Easy-Lax Ingredients & Drug Interactions
by R-U-Ved
What is this page for?
First and foremost: checking Easy-Lax against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Easy-Lax is a dietary supplement by R-U-Ved with 1 active ingredient.Based on those ingredients, 994 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Easy-Lax by R-U-Ved
Ask about any prescription or over-the-counter medication and we check it for interactions with Easy-Lax by R-U-Ved — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Easy-Lax by R-U-Ved
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Easy-Lax contains 4 ingredients total. The active botanical ingredients are fennel, Haritaki, Trachyspermum ammi (bishop's weed), and senna—a blend designed to support bowel regularity.
Senna is a stimulant laxative, while the others are traditional digestive herbs. The capsule itself is vegetarian.
Does it work?
Strong evidence
Senna in this product is likely effective for constipation and possibly effective for bowel preparation before medical procedures. Fennel is possibly effective for menstrual pain (dysmenorrhea), though we hold insufficient evidence for its use in anxiety or bronchitis.
We have no effectiveness ratings in our data for Haritaki or bishop's weed.
How safe is it?
Well-documented data
Fennel is generally well tolerated when used in food amounts but needs caution at medicinal doses. The most common side effects are stomach discomfort, photosensitivity (skin reaction to sun), and allergic reactions in sensitive people; seizures are rare.
Fennel is possibly unsafe during pregnancy and breastfeeding due to hormone-like effects. Bishop's weed contains light-sensitizing compounds and should only be used under medical supervision; it's likely unsafe in pregnancy and safety is unknown while breastfeeding.
Senna is generally safe for short-term occasional use but not for long-term daily use without medical advice. Common side effects include stomach cramps, diarrhea, nausea, and urine discoloration; rare serious effects include skin rashes.
We hold no pregnancy or breastfeeding safety data for Haritaki.
Meds to double-check
Moderate interaction found
Check your exact medications with the tool below, especially if you take birth control or estrogens, blood thinners (warfarin, aspirin, clopidogrel), diuretic drugs, digoxin, stimulant laxatives, drugs broken down by liver enzyme CYP3A4 (including some heart and anxiety medications), ciprofloxacin, tamoxifen, or photosensitizing drugs like tetracyclines and quinolone antibiotics.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Easy-Lax is a laxative blend best used for occasional constipation relief, not daily long-term use. If you take birth control, hormone therapy, blood thinners, diuretics, digoxin, or photosensitizing drugs—or if you're pregnant or breastfeeding—check with your pharmacist first.
Use the medication search tool below before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 10, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Easy-Lax, straight from the product label.
| Brand | R-U-Ved |
|---|---|
| Barcode (UPC) | 642392000116 |
| Net contents | 60 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Oct 10, 2014 |
| DSLD ID | 37315 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Easy-Lax by R-U-Ved, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Extracts of: | 0 NP | -- |
| Proprietary Blend (Herb/Botanical) | 500 mg | -- |
| Fennel | 0 NP | -- |
| Haritaki | 0 NP | -- |
| Trachyspermum ammi | 0 NP | -- |
| Senna | 0 NP | -- |
Other ingredients: Vegetarian Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
NUTRITIONAL DIGESTIVE SUPPORT
Naturally Grown Himalayan Herbs In-house Manufactured to ensure Purity Third Party Tested for Heavy Metals
ancient wisdom, modern lifestyle New Look. Same Ancient Formula.
Digestive Support
Brand IP Statement(s)
Easy Lax(TM) is a balanced blend of ancient Ayurvedic herbs designed to supply gentle, effective support for healthy bowel regulation and occasional constipation.
R.U.VED(R) Inc. is a subsidiary of Ayush Herbs(R) Inc.
Suggested/Recommended/Usage/Directions
Suggested Use: 1 capsule two times daily or as directed by your physician.
Precautions
DO NOT USE IF SEAL IS BROKEN.
