Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Ultra Flora Restore Dairy Free Ingredients & Drug Interactions

by Metagenics

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Ultra Flora Restore Dairy Free is a dietary supplement by Metagenics with 3 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus NCFM. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Ultra Flora Restore Dairy Free by Metagenics

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.

Ultra Flora Restore Dairy Free contains 3 active probiotic ingredients: Lactobacillus acidophilus NCFM, Lactobacillus rhamnosus LGG, and Bifidobacterium animalis lactis (Bl-07). These are live beneficial bacteria designed to support gut health.

The product has no inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Lactobacillus Acidophilus's overall clinical evidence instead.

Moderate

Some clinical evidence supports Lactobacillus Acidophilus for:

Why this rating?
  • The label markets general wellness (“maintain digestive health and wellbeing”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Natural Medicines).

The data we hold covers only Lactobacillus acidophilus. It's rated possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

It's rated possibly ineffective for atopic disease (allergic conditions), and the evidence is too limited to rate it for acute respiratory distress syndrome. We don't have effectiveness data on file for the other two probiotic strains in this product.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Gastrointestinal side effects — epigastric discomfort, abdominal pain, bloating, flatulence, diarrhea, and burping — can occur when taking it with other probiotics, though these are uncommon.

Because L. acidophilus is a live organism, there's a theoretical concern it could cause infection in certain patients, though most documented cases involved bacteria moving from other parts of the body. Talk with your doctor before starting, especially if you have a compromised immune system.

For the other two probiotic strains, we don't have safety data on file.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before combining this product with antibiotic drugs. Antibiotics can kill the live bacteria in the probiotic and reduce its effectiveness — your healthcare provider can help you time them correctly.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with irritable bowel syndrome, antibiotic-related diarrhea, or bacterial vaginosis if the L. acidophilus component is effective for your situation. If you take antibiotics, timing matters — space them away from this supplement.

Anyone with a weakened immune system should check with their doctor first. Run your medications through the tool on this page, and talk it over with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ultra Flora Restore Dairy Free, straight from the product label.

Brand Metagenics
Barcode (UPC) 9315771010372
Net contents 30 Vegecap(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 305839
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ultra Flora Restore Dairy Free by Metagenics, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
9315771010372
IngredientAmount% DV
Lactobacillus acidophilus NCFM0 NP--
Lactobacillus rhamnosus LGG0 NP--
Bifidobacterium animalis lactis (Bl-07)0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Ultra Flora Restore Dairy Free is designed to be taken daily to support digestive health and maintain general wellbeing.

Vegetable capsules (VegeCaps) may be preferred by people wishing to avoid gelatin for health or religious reasons.

Maintain Digestive Health and Wellbeing

Ultra Flora Restore Dairy Free is designed to be taken daily to support digestive health and maintain general wellbeing.

Formula

Scientifically formulated, Ultra Flora Restore Dairy Free contains exclusive and extensively researched probiotics to enhance the growth of beneficial intestinal bacteria, support gut tissue restoration and to maintain healthy digestive system function.

Fridge Free Live Probiotic

Brand IP Statement(s)

NCFM is a registered trademark of DuPont. LGG is a registered trademark of Chr. Hansen A/S.

Precautions

Do not use if cap and/or bottle seals are missing or broken.

Practitioner only

If symptoms persist consult your healthcare professional.

FDA Statement of Identity

Dietary Supplement

General Statements

AUST L 329302

Suggested/Recommended/Usage/Directions

Directions for use: Adults and children over 5 years: Take 1 capsule daily, or as directed by your healthcare professional. Children under 5 years should use Ultra Flora Kids Care.

Storage

Store below 25 degrees C: Activ-Vial desiccant lined bottle protects probiotics to guarantee they stay live and effective without refrigeration.

See for yourself

Ultra Flora Restore Dairy Free by Metagenics label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Ultra Flora Restore Dairy Free by Metagenics

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lactobacillus acidophilus NCFM

Interacts with
182 drugs
0 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus NCFM monograph & interactions

Lactobacillus rhamnosus LGG

0 NP per serving

Bifidobacterium animalis lactis (Bl-07)

0 NP per serving
Interaction report

Ultra Flora Restore Dairy Free by Metagenics Drug Interactions

Want to check YOUR meds against Ultra Flora Restore Dairy Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Ultra Flora Restore Dairy Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus NCFM1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Ultra Flora Restore Dairy Free, from the product label.

Metagenics

See all Metagenics products
Name
Metagenics Australia
Street Address
741 Nudgee Road
City
Northgate
State
QLD
ZipCode
4013
Web Address
metagenics.com.au
Pharmacist Counseling Corner

Ultra Flora Restore Dairy Free by Metagenics: Common Questions

Does Ultra Flora Restore Dairy Free by Metagenics interact with any medications?
Yes. Based on its ingredients, Ultra Flora Restore Dairy Free has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ultra Flora Restore Dairy Free contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this with my antibiotics?
Not at the same time. Antibiotics can kill the live organisms in this probiotic and make it less effective. Ask your doctor or pharmacist how far apart to take them — usually a few hours or more is recommended.
What are these probiotic strains supposed to do?
Lactobacillus acidophilus may help with irritable bowel syndrome, antibiotic-related diarrhea, bacterial vaginosis, and H. pylori infection. We don't have effectiveness data on file for the other two strains in this product.
Will this give me digestive side effects?
Most people tolerate it well. Uncommon side effects when taken with other probiotics include bloating, gas, abdominal discomfort, and diarrhea. These usually pass quickly.
Is this safe to take if I'm pregnant?
Lactobacillus acidophilus is rated possibly safe in pregnancy, but we don't have safety data on file for the other two strains. Talk with your doctor or pharmacist to decide what's right for you.
Is this safe if I have a weak immune system?
You should check with your doctor first. Because this contains live bacteria, there's a theoretical concern for infection in people with compromised immunity, though it's uncommon.
Does 'dairy free' mean there's no milk in it?
Yes — this formulation doesn't contain milk or lactose, even though it has Lactobacillus (which just means 'milk-producing bacteria' by name, not ingredient).

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ultra Flora Restore Dairy Free is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ultra Flora Restore Dairy Free label
Sources

Sources & How We Checked

Ultra Flora Restore Dairy Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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