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Dietary supplement

Tribulus Fruit 10% Extract Powder Ingredients & Drug Interactions

by TerraVita Premium Collection

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Tribulus Fruit 10% Extract Powder is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for low libido and sexual function, athletic performance and muscle building, testosterone support.Based on those ingredients, 259 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Tribulus Fruit Extract, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Tribulus Fruit 10% Extract Powder by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains one active ingredient: tribulus fruit extract (standardized to 10% extract strength). There are no inactive fillers or other ingredients listed.

Tribulus is a plant fruit traditionally used in herbal medicine. The extract concentrates its active compounds into powder form for easy mixing or capsule filling.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Tribulus's overall clinical evidence instead.

Moderate

Some clinical evidence supports Tribulus for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Sexual dysfunction — rated "Possibly Effective" (Natural Medicines).

Tribulus is rated possibly effective for sexual dysfunction — meaning there's some research support, but the evidence isn't rock-solid yet and more study is needed. For athletic performance, the evidence suggests it's possibly ineffective.

For benign prostate enlargement (benign prostatic hyperplasia, or BPH), we don't have enough reliable evidence to rate it one way or the other.

The evidence, ingredient by ingredient Tribulus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Tribulus is generally well tolerated short-term in healthy adults, but quality data on long-term use is thin. Gastrointestinal side effects like belly pain, cramping, nausea, vomiting, diarrhea, and constipation can occur, though in one study they showed up at similar rates in both tribulus and placebo groups.

Rare serious effects including liver and kidney injury, seizures, and chronic painful erection have been reported. One case involved someone drinking 2 liters of tribulus water daily for two days and developing weakness, seizures, liver inflammation, and acute kidney injury (they improved after dialysis and stopping the supplement).

Avoid tribulus during pregnancy — it may affect hormones and safety isn't established. Also avoid it while breastfeeding due to lack of safety data.

Side effects, ingredient by ingredient Tribulus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Tribulus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 259 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with us if you take blood pressure medications, diabetes medications, or lithium before you start this product. All three carry Moderate risk of interaction: blood pressure and blood sugar could drop too low, and lithium levels could rise dangerously.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Tribulus may help with sexual dysfunction, though the evidence is still building. If you take blood pressure medication, diabetes medication, or lithium, talk with us before starting this — the interactions are real and could affect how well your drugs work.

Stick to short-term use, watch for stomach upset, and let us know if you're pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Tribulus Fruit 10% Extract Powder, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435215460
Net contents 1 Ounce(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 284687
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Tribulus Fruit 10% Extract Powder by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.25 Teaspoon(s)
Maximum serving Sizes:
0.25 Teaspoon(s)
Servings per container
28
UPC/BARCODE
064435215460
IngredientAmount% DV
Tribulus Fruit Extract, Powder1000 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Stir 1/4 of a teaspoon into a glass of water and consume 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Tribulus Fruit 10% Extract Powder by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Tribulus Fruit 10% Extract Powder by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.25 Teaspoon(s) Dosage formPowder Servings per container28 Amounts shown are per serving.

Tribulus Fruit Extract, Powder

Interacts with
259 drugs
1000 mg per serving

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims...

Tribulus Fruit Extract, Powder monograph & interactions
Interaction report

Tribulus Fruit 10% Extract Powder by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Tribulus Fruit 10% Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
259Drugs
259 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Tribulus Fruit 10% Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Tribulus Fruit Extract, Powder3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Tribulus Fruit 10% Extract Powder, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Tribulus Fruit 10% Extract Powder by TerraVita Premium Collection: Common Questions

Does Tribulus Fruit 10% Extract Powder by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Tribulus Fruit 10% Extract Powder has a known interaction with 259 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Tribulus Fruit 10% Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does tribulus really work for sexual dysfunction?
The evidence says possibly. Studies show some benefit, but research is still ongoing and results vary. It's worth a try if you're interested, but manage your expectations and talk with your doctor if you're on other medications first.
Can I take this if I'm pregnant or breastfeeding?
No — the safety data advises against it. Tribulus may affect your hormones during pregnancy and we don't have enough safety information for breastfeeding. Talk with your doctor or midwife about what's safe for you.
What side effects should I watch for?
Most people tolerate it well short-term. Stomach upset — cramping, nausea, diarrhea — can happen, though studies show it's no worse than placebo sometimes. Serious effects like liver or kidney injury and seizures are rare but have been reported, especially at very high doses. Stop and contact us if anything unusual happens.
Why do I need to check my blood pressure or diabetes medication with you?
Tribulus can lower both blood pressure and blood sugar on its own. Add it to medication that already does the same thing, and you risk levels dropping dangerously low. Your pharmacist can review your specific drugs and tell you whether it's safe to combine.
Is this just tribulus, or are there other ingredients?
Just tribulus fruit extract — no fillers or other actives. That makes it straightforward, but it also means you're getting the full effect of the herb.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Tribulus Fruit 10% Extract Powder is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Tribulus Fruit 10% Extract Powder label
Go deeper

The Full Monographs Behind Tribulus Fruit 10% Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Tribulus Fruit 10% Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tribulus 10 references
  1. Sharifi AM, Darabi R, Akbarloo N. Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Sci 2003;73:2963-71. PubMed
  2. Walker D, Bird A, Flora T, O'Sullivan B. Some effects of feeding Tribulus terrestris, Ipomoea lonchophylla and the seed of Abelmoschus ficulneus on fetal development and the outcome of pregnancy in sheep. Reprod Fertil Dev 1992;4:135-44. PubMed
  3. Al-Ali M, Wahbi S, Twaij H, Al-Badr A. Tribulus terrestris: preliminary study of its diuretic and contractile effects and comparison with Zea mays. J Ethnopharmacol 2003;85:257-60. PubMed
  4. Tabakova, P., Dimitrov, M., Ognyanov, K., and et al. Clinical study of Tribestan in females with endocrine sterility. Documentation for Registration (unpublished) 1999.
  5. Akhtari E, Raisi F, Keshavarz M, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. Daru 2014;22:40. PubMed
  6. Ryan M, Lazar I, Nadasdy GM, et al. Acute kidney injury and hyperbilirubinemia in a young male after ingestion of Tribulus terrestris. Clin Nephrol 2015;83(3):177-83. PubMed
  7. Postigo S, Lima SM, Yamada SS, et al. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016;38(3):140-6. PubMed
  8. Talasaz AH, Abbasi MR, Abkhiz S, Dashti-Khavidaki S. Tribulus terrestris-induced severe nephrotoxicity in a young healthy male. Nephrol Dial Tranplant 2010;25(11):3792-3. PubMed
  9. Samani NB, Jokar A, Soveid M, Heydari M, Mosavat SH. Efficacy of the hydroalcoholic extract of Tribulus terrestris on the serum glucose and lipid profile of women with diabetes mellitus: a double-blind randomized placebo-controlled clinical trial. J Evid
  10. Siddiqui MA, Itrat M, Mobeen A, Khan MI. Efficacy of khar-i-khasak (Tribulus terrestris Linn.) in prehypertension: a randomized, double-blind, placebo-controlled trial. J Complement Integr Med. 2021.

See these in context on the Tribulus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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