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Dietary supplement

Super Strength Water Pill with Potassium Ingredients & Drug Interactions

by Nature's Truth

Super Strength Water Pill with Potassium label
See full label image
Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Super Strength Water Pill with Potassium against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Super Strength Water Pill with Potassium is a dietary supplement by Nature's Truth with 5 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 1,295 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Uva-ursi, Buchu, Dandelion. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Super Strength Water Pill with Potassium by Nature's Truth

Ask about any prescription or over-the-counter medication and we check it for interactions with Super Strength Water Pill with Potassium by Nature's Truth — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Super Strength Water Pill with Potassium by Nature's Truth

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Artichoke” is listed as a grouped ingredient — the label gives one combined amount (25 mg) without saying how much of each component you get.
  • “Uva-ursi” is listed as a grouped ingredient — the label gives one combined amount (50 mg) without saying how much of each component you get.
  • “Dandelion” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

This product has five active ingredients. Potassium is the primary mineral — you're getting a supplement dose of this electrolyte, which your body needs for heart rhythm and muscle function.

Dandelion Root Extract, Uva-Ursi Leaf Extract, Artichoke Leaf Extract, and Buchu Leaf Extract are herbal components traditionally used to support fluid balance and kidney function. The tablet also contains inactive ingredients (cellulose, dicalcium phosphate, croscarmellose, magnesium stearate, stearic acid, and silica) that serve as binders and fillers.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: promote fluid balance and water retention.
  • We looked for evidence on: Urinary tract infections (UTIs), Edema, Bloating, Fluid retention.
  • The closest evidence on file: Uva Ursi is rated "Possibly Ineffective" for Urinary tract infections (UTIs) (Natural Medicines).
  • Also on file: Dandelion is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).

The evidence for how well this product works is mixed. Artichoke Leaf Extract is possibly effective for high cholesterol (hyperlipidemia) and indigestion (dyspepsia), based on small clinical trials.

For the other ingredients — potassium, dandelion, uva-ursi, and buchu — we don't hold effectiveness data, or the evidence for their intended uses (like joint pain, UTIs, or bronchitis) is insufficient to rate them reliably. Your pharmacist can discuss what the current research suggests for your specific reason for considering this product.

The evidence, ingredient by ingredient Potassium Artichoke Uva Ursi Dandelion Buchu

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is fine, but supplement doses can cause dangerously high blood levels in certain people, especially those with kidney disease — use only under medical guidance. The adverse effects you're most likely to notice with potassium are abdominal pain, belching, diarrhea, nausea, and vomiting.

Rarely, very high levels can cause heart rhythm problems, low blood pressure, and confusion. Dandelion is generally well tolerated but may cause diarrhea, heartburn, or stomach discomfort; in sensitive individuals, allergic reactions including anaphylaxis are rare.

Uva-Ursi is well tolerated in low doses short-term but can be toxic at high doses or with long-term use — at very high doses (20+ grams), it may cause serious effects like confusion, tremors, or difficulty breathing. Artichoke is generally well tolerated but may cause abdominal pain, diarrhea, flatulence, or nausea; allergic reactions are rare in people not sensitive to the daisy family.

Buchu lacks strong safety data at medicinal doses. For pregnancy: potassium from diet is fine, but supplements require medical guidance; dandelion and buchu lack enough reliable data — talk with your doctor; uva-ursi should be avoided in pregnancy; artichoke is best avoided in supplement form.

For breastfeeding: potassium and dandelion warrant a check with your doctor; uva-ursi and artichoke are best avoided; no data exists for buchu.

Side effects, ingredient by ingredient Potassium Artichoke Uva Ursi Dandelion Buchu

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Buchu, Uva Ursi, Dandelion, Artichoke, Potassium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 1,296 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist or doctor if you take potassium-sparing diuretics, ACE inhibitors, ARBs, antidiabetes drugs, anticoagulants or antiplatelet drugs (blood thinners), lithium, antihypertensive drugs (any blood pressure medication), or drugs metabolized by the liver (CYP1A2, CYP2C19, CYP2B6, or CYP3A4 substrates). Dandelion, uva-ursi, and artichoke all affect how your liver processes drugs, and potassium, dandelion, and buchu can all raise lithium levels dangerously.

These are the key medication types — list them for your pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is not simple — it mixes a mineral with real risks (potassium) and several herbal extracts that interact with many common medications. If you take blood pressure drugs, diabetes medications, blood thinners, or lithium, you absolutely need to talk with your pharmacist before starting.

