Thyroid Calming Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Thyroid Calming against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Thyroid Calming is a dietary supplement by Herb Pharm with 4 active ingredients. Its ingredients are commonly taken for mild overactive thyroid symptoms, heart palpitations and rapid heartbeat, anxiety and restlessness.Based on those ingredients, 273 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lemon Balm Aerial Parts Extract, Fresh, Undried, Motherwort Flowering Aerial Parts Extract, Bugleweed flowering aerial parts extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Thyroid Calming by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Thyroid Calming by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Thyroid Calming by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Thyroid Calming contains four active ingredients. Bugleweed (flowering aerial parts extract) is traditionally used for thyroid concerns.
Cactus grandiflorus, or cereus (fresh stem extract), is included for its effects on the heart and nervous system. Lemon balm (fresh aerial parts extract) is added for stress and mood support.
Motherwort (flowering aerial parts extract) completes the blend for additional cardiovascular and calming effects. The product comes in liquid form and contains cane alcohol, water, and glycerin as inactive ingredients.
Does it work?
Moderate evidence
The evidence for this product's ingredients is mixed. Bugleweed, cactus grandiflorus, and motherwort all lack reliable evidence to support their use for hyperthyroidism, the main condition someone might reach for this product for — the data rates them as insufficient evidence.
Lemon balm is possibly effective for stress and cold sores, which may play a supporting role. Overall, the scientific backing for using this product specifically for thyroid support is not established in our data.
How safe is it?
Well-documented data
Lemon balm is generally well tolerated for short-term use in healthy adults, though long-term safety isn't well studied. A small number of people report dizziness or sedation, though it doesn't happen more often than with placebo.
Motherwort and bugleweed are tolerated short-term, but human safety data are limited. Motherwort in amounts over 3 grams can cause uterine bleeding, and it and motherwort leaves may cause contact dermatitis or photosensitivity.
Fresh cereus juice may cause mouth burning, nausea, vomiting, or diarrhea in some people. Bugleweed is rated likely unsafe in pregnancy because it may affect hormone levels.
Lemon balm is best avoided in pregnancy unless your doctor advises otherwise — the data isn't enough to know either way. Motherwort is rated likely unsafe in pregnancy because it's traditionally thought to stimulate the uterus.
Bugleweed should not be used while breastfeeding because it may reduce milk production. Lemon balm and motherwort should be avoided while breastfeeding due to insufficient safety data.
Cereus has no reliable safety data for pregnancy or breastfeeding.
Meds to double-check
Moderate interaction found
Before you take this, double-check with your pharmacist or doctor if you're on thyroid hormone replacement (like levothyroxine), any CNS depressants (sedatives, sleep aids, anxiety meds, or pain relievers that cause drowsiness), digoxin (a heart medication), or MAOIs (older antidepressants). All of these have documented interactions with ingredients in this product.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product is aimed at people interested in natural thyroid support, but the evidence for its main ingredients in that role is not established. If you take thyroid hormones, CNS depressants, digoxin, or MAOIs, you need to check your exact medications before starting.
Talk to your pharmacist or doctor first — especially if you're pregnant, breastfeeding, or taking any prescription drugs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Thyroid Calming, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090800000768 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2025 |
| DSLD ID | 336578 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Thyroid Calming by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 654 mg | -- |
| Bugleweed flowering aerial parts extract | 0 NP | -- |
| Cactus grandiflorus Stem Extract, Fresh, Undried | 0 NP | -- |
| Lemon Balm Aerial Parts Extract, Fresh, Undried | 0 NP | -- |
| Motherwort Flowering Aerial Parts Extract | 0 NP | -- |
Other ingredients: Cane Alcohol, Water, Distilled, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 4 times per day. Best taken between meals.
Precautions
Caution: Seek expert medical advice before taking during pregnancy or nursing.
Not for use in hypothyroidism or thyroid enlargement.
Use with caution in persons taking thyroid & heart medications.
Keep out of the reach of children
Storage
Store away from heat & light
Formulation
System restoration Endocrine
Gluten-free
FDA Statement of Identity
Herbal Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Thyroid Calming by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Thyroid Calming by Herb Pharm
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container42 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Other (inactive) ingredients: Cane Alcohol, Water, Distilled, Glycerin. These complete the product’s ingredient list but are not active constituents.
Thyroid Calming by Herb Pharm Drug Interactions
HelloPharmacist Interaction Report
Thyroid Calming by Herb Pharm contains four active ingredients, and together they interact with a significant number of medications.
The most serious concern is bugleweed, which moderately interacts with thyroid hormones — it may block the conversion of T4 to T3, potentially reducing how well your thyroid replacement therapy works.
Read the full breakdown — every affected drug type, severity by severity
Lemon balm and motherwort both interact moderately with CNS depressants (sedatives, sleep aids, anxiety medications, pain relievers that cause drowsiness). Using them together may add up to extra drowsiness or sedation.
Lemon balm also moderately interacts with thyroid hormone medications by a different mechanism — it may interfere with how your body responds to TSH, the hormone that signals your thyroid.
Cactus grandiflorus (cereus) moderately interacts with digoxin, a heart medication, potentially strengthening its effects on your heart. It also moderately interacts with MAOIs, a class of older antidepressants, because of tyramine content.
Altogether, these interactions span 273 individual medications. Before you start this product, use the medication checker below to look up your exact drugs.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Thyroid Calming?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Thyroid Calming interact with 273 drugs. Click any drug to see the details.
4 of the 4 ingredients in Thyroid Calming interact with drugs. Each result below shows which ingredient is responsible. Lemon Balm Aerial Parts Extract, Fresh, Undried Motherwort Flowering Aerial Parts Extract Bugleweed flowering aerial parts extract Cactus grandiflorus Stem Extract, Fresh, Undried
AcepromazineAtravet
How Acepromazine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acepromazine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acepromazine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Butalbital, Codeine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Caffeine, Codeine interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Caffeine, Codeine, Salicylamide interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Chlorzoxazone, Codeine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Chlorzoxazone, Codeine interactionAcetaminophen, CodeineTylenol No.3, Tylenol w/ Codeine
How Acetaminophen, Codeine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Codeine interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Codeine interactionAcetaminophen, Codeine, DoxylamineMersyndol
How Acetaminophen, Codeine, Doxylamine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Codeine, Doxylamine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Codeine, Doxylamine interactionAcetaminophen, Codeine, MethocarbamolAcetaminophen, Codeine, Methocarbamol, Robaxacet 8
How Acetaminophen, Codeine, Methocarbamol interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Codeine, Methocarbamol interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Codeine, Methocarbamol interactionAcetaminophen, Dichloralantipyrine, IsomethepteneAmidrine, Midchlor, Migquin, Migratine
How Acetaminophen, Dichloralantipyrine, Isometheptene interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Dichloralantipyrine, Isometheptene interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Dichloralantipyrine, Isometheptene interactionAcetaminophen, Dichloralphenazone, IsomethepteneMidrin
How Acetaminophen, Dichloralphenazone, Isometheptene interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Dichloralphenazone, Isometheptene interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Dichloralphenazone, Isometheptene interactionAcetaminophen, Dichlorophenazone, IsometheptaneIsocom
How Acetaminophen, Dichlorophenazone, Isometheptane interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Dichlorophenazone, Isometheptane interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Dichlorophenazone, Isometheptane interactionAcetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Diphenhydramine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Hydrocodone interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Hydrocodone interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Meperidine interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Meperidine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Oxycodone interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Oxycodone interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Pentazocine interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Pentazocine interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetaminophen, Propoxyphene interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetaminophen, Propoxyphene interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Acetazolamide interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Acetazolamide interactionAlfentanilAlfenta
How Alfentanil interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Alfentanil interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Alfentanil interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Alprazolam interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Alprazolam interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAminoglutethimideCytadren
How Aminoglutethimide interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Motherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Aminoglutethimide interactionLemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Aminoglutethimide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with Thyroid Calming — through 2 ingredients. Tap an ingredient for the detail:
Lemon Balm Aerial Parts Extract, Fresh, UndriedCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Read the full Lemon Balm Aerial Parts Extract, Fresh, Undried + Aminophylline, Amobarbital, Ephedrine interactionMotherwort Flowering Aerial Parts ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Read the full Motherwort Flowering Aerial Parts Extract + Aminophylline, Amobarbital, Ephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Thyroid Calming with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Lemon Balm Aerial Parts Extract, Fresh, Undried
Cns Depressants
Theoretically, concomitant use of lemon balm might have additive effects with CNS depressant drugs.
Lemon balm seems to have CNS depressant activity in animals and in humans.
Thyroid Hormone
Theoretically, lemon balm might interfere with thyroid hormone replacement therapy.
In vitro, constituents of lemon balm extract bind to thyroid stimulating hormone (TSH), preventing TSH receptor-binding and leading to the inhibition of TSH-stimulated adenylate cyclase activity. In animals, lemon balm extract has been shown to decrease levels of circulating TSH and inhibit thyroid secretion.
Motherwort Flowering Aerial Parts Extract
Cns Depressants
Theoretically, taking motherwort concomitantly with other CNS depressants may increase the risk of sedation.
Motherwort has been reported to cause CNS depression and sedation.
Bugleweed flowering aerial parts extract
Thyroid Hormone
Theoretically, bugleweed may alter thyroid function.
Concomitant use of bugleweed may reduce the effects of thyroid hormones by blocking peripheral conversion of thyroxine (T4) to triiodothyronine (T3).
Cactus grandiflorus Stem Extract, Fresh, Undried
Digoxin (Lanoxin)
Cereus may potentiate the actions of cardiac glycosides and may enhance the effect of other cardiac drugs.
Monoamine Oxidase Inhibitors (Maois)
Theoretically, excessive doses of cereus may interact with MAOIs, because of the tyramine content.
Brand information
Manufacturer and brand details for Thyroid Calming, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Thyroid Calming by Herb Pharm: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Thyroid Calming is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Thyroid Calming’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bugleweed
Interacts with 16 drugsBugleweed is a traditional herb most often used for mild overactive thyroid symptoms and the rapid heartbeat that can come with it, but high-quality human evidence is very limited. Because i...
Read the full Bugleweed monograph → Herb & supplement monographCereus
Interacts with 10 drugsCereus (often called night-blooming cereus) is a cactus traditionally used in folk and homeopathic medicine for heart-related complaints like palpitations. High-quality human evidence suppor...
Read the full Cereus monograph → Herb & supplement monographLemon Balm
Interacts with 264 drugsLemon balm is a gentle, lemon-scented mint-family herb traditionally used to ease stress, support sleep, and calm digestion, and topically for cold sores. Early studies are promising but gen...
Read the full Lemon Balm monograph → Herb & supplement monographMotherwort
Interacts with 248 drugsMotherwort is a traditional herb in the mint family long used for anxiety, heart palpitations, and women's reproductive complaints, but solid human evidence is very limited. It should be avo...
Read the full Motherwort monograph →Sources & How We Checked
Thyroid Calming's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 25 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bugleweed 4 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Cereus 3 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Fetrow CW, Avila JR. Professional's Handbook of Complementary & Alternative Medicines. 1st ed. Springhouse, PA: Springhouse Corp., 1999.
Lemon Balm 12 references
- Wolbling RH, Leonhardt K. Local therapy of herpes simplex with dried extract from Melissa officinalis. Phytomedicine 1994;1:25-31.
- Akhondzadeh S, Noroozian M, Mohammadi M, et al. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry 2003;74:863-6. PubMed
- Kennedy DO, Scholey AB, Tildesley NT, et al. Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm). Pharmacol Biochem Behav 2002;72:953-64. PubMed
- Albrecht M, Berger W, Laux P, Schmidt U, et al. Psychopharmaka und Verkehrssicherheit. Der Einfluß von Euvegal® - Dragees forte auf die Fahrtüchtigkeit und Kombinationswirkungen mit Alkohol Z Allg Med 1995;71:1215-25.
- Herberg, KW. Nebenwirkungen pflanzlicher Beruhigungsmittel/ Leistung und Befinden nach Einnahme einer Baldrian-Hopfen-Kombination. Z.Allg Med 1996;72:234-240.
- Soulimani R, Fleurentin J, Mortier F, et al. Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse. Planta Med. 1991 Apr;57:105-9.
- Sourgens H, Winterhoff H, Gumbinger HG, et al. Antihormonal effects of plant extracts. TSH- and prolactin-suppressing properties of Lithospermum officinale and other plants. Planta Med. 1982 Jun;45:78-86. DOI
- Auf'mkolk M, Ingbar JC, Amir SM, et al. Inhibition by certain plant extracts of the binding and adenylate cyclase stimulatory effect of bovine thyrotropin in human thyroid membranes. Endocrinology. 1984 Aug;115:527-34. PubMed
- Santini F, Vitti P, Ceccarini G, et al. In vitro assay of thyroid disruptors affecting TSH-stimulated adenylate cyclase activity. J Endocrinol Invest. 2003 Oct;26:950-5. PubMed
- Alijaniha F, et al. Heart palpitation relief with Melissa officinalis leaf extract: double blind, randomized, placebo controlled trial of efficacy and safety. J Ethnopharmacol. 2015;164:378-384. doi: 10.1016/j.jep.2015.02.007. Epub 2015 Feb 11. PubMed
- Araj-Khodaei M, Noorbala AA, Yarani R, et al. A double-blind, randomized pilot study for comparison of Melissa officinalis L. and Lavandula angustifolia Mill. with Fluoxetine for the treatment of depression. BMC Complement Med Ther. 2020;20(1):207. PubMed
- Kucuk U, Pham M, Raza Raja MH, Saad Shaukat MH, Clark R. Transient complete atrioventricular block associated with herbal supplement use. S D Med 2023;76(7):311-313.
Motherwort 6 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Wojtyniak K, Szymanski M, Matlawska I. Leonurus cardiaca L. (motherwort): a review of its phytochemistry and pharmacology. Phytother Res 2013;27(8):1115-20.
- Xia WT, Zhou H, Wang Y, et al. Motherwort injection in preventing post-abortion hemorrhage after induced abortion: A multi-center, prospective, randomized controlled trial. Explore (NY). 2019. pii: S1550-8307(19)30447-1. PubMed
- Cao Shan DOSOGC, Zhang W, Zhao Z, et al. Post-marketing safety surveillance and reevaluation of Motherwort injection: A clinical study of 10 094 cases. J Tradit Chin Med. 2018 Aug;38(4):625-635. DOI
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC