Interactions on record — worth a quick check against your medications. Based on 4 of 8 ingredients. Check your meds →
Dietary supplement

The Original NitroFusion Multi Source Protein Vanilla Ingredients & Drug Interactions

by NitroFusion

The Original NitroFusion Multi Source Protein Vanilla label
See full label image
Powder Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking The Original NitroFusion Multi Source Protein Vanilla against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

The Original NitroFusion Multi Source Protein Vanilla is a dietary supplement by NitroFusion with 8 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,038 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Sodium, Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against The Original NitroFusion Multi Source Protein Vanilla by NitroFusion

Ask about any prescription or over-the-counter medication and we check it for interactions with The Original NitroFusion Multi Source Protein Vanilla by NitroFusion — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of The Original NitroFusion Multi Source Protein Vanilla by NitroFusion

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 6 of its 6 active ingredients.
  • “NitroFusion Infused Proprietary Amino Acid Blend” is a proprietary blend — the label gives one combined amount (25,000 mg) without saying how much of each component you get.

This powder contains 5 active ingredients: L-glutamine, sodium, potassium, a proprietary amino acid blend, and a proprietary enzyme blend. L-glutamine is an amino acid used to support muscle recovery and immune function, especially after surgery or in critical illness.

The amino acid blend (including 5,375 mg of branched-chain amino acids, or BCAAs) supplies the building blocks your muscles use to repair and grow. Sodium and potassium are electrolytes that help maintain fluid balance and nerve signaling.

The enzyme blend aids protein digestion. Beyond those actives, the product contains inactive ingredients like the multi-source protein base, fructose, natural flavors, guar gum, silica, stevia, and glycine.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Complete plant protein with amino acids.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, HIV/AIDS-related wasting, Malnutrition, Muscular dystrophy, Postoperative recovery — and 4 related terms.
  • The strongest evidence on file: Glutamine is rated "Possibly Effective" for HIV/AIDS-related wasting (Natural Medicines).
  • Also on file: Glutamine is rated "Possibly Effective" for Postoperative recovery.
  • Also on file: Glutamine is rated "Possibly Ineffective" for Athletic performance, Muscular dystrophy.

L-glutamine in this product is rated Effective for sickle cell disease, and Possibly Effective for HIV/AIDS-related wasting, recovery after surgery, and critical illness from trauma. We don't have effectiveness data on file for sodium or potassium in this formulation, and the proprietary blends and BCAA content are not rated in our data.

How well this product works for you will depend on your individual needs and the amounts of each ingredient per serving.

The evidence, ingredient by ingredient Black Psyllium Sodium Potassium Glutamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

L-glutamine is generally well tolerated in healthy adults. The most common side effects from oral glutamine are belching, bloating, gas, nausea, vomiting, diarrhea, and abdominal pain — especially at high doses (10–30 grams daily).

A small number of people with bipolar disorder taking glutamine have reported mood changes (mania). People with kidney or liver disease should only use L-glutamine under medical supervision, and it's not recommended in supplement doses during pregnancy or breastfeeding unless a doctor advises it.

Sodium is well tolerated at normal dietary levels but too much is linked to high blood pressure and heart strain; avoid sodium supplements unless your doctor says otherwise. Potassium from food is fine, but supplements can cause dangerously high blood levels in some people, especially those with kidney disease — use it only with medical guidance during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Black Psyllium Sodium Potassium Glutamine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Black Psyllium, Potassium, Glutamine, Sodium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications; heart-rhythm medications; lithium.
  • For scale: 2,039 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on anticonvulsant (seizure) medications, blood pressure drugs (especially ACE inhibitors, ARBs, or antihypertensive drugs), potassium-sparing water pills (diuretics), lithium, corticosteroids, didanosine, or any medication containing sodium. The sodium and potassium in this powder can significantly alter how these drugs work or raise mineral levels to unsafe heights.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This protein powder is a reasonable choice if you're recovering from surgery, managing critical illness, or dealing with HIV/AIDS-related wasting — though the strength of the evidence varies by condition. The sodium and potassium content makes it especially important to check with your own doctor or pharmacist before taking it, particularly if you're on blood pressure drugs, diuretics, lithium, or seizure medications.

Talk over your specific situation with them before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about The Original NitroFusion Multi Source Protein Vanilla, straight from the product label.

Brand NitroFusion
Barcode (UPC) 890985001723
Net contents 2 lb; 908 g
Market status On market
Date entered into DSLD Mar 25, 2013
DSLD ID 18953
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for The Original NitroFusion Multi Source Protein Vanilla by NitroFusion, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
35 Gram(s)
Maximum serving Sizes:
35 Gram(s)
Servings per container
26
UPC/BARCODE
890985001723
IngredientAmount% DV
Calories136 {Calories}--
Total Carbohydrates5 g2%
L-Glutamine4000 mg--
Calories from Fat20 {Calories}--
Dietary Fiber1 g4%
Protein25 g50%
Saturated Fat0 g--
Sodium420 mg18%
Potassium40 mg1%
Cholesterol0 g--
Total Fat2 g3%
Sugar4 g--
NitroFusion Infused Proprietary Amino Acid Blend25000 mg--
Providing 5,375 mg BCAAs5375 mg--
NitroFusion Proprietary Enzyme Blend100 mg--

Other ingredients: NitroFusion Proprietary Blend Multi Source Protein, Fructose, Natural Flavors, Guar Gum, Silica, Stevia, Glycine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

ANS ARIZONA NUTRITIONAL SCIENCES www.azns.us

General Statements

NITROGEN INFUSED Technology - COMPLETE PLANT SOURCED PROTEIN - CONTAINS ALL ESSENTIAL & NON-ESSENTIAL AMINO ACIDS - MORE BCAAs AND L-GLUTAMINE THAN WHEY

- MIXES EASILY, UNCOMMONLY GREAT TASTE

{graph} BIOLOGICAL VALUE OF SELECT PROTEINS

"As with all agricultural products; taste, color, and potency vary with batch, season, and natural weather fluctuation. We have chosen to use an industry accepted average and actual numbers may vary. This number is for comparison purposes only."

100% NATURAL MULTI SOURCE PROTEIN

- ADVANCED COMPLETE PROTEIN - INFUSED BCAAs & L-GLUTAMINE

AMINO ACID PROFILE (Grams Per 25g of Protein) Alanine 975 mg Arginine 2,000 mg Aspartic Acid 2,500 mg Cysteine 275 mg Glutamine 4,000 mg Glycine 1,200 mg Histidine 1,275 mg Isoleucine 1,450 mg Leucine 2,325 mg Lysine 1,500 mg Methionine 325 mg Phenylalanine 1,250 mg Proline 1,125 mg Serine 1,175 mg Threonine 875 mg Tryptophan 225 mg Tyrosine 900 mg Valine 1,600 mg

cGMP Manufacturing MADE IN THE USA

"Please Note: we have chosen to use all natural fruit sugar (fructose) to sweeten our product. Fructose is metabolized very slowly through your liver and will NOT cause a spike in blood sugar level or insulin. Fructose is considered a low glycemic and has a score of between 18 and 22.

Formula

- 25g OF CONCENTRATED PROTEIN IN ONE HEAPING 35g SCOOP

- LACTOSE FREE, EASILY DIGESTED, NO STOMACH IRRITATION - HYPOALLERGENIC, VEGAN APPROVED, NON-GMO - CHOLESTEROL FREE, LOW GLYCEMIC LOAD

- HYPOALLERGENIC & GLUTEN FREE - NO DAIRY - NO SOY - NO ANIMAL

PROTEIN 25g

Formulation

- 100% NATURAL, NO ARTIFICIAL COLORS OR SWEETENERS

FDA Statement of Identity

DIETARY SUPPLEMENT

Suggested/Recommended/Usage/Directions

DIRECTIONS: Add one heaping scoop to 8 - 10 oz of chilled water or preferred beverage (vary the amount of liquid to achieve a desired consistency) in a shaker cup or blender and mix for about 5 seconds. Drink and enjoy 1-3 shakes per day as an addition to regular meals.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

The Original NitroFusion Multi Source Protein Vanilla by NitroFusion label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

The Original NitroFusion Multi Source Protein Vanilla label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in The Original NitroFusion Multi Source Protein Vanilla by NitroFusion

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size35 Gram(s) Dosage formPowder Servings per container26 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
1 g per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Protein

25 g per serving

Sodium

Interacts with
205 drugs
420 mg per serving

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets g...

Sodium monograph & interactions

Potassium

Interacts with
62 drugs
40 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Sugar

4 g per serving Form: Fructose

NitroFusion Infused Proprietary Amino Acid Blend

25000 mg per serving

NitroFusion Proprietary Enzyme Blend

100 mg per serving Form: Bromelain and Alpha Galactosidase

Other (inactive) ingredients: NitroFusion Proprietary Blend Multi Source Protein, Fructose, Natural Flavors, Guar Gum, Silica, Stevia, Glycine. These complete the product’s ingredient list but are not active constituents.