Even if you don't take those, run your full medication list through the interaction checker below. Potassium supplements can be genuinely dangerous for people with kidney problems, so that's another conversation to have.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Super Strength Water Pill with Potassium, straight from the product label.

Brand Nature's Truth
Net contents 90 Vegetarian Tablet(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 306828
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Super Strength Water Pill with Potassium by Nature's Truth, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Tablet(s)
Maximum serving Sizes:
1 Vegetarian Tablet(s)
Servings per container
90
IngredientAmount% DV
Potassium20 mg1%
Artichoke25 mg--
Dandelion Root Extract2.5 mg--
Uva-ursi50 mg--
Uva-Ursi Leaf Extract10 mg--
Dandelion10 mg--
Artichoke Leaf Extract6.25 mg--
Buchu5 mg--
Buchu Leaf Extract1.25 mg--

Other ingredients: Cellulose, Dicalcium Phosphate, Croscarmellose, Magnesium Stearate, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Fluid balance

Caffeine free Gluten free Non GMO

Promotes fluid balance Regulate and maintain a healthy balance of fluid in your body with Nature's Truth Super Strength Water Pill.

Non-GMO No gluten, wheat, yeast, milk, lactose, soy, artificial color, artificial flavor, artificial sweetener, preservatives.

Vegetarian formula

100% Satisfaction Guarantee

FDA Statement of Identity

Dietary Supplement

Formula

These caffeine-free tablets are easy to swallow and feature the essential mineral Potassium, which works with sodium to promote water balance in the body. This vegetarian formula also includes additional herbal support from dandelion, artichoke, uva ursi, and buchu.

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) vegetarian tablet with water after each meal.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Avoid this product if you are allergic to ragweed or daisy-like flowers.

If any adverse reactions occur, immediately stop using this product and consult your doctor. If seal under cap is damaged or missing, do not use.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright 2021 Nature's Truth LLC

Seals/Symbols

Our non-GMO pledge Visit our website

General Statements

Vitamins

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Super Strength Water Pill with Potassium by Nature's Truth label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Super Strength Water Pill with Potassium label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Super Strength Water Pill with Potassium by Nature's Truth

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Potassium

Interacts with
62 drugs
20 mg per serving Form: Potassium Gluconate

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Artichoke

Interacts with
363 drugs
25 mg per serving

Artichoke leaf extract is a generally well-tolerated supplement that may have a mild cholesterol-lowering effect and is often used for indigestion, th...

Artichoke monograph & interactions

Uva-ursi

Interacts with
803 drugs
50 mg per serving

Uva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial...

Uva-ursi monograph & interactions

Dandelion

Interacts with
457 drugs
10 mg per serving Form: Taraxacum officinale

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for thes...

Dandelion monograph & interactions

Buchu

Interacts with
481 drugs
5 mg per serving Form: Agathosma betulina

Buchu is a fragrant South African shrub whose leaves are traditionally used for urinary and bladder complaints and as a diuretic. Solid human studies...

Buchu monograph & interactions

Other (inactive) ingredients: Cellulose, Dicalcium Phosphate, Croscarmellose, Magnesium Stearate, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Super Strength Water Pill with Potassium by Nature's Truth Drug Interactions

Want to check YOUR meds against Super Strength Water Pill with Potassium?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,295Drugs
1,257 Moderate 38 Minor

Ingredients driving the most interactions

Uva-ursi 803
Buchu 481
Dandelion 457
Artichoke 363
Potassium 62

Individual Drug Interactions

The ingredients in Super Strength Water Pill with Potassium interact with 1,295 drugs. Click any drug to see the details.

5 of the 5 ingredients in Super Strength Water Pill with Potassium interact with drugs. Each result below shows which ingredient is responsible. Uva-ursi Buchu Dandelion Artichoke Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Super Strength Water Pill with Potassium with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Uva-ursi6 drug types · 803 drugs

Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, uva ursi may decrease the metabolism of CYP2C19 substrates.
In vitro, uva ursi appears to inhibit cytochrome CYP2C19. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, uva ursi may decrease the metabolism of CYP3A4 substrates.
In vitro, uva ursi appears to inhibit CYP3A4. This effect has not been reported in humans.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, uva ursi may increase levels of drugs metabolized by glucuronidation.
In vitro, uva ursi extract appears to strongly inhibit UDP-glucuronosyltransferase (UGT) 1A1 (UGT1A1). However, uva ursi extract does not appear to inhibit UGT1A1 in animal models. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, uva ursi may increase lithium levels, necessitating a decrease in dose.
Uva ursi may have diuretic properties. Diuretics may increase lithium reabsorption with sodium in the proximal tubule of the kidney. Theoretically, uva ursi might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
Urinary Acidifying Agents

Effects of uva ursi in the urinary tract may be reduced by urinary acidifying agents.
Uva ursi seems to work best in alkaline urine. Theoretically, taking uva ursi with medications known to acidify the urine may decrease any effects of uva ursi on the urinary tract.

Likelihood Possible Evidence D
P-Glycoprotein Substrates

Theoretically, uva ursi may alter the levels of drugs transported by P-glycoprotein.
In vitro, uva ursi appears to inhibit the multi-drug transporter protein, P-glycoprotein. This effect has not been reported in humans.

Likelihood Possible Evidence D
Uva-ursi full monograph & interactions

Buchu3 drug types · 481 drugs

Anticoagulant/Antiplatelet Drugs

Buchu may have antiplatelet effects. Theoretically, buchu may enhance the effects of anticoagulant or antiplatelet drugs and increase the risk of bleeding in some patients. Some anticoagulant or antiplatelet drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Buchu contains pulegone, a known hepatotoxin. There is some concern that buchu may adversely affect the liver, especially when the leaf is used in large doses or the oil is ingested. Theoretically, concomitant use with hepatotoxic drugs might increase the risk of liver damage. Some of these drugs include acarbose (Precose, Prandase), amiodarone (Cordarone), atorvastatin (Lipitor), azathioprine (Imuran), carbamazepine (Tegretol), cerivastatin (Baycol), diclofenac (Voltaren), felbamate (Felbatol), fenofibrate (Tricor), fluvastatin (Lescol), gemfibrozil (Lopid), isoniazid, itraconazole, (Sporanox), ketoconazole (Nizoral), leflunomide (Arava), lovastatin (Mevacor), methotrexate (Rheumatrex), nevirapine (Viramune), niacin, nitrofurantoin (Macrodantin), pioglitazone (Actos), pravastatin (Pravachol), pyrazinamide, rifampin (Rifadin), ritonavir (Norvir), rosiglitazone (Avandia), simvastatin (Zocor), tacrine (Cognex), tamoxifen, terbinafine (Lamisil), valproic acid, and zileuton (Zyflo)

Likelihood Possible Evidence D
Lithium

Buchu is thought to have diuretic properties. Theoretically, buchu might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Buchu full monograph & interactions

Dandelion7 drug types · 457 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking dandelion root along with anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro research suggests that dandelion root inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, dandelion might increase the risk for hypoglycemia when used with antidiabetes drugs.
Laboratory research suggests that dandelion extract may have moderate alpha-glucosidase inhibitor activity and might also increase insulin secretion. Also, in a case report, a 58-year-old woman with type 2 diabetes who was being treated with insulin developed hypoglycemia 2 weeks after beginning to eat salads containing dandelion.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, dandelion might increase levels of drugs metabolized by CYP1A2.
Laboratory research suggests that dandelion might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, until more is known, watch for an increase in the levels of drugs metabolized by CYP1A2 in patients taking dandelion.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, dandelion might increase the clearance of drugs that are UDP-glucuronosyltransferase substrates.
There is some preliminary evidence that dandelion might induce UDP-glucuronosyltransferase, a phase II enzyme.

Likelihood Possible Evidence D
Lithium

Theoretically, through diuretic effects, dandelion might reduce excretion and increase levels of lithium.
Animal research suggests that dandelion has diuretic properties. As diuretics can increase serum lithium levels, the dose of lithium might need to be decreased when taken with dandelion.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically, dandelion might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Dandelion contains significant amounts of potassium.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, dandelion might lower fluoroquinolone levels.
Animal research shows that dandelion reduces absorption of ciprofloxacin and can lower levels by 73%. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Dandelion full monograph & interactions

Artichoke4 drug types · 363 drugs

Antidiabetes Drugs

Theoretically, artichoke leaf extract may increase the risk of hypoglycemia when taken with antidiabetes drugs.
A meta-analysis of small clinical studies shows that taking artichoke leaf extract for 8-12 weeks can modestly reduce fasting plasma glucose when compared with placebo.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, artichoke leaf extract may increase the risk of hypotension when taken with antihypertensive drugs.
A meta-analysis of small clinical studies in patients with hypertension shows that taking artichoke can reduce systolic blood pressure by around 3 mmHg and diastolic blood pressure by around 2 mmHg when compared with placebo.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, artichoke might increase serum levels of drugs metabolized by CYP2B6.
In vitro research shows that artichoke leaf extract inhibits CYP2B6 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, artichoke might increase serum levels of drugs metabolized by CYP2C19.
In vitro research shows that artichoke leaf extract inhibits CYP2C19 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Artichoke full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Super Strength Water Pill with Potassium, from the product label.

Nature's Truth

See all Nature's Truth products
Name
Nature's Truth LLC
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
1-844-544-1030
Web Address
naturestruthproducts.com
Pharmacist Counseling Corner

Super Strength Water Pill with Potassium by Nature's Truth: Common Questions

Does Super Strength Water Pill with Potassium by Nature's Truth interact with any medications?
Yes. Based on its ingredients, Super Strength Water Pill with Potassium has a known interaction with 1,295 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Super Strength Water Pill with Potassium contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I have kidney disease?
No — potassium supplements can cause dangerously high blood levels, especially in people with kidney disease. Talk with your doctor or pharmacist first; they may advise against it entirely or need to monitor you closely.
What's the most likely side effect I'll notice?
Stomach upset is the most common — abdominal pain, diarrhea, nausea, belching, or flatulence. Start with the lowest dose and take it with food if you experience these.
Is artichoke in this product effective for anything?
Artichoke extract is possibly effective for high cholesterol and indigestion. The other ingredients don't have reliable evidence we can point to, so effectiveness is less clear.
Is it safe to use while pregnant?
Potassium from food is fine, but supplements need medical guidance during pregnancy. Uva-ursi should be avoided; dandelion, artichoke, and buchu lack enough reliable data — talk with your doctor or midwife before using this product.
Can I take this with my blood pressure medication?
That depends on which blood pressure drug you take. ACE inhibitors and ARBs both have a Moderate risk of raising your potassium too high, and artichoke may lower your pressure further. Check with your pharmacist before starting.
What does 'water pill' mean in the product name?
It refers to the diuretic effect — the herbs are traditionally thought to increase urine flow and help your body shed excess fluid. The potassium is added because regular diuretics can deplete it, but with potassium-sparing diuretics or certain blood pressure drugs, that becomes a problem.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Super Strength Water Pill with Potassium is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Super Strength Water Pill with Potassium label
Go deeper

The Full Monographs Behind Super Strength Water Pill with Potassium’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Artichoke

Interacts with 363 drugs

Artichoke leaf extract is a generally well-tolerated supplement that may have a mild cholesterol-lowering effect and is often used for indigestion, though the evidence is modest. It is not a...

Read the full Artichoke monograph → Herb & supplement monograph

Uva Ursi

Interacts with 803 drugs

Uva ursi is a traditional herb used mainly for urinary tract infections, and its leaves contain a compound called arbutin that may have antimicrobial effects in the urine. Evidence in people...

Read the full Uva Ursi monograph → Herb & supplement monograph

Dandelion

Interacts with 457 drugs

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for these uses is very limited, so its benefits...

Read the full Dandelion monograph → Herb & supplement monograph

Buchu

Interacts with 481 drugs

Buchu is a fragrant South African shrub whose leaves are traditionally used for urinary and bladder complaints and as a diuretic. Solid human studies are lacking, so its benefits are largely...

Read the full Buchu monograph →
Sources

Sources & How We Checked

Super Strength Water Pill with Potassium's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 66 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
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Artichoke 16 references
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Dandelion 27 references
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Uva Ursi 8 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  3. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
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  6. de Arriba SG, Naser B, Nolte KU. Risk assessment of free hydroquinone derived from Arctostaphylos Uva-ursi folium herbal preparations. Int J Toxicol. 2013;32(6):442-453.
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See these in context on the Uva Ursi monograph →

Buchu 3 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
  3. Moolla A, Viljoen AM. 'Buchu' - Agathosma betulina and Agathosma crenulata (Retaceae): a review. J Ethnopharmacol 2008;119(3):413-9.

See these in context on the Buchu monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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