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Dietary supplement

Vanadyl Sulfate 10 mg Ingredients & Drug Interactions

by Source Naturals

Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Vanadyl Sulfate 10 mg is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for blood sugar and diabetes support, athletic performance and muscle building, lowering cholesterol.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vanadyl Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vanadyl Sulfate 10 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Vanadyl Sulfate” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

This supplement contains one active ingredient: vanadium (supplied as vanadyl sulfate), providing 10 mg per tablet. Vanadium is a trace mineral that your body uses in small amounts.

The tablet also contains microcrystalline cellulose, stearic acid, and silica as inactive ingredients—standard binders and flow agents that help hold the tablet together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Vanadium's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports glucose transport and metabolism.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), blood sugar control, glycemic management.
  • The closest evidence on file: Vanadium is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Vanadium is rated "Insufficient Reliable Evidence To Rate" for Impaired glucose tolerance (prediabetes).

The evidence for vanadium is mixed. It's considered likely effective for vanadium deficiency, which is rare.

For everything else this product might be marketed for—athletic performance, cancer, diabetes, and high cholesterol—the evidence isn't established enough in our data to say whether it works. A few small studies hint it might help with blood sugar control in type 2 diabetes, but that's not solid proof.

The evidence, ingredient by ingredient Vanadium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vanadium at typical dietary levels is generally well tolerated. This supplement provides 10 mg, which is well above the safe upper limit of 1.8 mg daily, so side effects are possible.

At higher doses, people report stomach upset—nausea, diarrhea, abdominal discomfort, and gas. Long-term use at high doses has rarely caused kidney damage.

Allergic reactions to vanadium are uncommon but documented; they show up as itchy rashes and eye irritation. The safety data advises against vanadium supplements during pregnancy and breastfeeding, so talk with your doctor or pharmacist if you're pregnant or nursing.

Side effects, ingredient by ingredient Vanadium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vanadium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check if you're on any blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel—vanadium may increase bleeding risk. Also double-check if you take diabetes medications; vanadium might lower your blood sugar too much.

Both interactions are Moderate severity.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Vanadium supplements aren't established as effective for most conditions we have data on. If you take blood thinners, diabetes medications, or antiplatelet drugs, you'll want to check with your pharmacist before starting this—the interaction risk is real.

For everyone else, the main watch is side effects at this dose and long-term safety, which isn't fully known.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vanadyl Sulfate 10 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078017479
Net contents 100 Tablet(s)
Market status On market
Date entered into DSLD Jan 23, 2023
DSLD ID 273342
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vanadyl Sulfate 10 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
100
UPC/BARCODE
021078017479
IngredientAmount% DV
Vanadium2 mg--
Vanadyl Sulfate10 mg--

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

Formulation

Supports glucose transport

Suitable for Vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat.

Suitable for Vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat.

Suitable for Vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

Formula

Athletes have used vanadyl sulfate extensively as part of their daily supplementation program. It is a form of the trace element vanadium, which is important for normal growth and development. Vanadyl sulfate may help support glucose metabolism by its insulin-like effects in the liver, skeletal muscle, and adipose tissue, by activating glucose transport at the cellular level. Preliminary research suggests that Source Naturals Vanadyl Sulfate may help maintain healthy blood sugar levels when used as part of a healthy diet.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 tablet daily with food. Do not exceed suggested use.

Precautions

Do not exceed suggested use.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Caution: If you are pregnant, may become pregnant, or breastfeeding, have any disorder of blood sugar metabolism, or if you are taking insulin or any other medication for glucose control, or any lipid-lowering, anticoagulant or antiplatelet medication, please consult your physician before using this product.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Copyright SOURCE NATURALS, INC.

See for yourself

Vanadyl Sulfate 10 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vanadyl Sulfate 10 mg by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container100 Amounts shown are per serving.

Vanadyl Sulfate

Interacts with
208 drugs
10 mg per serving

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...

Vanadyl Sulfate monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vanadyl Sulfate 10 mg by Source Naturals Drug Interactions

Want to check YOUR meds against Vanadyl Sulfate 10 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Vanadyl Sulfate 10 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vanadyl Sulfate2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Vanadyl Sulfate 10 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Vanadyl Sulfate 10 mg by Source Naturals: Common Questions

Does Vanadyl Sulfate 10 mg by Source Naturals interact with any medications?
Yes. Based on its ingredients, Vanadyl Sulfate 10 mg has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vanadyl Sulfate 10 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this dose safe?
This 10 mg dose is above the safe upper limit of 1.8 mg daily, so it carries a real risk of side effects. The data shows it's generally well tolerated at lower amounts, but higher doses can cause stomach upset and other effects. Talk with your pharmacist about whether this dose is right for you.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against vanadium supplements during pregnancy and while breastfeeding. If you're in either situation, talk with your doctor or pharmacist before taking this.
What is vanadium actually for?
Your body needs trace amounts of vanadium. The main established use for a supplement is treating vanadium deficiency, which is uncommon. For diabetes, high cholesterol, and athletic performance, the evidence isn't strong enough yet to say it works.
What side effects might I get?
At this higher dose, the most common side effects are gastrointestinal—nausea, diarrhea, belly discomfort, and gas. Rare allergic reactions (itchy rashes, eye irritation) have been reported. Long-term use at high doses has rarely caused kidney damage.
How is vanadyl sulfate different from regular vanadium?
Vanadyl sulfate is just one form of vanadium that's used in supplements because it's easier to absorb. The ingredient list shows both names because they refer to the same active mineral.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vanadyl Sulfate 10 mg label
Go deeper

The Full Monographs Behind Vanadyl Sulfate 10 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Vanadyl Sulfate 10 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vanadium 15 references
  1. Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
  2. Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
  3. Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
  4. Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
  5. Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9. PubMed
  6. Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
  9. Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
  10. Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092. PubMed
  11. Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110. PubMed
  12. Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8. PubMed
  13. Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9. PubMed
  14. Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028. PubMed
  15. Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787. PubMed

See these in context on the Vanadium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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