Tulsi Immune Breathe Cooling Cardamom Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Tulsi Immune Breathe Cooling Cardamom against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Tulsi Immune Breathe Cooling Cardamom is a dietary supplement by Organic India with 7 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and stomach upset, mouth ulcers and digestive complaints.Based on those ingredients, 1,383 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Licorice, Ginger, Pippali. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Tulsi Immune Breathe Cooling Cardamom by Organic India
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Tulsi Immune Breathe Cooling Cardamom by Organic India
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This product contains 8 ingredients, most of them herbs used in Ayurvedic and traditional medicine. The active ingredients include licorice (used for its potential anti-inflammatory effects and soothing properties), ginger (often used for nausea and digestion), cinnamon, cardamom, pushkarmool (also called elecampane), pippali (Indian long pepper), holy basil, and East Indian basil.
Together they're meant to support respiratory and immune function. The product contains no inactive fillers—what you see is the herb blend itself in tea-bag form.
Does it work?
Not established
The evidence for most ingredients in this blend is limited. Licorice has possibly effective ratings for canker sores and atopic dermatitis (eczema), but insufficient evidence for Addison disease and asthma.
Ginger shows possibly effective evidence for pregnancy-related nausea and vomiting, dysmenorrhea (painful menstruation), and osteoarthritis, though it was rated possibly ineffective for exercise soreness and chemotherapy-related nausea. Cinnamon, cardamom, pushkarmool, pippali, holy basil, and East Indian basil all lack established evidence for their listed uses in our data—most are rated insufficient to rate.
If you're taking this product for a specific health goal, talk with your doctor or pharmacist about whether the evidence supports that use.
How safe is it?
Well-documented data
Most of these ingredients are generally well tolerated in food and tea amounts. Licorice is the biggest safety concern: it's fine in small food amounts, but high doses or long-term use of the glycyrrhizin compound in licorice can cause serious problems with fluid retention, high blood pressure, and mineral imbalances.
Licorice is unsafe in pregnancy and should be avoided while breastfeeding. Ginger is likely safe in pregnancy in typical amounts but check with your doctor first; it's likely safe while breastfeeding.
Cinnamon and cardamom in food amounts are generally safe in pregnancy and lactation. Pushkarmool (elecampane) should be avoided during pregnancy and breastfeeding due to insufficient safety data.
Holy basil and East Indian basil are possibly unsafe in pregnancy and should be avoided while breastfeeding. Common side effects from these herbs can include mild gastrointestinal discomfort, nausea, and headache.
Some people may experience allergic contact dermatitis from topical exposure to any of these herbs.
Meds to double-check
Moderate interaction found
If you take a heart medication like digoxin, a blood thinner like warfarin, diabetes drugs, a sedative or sleeping pill, theophylline, propranolol, the antibiotic cyclosporine, or cancer medications, talk with your doctor or pharmacist before using this product. The licorice, ginger, and other herbs here have documented moderate interactions with these drug types.
No interactions are documented for cardamom among the ingredients we could check.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
This is an herbal tea blend rooted in traditional medicine, but the scientific evidence for most of its ingredients is thin. The real caution is licorice—it interacts with many medications and shouldn't be used long-term or in high doses without medical oversight.
If you take any prescription medication, especially heart drugs, blood thinners, or diabetes medicines, check with your doctor or pharmacist before starting this product. It's generally best to avoid during pregnancy and breastfeeding unless your healthcare provider says otherwise.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 8 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 16, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Tulsi Immune Breathe Cooling Cardamom, straight from the product label.
| Brand | Organic India |
|---|---|
| Net contents | 18 Infusion Bag(s); 1.27 Ounce(s); 36 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jun 16, 2022 |
| DSLD ID | 268207 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Tulsi Immune Breathe Cooling Cardamom by Organic India, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Licorice | 0 NP | -- |
| Ginger | 0 NP | -- |
| Cinnamon | 0 NP | -- |
| Cardamom | 0 NP | -- |
| Pushkarmool | 0 NP | -- |
| Pippali | 0 NP | -- |
| Holy Basil | 0 NP | -- |
| East Indian Basil | 0 NP | -- |
| Proprietary Organic Blend | 2 Gram(s) | -- |
| Organic Tulsi Blend | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
With clearing Pushkarmool
OU (Kosher)
Halal Mumbai India Halal Committee Registration No. 0854
Tulsi Immune Breathe is a novel blend, developed by experts. The best of Ayurvedic tradition comes together with flavorful, aromatic herbs to support respiratory health. Like the transition from inhale to exhale, this experiential blend begins with cooling cardamom and finishes with grounding, earthy, sweet licorice root. Holy basil
Tulsi - A legacy of good health Throughout India Tulsi is acclaimed as "The Queen of Herbs" and is revered as a sacred plant infused with healing powers. Tulsi (also known as Holy Basil) makes a delicious & nourishing herbal 'tea' offering abundant health benefits. Tulsi's life-enhancing qualities, repeatedly noted in ancient Indian scriptures dating back over 5,000 years, are now here for you to fully embrace. Children also love our Tulsi!
General Statements
Meet Tara Devi Rawat Healthy conscious living
Ayurvedic Medicine Mfg. Lic. No. A-2755 Individually wrapped for freshness
At the heart of Organic India is our commitment to be a living embodiment of love and consciousness in action. All our products promote health and happiness and are made with loving care. Healthy conscious living from soil to shelf ensures that each of our products is testimony to the flow of love, respect and connection between Mother Nature, our farmers and you. Organic regenerative agriculture regenerates healthy soil and ecosystems, restores vibrant health to the environment and produces the highest quality herbs. Partnering with family farmers provides a life of dignity to our local farmers and their families and revitalizes communities through fair wages, education and healthcare. When you choose Organic India products you actively participate in our mission to create a happier, healthier global environment. Organic India is committed to our earth seer standard, making choices that respect the health of our environment. Earth Seer Ethical, authentic, reliable, trustworthy, holistic, socially, environmentally, economically, responsible
We wish you a life of good health and happiness Scan QR code on bottom of box to learn about our beloved farmers.
Formulation
Respiratory support
Caffeine free
Certified Organic USDA Organic Control Union Certified NPOP/NAB/0010 www.controlunion.com Certified Organic by Control Union-CU 801983 Product produced and processed according to NPOP standard of India & USDA-NOP India Organic
Product of India For export to USA
Vegan Vegetarian
Gluten free
Uplifts mood Powerful adaptogen Promotes natural detoxification Immune system support Reduces stress Builds stamina Improves digestion and metabolism Provides antioxidants
FDA Statement of Identity
Herbal supplement
Seals/Symbols
USDA Organic Non GMO Project Verified nongmoproject.org Certified B Corporation
Halal Mumbai India Halal Committee Registration No. 0854 OU (Kosher) Control Union Certified India Organic
Precautions
If pregnant or nursing consult your physician prior to use.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Suggested/Recommended/Usage/Directions
Brewing Instructions: 1 Place one or more infusion bags in your cup 2 Add freshly boiled water 3 Cover and steep for 8-12 min Double the strength when serving iced - Delicious!
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Tulsi Immune Breathe Cooling Cardamom by Organic India label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Tulsi Immune Breathe Cooling Cardamom by Organic India
These are the 7 active ingredients this product is made of. Select any to open its full monograph.
Serving size8 fl. Oz. Dosage formOther (e.g. Tea Bag) Servings per container18 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Organic Blend
- › Licorice
- › Ginger
- › Cinnamon
- › Cardamom
- › Pushkarmool
- › Pippali
- › Organic Tulsi Blend
Tulsi Immune Breathe Cooling Cardamom by Organic India Drug Interactions
HelloPharmacist Interaction Report
Tulsi Immune Breathe Cooling Cardamom by Organic India interacts with medications through several of its ingredients.
The most serious concern is licorice's moderate interaction with digoxin (Lanoxin), a heart medication — licorice can increase the risk of heart toxicity when used together. Licorice also has moderate interactions with blood thinners like warfarin, heart rhythm drugs metabolized by your liver (CYP2B6, CYP2C19 substrates), cancer medications like cisplatin and paclitaxel, diuretics, and midazolam.
Read the full breakdown — every affected drug type, severity by severity
Ginger contributes moderate interactions with blood thinners and antiplatelet drugs (warfarin, phenprocoumon), diabetes medications, the blood pressure drug losartan, nifedipine, and cancer drugs that your liver processes (CYP3A4 substrates) or that depend on a cellular pump called P-glycoprotein. Cinnamon has moderate interactions with diabetes drugs and liver-toxic medications.
Pippali (Indian long pepper) interacts moderately with propranolol, diabetes drugs, theophylline, pentobarbital, cyclosporine, and again with CYP3A4 and P-glycoprotein substrates. Holy basil and East Indian basil both carry moderate interactions with blood thinners, diabetes drugs, and pentobarbital.
Pushkarmool (elecampane) has a moderate interaction with central nervous system depressants (sedatives and sleeping pills). Cardamom has no known interactions documented in our data.
Altogether, these interactions span 1,383 individual medications.
If you take any prescription medication—especially heart drugs, blood thinners, diabetes medicines, or sedatives—check your exact medications with the tool on this page before adding this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Tulsi Immune Breathe Cooling Cardamom?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Tulsi Immune Breathe Cooling Cardamom interact with 1,383 drugs. Click any drug to see the details.
6 of the 7 ingredients in Tulsi Immune Breathe Cooling Cardamom interact with drugs. Each result below shows which ingredient is responsible. Licorice Ginger Pippali Cinnamon Pushkarmool Organic Tulsi Blend
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Tulsi Immune Breathe Cooling Cardamom — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + 6-mercaptopurine interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Ado-trastuzumab Emtansine interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Ado-trastuzumab Emtansine interactionLicoriceCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Ado-trastuzumab Emtansine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Tulsi Immune Breathe Cooling Cardamom — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Tulsi Immune Breathe Cooling Cardamom — through 1 ingredient. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
Organic Tulsi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Organic Tulsi Blend + Abciximab interactionPippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Abciximab interactionGingerAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
LicoriceCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Abemaciclib interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Abemaciclib interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Abiraterone interactionLicoriceCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Abiraterone interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Abiraterone interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Abiraterone Acetate interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Abiraterone Acetate interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Abiraterone Acetate interactionLicoriceCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
GingerAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger + Abrocitinib interactionLicoriceCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
Read the full Licorice + Abrocitinib interactionOrganic Tulsi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Organic Tulsi Blend + Abrocitinib interactionPippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
PippaliP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase levels of P-glycoprotein substrates.
Read the full Pippali + Acalabrutinib interactionLicoriceP-glycoprotein Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
Read the full Licorice + Acalabrutinib interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates, P-glycoprotein Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acarbose interactionOrganic Tulsi BlendAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Tulsi Blend + Acarbose interactionPippaliAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Pippali + Acarbose interactionGingerAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Ginger + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Tulsi Immune Breathe Cooling Cardamom — through 2 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acebutolol interactionLicoriceAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, licorice might reduce the effects of antihypertensive drugs.
Read the full Licorice + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
PippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Acenocoumarol interactionGingerAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger + Acenocoumarol interactionOrganic Tulsi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Organic Tulsi Blend + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Tulsi Immune Breathe Cooling Cardamom — through 1 ingredient. Tap an ingredient for the detail:
PushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Tulsi Immune Breathe Cooling Cardamom — through 5 ingredients. Tap an ingredient for the detail:
GingerAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Ginger + Acetaminophen, Aspirin interactionPippaliAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
Read the full Pippali + Acetaminophen, Aspirin interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Aspirin interactionOrganic Tulsi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Organic Tulsi Blend + Acetaminophen, Aspirin interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Tulsi Immune Breathe Cooling Cardamom — through 5 ingredients. Tap an ingredient for the detail:
Organic Tulsi BlendAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Organic Tulsi Blend + Acetaminophen, Aspirin, Caffeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Aspirin, Caffeine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Aspirin, Caffeine interactionLicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Acetaminophen, Aspirin, Caffeine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Tulsi Immune Breathe Cooling Cardamom — through 3 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Butalbital interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Caffeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Caffeine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Butalbital, Caffeine interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Tulsi Immune Breathe Cooling Cardamom — through 5 ingredients. Tap an ingredient for the detail:
LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Acetaminophen, Butalbital, Caffeine, Codeine interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Caffeine, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Caffeine, Codeine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Butalbital, Caffeine, Codeine interactionPushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
PushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acetaminophen, Butalbital, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Codeine interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Butalbital, Codeine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
CinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Butalbital, Codeine Phosphate interactionPushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acetaminophen, Butalbital, Codeine Phosphate interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Butalbital, Codeine Phosphate interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Tulsi Immune Breathe Cooling Cardamom — through 5 ingredients. Tap an ingredient for the detail:
LicoriceCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Tulsi Immune Breathe Cooling Cardamom — through 5 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Codeine interactionPushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acetaminophen, Caffeine, Codeine interactionLicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Acetaminophen, Caffeine, Codeine interactionGingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Codeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Tulsi Immune Breathe Cooling Cardamom — through 5 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Codeine, Salicylamide interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Codeine, Salicylamide interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Tulsi Immune Breathe Cooling Cardamom — through 5 ingredients. Tap an ingredient for the detail:
LicoriceCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Caffeine, Dihydrocodeine interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Dihydrocodeine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Dihydrocodeine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Dihydrocodeine interactionPushkarmoolCns Depressants Moderate
Interaction Summary
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Read the full Pushkarmool + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
PippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Isometheptene interactionLicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Acetaminophen, Caffeine, Isometheptene interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Isometheptene interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
GingerCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Ginger might increase or decrease the levels of CYP3A4 substrates.
Read the full Ginger + Acetaminophen, Caffeine, Pyrilamine interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Caffeine, Pyrilamine interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Caffeine, Pyrilamine interactionLicoriceCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Licorice + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Tulsi Immune Breathe Cooling Cardamom — through 4 ingredients. Tap an ingredient for the detail:
LicoriceCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Read the full Licorice + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionGingerCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, ginger might increase the levels of CYP1A2 substrates.
Read the full Ginger + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionCinnamonHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
Read the full Cinnamon + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionPippaliCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
Read the full Pippali + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Tulsi Immune Breathe Cooling Cardamom with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Licorice
Antihypertensive Drugs
Theoretically, licorice might reduce the effects of antihypertensive drugs.
In human research, licorice increases blood pressure in a dose-dependent manner.
Cisplatin (Platinol-Aq)
Theoretically, licorice might reduce the effects of cisplatin.
In animal research, licorice diminished the therapeutic efficacy of cisplatin.
Corticosteroids
Theoretically, concomitant use of licorice and corticosteroids might increase the side effects of corticosteroids.
Case reports suggest that concomitant use of licorice and oral corticosteroids, such as hydrocortisone, can potentiate the duration of activity and increase blood levels of corticosteroids. Additionally, in one case report, a patient with neurogenic orthostatic hypertension stabilized on fludrocortisone 0.1 mg twice daily developed pseudohyperaldosteronism after recent consumption of large amounts of black licorice.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2B6.
In vitro research shows that licorice extract and glabridin, a licorice constituent, inhibit CYP2B6 isoenzymes. Licorice extract from the species G. uralensis seems to inhibit CYP2B6 isoenzymes to a greater degree than G. glabra extract in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2B6; however, these interactions have not yet been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C19.
In vitro, licorice extracts from the species G. glabra and G. uralensis inhibit CYP2C19 isoenzymes in vitro. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C19; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C8 (Cyp2C8) Substrates
Theoretically, licorice might increase levels of drugs metabolized by CYP2C8.
In vitro, licorice extract from the species G. glabra and G. uralensis inhibits CYP2C8 isoenzymes. Theoretically, these species of licorice might increase levels of drugs metabolized by CYP2C8; however, this interaction has not yet been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP2C9.
There is conflicting evidence about the effect of licorice on CYP2C9 enzyme activity. In vitro research shows that extracts from the licorice species G. glabra and G. uralensis moderately inhibit CYP2C9 isoenzymes. However, evidence from an animal model shows that licorice extract from the species G. uralensis can induce hepatic CYP2C9 activity. Until more is known, licorice should be used cautiously in people taking CYP2C9 substrates.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.
Pharmacokinetic research shows that the licorice constituent glycyrrhizin, taken in a dosage of 150 mg orally twice daily for 14 days, modestly decreases the area under the concentration-time curve of midazolam by about 20%. Midazolam is a substrate of CYP3A4, suggesting that glycyrrhizin modestly induces CYP3A4 activity. Animal research also shows that licorice extract from the species G. uralensis induces CYP3A4 activity. However, licorice extract from G. glabra species appear to inhibit CYP3A4-induced metabolism of testosterone in vitro. It is thought that the G. glabra inhibits CYP3A4 due to its constituent glabridin, which is a moderate CYP3A4 inhibitor in vitro and not present in other licorice species. Until more is known, licorice should be used cautiously in people taking CYP3A4 substrates.
Digoxin (Lanoxin)
Theoretically, concomitant use of licorice with digoxin might increase the risk of cardiac toxicity.
Overuse or misuse of licorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
Diuretic Drugs
Theoretically, concomitant use of licorice with diuretic drugs might increase the risk of hypokalemia.
Overuse of licorice might compound diuretic-induced potassium loss. In one case report, a 72-year-old male with a past medical history of hypertension, type 2 diabetes, hyperlipidemia, arrhythmia, stroke, and hepatic dysfunction was hospitalized with severe hypokalemia and uncontrolled hypertension due to pseudohyperaldosteronism. This was thought to be provoked by concomitant daily consumption of a product containing 225 mg of glycyrrhizin, a constituent of licorice, and hydrochlorothiazide 12.5 mg for 1 month.
Estrogens
Theoretically, licorice might increase or decrease the effects of estrogen therapy.
Theoretically, licorice might interfere with estrogen therapy due to estrogenic and anti-estrogenic effects.
Loop Diuretics
Theoretically, loop diuretics might increase the mineralocorticoid effects of licorice.
Theoretically, loop diuretics might enhance the mineralocorticoid effects of licorice by inhibiting the enzyme that converts cortisol to cortisone; however, bumetanide (Bumex) does not appear to have this effect.
Midazolam (Versed)
Theoretically, licorice might decrease levels of midazolam.
In humans, the licorice constituent glycyrrhizin appears to moderately induce the metabolism of midazolam. This is likely due to induction of cytochrome P450 3A4 by licorice. Until more is known, licorice should be used cautiously in people taking midazolam.
P-Glycoprotein Substrates
Theoretically, licorice might decrease the absorption of P-glycoprotein substrates.
In vitro research shows that licorice can increase P-glycoprotein activity.
Paclitaxel (Abraxane, Onxol)
Theoretically, licorice might decrease plasma levels and clinical effects of paclitaxel.
Multiple doses of licorice taken concomitantly with paclitaxel might reduce the effectiveness of paclitaxel. Animal research shows that licorice 3 grams/kg given orally for 14 days before intravenous administration of paclitaxel decreases the exposure to paclitaxel and increases its clearance. Theoretically, this occurs because licorice induces cytochrome P450 3A4 enzymes, which metabolize paclitaxel. Notably, a single dose of licorice did not affect exposure or clearance of paclitaxel.
Warfarin (Coumadin)
Theoretically, licorice might decrease plasma levels and clinical effects of warfarin.
Licorice seems to increase metabolism and decrease levels of warfarin in animal models. This is likely due to induction of cytochrome P450 2C9 (CYP2C9) metabolism by licorice. Advise patients taking warfarin to avoid taking licorice.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, licorice might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that licorice induces CYP1A2 enzymes.
Methotrexate (Trexall, Others)
Theoretically, licorice might increase levels of methotrexate.
Animal research suggests that intravenous administration of glycyrrhizin, a licorice constituent, and high-dose methotrexate may delay methotrexate excretion and increase systemic exposure, leading to transient elevations in liver enzymes and total bilirubin. This interaction has not yet been reported in humans.
Ginger
Anticoagulant/Antiplatelet Drugs
Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.
Antidiabetes Drugs
Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.
Losartan (Cozaar)
Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.
Nifedipine (Procardia)
Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.
P-Glycoprotein Substrates
Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Phenprocoumon (Marcoumar, Others)
Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.
Warfarin (Coumadin)
Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.
Calcium Channel Blockers
Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.
Cyclosporine (Neoral, Sandimmune)
Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2B6 (Cyp2B6) Substrates
Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.
Metronidazole (Flagyl)
Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.
Pippali
Anticoagulant/Antiplatelet Drugs
Theoretically, Indian long pepper might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that Indian long pepper extract inhibits platelet aggregation.
Antidiabetes Drugs
Theoretically, Indian long pepper might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that piperine, a constituent of Indian long pepper, can reduce blood glucose levels. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Cyclosporine (Neoral, Sandimmune)
Theoretically, Indian long pepper might increase the effects and adverse effects of cyclosporine.
In vitro research shows that piperine, a constituent of Indian long pepper, increases the bioavailability of cyclosporine.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, Indian long pepper might increase the effects and adverse effects of CYP3A4 substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, inhibits CYP3A4.
Nevirapine (Viramune)
Theoretically, Indian long pepper might increase blood levels of nevirapine.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases the plasma concentration and systemic exposure of nevirapine. However, no adverse effects were associated with the elevated plasma levels of nevirapine.
P-Glycoprotein Substrates
Theoretically, Indian long pepper might increase levels of P-glycoprotein substrates.
In vitro research shows that piperine, a constituent of Indian long pepper, can inhibit P-glycoprotein.
Pentobarbital (Nembutal)
Theoretically, Indian long pepper might increase the sedative effects of pentobarbital.
Animal research shows that piperine, a constituent of Indian long pepper, can increase pentobarbitone-induced sleeping time.
Phenytoin (Dilantin)
Theoretically, Indian long pepper might increase blood levels of phenytoin.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases phenytoin serum levels and slows its elimination.
Propranolol (Inderal)
Theoretically, Indian long pepper might increase blood levels of propranolol.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, accelerates absorption and increases serum concentrations of propranolol.
Rifampin (Rifadin)
Theoretically, Indian long pepper might increase blood levels of rifampin.
Piperine, a constituent of Indian long pepper, seems to increase absorption and serum levels of rifampin.
Theophylline
Indian long pepper might increase blood levels of theophylline.
A small pharmacokinetic study shows that piperine, a constituent of Indian long pepper, increases serum concentrations and slows elimination of theophylline.
Amoxicillin (Amoxil, Trimox)
Theoretically, Indian long pepper might increase the effects and adverse effects of amoxicillin.
Evidence from animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of amoxicillin when taken concomitantly.
Carbamazepine (Tegretol)
Theoretically, Indian long pepper might increase blood levels of carbamazepine.
A small pharmacokinetic study in patients taking carbamazepine 300 mg or 500 mg twice daily shows that a single 20 mg dose of purified piperine, which is a constituent of Indian long pepper, increases carbamazepine levels. Piperine may increase absorption by increasing blood flow to the GI tract, increasing the surface area of the small intestine, or by cytochrome P450 3A4 (CYP3A4) inhibition in the gut wall. Absorption was significantly increased by 7-10 mcg/mL/hour. The time to eliminate carbamazepine was also increased by 4-8 hours. Although carbamazepine levels were increased, this did not appear to increase side effects.
Cefotaxime (Claforan)
Theoretically, Indian long pepper might increase the effects and adverse effects of cefotaxime.
Animal research shows that piperine, a constituent of Indian long pepper, increases the plasma levels of cefotaxime when taken concomitantly.
Cinnamon
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Pushkarmool
Cns Depressants
Theoretically, elecampane may cause additive sedative effects when taken with CNS depressants.
Elecampane might have sedative effects.
Organic Tulsi Blend
Anticoagulant/Antiplatelet Drugs
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.
Antidiabetes Drugs
Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.
Pentobarbital (Nembutal)
Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.
Brand information
Manufacturer and brand details for Tulsi Immune Breathe Cooling Cardamom, from the product label.
Organic India
See all Organic India products- Name
- Organic India Pvt. Ltd.
- Street Address
- Factory: C-5/10, Agro Park Phase -II UPSIDC Industrial Area, Kursi Road
- City
- Barabanki
- State
- U.P.
- ZipCode
- 225302
Tulsi Immune Breathe Cooling Cardamom by Organic India: Common Questions
Does Tulsi Immune Breathe Cooling Cardamom by Organic India interact with any medications?
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Can I take this if I'm on a blood thinner like warfarin?
What's licorice in here for, and why is it a concern?
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Can I use this long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Tulsi Immune Breathe Cooling Cardamom’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Licorice
Interacts with 1,041 drugsLicorice root is a traditional remedy used for sore throats, coughs, and digestive complaints, but solid human evidence is limited for most uses. Regular licorice contains glycyrrhizin, whic...
Read the full Licorice monograph → Herb & supplement monographGinger
Interacts with 1,008 drugsGinger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...
Read the full Ginger monograph → Herb & supplement monographCassia Cinnamon
Interacts with 444 drugsCassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...
Read the full Cassia Cinnamon monograph → Herb & supplement monographCardamom
Cardamom is a popular cooking spice that has long been used in traditional medicine for digestion and fresh breath. As a food, it is generally safe for most people, but high-dose supplements...
Read the full Cardamom monograph → Herb & supplement monographElecampane
Interacts with 248 drugsElecampane is a traditional herb used mainly for coughs and other respiratory complaints, and as a bitter for digestion. Modern human evidence is very limited, so it should be seen as a folk...
Read the full Elecampane monograph → Herb & supplement monographIndian Long Pepper
Interacts with 897 drugsIndian long pepper (pippali) is a spice long used in Ayurvedic medicine and is best known for its piperine content, which may increase how well the body absorbs certain other substances. Mod...
Read the full Indian Long Pepper monograph → Herb & supplement monographHoly Basil
Interacts with 212 drugsHoly basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...
Read the full Holy Basil monograph →Sources & How We Checked
Tulsi Immune Breathe Cooling Cardamom's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 203 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Licorice 92 references
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- Brouwers, A. J. and van der, Meulen J. ['Licorice hypertension' also caused by licorice tea]. Ned.Tijdschr Geneeskd. 4-14-2001;145(15):744-747.
- van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Glycyrrhizin-induced reduction of ALT in European patients with chronic hepatitis C. Am J Gastroenterol 2001;96(8):2432-2437. PubMed
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- Shintani, S., Murase, H., Tsukagoshi, H., and Shiigai, T. Glycyrrhizin (licorice)-induced hypokalemic myopathy. Report of 2 cases and review of the literature. Eur Neurol 1992;32(1):44-51. PubMed
- Chen, M. F., Shimada, F., Kato, H., Yano, S., and Kanaoka, M. Effect of oral administration of glycyrrhizin on the pharmacokinetics of prednisolone. Endocrinol Jpn 1991;38(2):167-174. PubMed
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- Abe K, Higurashi T, Takahashi M, et al. Concomitant Use of High-dose Methotrexate and Glycyrrhizin Affects Pharmacokinetics of Methotrexate, Resulting in Hepatic Toxicity. In Vivo 2021;35(4):2163-2169. PubMed
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- Patel P, Aknouk M, Dawson A, et al. How Much Is Too Much? Exploring Pseudohyperaldosteronism in Glycyrrhizic Acid Toxicity From Chronic Licorice Root Consumption. Cureus 2021;13(7):e16454. PubMed
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- Gatica-Ortega ME, Pastor-Nieto MA. Allergic contact dermatitis to Glycyrrhiza inflata root extract in an anti-acne cosmetic product. Contact Dermatitis 2021;85(4):454-455.
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Ginger 64 references
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