antibiotics, where strontium (a calcium-like mineral) can bind to the drug in your gut and block it from being absorbed. The worry there is a weaker antibiotic and a poorly treated infection.

Doripenem (Doribax) is different in one big way. It's given as an injection into a vein, not swallowed as a pill. Since it never travels through your stomach with the strontium, that gut-binding problem really doesn't apply here. So this particular concern is largely theoretical and, in practice, unlikely to matter for an IV antibiotic like doripenem. Still, if you're sick enough to need this medication, let your hospital team and pharmacist know about every supplement you take so they can keep an eye on things.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Protelos European Summary of Product Characteristics. Les Laboratoires Servier, 2006. Available at: www.servier.com/pro/osteoporose/protelos/protelos_spc.asp. (Accessed 01 August 2006).

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Strontium Also Interacts With Other Medications

Strontium has 100 moderate known drug interactions in our database — the Doripenem one above is among them. If you take anything else, check it against the full list below.

Moderate 100 No known interaction 2,730 (incl. Doripenem)
Taking anything else?

Check Another of Your Medications Against Strontium

Covers the 2,830 medications we’ve checked against Strontium. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Doripenem

This page covers Strontium only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Doripenem page lists 84 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Oleander (major), Para-aminobenzoic Acid (paba) (major), Acerola (moderate), Alpha-lipoic Acid (moderate) and Bacillus Coagulans (moderate).

By severity: 2 major · 75 moderate · 7 minor.

From our pharmacist’s overview on the Doripenem page

“Two entries here matter more than all the others, and I would read them first. Doripenem (Doribax) is an intravenous antibiotic reserved for serious bacterial infections, which means anything that weakens treatment or piles on risk deserves genuine caution.”

Reviewed by 2 · Jul 18, 2026

Open the Doripenem interaction page

One more smart check

Taking Strontium as Part of a Dietary Supplement Product? Check It for Interactions

We hold 347 real supplement products containing Strontium, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Strontium. Your product may carry other ingredients that interact with Doripenem too, on top of Strontium — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Strontium and Doripenem Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Strontium
Top half

#414 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Doripenem
Top half

#1,175 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Strontium

What is Strontium?

  • Bone health and osteoporosis
  • Reducing fracture risk
  • Tooth sensitivity (in some toothpastes)
  • Supporting bone density

Strontium is a mineral that has been studied mainly for bone health and osteoporosis. The prescription form (strontium ranelate) showed benefit for fracture risk but carries serious heart-related safety concerns, while the over-the-counter supplement form (strontium citrate) has much less evidence. Talk to your doctor or pharmacist before using it, especially if you have heart disease or are at risk for blood clots.

Read the full Strontium monograph & all interactions
Medication

About Doripenem Injection

What Is Doripenem Injection Used For?

Brand name: Doribax

  • Doripenem injection is used to treat serious infections of the urinary tract, kidney, and abdomen that are caused by bacteria. Doripenem injection is not approved by the Food and Drug Administration (FDA) to treat pneumonia that developed in people who were on a ventilator in a hospital. Doripenem injection is in a class of medications called carbapenem antibiotics. It works by killing bacteria.

  • Antibiotics such as doripenem injection will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

See full Doripenem Injection drug information
Keep checking

Other Drugs & Strontium

Browse every other medication we’ve checked against Strontium — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
100Moderate
0Minor
2,729No known interaction
100 Moderate 2,729 No interaction
Moderate

100 interactions

Showing 60 of 100 moderate interactions — see all 100 on the Strontium page.

No interaction 2,729 drugs checked — show the list

We also checked Strontium against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,729 medications checked with no known interaction — see the full Strontium list.

See the full Strontium interactions page
See every supplement checked against Doripenem, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Strontium monograph › Uses, safety, and every drug interaction in one place Doripenem supplement interactions › Every supplement checked against Doripenem, ranked by severity Doripenem Injection drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Strontium and Doripenem Together: Common Questions

Can you take Strontium with Doripenem?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
Why are there 2 interactions listed for Strontium and Doripenem?
Doripenem belongs to more than one drug category, and Strontium interacts with each of those categories a little differently. We list every one so nothing is missed — your overall risk is driven by the most serious of them.
How serious is the Strontium and Doripenem interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Doripenem and Strontium?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.