Interaction report

The Original NitroFusion Multi Source Protein Vanilla by NitroFusion Drug Interactions

Want to check YOUR meds against The Original NitroFusion Multi Source Protein Vanilla?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,038Drugs
290 Moderate 1,748 Minor

Ingredients driving the most interactions

Dietary Fiber 2,025
Sodium 205
Potassium 62
L-Glutamine 50

Individual Drug Interactions

The ingredients in The Original NitroFusion Multi Source Protein Vanilla interact with 2,038 drugs. Click any drug to see the details.

4 of the 8 ingredients in The Original NitroFusion Multi Source Protein Vanilla interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Sodium Potassium L-Glutamine

Each ingredient & the kinds of drugs it affects

For each ingredient in The Original NitroFusion Multi Source Protein Vanilla with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B
Dietary Fiber full monograph & interactions

Sodium7 drug types · 205 drugs

Antihypertensive Drugs

Theoretically, a high intake of dietary sodium might reduce the effectiveness of antihypertensive drugs.
High intake of dietary sodium can increase systolic and diastolic blood pressure. Also, high intake of sodium may necessitate increased use of antihypertensive medications to achieve blood pressure control in some patients, such as those with chronic kidney disease.

Likelihood Probable Evidence A
Corticosteroids

Concomitant use of mineralocorticoids and some glucocorticoids with sodium supplements might increase the risk of hypernatremia.
Mineralocorticoids and some glucocorticoids (corticosteroids) cause sodium retention. This effect is dose-related and depends on mineralocorticoid potency. It is most common with hydrocortisone, cortisone, and fludrocortisone, followed by prednisone and prednisolone.

Likelihood Possible Evidence D
Didanosine (Videx)

Concomitant use of didanosine with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia.
Didanosine formulations contain a significant amount of sodium.

Likelihood Probable Evidence C
Lithium

Altering dietary intake of sodium might alter the levels and clinical effects of lithium.
High sodium intake can reduce plasma concentrations of lithium by increasing lithium excretion. Reducing sodium intake can significantly increase plasma concentrations of lithium and cause lithium toxicity in patients being treated with lithium carbonate. Stabilizing sodium intake is shown to reduce the percentage of patients with lithium level fluctuations above 0.8 mEq/L. Patients taking lithium should avoid significant alterations in their dietary intake of sodium.

Likelihood Probable Evidence B
Sodium Phosphates

Theoretically, concomitant use of sodium phosphate with sodium supplements might increase the risk of hypernatremia.
Use of high doses (> 45 mL in 24 hours) of sodium phosphate, such as those used for bowel cleansing before surgery, can lead to serious electrolyte disturbances, including hypernatremia. The risk of hypernatremia is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Sodium-Containing Drugs

Concomitant use of sodium-containing drugs with additional sodium from dietary or supplemental sources may increase the risk of hypernatremia and long-term sodium-related complications.
The Chronic Disease Risk Reduction (CDRR) intake level of 2.3 grams of sodium daily indicates the intake at which it is believed that chronic disease risk increases for the apparently healthy population. Some medications contain high quantities of sodium. When used in conjunction with sodium supplements or high-sodium diets, the CDRR may be exceeded. Additionally, concomitant use may increase the risk for hypernatremia; this risk is highest in the elderly and people with other risk factors for electrolyte disturbances.

Likelihood Possible Evidence D
Tolvaptan (Samsca)

Theoretically, concomitant use of tolvaptan with sodium might increase the risk of hypernatremia.
Tolvaptan is a vasopressin receptor 2 antagonist that is used to increase sodium levels in patients with hyponatremia. Patients taking tolvaptan should use caution with the use of sodium salts such as sodium chloride.

Likelihood Probable Evidence C
Sodium full monograph & interactions

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions

L-Glutamine1 drug type · 50 drugs

Anticonvulsants

Theoretically, glutamine might antagonize the effects of anticonvulsant medications.
Glutamine is metabolized to the excitatory neurotransmitter glutamate. Glutamate might have antagonistic effects with anticonvulsant drugs. However, this interaction has not yet been reported in humans.

Likelihood Possible Evidence D
L-Glutamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for The Original NitroFusion Multi Source Protein Vanilla, from the product label.

NitroFusion

See all NitroFusion products
Web Address
www.NitroFusion.us
Pharmacist Counseling Corner

The Original NitroFusion Multi Source Protein Vanilla by NitroFusion: Common Questions

Does The Original NitroFusion Multi Source Protein Vanilla by NitroFusion interact with any medications?
Yes. Based on its ingredients, The Original NitroFusion Multi Source Protein Vanilla has a known interaction with 2,038 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
The Original NitroFusion Multi Source Protein Vanilla contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or breastfeeding?
The L-glutamine content is rated Likely Safe in pregnancy and lactation. Sodium is Likely Safe in pregnancy but Possibly Unsafe in breastfeeding — and potassium is Likely Safe in both. Because we don't have full safety data on the blends and BCAAs, talk with your doctor or pharmacist before using this product while pregnant or nursing to make sure it's right for you.
What's L-glutamine supposed to do?
L-glutamine is an amino acid your body uses to repair muscle, support immune function, and recover after surgery or serious illness. It's rated Effective for sickle cell disease and Possibly Effective for HIV/AIDS-related wasting, post-surgery recovery, and critical illness from trauma.
What are the common side effects?
The most common side effects from L-glutamine are belching, bloating, gas, nausea, vomiting, diarrhea, and stomach pain. Sodium and potassium at normal dietary levels don't typically cause problems, but too much of either can cause serious effects — high sodium raises blood pressure and strains your heart, and high potassium can cause irregular heartbeat and dangerous drops in blood pressure.
Can I take this if I have kidney disease?
Check with your doctor first. L-glutamine requires medical supervision in kidney or liver disease, and potassium supplements are risky in kidney disease because your kidneys may not clear excess potassium safely. Your doctor or pharmacist can tell you whether this product is right for you.
Does this contain any fillers?
Yes, it contains several inactive ingredients: fructose, natural flavors, guar gum, silica, stevia, and glycine. These are binders and sweeteners that help with texture and taste — they're not active ingredients but are part of the formula.
What if I'm on blood pressure medication?
The sodium content in this product can reduce how well blood pressure drugs work, and the potassium can raise your blood levels dangerously high if you're on certain blood pressure medications like ACE inhibitors or ARBs. Talk with your doctor or pharmacist before taking it to make sure it's safe alongside your specific medications.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

The Original NitroFusion Multi Source Protein Vanilla label
Go deeper

The Full Monographs Behind The Original NitroFusion Multi Source Protein Vanilla’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Psyllium

Interacts with 2,025 drugs

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...

Read the full Black Psyllium monograph → Herb & supplement monograph

Sodium

Interacts with 205 drugs

Sodium is an essential mineral and electrolyte your body needs to balance fluids, support nerves, and help muscles work. Most people in modern diets get more than enough—often too much—from...

Read the full Sodium monograph → Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph →
Sources

Sources & How We Checked

The Original NitroFusion Multi Source Protein Vanilla's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 79 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
  2. Bozzetti F, Biganzoli L, Gavazzi C, et al. Glutamine supplementation in cancer patients receiving chemotherapy: a double-blind randomized study. Nutrition 1997;13:748-51.. PubMed
  3. Mebane AH. L-Glutamine and mania. Am J Psychiatry 984;141:1302-3.
  4. Meldrum BS. Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 2000;130:1007S-15S.. PubMed
  5. Garlick PJ. Assessment of the safety of glutamine and other amino acids. J Nutr 2001;131:2556S-61S.. PubMed
  6. Chapman AG. Glutamate and epilepsy. J Nutr 2000;130:1043S-5S.. PubMed
  7. Ziegler TR. Glutamine supplementation in cancer patients receiving bone marrow transplantation and high dose chemotherapy. J Nutr 2001;131:2578S-84S.. PubMed
  8. Laviano A, Molfino A, Lacaria MT, Canelli A, De Leo S, Preziosa I, Rossi Fanelli F. Glutamine supplementation favors weight loss in nondieting obese female patients. A pilot study. Eur J Clin Nutr. 2014 Nov;68(11):1264-6. PubMed
  9. Endari (l-glutamine) [package insert]. Torrance, CA: Emmaus Medical,Inc; 2017.
  10. Niihara Y, Miller ST, Kanter J, et al. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. N Engl J Med 2018;379(3):226-35. doi: 10.1056/NEJMoa1715971.
  11. Ogden HB, Child RB, Fallowfield JL, et al. Gastrointestinal Tolerance of Low, Medium and High Dose Acute Oral l-Glutamine Supplementation in Healthy Adults: A Pilot Study. Nutrients. 2020;12(10):2953. PubMed

See these in context on the Glutamine monograph →

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
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See these in context on the Black Psyllium monograph →

Sodium 38 references
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See these in context on the Sodium monograph →

Potassium 12 references
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See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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