Vegenzyme Ingredients & Drug Interactions
by R-U-Ved
What is this page for?
First and foremost: checking Vegenzyme against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Vegenzyme is a dietary supplement by R-U-Ved with 13 active ingredients. Its ingredients are commonly taken for inflammation and swelling, sinus and nasal congestion, digestion support.Based on those ingredients, 141 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bromelain. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Vegenzyme by R-U-Ved
Ask about any prescription or over-the-counter medication and we check it for interactions with Vegenzyme by R-U-Ved — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Vegenzyme by R-U-Ved
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 13 of its 13 active ingredients.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 4 matched ingredients can interact with medications — Bromelain.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
- For scale: 141 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 4 of 4.
- General safety write-ups exist for 4 of 4.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 6 of 13 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Vegenzyme, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Vegenzyme by R-U-Ved, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Amylase | 14000 SKB | -- |
| Bromelain | 9000 FCC | -- |
| Lipase | 560 LU | -- |
| Lactase | 650 LACU | -- |
| Cellulase | 200 CU | -- |
| Peptidase | 225 SP | -- |
| Invertase | 45 INVU | -- |
| Maltase | 67 DP | -- |
| Hemicellulase | 225 HSU | -- |
| Amylase II | 90 AGU | -- |
| Protease I | 50000 HUT | -- |
| Protease II | 5500 PC | -- |
| Protease III | 68 SAP | -- |
Other ingredients: Vegetarian Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Call us toll free at: 1-800-925-1371
Digestive Support
Nutritional Support For: • Digestive Aid • Metabolism of fats, • carbohydrates, and proteins • Maintaining a Healthy Weight
For more information on these herbs and research, please visit our website at www.ruved.net
Naturally Grown Himalayan Herbs In-house Manufactured to ensure Purity Third Party Tested for Heavy Metals
FDA Disclaimer Statement
Statements herein have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease or condition.
Formulation
Free from Milk, Soy, Egg and Wheat.
Vegenzyme(TM) is a fully vegetarian supplement which boosts the metabolism of fats, carbohydrates, and proteins and one of the most potent non-animal sourced enzyme products available.
Suggested/Recommended/Usage/Directions
Suggested Use: 1 Capsule three times daily or as directed by you physician.
Formula
Vegenzyme(TM) is a powerful formulation which combines the digestivee enzymes amylase, amylase II, protease I, II, and III, peptidase, lipase, cellulose, hemicellulase, lactase, maltase, invertase and bromelain.
Brand IP Statement(s)
Regular use of Vegenzyme(TM) supports restoration of digestive health by replenishing the supply of these critical enzymes and is formulated to resist acid breakdown retaining its potency in the stomach, thereby providing critical digestive support and allowing healthy weight to be maintained.
Seals/Symbols
R-U-VED(R) ancient wisdom, modern lifestyle
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Vegenzyme by R-U-Ved label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Vegenzyme by R-U-Ved
These are the 13 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Amylase
Bromelain
Interacts with141 drugs
Bromelain is a group of protein-digesting enzymes from pineapple that people take mainly for inflammation, swelling, and sinus problems. Some early st...
Bromelain monograph & interactionsLipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsCellulase
Peptidase
Invertase
Maltase
Hemicellulase
Amylase II
Protease I
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease I monograph & interactionsProtease II
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease II monograph & interactionsProtease III
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease III monograph & interactionsOther (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.
Vegenzyme by R-U-Ved Drug Interactions
Vegenzyme contains 13 ingredients, and 1 of them has known drug interactions. Altogether it interacts with 141 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Vegenzyme?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Vegenzyme interact with 141 drugs. Click any drug to see the details.
1 of the 13 ingredients in Vegenzyme interact with drugs. Each result below shows which ingredient is responsible. Bromelain
Amphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Amphotericin, Tetracycline interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Chlortetracycline interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Demeclocycline interactionDoripenemDoribax
How Doripenem interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Doripenem interactionDoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
How Doxycycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Doxycycline interactionDoxycycline HyclateActiclate, Acticlate Cap, Lymepak
How Doxycycline Hyclate interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Doxycycline Hyclate interactionDoxycycline MonohydrateErfacea
How Doxycycline Monohydrate interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Doxycycline Monohydrate interactionDoxycylineDoxychel
How Doxycyline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Doxycyline interactionEravacyclineXerava
How Eravacycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Eravacycline interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Minocycline Hydrochloride interactionOmadacycline (iv)Nuzyra
How Omadacycline (iv) interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Omadacycline (iv) interactionOmadacycline (oral)Nuzyra
How Omadacycline (oral) interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Omadacycline (oral) interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionRetapamulinAltabax, Altargo
How Retapamulin interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Retapamulin interactionTetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
How Tetracycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Tetracycline interactionTigecyclineTygacil
How Tigecycline interacts with Vegenzyme — through 1 ingredient. Tap an ingredient for the detail:
BromelainTetracycline Antibiotics Minor
Interaction Summary
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Read the full Bromelain + Tigecycline interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Vegenzyme with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bromelain
Anticoagulant/Antiplatelet Drugs
Bromelain may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
There is one case report of a patient experiencing minor bruising while taking bromelain with naproxen. Bromelain is thought to have antiplatelet activity. Whether this interaction is of concern with topical bromelain is unclear. Interference with coagulation of burn wounds has been reported in a patient receiving bromelain-based enzymatic debridement. However, observational research has found that topical bromelain debridement is not associated with increases or decreases in laboratory markers of coagulation when compared with surgical debridement.
Tetracycline Antibiotics
Theoretically, bromelain might increase levels of tetracycline antibiotics.
Laboratory research suggests that bromelain might increase the absorption of tetracycline antibiotics. However, a study in healthy adults reported no difference in tetracycline plasma levels when a 500 mg dose was taken with or without bromelain 80 mg.
Brand information
Manufacturer and brand details for Vegenzyme, from the product label.
Vegenzyme by R-U-Ved: Common Questions
Does Vegenzyme by R-U-Ved interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Vegenzyme is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Vegenzyme’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Bromelain
Interacts with 141 drugsBromelain is a group of protein-digesting enzymes from pineapple that people take mainly for inflammation, swelling, and sinus problems. Some early studies are promising, but the overall evi...
Read the full Bromelain monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographProteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph →Sources & How We Checked
Vegenzyme's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 24 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bromelain 19 references
- Nettis E, Napoli G, Ferrannini A, Tursi A. IgE-mediated allergy to bromelain. Allergy 2001;56:257-8. PubMed
- Taussig SJ, Batkin S. Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update. J Ethnopharmacol 1988;22:191-203.. PubMed
- Bradbrook ID, Morrison PJ, Rogers HJ. The effect of bromelain on the absorption of orally administered tetracycline. Br J Clin Pharmacol 1978;6:552-4. PubMed
- Bush TM, Rayburn KS, Holloway SW, et al. Adverse interactions between herbal and dietary substances and prescription medications: a clinical survey. Altern Ther Health Med 2007;13:30-5.
- Brien S, Lewith G, Walker AF, et al. Bromelain as an adjunctive treatment for moderate-to-severe osteoarthritis of the knee: a randomized placebo-controlled pilot study. QJM 2006;99:841-50. PubMed
- Mori S, Ojima Y, Hirose T, et al. The clinical effect of proteolytic enzyme containing bromelain and trypsin on urinary tract infection evaluated by double blind method. Acta Obstet Gynaecol Jpn 1972;19:147-53.
- Glaser D, Hilberg T. The influence of bromelain on platelet count and platelet activity in vitro. Platelets 2006;17:37-41. PubMed
- Heinicke R M, van der Wal L, Yokoyama M. Effect of bromelain (Ananase) on human platelet aggregation. Experientia 1972;28:844-5. PubMed
- Gailhofer, G., Wilders-Truschnig, M., Smolle, J., and Ludvan, M. Asthma caused by bromelain: an occupational allergy. Clin Allergy 1988;18(5):445-450. PubMed
- Mattei, O., Fabri, G., and Farina, G. [Occupational health experience regarding four cases of asthma due to bromelain (author's transl)]. Medicina del Lavoro 1979;70(5):404-409.
- Galleguillos, F. and Rodriguez, J. C. Asthma caused by bromelin inhalation. Clin Allergy 1978;8(1):21-24. PubMed
- Perez-Camo I, Quirce S, Duran MA, and et al. Latex allergy: evidence of cross-reactivity with papain and bromelain [abstract]. Allergy 1996;51(suppl 31):48.
- Martin GJ, Ehrenreich J, and Asbell N. Bromelain: pineapple proteases with anti-edema activity. Exp Med Surg 1962;20:227-247.
- Kasemsuk T, Saengpetch N, Sibmooh N, Unchern S. Improved WOMAC score following 16-week treatment with bromelain for knee osteoarthritis. Clin Rheumatol. 2016 Oct;35(10):2531-40. PubMed
- Kutlu Ö, DemirbaS A, Elmas ÖF, Güvenç U, Metin A. Fixed drug eruption: a new side effect of bromelain. Contact Dermatitis 2020. Online ahead of print. PubMed
- Shoham Y, Shapira E, Haik J, et al. Bromelain-based enzymatic debridement of chronic wounds: Results of a multicentre randomized controlled trial. Wound Repair Regen 2021;29(6):899-907. PubMed
- Pfister P, Garcia Wendel PD, Kim BS, et al. Coagulation side effects of enzymatic debridement in burned patients. Burns 2022. PubMed
- Hasham S, Riyat H, Fletcher A, O'Boyle CP, Alexander S. To bleed or not to bleed? Case series and discussion of haemorrhage risk with enzymatic debridement in burn injuries. Scars Burn Heal 2023;9:20595131231168333. PubMed
- Leelakanok N, Petchsomrit A, Janurai T, Saechan C, Sunsandee N. Efficacy and safety of bromelain: A systematic review and meta-analysis. Nutr Health 2023. PubMed
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC