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Dietary supplement

TLIP Ingredients & Drug Interactions

by Genestra Brands

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

TLIP is a dietary supplement by Genestra Brands with 1 active ingredient. Its ingredients are commonly taken for anemia and low iron, vitamin b12 support, general energy and fatigue.Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Bovine (Bos taurus) Liver. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of TLIP by Genestra Brands

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

TLIP contains one active ingredient: bovine liver extract — a concentrate derived from cow liver. The product also includes two inactive ingredients (hypromellose and silica), which are capsule materials and a flow agent.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Liver Extract's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: liver health support.
  • We looked for evidence on: Hepatitis C, liver function, liver disease, hepatic health.
  • The closest evidence on file: Liver Extract is rated "Insufficient Reliable Evidence To Rate" for Hepatitis C (Natural Medicines).

The evidence for liver extract is limited. For chronic fatigue syndrome, the data suggests it's possibly ineffective.

For hepatitis C, we don't have enough reliable evidence to say whether it works or not. If either condition is why you're considering this, talk with your doctor about what the science actually supports.

The evidence, ingredient by ingredient Liver Extract

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

No adverse reactions have been reported with liver extract, but a thorough safety study hasn't been done, so gaps remain. The real concerns are the source and quality of the raw material.

Liver extract can contain very high levels of vitamin A and iron — both of which can cause problems at high doses or with long-term use. There's also a theoretical risk of contamination from diseased animals or, in rare cases, BSE (bovine spongiform encephalopathy, or mad cow disease), though no human cases from contaminated liver extract have been reported.

Until more is known, check with your doctor before using, especially if you're pregnant — high vitamin A in pregnancy may harm a developing baby.

Side effects, ingredient by ingredient Liver Extract

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Liver Extract.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before taking TLIP if you use warfarin (Coumadin) — the vitamin K in liver extract may reduce its blood-thinning effect. Also double-check if you take any iron supplements or iron-containing medications, since liver extract itself contains iron and the combination could raise your total intake.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

TLIP is a single-ingredient liver extract supplement with minor documented interactions mainly affecting warfarin and iron supplements. It's generally low-risk for healthy adults eating food amounts, but this product delivers concentrated doses, so source quality and vitamin A and iron levels matter.

If you take warfarin or iron supplements, or you're pregnant or nursing, talk with your pharmacist or doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about TLIP, straight from the product label.

Brand Genestra Brands
Barcode (UPC) 88319612410
Net contents 60 Vegetable Capsule(s)
Market status On market
Date entered into DSLD Jan 25, 2016
DSLD ID 56093
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for TLIP by Genestra Brands, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
88319612410
IngredientAmount% DV
Bovine (Bos taurus) Liver550 mg--

Other ingredients: Hypromellose, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Adult Dose: Take one capsule three times daily with meals or as recommended by your healthcare practitioner. Take a few hours before or after taking other medication.

Precautions

Risk Information: For adult use only.

If you are pregnant or breastfeeding, do not use.

Quality Assurance: Safety-sealed for your protection and for product freshness. Do not use if outer seal is missing or broken.

Formulation

Guaranteed to contain no added wheat, starch, yeast, gluten, corn, soy, sodium, sugar, artificial coloring or flavoring, antimicrobial preservatives or dairy products. The capsules are made from 100% pure vegetable sources, free of preservatives and additives.

Storage

Store in a cool, dry place.

FDA Statement of Identity

LIVER SUPPLEMENT

General

V1.0 317

Seals/Symbols

Seroyal

See for yourself

TLIP by Genestra Brands label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in TLIP by Genestra Brands

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Bovine (Bos taurus) Liver

Interacts with
3 drugs
550 mg per serving

Liver extract is a dried or concentrated form of animal liver that is naturally rich in iron, vitamin B12, vitamin A, and other nutrients. It was once...

