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Dietary supplement

Vanadyl Sulfate 10 mg Ingredients & Drug Interactions

by Source Naturals

Vanadyl Sulfate 10 mg label
See full label image
Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Vanadyl Sulfate 10 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Vanadyl Sulfate 10 mg is a dietary supplement by Source Naturals with 1 active ingredient. Its ingredients are commonly taken for blood sugar and diabetes support, athletic performance and muscle building, lowering cholesterol.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vanadyl Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Vanadyl Sulfate 10 mg by Source Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Vanadyl Sulfate 10 mg by Source Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Vanadyl Sulfate 10 mg by Source Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Vanadyl Sulfate” is listed as a grouped ingredient — the label gives one combined amount (10 mg) without saying how much of each component you get.

This product contains one active ingredient: vanadium (in the form of vanadyl sulfate, 10 mg per tablet). Vanadium is a trace mineral that your body needs in very small amounts.

The tablet also contains inactive ingredients—microcrystalline cellulose (a binder), stearic acid, and silica—to hold the pill together and aid absorption.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Vanadium's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports glucose transport and metabolism.
  • We looked for evidence on: Diabetes, Impaired glucose tolerance (prediabetes), Blood sugar control, Glucose homeostasis.
  • The closest evidence on file: Vanadium is rated "Insufficient Reliable Evidence To Rate" for Diabetes (Natural Medicines).
  • Also on file: Vanadium is rated "Insufficient Reliable Evidence To Rate" for Impaired glucose tolerance (prediabetes).

The evidence shows that vanadium is likely effective for treating vanadium deficiency, which is the body's lack of this essential trace mineral. For other uses—including athletic performance, cancer, diabetes, and high cholesterol—the current evidence is insufficient to rate whether it works.

That doesn't mean it doesn't work; it means we don't yet have reliable studies to say either way.

The evidence, ingredient by ingredient Vanadium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vanadium is generally well tolerated when you stay below the tolerable upper intake level of 1.8 mg daily. At higher doses—like the 10 mg in this supplement—side effects become more likely.

The most common are gastrointestinal problems: abdominal discomfort, diarrhea, gas, and nausea. Rarely, long-term use at high doses has been linked to kidney damage.

Allergic reactions to vanadium are uncommon but possible; a few cases of rash and contact dermatitis have been reported in people exposed to vanadium metal.

Side effects, ingredient by ingredient Vanadium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vanadium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you're on blood thinners or antiplatelet drugs (Moderate interaction risk), or antidiabetes medications (Moderate interaction risk). Either could be affected by vanadium's effects on clotting and blood sugar.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This supplement makes sense if you have a confirmed vanadium deficiency, though that's rare. If you take blood thinners, diabetes medications, or antiplatelet drugs, check with your pharmacist before starting—the interactions could affect how well your medications work or increase your risk of bleeding or low blood sugar.

Because of the gastrointestinal side effects at higher doses, it's worth discussing with your doctor whether this dose is right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vanadyl Sulfate 10 mg, straight from the product label.

Brand Source Naturals
Barcode (UPC) 021078026952
Net contents 200 Tablet(s)
Market status On market
Date entered into DSLD Jan 25, 2018
DSLD ID 78809
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vanadyl Sulfate 10 mg by Source Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
UPC/BARCODE
021078026952
IngredientAmount% DV
Vanadium2 mg--
Vanadyl Sulfate10 mg--

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Dietary Supplement

General Statements

Supports glucose transport

Athletes have used vanadyl sulfate extensively as part of their daily supplementation program. It is a form of the trace element vanadium, which is important for normal growth and development. Vanadyl sulfate may help support glucose metabolism by its insulinlike effects in the liver, skeletal muscle, and adipose tissue, by activating glucose transport at the cellular level. Preliminary research suggests that Source Naturals Vanadyl Sulfate may help maintain healthy blood sugar levels when used as part of a healthy diet.

Suggested/Recommended/Usage/Directions

Suggested Use: 1 tablet daily with food. Do not exceed suggested use.

Precautions

Do not exceed suggested use.

Do not use if either tamper-evident seal is broken or missing.

Keep out of the reach of children.

Caution: If you are pregnant, may become pregnant, or breastfeeding, have any disorder of blood sugar metabolism, or if you are taking insulin or any other medication for glucose control, or any lipidlowering, anticoagulant or antiplatelet medication, please consult your physician before using this product.

Storage

Store in a cool, dry place.

Formulation

Suitable for Vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat.

Suitable for Vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat.

Suitable for Vegetarians and Hypoallergenic: Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt, preservatives, or artificial color, flavor or fragrance.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

SN2695 REV H153

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Vanadyl Sulfate 10 mg by Source Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Vanadyl Sulfate 10 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Vanadyl Sulfate 10 mg by Source Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.

Vanadyl Sulfate

Interacts with
208 drugs
10 mg per serving

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...

Vanadyl Sulfate monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vanadyl Sulfate 10 mg by Source Naturals Drug Interactions

Want to check YOUR meds against Vanadyl Sulfate 10 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Vanadyl Sulfate 208

Individual Drug Interactions

The ingredients in Vanadyl Sulfate 10 mg interact with 208 drugs. Click any drug to see the details.

1 of the 1 ingredient in Vanadyl Sulfate 10 mg interact with drugs. Each result below shows which ingredient is responsible. Vanadyl Sulfate

Each ingredient & the kinds of drugs it affects

For each ingredient in Vanadyl Sulfate 10 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vanadyl Sulfate2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
Vanadyl Sulfate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Vanadyl Sulfate 10 mg, from the product label.

Source Naturals

Name
Source Naturals, Inc.
Street Address
P. O. Box 2118
City
Santa Cruz
State
CA
ZipCode
95062
Web Address
www.sourcenaturals.com
Pharmacist Counseling Corner

Vanadyl Sulfate 10 mg by Source Naturals: Common Questions

Does Vanadyl Sulfate 10 mg by Source Naturals interact with any medications?
Yes. Based on its ingredients, Vanadyl Sulfate 10 mg has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vanadyl Sulfate 10 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
Not without checking first. Vanadium may increase your bleeding risk when combined with blood thinners—lab studies show it can prolong clotting time. Talk to your pharmacist or doctor before you add this supplement.
What if I take medication for diabetes?
You'll need to check with your doctor or pharmacist. Vanadium may lower blood sugar on its own, so taking it alongside diabetes drugs could cause your blood sugar to drop too low. They can help you decide if it's safe or if your diabetes medication needs adjusting.
Is vanadium naturally in food, or do I need a supplement?
Vanadium is found in small amounts in food—grains, legumes, shellfish, and other sources. The amounts in food are fine. Supplements like this one contain much higher doses, which is why the safety concerns apply.
What are the most common side effects if I take this?
At doses above the recommended upper limit of 1.8 mg daily, most people who experience problems report gastrointestinal issues: nausea, diarrhea, abdominal discomfort, and gas. This product is 10 mg, well above that limit, so GI upset is a real possibility.
Can I take this while pregnant or breastfeeding?
No. There isn't enough safety information for vanadium supplements during pregnancy, so you should avoid it. The same goes for breastfeeding—safety data doesn't exist, so it's best to skip it. Talk to your doctor if you're considering it.
Does this actually work for diabetes?
The evidence isn't established yet. A few very small studies in people with type 2 diabetes suggest vanadium might improve insulin sensitivity and lower blood sugar, but we don't have enough reliable research to say it works. It's listed as insufficient evidence to rate.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vanadyl Sulfate 10 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vanadyl Sulfate 10 mg label
Go deeper

The Full Monographs Behind Vanadyl Sulfate 10 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vanadium

Interacts with 208 drugs

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athletic performance are not well proven, and...

Read the full Vanadium monograph →
Sources

Sources & How We Checked

Vanadyl Sulfate 10 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vanadium 15 references
  1. Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
  2. Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
  3. Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
  4. Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
  5. Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9. PubMed
  6. Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
  9. Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
  10. Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092. PubMed
  11. Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110. PubMed
  12. Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8. PubMed
  13. Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9. PubMed
  14. Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028. PubMed
  15. Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787. PubMed

See these in context on the Vanadium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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