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Dietary supplement

Vanadyl Sulfate Ingredients & Drug Interactions

by Country Life

Capsule Category: Mineral
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Vanadyl Sulfate is a dietary supplement by Country Life with 1 active ingredient. Its ingredients are commonly taken for blood sugar and diabetes support, athletic performance and muscle building, lowering cholesterol.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vanadium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Vanadyl Sulfate by Country Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: vanadium, in the form of vanadyl sulfate. The capsule also holds inactive ingredients—cellulose, magnesium stearate, and silica—which are fillers and binders that help hold the supplement together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Vanadium's overall clinical evidence instead.

Strong

Strong clinical evidence supports Vanadium for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Vanadium deficiency — rated "Likely Effective" (Natural Medicines).

The evidence we hold shows vanadium is likely effective for vanadium deficiency—a lack of this mineral in your body. For other uses—athletic performance, cancer, type 2 diabetes, and high cholesterol—the research isn't established enough for us to rate it.

The small clinical studies on diabetes did suggest vanadium might lower blood glucose, but that's not the same as proven effectiveness for treating diabetes.

The evidence, ingredient by ingredient Vanadium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vanadium is well tolerated when you stay below 1.8 mg daily. Higher doses may cause stomach upset—nausea, diarrhea, gas, and belly discomfort.

Over the long term at high doses, there's a rare risk of kidney damage. Allergic reactions to vanadium are uncommon but have been reported, showing up as rash, itching, or contact dermatitis in sensitive people.

The safety data advises against taking vanadium supplements during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Vanadium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Vanadium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, check if you use blood thinners or antiplatelet drugs (Moderate risk of increased bleeding) or diabetes medications (Moderate risk of low blood sugar). These are the two drug types with documented interactions in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Vanadyl Sulfate is mainly useful if you have a vanadium deficiency. If you take blood thinners, antiplatelet drugs, or diabetes medications, talk to your pharmacist before starting this supplement—the interactions could be important.

Stick to low doses and watch for stomach upset.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Vanadyl Sulfate, straight from the product label.

Brand Country Life
Barcode (UPC) 015794016991
Net contents 180 Vegan Capsule(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 333321
Product type Mineral
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Vanadyl Sulfate by Country Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
180
UPC/BARCODE
015794016991
IngredientAmount% DV
Vanadium975 mcg--

Other ingredients: Cellulose, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Vanadium is a trace mineral from vanadyl sulfate.

Yes Kosher

Vanadyl Sulfate providing vanadium

General Statements

Available in 90 and 180 vegan capsules.

Yes recyclable packaging

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formulation

Yes certified gluten-free by GFCO.org No yeast, wheat or corn No soy, milk or salt No sugar or preservatives No artificial colors, flavors or sweeteners

Yes certified vegan by the AVA

Yes manufacturing supports wind power

This product has been manufactured at a GMP Registered facility.

Certified gluten-free

Super potency May help support health blood sugar levels That are already within a healthy normal range.

Our Pledge of Integrity Authenticity Cleanliness Freshness Consistency Accuracy

Seals/Symbols

Certified B Corporation GF Certified Gluten-free K (Kosher)

Brand IP Statement(s)

Country Life Established 1971

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults take one (1) capsule daily with food or as directed by a health care professional.

Precautions

As a reminder, discuss the supplements and medications that you take with your health care providers. Caution: If you are pregnant or nursing, taking medication or planning a surgery, consult your doctor before using this product.

Stop using and consult your doctor if any adverse reactions occur. Do not accept if seal is broken.

Keep out of the reach of children.

Storage

Store in a dry place between 59 degrees - 86 degrees F.

See for yourself

Vanadyl Sulfate by Country Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Vanadyl Sulfate by Country Life

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.

Vanadium

Interacts with
208 drugs
975 mcg per serving Form: Vanadyl Sulfate

Vanadium is a trace mineral found in tiny amounts in food, and people get plenty from a normal diet. Supplement claims for diabetes, weight, and athle...

Vanadium monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Vanadyl Sulfate by Country Life Drug Interactions

Want to check YOUR meds against Vanadyl Sulfate?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Vanadium 208

Each ingredient & the kinds of drugs it affects

For each ingredient in Vanadyl Sulfate with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Vanadium2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, vanadium might increase the risk of bleeding when taken with anticoagulant/antiplatelet drugs.
In vitro research shows that the sodium orthovanadate form of vanadium prolongs clotting time, likely through inhibition of thrombin and factor Xa.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, vanadium might increase the risk of hypoglycemia when taken with antidiabetes drugs.
A few very small clinical studies in patients with type 2 diabetes show that the vanadyl sulfate form of vanadium increases insulin sensitivity and might lower blood glucose levels.

