Thymucin Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Thymucin against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Thymucin is a dietary supplement by Integrative Therapeutics with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,125 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Astragalus (Astragalus membranaceus) root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Thymucin by Integrative Therapeutics
Ask about any prescription or over-the-counter medication and we check it for interactions with Thymucin by Integrative Therapeutics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Thymucin by Integrative Therapeutics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Thymucin contains two active ingredients: astragalus root extract and thymus powder. Astragalus is a traditional herb that has been used in Asian medicine, while thymus powder comes from thymus tissue.
The capsule itself includes several inactive ingredients — cellulose, gelatin, magnesium stearate, titanium dioxide, and silicon dioxide — which help hold and deliver the active ingredients.
Does it work?
Not established
The evidence we hold for astragalus covers uses like allergic rhinitis (hay fever), amenorrhea, aplastic anemia, angina, asthma, and beta-thalassemia, but the reliability is insufficient in each case to make a confident recommendation. We have no effectiveness data on file for thymus powder.
If you're considering Thymucin for a specific health concern, talk with your doctor or pharmacist about what the broader research literature shows.
How safe is it?
Well-documented data
Astragalus is generally well tolerated in healthy adults over the short term, but quality human safety data is limited. The safety data advises against use during pregnancy and breastfeeding.
In clinical trials, astragalus has been associated with dizziness and, rarely, palpitations or rash, though these effects may not have been caused by astragalus itself. We have no safety information on file for thymus powder.
Meds to double-check
Moderate interaction found
Before you take Thymucin, check whether you're on any immunosuppressants (used for organ transplant or autoimmune conditions), lithium, cyclophosphamide, or diabetes medications. These are the drug types where astragalus has documented moderate-severity interactions.
If you take any of these, confirm with your doctor or pharmacist that this product is safe for you.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Thymucin may be worth considering if you're interested in traditional immune-support herbs, but the evidence for its effectiveness is not well established in our data. If you take immunosuppressants, lithium, diabetes medications, or chemotherapy, you'll want to check this product with your doctor or pharmacist first — the interactions are real.
Talk it over with your own healthcare provider before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Thymucin, straight from the product label.
| Brand | Integrative Therapeutics |
|---|---|
| Barcode (UPC) | 871791002531 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Apr 25, 2019 |
| DSLD ID | 201152 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Thymucin by Integrative Therapeutics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| Dietary Fiber | 1 Gram(s) | 2% |
| Astragalus (Astragalus membranaceus) root extract | 250 mg | -- |
| Thymus powder | 750 mg | -- |
Other ingredients: Cellulose, Gelatin, Magnesium Stearate, Titanium Dioxide color, Silicon Dioxide
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
Keep out of reach of children.
Safety sealed with printed inner seal. Do not use if seal is broken or missing.
If pregnant, nursing, or taking prescription drugs, consult your healthcare professional prior to use.
Formulation
Contains no sugar, salt, yeast, wheat, gluten, soy, dairy products, artificial flavoring, or preservatives.
Brand IP Statement(s)
2018 Integrative Therapeutics, LLC
General
LZ74006.D01 BLK400D
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Immune support
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Recommendation: Take 2 capsules daily, or as recommended by your healthcare professional.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Thymucin by Integrative Therapeutics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Thymucin by Integrative Therapeutics
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactionsAstragalus (Astragalus membranaceus) root extract
Interacts with208 drugs
Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...
Astragalus (Astragalus membranaceus) root extract monograph & interactionsThymus powder
Other (inactive) ingredients: Cellulose, Gelatin, Magnesium Stearate, Titanium Dioxide color, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.
Thymucin by Integrative Therapeutics Drug Interactions
HelloPharmacist Interaction Report
Thymucin by Integrative Therapeutics contains astragalus, which has documented interactions with several medication types.
The most serious concern is a moderate-severity interaction with immunosuppressants — astragalus may stimulate immune function in ways that could reduce the effectiveness of drugs used to prevent organ rejection or manage autoimmune conditions.
Read the full breakdown — every affected drug type, severity by severity
Astragalus also interacts moderately with lithium (a mood stabilizer), potentially raising its levels and side effects through diuretic properties that reduce how your body clears it. It may interfere with cyclophosphamide, a chemotherapy drug used for cancer and certain autoimmune diseases, though the evidence from animal studies is mixed.
Additionally, astragalus could theoretically increase the risk of low blood sugar (hypoglycemia) when taken with diabetes medications.
We could not check thymus powder — we hold no interaction data for it. Altogether, these interactions span 208 individual medications.
Before you start Thymucin, run your exact medications through the checker on this page, and talk with your doctor or pharmacist about whether it's right for you.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Thymucin?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Thymucin interact with 2,125 drugs. Click any drug to see the details.
