UltraFlora Acute Care Ingredients & Drug Interactions
by Metagenics
What is this page for?
First and foremost: checking UltraFlora Acute Care against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
UltraFlora Acute Care is a dietary supplement by Metagenics with 2 active ingredients. Its ingredients are commonly taken for acute diarrhea, antibiotic-associated diarrhea, traveler's diarrhea.Based on those ingredients, 222 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Probiotic Blend, Saccharomyces boulardii. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against UltraFlora Acute Care by Metagenics
Ask about any prescription or over-the-counter medication and we check it for interactions with UltraFlora Acute Care by Metagenics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of UltraFlora Acute Care by Metagenics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
UltraFlora Acute Care contains 3 active ingredients: Saccharomyces boulardii (a beneficial yeast), Bifidobacterium lactis HN019, and Lactobacillus rhamnosus HN001 — all live probiotic organisms meant to support digestive health. The product also contains inactive ingredients like capsule materials, silica, and magnesium stearate.
Does it work?
Moderate evidence
Saccharomyces boulardii in this product is rated possibly effective for several digestive conditions: rotaviral diarrhea, travelers' diarrhea, antibiotic-associated diarrhea, necrotizing enterocolitis (a serious intestinal condition in premature infants), Clostridioides difficile infection (a type of bacterial infection), and Helicobacter pylori (a stomach bacterium). We don't have effectiveness data on file for the other two probiotic strains in this product.
How safe is it?
Well-documented data
Saccharomyces boulardii is generally well tolerated in healthy adults but should be avoided by people who are critically ill or immunocompromised (those with weakened immune systems). Rarely, it has caused fungemia (yeast in the bloodstream), particularly in critically ill ICU patients with central lines, feeding tubes, or those on broad-spectrum antibiotics — most cases occurred when packets were opened or capsules broken.
Rarely, it may cause mild digestive complaints like cramps, gas, nausea, vomiting, or loss of appetite. Overall safety data is limited, so speak with your doctor before use.
We have no pregnancy or breastfeeding safety data on file for any ingredient in this product.
Meds to double-check
Minor interactions only
If you take antifungal medications, double-check before using this product — they may reduce how well the Saccharomyces boulardii in it works. We could not check the other probiotic strains for interactions, so mention those to your pharmacist too.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.
This product may help with certain types of diarrhea if you're generally healthy. If you're critically ill, immunocompromised, or taking antifungals, talk with your pharmacist or doctor first.
Check your medications against this product before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about UltraFlora Acute Care, straight from the product label.
| Brand | Metagenics |
|---|---|
| Barcode (UPC) | 755571918154 |
| Net contents | 30 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2023 |
| DSLD ID | 295877 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for UltraFlora Acute Care by Metagenics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Saccharomyces boulardii | 275 mg | -- |
| Probiotic Blend | 20 mg | -- |
| Bifidobacterium lactis HN019 | 0 NP | -- |
| Lactobacillus rhamnosus HN001 | 0 NP | -- |
Other ingredients: Active dried yeast, Hydroxypropyl Methylcellulose, Sodium Copper Chlorophyllin, B. lactis HN019, Stearic Acid, Silica, L. rhamnosus HN001, Magnesium Stearate, Microcrystalline Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
UltraFlora Acute Care is a unique blend of "friendly" bacteria and saccharomyces boulardii to support immune health and provide targeted relief for acute bowel distress including occasional loose stools. Ideal for traveling and backed by Metagenics ID guarantee.
Suggested/Recommended/Usage/Directions
Directions: Take one capsule one to two times daily or as directed by your healthcare practitioner.
Formulation
This product is non-GMO, gluten-free, and vegetarian.
This product is non-GMO, gluten-free, and vegetarian.
Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)
Targeted relief for acute bowel distress
Vegetarian capsule
Storage
Notice for maximum stability and viability, keep refrigerated. However, product may be stored at room temperature (65-75 degrees F) for up to one month without adversely affecting potency.
General Statements
This makes UltraFlora Acute Care and excellent choice for travelers.
At date of expiration
Seals/Symbols
Certified Gluten Free GFCO.org (Gluten-Free Certification Organization)
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Probiotic Supplement
Precautions
Practitioner exclusive
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
UltraFlora Acute Care by Metagenics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in UltraFlora Acute Care by Metagenics
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Saccharomyces boulardii
Interacts with40 drugs
Saccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea,...
Saccharomyces boulardii monograph & interactionsProbiotic Blend
Interacts with182 drugs
Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...
Probiotic Blend monograph & interactions- › Bifidobacterium lactis HN019
- › Lactobacillus rhamnosus HN001
Other (inactive) ingredients: Active dried yeast, Hydroxypropyl Methylcellulose, Sodium Copper Chlorophyllin, B. lactis HN019, Stearic Acid, Silica, L. rhamnosus HN001, Magnesium Stearate, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.
UltraFlora Acute Care by Metagenics Drug Interactions
HelloPharmacist Interaction Report
UltraFlora Acute Care by Metagenics contains live probiotic organisms, and we do have interaction data for one of them.
Saccharomyces boulardii, a beneficial yeast in this product, can interact with antifungals (Minor severity). Since S. boulardii is living yeast, antifungal medications may kill off a significant portion of the organisms, potentially reducing the product's effectiveness.
Read the full breakdown — every affected drug type, severity by severity
We could not check two other probiotic strains in this product — Bifidobacterium lactis HN019 and Lactobacillus rhamnosus HN001 — because we hold no interaction data for them. Altogether, these interactions span 40 individual medications.
If you take an antifungal or any other prescription medication, run it through the checker below before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against UltraFlora Acute Care?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in UltraFlora Acute Care interact with 222 drugs. Click any drug to see the details.
2 of the 2 ingredients in UltraFlora Acute Care interact with drugs. Each result below shows which ingredient is responsible. Probiotic Blend Saccharomyces boulardii
AmikacinAmikin, Arikayce
How Amikacin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCapreomycinCapastat
How Capreomycin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Capreomycin interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefixime interactionCefmetazoleZefazone
How Cefmetazole interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefmetazole interactionCefonicidMonocid
How Cefonicid interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefonicid interactionCefoperazoneCefobid
How Cefoperazone interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefoperazone interactionCefotaximeClaforan
How Cefotaxime interacts with UltraFlora Acute Care — through 1 ingredient. Tap an ingredient for the detail:
Probiotic BlendAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L.
Read the full Probiotic Blend + Cefotaxime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in UltraFlora Acute Care with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Probiotic Blend
Antibiotic Drugs
Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.
Saccharomyces boulardii
Antifungals
Theoretically, taking antifungals with Saccharomyces boulardii might decrease the effectiveness of Saccharomyces boulardii.
S. boulardii is a live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.
Brand information
Manufacturer and brand details for UltraFlora Acute Care, from the product label.
Metagenics
See all Metagenics products- Name
- Metagenics
- City
- Gig Harbor
- State
- WA
- ZipCode
- 98332
- Phone Number
- 800 692 9400
UltraFlora Acute Care by Metagenics: Common Questions
Does UltraFlora Acute Care by Metagenics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe if I'm on antibiotics?
What is Saccharomyces boulardii?
Can I take this if I'm immunocompromised?
Will this help my traveler's diarrhea?
Can I take this while pregnant or breastfeeding?
What if I open the capsule?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if UltraFlora Acute Care is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind UltraFlora Acute Care’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Saccharomyces Boulardii
Interacts with 40 drugsSaccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea, including antibiotic-associated diarrhea...
Read the full Saccharomyces Boulardii monograph → Herb & supplement monographLactobacillus Acidophilus
Interacts with 182 drugsLactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...
Read the full Lactobacillus Acidophilus monograph →Sources & How We Checked
UltraFlora Acute Care's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Saccharomyces Boulardii 26 references
- Niault M, Thomas F, Prost J, et al. Fungemia due to Saccharomyces species in a patient treated with enteral Saccharomyces boulardii. Clin Infect Dis 1999;28:930.
- Pletinex M, Legein J, Vandenplas Y. Fungemia with Saccharomyces boulardii in a 1-year-old girl with protracted diarrhea. J Pediatr Gastroenterol Nutr 1995;21:113-5. DOI
- Fredenucci I, Chomarat M, Boucaud C, et al. Saccharomyces boulardii fungemia in a patient receiving ultra-levure therapy. Clin Infect Dis 1998;27:222-3.
- Elmer GW, McFarland LV, Surawicz CM, et al. Behaviour of Saccharomyces boulardii in recurrent Clostridium difficile disease patients. Aliment Pharmacol Ther 1999;13:1663-8.
- Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
- Cesaro S, Chinello P, Rossi L, Zanesco L. Saccharomyces cerevisiae fungemia in a neutropenic patient treated with Saccharomyces boulardii. Support Care Cancer 2000;8:504-5. PubMed
- Hennequin C, Thierry A, Richard GF, et al. Microsatellite typing as a new tool for identification of Saccharomyces cerevisiae strains. J Clin Microbiol 2001;39:551-9.
- Plein K, Hotz J. Therapeutic effects of Saccharomyces boulardii on mild residual symptoms in a stable phase of Crohn's disease with special respect to chronic diarrhea - a pilot study. Z Gastroenterol 1993;31:129-34.
- Borriello SP, Hammes WP, Holzapfel W, et al. Safety of probiotics that contain lactobacilli or bifidobacteria. Clin Infect Dis 2003;36:775-80. PubMed
- Marteau P, Seksik P. Tolerance of probiotics and prebiotics. J Clin Gastroenterol 2004;38:S67-9. PubMed
- Munoz P, Bouza E, Cuenca-Estrella M, et al. Saccharomyces cerevisiae fungemia: an emerging infectious disease. Clin Infect Dis 2005;40:1625-34. PubMed
- Lherm, T., Monet, C., Nougiere, B., Soulier, M., Larbi, D., Le Gall, C., Caen, D., and Malbrunot, C. Seven cases of fungemia with Saccharomyces boulardii in critically ill patients. Intensive Care Med 2002;28(6):797-801. PubMed
- Riquelme, A. J., Calvo, M. A., Guzman, A. M., Depix, M. S., Garcia, P., Perez, C., Arrese, M., and Labarca, J. A. Saccharomyces cerevisiae fungemia after Saccharomyces boulardii treatment in immunocompromised patients. J Clin.Gastroenterol. 2003;36(1):41- PubMed
- Cherifi, S., Robberecht, J., and Miendje, Y. Saccharomyces cerevisiae fungemia in an elderly patient with Clostridium difficile colitis. Acta Clin Belg. 2004;59(4):223-224. PubMed
- Ellouze O, Berthoud V, Mervant M, Parthiot JP, Girard C. Septic shock due to Sacccaromyces boulardii. Med Mal Infect. 2016;46(2):104-105.
- Appel-da-Silva MC, Narvaez GA, Perez LRR, Drehmer L, Lewgoy J. Saccharomyces cerevisiae var. boulardii fungemia following probiotic treatment. Med Mycol Case Rep. 2017;18:15-7. PubMed
- Atici S, Soysal A, Karadeniz Cerit K, et al. Catheter-related Saccharomyces cerevisiae Fungemia Following Saccharomyces boulardii Probiotic Treatment: In a child in intensive care unit and review of the literature. Med Mycol Case Rep. 2017;15:33-35. PubMed
- Martin IW, Tonner R, Trivedi J, et al. Saccharomyces boulardii probiotic-associated fungemia: questioning the safety of this preventive probiotic's use. Diagn Microbiol Infect Dis. 2017;87(3):286-8. PubMed
- Romanio MR, Coraine LA, Maielo VP, Abramczyc ML, Souza RL, Oliveira NF. Saccharomyces cerevisiae fungemia in a pediatric patient after treatment with probiotics. Rev Paul Pediatr 2017;35(3):361-4.
- Roy U, Jessani LG, Rudramurthy SM, et al. Seven cases of Saccharomyces fungaemia related to use of probiotics. Mycoses 2017;60(6):375-380.
- Romanio MR, Coraine LA, Maielo VP, Abramczyc ML, Souza RL, Oliveira NF. Saccharomyces cerevisiae fungemia in a pediatric patient after treatment with probiotics. Rev Paul Pediatr. 2017 Jul-Sep;35(3):361-364. doi: 10.1590/1984-0462/;2017;35;3;00014.
- Flatley EA, Wilde AM, Nailor MD. Saccharomyces boulardii for the prevention of hospital onset Clostridium difficile infection. J Gastrointestin Liver Dis. 2015;24(1):21-4. PubMed
- Ventoulis I, Sarmourli T, Amoiridou P, et al. Bloodstream infection by Saccharomyces cerevisiae in two COVID-19 patients after receiving supplementation of Saccharomyces in the ICU. J Fungi (Basel). 2020;6(3):98. PubMed
- Wombwell E, Bransteitter B, Gillen LR. Incidence of Saccharomyces cerevisiae fungemia in hospitalised patients administered Saccharomyces boulardii probiotic. Mycoses 2021;64(12):1521-1526.
- Rannikko J, Holmberg V, Karppelin M, et al. Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements. Emerg Infect Dis 2021;27(8):2090-6.
- Awoyemi A, Mayerhofer C, Felix AS, et al. Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial. EBioMedicine 2021;70:103511. PubMed
See these in context on the Saccharomyces Boulardii monograph →
Lactobacillus Acidophilus 15 references
- Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
- Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
- Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
- Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
- Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
- Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
- Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
- Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
- Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
- Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
- Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
- Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
- Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.
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