Warning: If pregnant, consult your physician before using this or any other product.
Keep Away From Reach Of Children
FDA Statement of Identity
Non-Dairy Dietary Supplement
Formulation
Free from Milk, Soy, Egg and Wheat
Non-Dairy Dietary Supplement
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Easy-Lax by R-U-Ved label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Easy-Lax by R-U-Ved
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Extracts of:
- › Proprietary Blend (Herb/Botanical)
Other (inactive) ingredients: Vegetarian Capsule. These complete the product’s ingredient list but are not active constituents.
Easy-Lax by R-U-Ved Drug Interactions
HelloPharmacist Interaction Report
Easy-Lax by R-U-Ved contains several herbal ingredients with documented interactions with medications.
The most serious concern is fennel, which has Moderate interactions with six drug types, including estrogens and blood thinners (anticoagulants and antiplatelet drugs). Fennel may interfere with hormone replacement therapy and birth control pills due to its estrogenic activity, and it may increase bleeding risk when combined with blood thinners like warfarin or aspirin.
Read the full breakdown — every affected drug type, severity by severity
The other checked ingredient, Trachyspermum ammi (bishop's weed), also carries Moderate interactions with blood thinners, medications metabolized by liver enzyme CYP3A4 (a large group including some antianxiety drugs and heart medications), and photosensitizing drugs like certain antibiotics and antidepressants. Senna, the laxative ingredient, interacts Moderately with estrogens, diuretics, blood thinners including warfarin, heart medications like digoxin, and other stimulant laxatives—overuse raises the risk of potassium loss and bleeding.
We could not check Haritaki, as we hold no interaction data for it.
Additionally, use the medication checker on this page to look up your exact drugs before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Easy-Lax?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Easy-Lax interact with 994 drugs. Click any drug to see the details.
0 of the 1 ingredient in Easy-Lax interact with drugs. Each result below shows which ingredient is responsible.
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Ado-trastuzumab Emtansine interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Abciximab interactionTrachyspermum AmmiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has antiplatelet activity.
Read the full Trachyspermum Ammi + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abemaciclib interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abiraterone interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Abiraterone Acetate interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has antiplatelet activity.
Read the full Trachyspermum Ammi + Abrocitinib interactionFennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acalabrutinib interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acalabrutinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acenocoumarol interactionTrachyspermum AmmiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has antiplatelet activity.
Read the full Trachyspermum Ammi + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Easy-Lax — through 1 ingredient. Tap an ingredient for the detail:
Trachyspermum AmmiPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acepromazine interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has antiplatelet activity.
Read the full Trachyspermum Ammi + Acetaminophen, Aspirin interactionFennelAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
Read the full Fennel + Acetaminophen, Aspirin, Caffeine interactionTrachyspermum AmmiAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has antiplatelet activity.
Read the full Trachyspermum Ammi + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Easy-Lax — through 1 ingredient. Tap an ingredient for the detail:
Trachyspermum AmmiPhotosensitizing Drugs Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Butalbital, Caffeine interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Butalbital, Caffeine, Codeine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionTrachyspermum AmmiPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Caffeine, Codeine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Codeine, Salicylamide interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Caffeine, Dihydrocodeine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Isometheptene interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Easy-Lax — through 3 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Caffeine, Pyrilamine interactionSennaDiuretic Drugs Moderate
Interaction Summary
Theoretically, senna might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Senna + Acetaminophen, Caffeine, Pyrilamine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionTrachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylephrine interactionTrachyspermum AmmiPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
FennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionTrachyspermum AmmiPhotosensitizing Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Bishop's weed constituents seem to cause photosensitivity.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Easy-Lax — through 2 ingredients. Tap an ingredient for the detail:
Trachyspermum AmmiCytochrome P450 3a4 (cyp3a4) Substrates, Photosensitizing Drugs Moderate
Interaction Summary
Bergapten, a constituent of bishop's weed, has been shown to inhibit cytochrome P450 3A4 (CYP3A4) in vitro.