Likelihood Probable Evidence B
The maker

Brand information

Manufacturer and brand details for Vanadyl Sulfate, from the product label.

Country Life

See all Country Life products
Name
Country Life, LLC
Street Address
180 Vanderbilt Motor Parkway
City
Hauppauge
State
NY
ZipCode
11788
Web Address
CountryLifeVitamins.com
Pharmacist Counseling Corner

Vanadyl Sulfate by Country Life: Common Questions

Does Vanadyl Sulfate by Country Life interact with any medications?
Yes. Based on its ingredients, Vanadyl Sulfate has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Vanadyl Sulfate contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this really help with blood sugar?
The small studies we have suggest vanadium might lower blood glucose and improve insulin sensitivity, but we don't have enough evidence to say it's proven for treating diabetes. If you're diabetic and interested, talk to your doctor first—especially since it could lower your blood sugar further if you're already on diabetes drugs.
What dose is safe?
Vanadium is well tolerated up to 1.8 mg daily. Above that, you risk stomach problems like nausea, diarrhea, and gas. Long-term high doses carry a rare risk of kidney damage.
Can I take this while pregnant or breastfeeding?
The safety data advises against vanadium supplements during pregnancy and while breastfeeding. If you're planning to become pregnant or are nursing, skip this supplement and talk to your doctor about alternatives.
What is vanadium used for?
Vanadium deficiency—when your body doesn't get enough of this mineral—is the one use we have solid evidence for. It's been studied for athletic performance, diabetes, cancer, and high cholesterol, but the research isn't strong enough yet to say it works for those.
What are the side effects?
Most people don't have problems at the recommended dose, but higher amounts can cause stomach upset—nausea, diarrhea, gas, and belly discomfort. Allergic reactions are rare but possible and may show up as rash or itching.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Vanadyl Sulfate is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Vanadyl Sulfate label
Sources

Sources & How We Checked

Vanadyl Sulfate's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vanadium 15 references
  1. Harland BF, Harden-Williams BA. Is vanadium of human nutritional importance yet? J Am Diet Assoc 1994;94:891-4. PubMed
  2. Sitprija V, Tungsanga K, Tosukhowong P, et al. Metabolic problems in northeastern Thailand: possible role of vanadium. Mineral Electrolyte Metab 1998;19:51-6.
  3. Funakoshi T, Shimada H, Kojima S, et al. Anticoagulant action of vanadate. Chem Pharmaceut Bull 1992;40:174-6. PubMed
  4. Halberstam M, Cohen N, Shlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659-66. PubMed
  5. Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501-9. PubMed
  6. Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin-dependent diabetes mellitus. Metabolism 1996;45:1130-5.
  7. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  8. Goldfine AB, Simonson DC, Folli F, et al. Metabolic effects of sodium metavanadate in humans with insulin-dependent and noninsulin-dependent diabetes mellitus in vivo and in vitro studies. J Clin Endocrinol Metab 1995;80:3311-20. PubMed
  9. Cusi K, Cukier S, DeFronzo RA, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410-7.
  10. Peat F, Coomber R, Rana A, Vince A. Vanadium allergy following total knee arthroplasty. BMJ Case Rep 2018;2018. pii: bcr-2017-222092. doi: 10.1136/bcr-2017-222092. PubMed
  11. Jin S, Xia W, Jiang Y, et al. Urinary vanadium concentration in relation to premature rupture of membranes: A birth cohort study. Chemosphere 2018;210:1035-41. doi: 10.1016/j.chemosphere.2018.07.110. PubMed
  12. Garcia-Nunez I, Algaba-Marmol MA, Suarez-Vergara M, et al. Vanadium contact dermatitis: case report and studies performed. Contact Dermatitis 2019;80(2):127-8. PubMed
  13. Zhou Y, Zhu Q, Ma W, et al. Prenatal vanadium exposure, cytokine expression, and fetal growth: a gender-specific analysis in Shanghai MCPC study. Sci Total Environ 2019;685:1152-9. PubMed
  14. Jiang S, Zhou S, Liu H, et al. Concentrations of vanadium in urine with hypertension prevalence and blood pressure levels. Ecotoxicol Environ Saf 2021;213:112028. PubMed
  15. Zhang W, Chen H, Zeng Q, Xu S, Xia W, Li Y. Prenatal and postnatal exposure to vanadium and the immune function of children. J Trace Elem Med Biol 2021;67:126787. PubMed

See these in context on the Vanadium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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