Bovine (Bos taurus) Liver monograph & interactions

Other (inactive) ingredients: Hypromellose, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

TLIP by Genestra Brands Drug Interactions

Want to check YOUR meds against TLIP?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in TLIP with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bovine (Bos taurus) Liver2 drug types · 3 drugs

Iron

Liver extract can contain heme iron. Taking liver extract with iron-containing medications or supplements may increase total iron intake and could increase the risk of gastrointestinal adverse effects or excessive iron accumulation. The risk is greater with high doses, prolonged use, or in individuals with hemochromatosis or another iron-overload disorder. Review the iron content of the liver extract and the total elemental iron dose. Avoid unnecessary duplicate iron supplementation and consider monitoring ferritin and transferrin saturation when clinically appropriate.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Liver extract products may contain small and variable amounts of vitamin K. Theoretically, starting, stopping, or substantially changing the amount of liver extract used could reduce the anticoagulant effect of warfarin and lower the INR. However, this interaction has not been directly studied or reported in humans, and the vitamin K content of liver extract products is generally not standardized. Consider monitoring the INR after a meaningful change in liver extract use.

Likelihood Possible Evidence C
The maker

Brand information

Manufacturer and brand details for TLIP, from the product label.

Genestra Brands

Name
Seroyal USA
City
Pittsburgh
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Web Address
seroyal.com
Pharmacist Counseling Corner

TLIP by Genestra Brands: Common Questions

Does TLIP by Genestra Brands interact with any medications?
Yes. Based on its ingredients, TLIP has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
TLIP contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is bovine liver extract, and why is it in this supplement?
It's a concentrate made from cow liver. Traditionally it's been used as a nutritional support supplement, though the evidence for most uses is weak or absent. We hold data on two uses — chronic fatigue syndrome (possibly ineffective) and hepatitis C (insufficient evidence).
Is it safe if I'm pregnant or breastfeeding?
The safety data on this product during pregnancy and breastfeeding aren't well established. Liver extract can contain very high vitamin A, which may harm a developing baby. Talk with your doctor before using it during pregnancy or lactation.
Can I take this with warfarin?
Not without checking first. Liver extract contains variable amounts of vitamin K, which can interfere with how warfarin works and lower your INR. The interaction hasn't been studied directly in people, but the risk is real enough that you should run this by your pharmacist or doctor before starting.
What are the side effects?
No adverse reactions have been reported, but a thorough safety evaluation hasn't been done. The main concern isn't a typical 'side effect' — it's the source and quality of the raw animal material and the risk of very high vitamin A and iron intake with regular use.
Does liver extract really work for chronic fatigue?
The evidence suggests it's possibly ineffective for chronic fatigue syndrome. If that's why you're considering it, talk with your doctor about treatments with stronger evidence behind them.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if TLIP is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

TLIP label
Sources

Sources & How We Checked

TLIP's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Liver Extract 4 references
  1. Lewis CJ. Letter to reiterate certain public health and safety concerns to firms manufacturing or importing dietary supplements that contain specific bovine tissues. FDA. Available at: www.cfsan.fda.gov/~dms/dspltr05.html.
  2. Kaslow JE, Rucker L, Onishi R. Liver extract-folic acid-cyanocobalamin vs placebo for chronic fatigue syndrome. Arch Intern Med 1989;149:2501-3. DOI
  3. Ebinuma, H., Saito, H., Tada, S., Masuda, T., Kamiya, T., Nishida, J., Yoshioka, M., and Ishii, H. Additive therapeutic effects of the liver extract preparation mixture adelavin-9 on interferon-beta treatment for chronic hepatitis C. Hepatogastroenterolog
  4. Saito, H., Ebinuma, H., Tada, S., Tsunematsu, S., Atsukawa, K., Masuda, T., Tsuchiya, M., and Ishii, H. Enhancing effect of the liver extract and flavin adenin dinucleotide mixture on anti-viral efficacy of interferon in patients with chronic hepatitis C. PubMed

See these in context on the Liver Extract monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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