Read the full Trachyspermum Ammi + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionFennelCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, fennel might increase levels of drugs metabolized by CYP3A4.
Read the full Fennel + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Easy-Lax with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Brand information
Manufacturer and brand details for Easy-Lax, from the product label.
Easy-Lax by R-U-Ved: Common Questions
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
Easy-Lax's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 67 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Fennel 17 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Zhu M, Wong PY, Li RC. Effect of oral administration of fennel (Foeniculum vulgare) on ciprofloxacin absorption and disposition in the rat. J Pharm Pharmacol 1999;51:1391-6.
- Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
- Burkhard PR, Burkhardt K, Haenggeli CA, Landis T. Plant-induced seizures: reappearance of an old problem. J Neurol 1999;246:667-70. PubMed
- Rosti L, Nardini A, Bettinelli ME, Rosti D. Toxic effects of a herbal tea mixture in two newborns. Acta Paediatrica 1994;83:683. PubMed
- Cuzzolin L, Zaffani S, and Benoni G. Safety implications regarding use of phytomedicines. Eur.J Clin Pharmacol. 2006;62:37-42. PubMed
- Tognolini, M., Ballabeni, V., Bertoni, S., Bruni, R., Impicciatore, M., and Barocelli, E. Protective effect of Foeniculum vulgare essential oil and anethole in an experimental model of thrombosis. Pharmacol.Res 2007;56(3):254-260. PubMed
- Subehan, Usia, T., Iwata, H., Kadota, S., and Tezuka, Y. Mechanism-based inhibition of CYP3A4 and CYP2D6 by Indonesian medicinal plants. J Ethnopharmacol. 5-24-2006;105(3):449-455. PubMed
- Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
- Subehan, Zaidi, S. F., Kadota, S., and Tezuka, Y. Inhibition on human liver cytochrome P450 3A4 by constituents of fennel (Foeniculum vulgare): identification and characterization of a mechanism-based inactivator. J Agric.Food Chem. 12-12-2007;55(25):101 PubMed
- LEVY, S. B. Bronchial asthma due to ingestion of fennel and fennel seed. Ann.Allergy 1948;6(4):415.
- Ottolenghi, A., De Chiara, A., Arrigoni, S., Terracciano, L., and De Amici, M. [Diagnosis of food allergy caused by fruit and vegetables in children with atopic dermatitis]. Pediatr Med Chir 1995;17(6):525-530.
- Trabace L, Tucci P, Ciuffreda L, et al. "Natural" relief of pregnancy-related symptoms and neonatal outcomes: above all do no harm. J Ethnopharmacol. 2015;174:396-402. PubMed
- Denaxa D, Arkwright PD. Fennel as a cause of immediate hypersensitivity to toothpaste. Ann Allergy Asthma Immunol. 2020;125(1):99-100. PubMed
- Lee HW, Ang L, Lee MS, Alimoradi Z, Kim E. Fennel for reducing pain in primary dysmenorrhea: a systematic review and meta-analysis of randomized controlled trials. Nutrients 2020;12(11):3438. PubMed
- Mathew T, John SK, Javali M, Vasireddy M, Nadig R, Sarma GRK. Substance use related cluster headache: A case series. Headache 2022;62(7):908-910. PubMed
Bishop's Weed 8 references
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Kiistala R, Makinen-Kiljunen S, Heikkinen K, et al. Occupational allergic rhinitis and contact urticaria caused by bishop's weed (Ammi majus). Allergy 1999;54:635-9.
- Ossenkoppele PM, van der Sluis WG, van Vloten WA. [Phototoxic dermatitis following the use of Ammi majus fruit for vitiligo]. Ned Tijdschr Geneeskd 1991;135:478-80.
- Malhotra S, Bailey DG, Paine MF, Watkins PB. Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins. Clin Pharmacol Ther 2001;69:14-23. PubMed
- Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
- Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
- Dollahite, J. W., Younger, R. L., and Hoffman, G. O. Photosensitization in cattle and sheep caused by feeding Ammi majus (greater Ammi; Bishop's-Weed). Am J Vet.Res 1978;39(1):193-197. DOI
- Kavli, G. and Volden, G. Phytophotodermatitis. Photodermatol. 1984;1(2):65-75.
Senna 42 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- American Academy of Pediatrics. The transfer of drugs and other chemicals into human milk. Pediatrics 2001;108:776-89. PubMed
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Seybold U, Landauer N, Hillebrand S, Goebel FD. Senna-induced hepatitis in a poor metabolizer. Ann Intern Med 2004;141:650-1. PubMed
- Vanderperren B, Rizzo M, Angenot L, et al. Acute liver failure with renal impairment related to the abuse of senna anthraquinone glycosides. Ann Pharmacother 2005;39:1353-7. PubMed
- Xing JH, Soffer EE. Adverse effects of laxatives. Dis Colon Rectum 2001;44:1201-9. PubMed
- Prior J, White I. Tetany and clubbing in patient who ingested large quantities of senna. Lancet 1978;2:947. PubMed
- Langmead L, Rampton DS. Review article: herbal treatment in gastrointestinal and liver disease--benefits and dangers. Aliment Pharmacol Ther 2001;15:1239-52. PubMed
- Joo JS, Ehrenpreis ED, Gonzalez L, et al. Alterations in colonic anatomy induced by chronic stimulant laxatives: the cathartic colon revisited. J Clin Gastroenterol 1998;26:283-6. PubMed
- Godding EW. Laxatives and the special role of senna. Pharmacology 1988;36:230-6. PubMed
- van Os FH. Anthraquinone derivatives in vegetable laxatives. Pharmacology 1976;14:7-17. PubMed
- Sondheimer JM, Gervaise EP. Lubricant versus laxative in the treatment of chronic functional constipation of children: a comparative study. J Pediatr Gastroenterol Nutr 1982;1:223-6. DOI
- Perkin JM. Constipation in childhood: a controlled comparison between lactulose and standardized senna. Curr Med Res Opin 1977;4:540-3. PubMed
- Shelton MG. Standardized senna in the management of constipation in the puerperium: A clinical trial. S Afr Med J 1980;57:78-80.
- [No authors listed] Senna in the puerperium. Pharmacology 1992;44:23-5. PubMed
- Passmore AP, Davies KW, Flanagan PG, et al. A comparison of Agiolax and lactulose in elderly patients with chronic constipation. Pharmacology 1993;47:249-52. PubMed
- Passmore AP, Wilson-Davies K, Stoker C, Scott ME. Chronic constipation in long stay elderly patients: a comparison of lactulose and a senna-fibre combination. BMJ 1993;307:769-71. PubMed
- MacLennan WJ, Pooler AFWM. A comparison of sodium picosulphate ("Laxoberal") with standardised senna ("Senokot") in geriatric patients. Curr Med Res Opin. 1974;2:641-7. PubMed
- Kittisupamongkol W, Nilaratanakul V, Kulwichit W. Near-fatal bleeding, senna, and the opposite of lettuce. Lancet 2008;371:784. PubMed
- Prather CM. Pregnancy-related constipation. Curr Gastroenterol Rep 2004;6:402-4. PubMed
- Werthmann WM Jr, Krees SV. Quantitative excretion of Senokot in human breast milk. Med Ann Dist Columbia 1973;42:4-5.
- Hagemann TM. Gastrointestinal medications and breastfeeding. J Hum Lact 1998;14:259-62. PubMed
- Faber P, Strenge-Hesse A. Senna-containing laxatives: excretion in the breast milk? Geburtshilfe Frauenheilkd 1989;49:958-62.
- Faber P, Strenge-Hesse A. Relevance of rhein excretion into breast milk. Pharmacology 1988;36 Suppl 1:212-20. PubMed
- Duncan AS. Standardized senna as a laxative in the puerperium; a clinical assessment. Br Med J 1957;1:439-41. PubMed
- Stickel, F. and Schuppan, D. Herbal medicine in the treatment of liver diseases. Dig.Liver Dis. 2007;39(4):293-304. PubMed
- BALDWIN, W. F. CLINICAL STUDY OF SENNA ADMINISTRATION TO NURSING MOTHERS: ASSESSMENT OF EFFECTS ON INFANT BOWEL HABITS. Can.Med Assoc.J 9-14-1963;89:566-568. DOI
- Sonmez, A., Yilmaz, M. I., Mas, R., Ozcan, A., Celasun, B., Dogru, T., Taslipinar, A., and Kocar, I. H. Subacute cholestatic hepatitis likely related to the use of senna for chronic constipation. Acta Gastroenterol.Belg. 2005;68(3):385-387.
- Beuers, U., Spengler, U., and Pape, G. R. Hepatitis after chronic abuse of senna. Lancet 2-9-1991;337(8737):372-373. PubMed
- Lim, A. K., Hooke, D. H., and Kerr, P. G. Anorexia nervosa and senna misuse: nephrocalcinosis, digital clubbing and hypertrophic osteoarthropathy. Med J Aust. 1-21-2008;188(2):121-122. PubMed
- McLaughlin, A. F. Anorexia nervosa and senna misuse: nephrocalcinosis, digital clubbing and hypertrophic osteoarthropathy. Med J Aust. 9-15-2008;189(6):348. PubMed
- Soyuncu, S., Cete, Y., and Nokay, A. E. Portal vein thrombosis related to Cassia angustifolia. Clin.Toxicol.(Phila) 2008;46(8):774-777.
- Levine, D., Goode, A. W., and Wingate, D. L. Purgative abuse associated with reversible cachexia, hypogammaglobulinaemia, and finger clubbing. Lancet 4-25-1981;1(8226):919-920. PubMed
- Malmquist, J., Ericsson, B., Hulten-Nosslin, M. B., Jeppsson, J. O., and Ljungberg, O. Finger clubbing and aspartylglucosamine excretion in a laxative-abusing patient. Postgrad.Med J 1980;56(662):862-864. PubMed
- Lewis, S. J., Heaton, K. W., Oakey, R. E., and McGarrigle, H. H. Lower serum oestrogen concentrations associated with faster intestinal transit. Br.J Cancer 1997;76(3):395-400. PubMed
- Lewis, S. J., Oakey, R. E., and Heaton, K. W. Intestinal absorption of oestrogen: the effect of altering transit-time. Eur.J Gastroenterol.Hepatol. 1998;10(1):33-39. PubMed
- Vilanova-Sanchez A, Gasior AC, Toocheck N, et al. Are Senna based laxatives safe when used as long term treatment for constipation in children? J Pediatr Surg 2018;53(4):722-7. PubMed
- Cogley K, Echevarria A, Correa C, De la Torre-Mondragón L. Contact Burn with Blister Formation in Children Treated with Sennosides. Pediatr Dermatol 2017;34(2):e85-e88. PubMed
- Coskun Y, Yuksel I. Polyethylene glycol versus split high-dose senna for bowel preparation: A comparative prospective randomized study. J Gastroenterol Hepatol 2020;35(11):1923-1929.
- Haoudar A, Chekhlabi N, El Kettani C, Dini N. Acute Hepatitis and Pancytopenia in a Child With Chronic Abuse of Senna. Cureus 2021;13(1):e12436. PubMed
- Irazábal B, Sánchez de Vicente J, Galán C, et al. Anaphylaxis Due to Senna (Cassia angustifolia). J Investig Allergol Clin Immunol 2021;31(1):71-73. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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