2 of the 3 ingredients in Thymucin interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Astragalus (Astragalus membranaceus) root extract
Ozanimod HydrochlorideZeposia
How Ozanimod Hydrochloride interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Ozanimod Hydrochloride interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ozanimod Hydrochloride interactionPalbociclibIbrance
How Palbociclib interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Palbociclib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Palbociclib interactionPalivizumabSynagis
How Palivizumab interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Palivizumab interactionPazopanibVotrient
How Pazopanib interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Pazopanib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Pazopanib interactionPioglitazoneActos
How Pioglitazone interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Pioglitazone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Pioglitazone interactionPomalidomidePomalyst
How Pomalidomide interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Pomalidomide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Pomalidomide interactionPramlintideSymlin
How Pramlintide interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Pramlintide interactionPrednisoloneCortalone, Delta Cortef, Pred Forte, Prednisolone, Solupred, Sterane
How Prednisolone interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Prednisolone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Prednisolone interactionPrednisoneCortan, Deltasone, Meticorten, Orasone, Prednicen-M, Prednisone +2 more
How Prednisone interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Prednisone interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Prednisone interactionPretomanidPretomanid
How Pretomanid interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Pretomanid interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Pretomanid interactionRepaglinideGlucoNorm, Prandin
How Repaglinide interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Repaglinide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Repaglinide interactionRisankizumab-rzaaSkyrizi
How Risankizumab-rzaa interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Risankizumab-rzaa interactionRitlecitinibLitfulo
How Ritlecitinib interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Ritlecitinib interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ritlecitinib interactionRituximabRituxan
How Rituximab interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Rituximab interactionRituximab-abbsTruxima
How Rituximab-abbs interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Rituximab-abbs interactionRituximab-arrxRiabni
How Rituximab-arrx interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Rituximab-arrx interactionRituximab-pvvrRuxience
How Rituximab-pvvr interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Rituximab-pvvr interactionRosiglitazone MaleateAvandia
How Rosiglitazone Maleate interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Rosiglitazone Maleate interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Rosiglitazone Maleate interactionSarilumabKevzara
How Sarilumab interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Sarilumab interactionSatralizumabEnspryng
How Satralizumab interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Satralizumab interactionSaxagliptinOnglyza
How Saxagliptin interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Saxagliptin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Saxagliptin interactionSaxagliptin, Metformin XrKombiglyze
How Saxagliptin, Metformin Xr interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Saxagliptin, Metformin Xr interactionAstragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Saxagliptin, Metformin Xr interactionSemaglutideOzempic, Rybelsus, Wegovy
How Semaglutide interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Semaglutide interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Semaglutide interactionSimvastatin, SitagliptinJuvisync
How Simvastatin, Sitagliptin interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Simvastatin, Sitagliptin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Simvastatin, Sitagliptin interactionSiponimodMayzent
How Siponimod interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Siponimod interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Siponimod interactionSirolimusRapamune
How Sirolimus interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Sirolimus interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Sirolimus interactionSirolimus (albumin Bound)Fyarro
How Sirolimus (albumin Bound) interacts with Thymucin — through 1 ingredient. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractImmunosuppressants Moderate
Interaction Summary
Theoretically, astragalus might interfere with immunosuppressive therapy.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Sirolimus (albumin Bound) interactionSitagliptinJanuvia, Zituvio
How Sitagliptin interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Sitagliptin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Sitagliptin interactionSitagliptin, MetforminZituvimet
How Sitagliptin, Metformin interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Sitagliptin, Metformin interactionAstragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Sitagliptin, Metformin interactionSotagliflozinInpefa
How Sotagliflozin interacts with Thymucin — through 2 ingredients. Tap an ingredient for the detail:
Astragalus (astragalus Membranaceus) Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Astragalus (astragalus Membranaceus) Root Extract + Sotagliflozin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Sotagliflozin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Thymucin with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Astragalus (Astragalus membranaceus) root extract
Antidiabetes Drugs
Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.
Cyclophosphamide
Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.
Immunosuppressants
Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.
Lithium
Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.
Brand information
Manufacturer and brand details for Thymucin, from the product label.
Integrative Therapeutics
See all Integrative Therapeutics products- Name
- Integrative Therapeutics, LLC
- City
- Green Bay
- State
- WI
- ZipCode
- 54311
- Phone Number
- 800.931.1709
- Web Address
- integrativepro.com
Thymucin by Integrative Therapeutics: Common Questions
Does Thymucin by Integrative Therapeutics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take Thymucin while pregnant or breastfeeding?
What is astragalus, and why is it in this product?
What side effects has astragalus caused?
Why can't you check thymus powder for interactions?
Does Thymucin have fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Thymucin’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographAstragalus
Interacts with 208 drugsAstragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While early studies are interesting, strong h...
Read the full Astragalus monograph →Sources & How We Checked
Thymucin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 31 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Astragalus 13 references
- Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
- Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
- Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
- Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
- Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
- Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
- Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
- Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
- Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
- Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
- Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
- Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
- Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC