Vitamin B2 100 mg Ingredients & Drug Interactions
by Solgar
What is this page for?
First and foremost: checking Vitamin B2 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Vitamin B2 100 mg is a dietary supplement by Solgar with 1 active ingredient. Its ingredients are commonly taken for riboflavin deficiency, migraine prevention, general energy and metabolism support.Based on those ingredients, 20 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin B2. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Vitamin B2 100 mg by Solgar
Ask about any prescription or over-the-counter medication and we check it for interactions with Vitamin B2 100 mg by Solgar — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Vitamin B2 100 mg by Solgar
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: vitamin B2 (riboflavin), a B vitamin at 100 mg per capsule. The remaining ingredients are inactives — vegetable cellulose, vegetable magnesium stearate, silica, and microcrystalline cellulose — which serve as the capsule and binding materials.
Does it work?
Couldn't assess
We don't hold effectiveness ratings for riboflavin in our data, so I can't tell you what the science says this dose is proven to do.
How safe is it?
Well-documented data
Riboflavin is very well tolerated, and excess is simply removed in your urine. At recommended doses, it's safe during pregnancy and breastfeeding — in fact, your body needs it at both times — but if you're pregnant or nursing and thinking about a high-dose supplement, check with your provider first.
The most common side effects are nausea and bright yellow urine at higher doses. Diarrhea is rare.
In one clinical trial, one person out of 28 taking 400 mg daily reported diarrhea and one reported increased urination, though those are much higher than the 100 mg in this product.
Meds to double-check
Moderate interaction found
If you take tetracycline antibiotics (doxycycline, tetracycline, minocycline, or related drugs), check with your pharmacist or doctor before adding this supplement — there's a moderate theoretical concern it could lower how well they work.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Vitamin B2 at this dose is a straightforward, well-tolerated supplement. The main thing to watch is if you take tetracycline antibiotics — there's a theoretical concern they might be less effective together, though it hasn't been a real-world problem.
Check your medications with the tool before you start.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Vitamin B2 100 mg, straight from the product label.
| Brand | Solgar |
|---|---|
| Barcode (UPC) | 033984030503 |
| Net contents | 100 Vegetable Capsule(s) |
| Market status | On market |
| Date entered into DSLD | May 24, 2017 |
| DSLD ID | 73713 |
| Product type | Vitamin |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Halal, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Vitamin B2 100 mg by Solgar, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Vitamin B2 | 100 mg | 7692% |
Other ingredients: Vegetable Cellulose, Vegetable Magnesium Stearate, Silica, Microcrystalline Cellulose
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Vitamin B2 (Riboflavin), is part of the group of essential nutrients known as the B-complex. B-complex vitamins, including vitamin B2, work to support and promote energy metabolism in the body. Vitamin B2 is necessary for normal cell function, and helps to maintain a healthy nervous system. It helps the body convert carbohydrates, fats and proteins into energy and supports the body during the occasional stress of daily living.
Since 1947
DV = Daily Value
Formula
This formulation offers essential B2 in a convenient vegetarian dosage form.
(Riboflavin)
Solgar’s KOF-K certification # K-1250
Brand IP Statement(s)
2017 Solgar, Inc.
General
SOLGB73050 02D
Formulation
Gluten, wheat & dairy free Non-GMO
Suitable for Vegans
Free Of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives and color.
Seals/Symbols
K Parve
GF Certified Gluten-free
M Halal
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement for adults, take one (1) vegetable capsule daily, preferably with a meal or as directed by a healthcare practitioner.
Precautions
If you are pregnant, nursing, taking any medication or have a medical condition, please consult your healthcare practitioner before taking any dietary supplement.
Discontinue use and consult your healthcare practitioner if any adverse reactions occur.
Keep out of reach of children.
Do not use if outer bottle seal is missing or damaged.
Storage
Store at room temperature.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Vitamin B2 100 mg by Solgar label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Vitamin B2 100 mg by Solgar
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Vegetable Capsule(s) Dosage formCapsule Amounts shown are per serving.
Vitamin B2
Interacts with20 drugs
Riboflavin (vitamin B2) is an essential nutrient your body needs to turn food into energy and to keep skin, eyes, and nerves healthy. It is generally...
Vitamin B2 monograph & interactionsOther (inactive) ingredients: Vegetable Cellulose, Vegetable Magnesium Stearate, Silica, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.
Vitamin B2 100 mg by Solgar Drug Interactions
HelloPharmacist Interaction Report
Solgar's Vitamin B2 100 mg contains riboflavin, which has a documented moderate interaction with tetracycline antibiotics (a class that includes doxycycline, tetracycline, and minocycline, among others).
In vitro research suggests riboflavin may reduce how well these antibiotics work, though this hasn't been reported as a clinical problem in humans yet — it's a theoretical concern based on lab studies.
Read the full breakdown — every affected drug type, severity by severity
Although this is the only interaction category we have data for, we can't say with certainty there are no others. Altogether, these interactions span 20 individual medications.
If you take a tetracycline antibiotic or any prescription medication, check your exact drugs with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Vitamin B2 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Vitamin B2 100 mg interact with 20 drugs. Click any drug to see the details.
1 of the 1 ingredient in Vitamin B2 100 mg interact with drugs. Each result below shows which ingredient is responsible. Vitamin B2
Amphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Amphotericin, Tetracycline interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionChlortetracyclineAureomycin
How Chlortetracycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Chlortetracycline interactionDemeclocyclineDeclomycin
How Demeclocycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Demeclocycline interactionDoripenemDoribax
How Doripenem interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doripenem interactionDoxycyclineDoryx, Doxy, Doxy-D, Doxycin, Doxycycline Injection, Doxylin +6 more
How Doxycycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline interactionDoxycycline HyclateActiclate, Acticlate Cap, Lymepak
How Doxycycline Hyclate interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline Hyclate interactionDoxycycline MonohydrateErfacea
How Doxycycline Monohydrate interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycycline Monohydrate interactionDoxycylineDoxychel
How Doxycyline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Doxycyline interactionEravacyclineXerava
How Eravacycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Eravacycline interactionMetronidazole, Tetracyline, Bismuth Subcitrate PotassiumPylera
How Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Metronidazole, Tetracyline, Bismuth Subcitrate Potassium interactionMinocyclineAcnamino MR, Aknemin, Amzeeq, Arestin Miscrosperes, Dynacin, Minocin +6 more
How Minocycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Minocycline interactionMinocycline HydrochlorideMinolira, Ximino
How Minocycline Hydrochloride interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Minocycline Hydrochloride interactionOmadacycline (iv)Nuzyra
How Omadacycline (iv) interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Omadacycline (iv) interactionOmadacycline (oral)Nuzyra
How Omadacycline (oral) interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Omadacycline (oral) interactionOxytetracyclineTerramycin
How Oxytetracycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Oxytetracycline interactionOxytetracycline, Phenazopyridine, SulfamethizoleUrobiotic
How Oxytetracycline, Phenazopyridine, Sulfamethizole interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Oxytetracycline, Phenazopyridine, Sulfamethizole interactionRetapamulinAltabax, Altargo
How Retapamulin interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Retapamulin interactionTetracyclineAchromycin, Achromycin V, Nor-Tet, Robitet, Sumycin, Sumycin 250 +6 more
How Tetracycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Tetracycline interactionTigecyclineTygacil
How Tigecycline interacts with Vitamin B2 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Vitamin B2Tetracycline Antibiotics Moderate
Interaction Summary
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
Read the full Vitamin B2 + Tigecycline interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Vitamin B2 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Vitamin B2
Tetracycline Antibiotics
Theoretically, taking riboflavin with tetracycline antibiotics may decrease the potency of these antibiotics.
In vitro research suggests that riboflavin may inhibit the potency of tetracycline antibiotics. It is not clear if this effect is clinically significant, as this interaction has not been reported in humans.
Brand information
Manufacturer and brand details for Vitamin B2 100 mg, from the product label.
Solgar
See all Solgar products- Name
- Solgar, Inc.
- Street Address
- 500 Willow Tree Road
- City
- Leonia
- State
- NJ
- ZipCode
- 07605
- Phone Number
- 1-877-765-4274
- Web Address
- www.solgar.com
Vitamin B2 100 mg by Solgar: Common Questions
Does Vitamin B2 100 mg by Solgar interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this give me bright yellow urine?
Is it safe to take while pregnant or breastfeeding?
What does vitamin B2 do?
Are there any fillers in this?
What if I take tetracycline antibiotics?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Vitamin B2 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Vitamin B2 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Vitamin B2 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 5 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Riboflavin 5 references
- Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology 1998;50:466-70. PubMed
- Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
- Leeson LJ, Weidenheimer JF. Stability of tetracycline and riboflavin. J Pharm Sci. 1969;58(3):355-7. PubMed
- MacLennan, S. C., Wade, F. M., Forrest, K. M., Ratanayake, P. D., Fagan, E., and Antony, J. High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial. J Child Neurol. 2008;23(11):1300-1304.
- Dietary reference intakes (DRIs): estimated average requirements. Food and Nutrition Board, Institute of Medicine, National Academics. https://www.nal.usda.gov/sites/default/files/fnic_uploads//recommended_intakes_individuals.pdf Accessed July 24, 2017.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC