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Dietary supplement

Vanadyl Sulfate 5000 mcg Ingredients & Drug Interactions

by Country Life

Capsule Category: Other Combinations
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Vanadyl Sulfate 5000 mcg is a dietary supplement by Country Life with 1 active ingredient. Its ingredients are commonly taken for blood sugar and diabetes support, athletic performance and muscle building, lowering cholesterol.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vanadium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vanadyl Sulfate 5000 mcg by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Vanadium” is listed as a grouped ingredient — the label gives one combined amount (975 mcg) without saying how much of each component you get.

This product contains one active ingredient: vanadyl sulfate, a form of vanadium. The capsule also holds three inactive ingredients—cellulose, magnesium stearate, and silica—which are fillers and binders that help hold the capsule together.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: blood sugar and athletic performance support.
  • We looked for evidence on: Athletic performance, Diabetes, Impaired glucose tolerance (prediabetes), Insulin sensitivity, Metabolic health.
  • The closest evidence on file: Vanadium is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Vanadium is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Impaired glucose tolerance (prediabetes).

The facts support vanadium for vanadium deficiency only, where it is likely effective. For athletic performance, diabetes, high cholesterol, and cancer, the evidence is insufficient to rate it—we simply don't have enough reliable data to say whether it works for those purposes.

The evidence, ingredient by ingredient Vanadium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vanadium is generally well tolerated at small dietary amounts. However, this supplement dose can cause side effects, and the tolerable upper intake level is 1.8 mg daily.

Above that, you may experience stomach upset—abdominal discomfort, diarrhea, gas, and nausea. Rarely, long-term use at high doses has been linked to kidney damage.

Allergic reactions to vanadium metal have been reported, including rashes and contact dermatitis. The safety data advises against taking vanadium supplements during pregnancy.

While breastfeeding, the safety is unknown; there isn't enough information to know whether it's safe, so talk with your pharmacist or doctor before use if you're nursing.

Side effects, ingredient by ingredient Vanadium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vanadium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your pharmacist if you take blood thinners or antiplatelet drugs (warfarin, clopidogrel, aspirin), which carry a Moderate risk of increased bleeding. Also check any diabetes medications you're on, as vanadium may lower blood sugar.

Use the search tool on this page to run your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is appropriate only if you have vanadium deficiency confirmed by your doctor. If you take blood thinners or diabetes medications, you must check with your pharmacist first—the interaction risk is real.

Pregnant women and those breastfeeding should avoid it. Talk to your pharmacist about whether this supplement fits your health needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vanadyl Sulfate 5000 mcg, straight from the product label.

Brand Country Life
Barcode (UPC) 015794016984
Net contents 90 Vegan Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2015
DSLD ID 41784
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vanadyl Sulfate 5000 mcg by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
015794016984
IngredientAmount% DV
Vanadium975 mcg--
Vanadyl Sulfate5000 mcg--

Other ingredients: Cellulose, Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

** These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

YES CERTIFIED GLUTEN-FREE BY GFCO.ORG

YES CERTIFIED VEGAN BY THE AVA

NO YEAST, WHEAT OR CORN NO SOY OR MILK NO SALT OR SUGAR NO PRESERVATIVES NO ARTIFICIAL COLOR

Certified Gluten-Free

General Statements

YES RECYCLABLE PACKAGING YES MANUFACTURING SUPPORTS WIND POWER

ESTABLISHED IN 1971

Vanadium is a trace mineral from vanadyl sulfate. Available in 90 and 180 vegan capsules.

This product has been manufactured at a GMP Registered facility.

That are already within a healthy normal range.*

- Super potency - Supports muscle fullness** - May help support healthy blood sugar levels**

Our PLEDGE of INTEGRITY AUTHENTICITY - CLEANLINESS - FRESHNESS CONSISTENCY - ACCURACY

As a reminder, discuss the supplements and medications that you take with your health care providers.

Precautions

If any adverse reactions occur, stop taking the product and consult your doctor.

Do not accept if seal is broken.

Keep out of the reach of children.

CAUTION: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

Storage

Store between 59(0)-86(0) F.

General

Product No. 1698 11L14NL

Formula

YES KOSHER

Seals/Symbols

K

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) capsule daily with food or as directed by a health care professional.

See for yourself

Vanadyl Sulfate 5000 mcg by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vanadyl Sulfate 5000 mcg by Country Life

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Vanadium

Interacts with
208 drugs
975 mcg per serving

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...

Vanadium monograph & interactions

Other (inactive) ingredients: Cellulose, Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vanadyl Sulfate 5000 mcg by Country Life Drug Interactions

Want to check YOUR meds against Vanadyl Sulfate 5000 mcg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Vanadium 208

Each ingredient & the kinds of drugs it affects

For each ingredient in Vanadyl Sulfate 5000 mcg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vanadium2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Vanadyl Sulfate 5000 mcg, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Vanadyl Sulfate 5000 mcg by Country Life: Common Questions

Does Vanadyl Sulfate 5000 mcg by Country Life interact with any medications?
Yes. Based on its ingredients, Vanadyl Sulfate 5000 mcg has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vanadyl Sulfate 5000 mcg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is vanadyl sulfate, and what is it supposed to do?
Vanadyl sulfate is a form of the mineral vanadium. The only use supported by evidence is treating vanadium deficiency. The supplement is sometimes marketed for athletic performance, diabetes, and high cholesterol, but we don't have enough reliable data to say it works for those.
How much vanadium is safe to take daily?
The tolerable upper intake level is 1.8 mg daily. This product contains 5000 mcg—that's 5 mg, which is above that limit. Doses above the upper limit may cause stomach upset and, with long-term high-dose use, kidney damage.
What side effects should I watch for?
The most common are stomach issues: abdominal discomfort, diarrhea, gas, and nausea—especially if you exceed the safe daily amount. Allergic reactions (rashes, itching) are possible in people sensitive to vanadium. Rarely, long-term high-dose use can damage the kidneys.
Is it safe to take this while I'm pregnant or breastfeeding?
No, the safety data advises against vanadium supplements during pregnancy. While breastfeeding, there isn't enough safety information to know either way—talk with your pharmacist or doctor for personalized advice.
Will this affect my blood pressure or cholesterol?
The evidence for vanadium and high cholesterol is insufficient—we don't have reliable data to say it works. Nothing in the data provided tells us about a blood pressure effect.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vanadyl Sulfate 5000 mcg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vanadyl Sulfate 5000 mcg label
Go deeper

The Full Monographs Behind Vanadyl Sulfate 5000 mcg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Vanadyl Sulfate 5000 mcg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vanadium 15 references
  1. Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
  2. Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
  3. Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
  4. Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
  5. Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9. PubMed
  6. Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
  9. Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
  10. Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092. PubMed
  11. Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110. PubMed
  12. Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8. PubMed
  13. Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9. PubMed
  14. Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028. PubMed
  15. Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787. PubMed

See these in context on the Vanadium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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