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Dietary supplement

Tongkat Ali Extract LJ100-Longjack 100 mg Ingredients & Drug Interactions

by Double Wood Supplements

Tongkat Ali Extract LJ100-Longjack 100 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Tongkat Ali Extract LJ100-Longjack 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Tongkat Ali Extract LJ100-Longjack 100 mg is a dietary supplement by Double Wood Supplements with 1 active ingredient. Its ingredients are commonly taken for low testosterone or low libido in men, male fertility support, athletic performance and muscle strength.Based on those ingredients, 248 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are LJ100 Eurycoma longifolia extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements

Ask about any prescription or over-the-counter medication and we check it for interactions with Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 17, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: LJ100 Eurycoma longifolia extract at 100 mg per capsule. Eurycoma longifolia, also called Tongkat Ali or Longjack, is a plant extract traditionally used to support male sexual function and general vitality.

The product is filled out with non-GMO rice flour and housed in a vegetable cellulose capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: libido enhancement and cortisol reduction.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual desire, Age-related testosterone deficiency, stress reduction, mood support, male sexual function.
  • The strongest evidence on file: Eurycoma Longifolia is rated "Possibly Effective" for Sexual desire (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Age-related testosterone deficiency.

The evidence we hold shows Eurycoma longifolia is possibly effective for sexual desire. For athletic performance, the data suggests it's probably ineffective.

For back pain, osteoporosis, and diabetes, there isn't enough reliable evidence to rate how well it works. If sexual desire support is what you're after, there's some clinical backing; for other uses, the picture is unclear.

The evidence, ingredient by ingredient Eurycoma Longifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use is generally well tolerated in studies, though long-term safety and the consistency of different products on the market aren't well established. There's a caution worth knowing: the extract can increase testosterone levels.

If that pushes your testosterone beyond the normal range, you may develop testosterone-related side effects such as acne, insulin resistance, or liver effects. Because of possible hormonal effects and limited safety data, avoid it during pregnancy and breastfeeding.

Side effects, ingredient by ingredient Eurycoma Longifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Eurycoma Longifolia.
  • The most serious interaction on file is rated Moderate.
  • For scale: 248 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take propranolol (Inderal) for your heart or blood pressure, this is the biggest one to check with your doctor or pharmacist first—the extract can reduce how well it works. You should also double-check any medications metabolized by CYP1A2, CYP2C19, or CYP2A6 enzymes in your liver, and if you're on testosterone replacement therapy, because the extract may raise testosterone further.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Tongkat Ali is an option if you're interested in support for sexual desire and don't take propranolol or other medications that depend on those liver enzymes. If you're on any prescription medication—especially heart drugs, testosterone therapy, or anything your liver processes—talk it over with your doctor or pharmacist before you start.

Long-term safety isn't as well studied, so this is more of a short-term support supplement.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tongkat Ali Extract LJ100-Longjack 100 mg, straight from the product label.

Brand Double Wood Supplements
Barcode (UPC) 859793007211
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 241953
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
859793007211
IngredientAmount% DV
LJ100 Eurycoma longifolia extract100 mg--

Other ingredients: Non GMO Rice flour, Vegetable Cellulose Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Tongkat Ali Extract is an herbal extract that has demonstrated significant libido enhancing effects as well as reducing cortisol and improving one's sense of subjective wellbeing. Some studies suggest Tongkat Ali Extract may also reduce anxiety. Our product is the patented LJ100 version which contains 22% Bioactive Eurypeptides and 40% Glyco Saponins.

100mg per capsule

Suggested/Recommended/Usage/Directions

Suggested Use: As a supplement for libido and cotrisol reduction take one to three 100 mg capsules per day.

Storage

Storage: Store in a cool, dark place. Do not freeze or expose to moisture or heat above room temperature.

Precautions

Warning: Consult your physician before use if you are taking any medications. Don't use Tongkat Ali extract if you are pregnant or nursing.

Discontinue use and consult your doctor immediately if any adverse reactions occur.

Do not take Tongkat Ali Extract and operate heavy machinery until you know how it will affect you.

Keep out of reach of children.

Brand IP Statement(s)

Lj100 is the registered trademark of HP Ingredients. LJ100 US Patent 7,132,117 Bioactive Fraction of Eurycoma longifolia

Formulation

Improves libido Reduces cortisol

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Tongkat Ali Extract LJ100-Longjack 100 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

LJ100 Eurycoma longifolia extract

Interacts with
248 drugs
100 mg per serving Form: Bioactive Eurypeptides, Glyco Saponins

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small huma...

LJ100 Eurycoma longifolia extract monograph & interactions

Other (inactive) ingredients: Non GMO Rice flour, Vegetable Cellulose Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements Drug Interactions

Want to check YOUR meds against Tongkat Ali Extract LJ100-Longjack 100 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
248Drugs
3 Moderate 245 Minor

Ingredients driving the most interactions

LJ100 Eurycoma longifolia extract 248

Individual Drug Interactions

The ingredients in Tongkat Ali Extract LJ100-Longjack 100 mg interact with 248 drugs. Click any drug to see the details.

1 of the 1 ingredient in Tongkat Ali Extract LJ100-Longjack 100 mg interact with drugs. Each result below shows which ingredient is responsible. LJ100 Eurycoma longifolia extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Tongkat Ali Extract LJ100-Longjack 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

LJ100 Eurycoma longifolia extract5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
LJ100 Eurycoma longifolia extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Tongkat Ali Extract LJ100-Longjack 100 mg, from the product label.

Double Wood Supplements

See all Double Wood Supplements products
Name
Double Wood LLC
Street Address
3510 Scotts Ln Ste 219
City
Philadelphia
State
PA
ZipCode
19129-1573
Web Address
www.doublewoodsupplements.com
Pharmacist Counseling Corner

Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements: Common Questions

Does Tongkat Ali Extract LJ100-Longjack 100 mg by Double Wood Supplements interact with any medications?
Yes. Based on its ingredients, Tongkat Ali Extract LJ100-Longjack 100 mg has a known interaction with 248 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tongkat Ali Extract LJ100-Longjack 100 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No—the safety data isn't there, and because the extract can affect hormone levels, it's best to avoid it both during pregnancy and while breastfeeding. Talk with your doctor or pharmacist if you have questions about what's safe for you.
Does this actually improve sexual desire?
The evidence shows it's possibly effective for sexual desire, so there is some clinical backing. For other uses like athletic performance, the evidence suggests it probably won't help, and for back pain, osteoporosis, and diabetes, we don't have enough reliable data to say one way or the other.
What are the side effects?
In short-term studies, it's generally well tolerated. The main risk is if it raises your testosterone too high—that can lead to acne, insulin resistance, liver effects, and other testosterone-related issues. Long-term safety isn't as well studied.
Can I take this long-term?
The studies we have focus on short-term use, and long-term safety isn't well established. Product quality can also vary between brands. If you're thinking about using it regularly, check with your doctor or pharmacist first.
What's LJ100?
LJ100 is a standardized extract of Eurycoma longifolia root, also called Tongkat Ali. It's a plant extract that's been studied for its effects on male sexual function and testosterone levels.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tongkat Ali Extract LJ100-Longjack 100 mg label
Go deeper

The Full Monographs Behind Tongkat Ali Extract LJ100-Longjack 100 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph →
Sources

Sources & How We Checked

Tongkat Ali Extract LJ100-Longjack 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Eurycoma Longifolia 4 references
  1. Salman SA, Amrah S, Wahab MS, et al. Modification of propranolol's bioavailability by Eurycoma longifolia water-based extract. J Clin Pharm Ther 2010;35:691-6. PubMed
  2. Tambi MI, Imran MK, Henkel RR. Standardised water-soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late-onset hypogonadism? Andrologia 2011 Jun 15. doi: 10.1111/j.1439-0272.2011.01168.x. [Epub ahead of pri PubMed
  3. Han YM, Kim IS, Rehman SU, Choe K, Yoo HH. In vitro evaluation of the effects of Eurycoma longifolia extract on CYP-mediated drug metabolism. Evid Based Complement Alternat Med 2015;2015:631329.
  4. Chinnappan SM, George A, Pandey P, Narke G, Choudhary YK. Effect of Eurycoma longifolia standardised aqueous root extract-Physta ® on testosterone levels and quality of life in ageing male subjects: a randomised, double-blind, placebo-controlled multicent

See these in context on the Eurycoma Longifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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