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Dietary supplement

Wormwood 450 mg Ingredients & Drug Interactions

by Hildegard's Original

Wormwood 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wormwood 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wormwood 450 mg is a dietary supplement by Hildegard's Original with 1 active ingredient. Its ingredients are commonly taken for digestive upset and poor appetite, intestinal parasites, crohn's disease symptoms.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wormwood. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wormwood 450 mg by Hildegard's Original

Ask about any prescription or over-the-counter medication and we check it for interactions with Wormwood 450 mg by Hildegard's Original — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wormwood 450 mg by Hildegard's Original

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: wormwood at 450 mg per capsule. Wormwood is an herb traditionally used for various digestive and inflammatory purposes.

The capsule also contains inactive ingredients — cellulose, magnesium stearate, silica, and microcrystalline cellulose — which are fillers and binders that hold the capsule together.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Wormwood's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: promote healthy cleansing and restore mental alertness.
  • We looked for evidence on: Dyspepsia, Crohn disease, digestive health, energy and vitality, appetite stimulation.
  • The closest evidence on file: Wormwood is rated "Insufficient Reliable Evidence To Rate" for Crohn disease (Natural Medicines).
  • Also on file: Wormwood is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia.

The evidence for wormwood's effectiveness isn't well established in our data. For biliary disorders, Crohn disease, depression, dyspepsia (indigestion), and osteoarthritis, the available studies provide insufficient reliable evidence to rate whether it actually works.

If you're considering wormwood for a specific condition, talk with your pharmacist or doctor about what the current research supports.

The evidence, ingredient by ingredient Wormwood

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wormwood contains thujone, a neurotoxin that can be unsafe when taken orally in medicinal amounts — especially over the long term. The most common side effects are muscle aches, nausea, and vomiting.

Rare but serious effects include kidney damage, rhabdomyolysis (muscle breakdown), and seizures. Chronic use or high doses have historically been linked to addiction, hallucinations, tremors, paralysis, and brain damage.

The safety data advises against wormwood during pregnancy because it may stimulate the uterus. There isn't enough safety information to recommend it while breastfeeding either.

Short-term use of properly prepared products may be acceptable, but this is a decision to make with your doctor or pharmacist.

Side effects, ingredient by ingredient Wormwood

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wormwood.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take anticonvulsants (seizure medications), check with your pharmacist before starting wormwood — it may reduce how well your seizure drug works. Because wormwood may interact with up to 50 individual medications across multiple categories, run your complete medication list through our checker on this page before you begin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Wormwood may be an option for short-term use under professional guidance, but the evidence for what it actually treats is thin. If you take anticonvulsants (seizure medications), you'll want to check with us first — wormwood could interfere with them.

Pregnant people and those breastfeeding should avoid it. Talk to your pharmacist about whether this is right for you and how long it's safe to use.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 19, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wormwood 450 mg, straight from the product label.

Brand Hildegard's Original
Barcode (UPC) X002NBHWAV
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD May 19, 2022
DSLD ID 268009
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wormwood 450 mg by Hildegard's Original, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
X002NBHWAV
IngredientAmount% DV
Wormwood450 mg--

Other ingredients: Cellulose, Magnesium Stearate, Silica, Microcrystalline Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Hildegard's Original Wormwood has been passed down over centuries in Germany to promote healthy cleansing, renew energy, and restore mental alertness. We use only the finest quality ingredients, inspired by the founder of alternative medicine, Hildegard von Bingen.

Brand IP Statement(s)

Traditional remedies for modern living

Formulation

Hildegard's master of exhaustion

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommended Use: Adults take 1 capsule with 8 oz water, 1 time daily.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Herbs 01

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wormwood 450 mg by Hildegard's Original label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wormwood 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wormwood 450 mg by Hildegard's Original

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Wormwood

Interacts with
50 drugs
450 mg per serving Form: Artemisia absinthium

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It...

Wormwood monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate, Silica, Microcrystalline Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wormwood 450 mg by Hildegard's Original Drug Interactions

Want to check YOUR meds against Wormwood 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

Wormwood 50

Individual Drug Interactions

The ingredients in Wormwood 450 mg interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wormwood 450 mg interact with drugs. Each result below shows which ingredient is responsible. Wormwood

Each ingredient & the kinds of drugs it affects

For each ingredient in Wormwood 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wormwood1 drug type · 50 drugs

Anticonvulsants

Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Thujone, a constituent of wormwood, has convulsant effects.

Likelihood Possible Evidence D
Wormwood full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wormwood 450 mg, from the product label.

Hildegard's Original

See all Hildegard's Original products
Name
Eurbal Brands
Street Address
P.O. Box 100091
City
Denver
State
CO
ZipCode
80250
Phone Number
1-888-344-8703
Web Address
eurbal.com
Pharmacist Counseling Corner

Wormwood 450 mg by Hildegard's Original: Common Questions

Does Wormwood 450 mg by Hildegard's Original interact with any medications?
Yes. Based on its ingredients, Wormwood 450 mg has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wormwood 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is wormwood used for?
Wormwood has been traditionally used for various purposes, including biliary disorders, digestive issues like Crohn disease and indigestion, depression, and osteoarthritis. However, our data shows insufficient reliable evidence to confirm it actually works for any of these conditions.
Can I take this while pregnant or breastfeeding?
No. Wormwood may stimulate the uterus and is considered unsafe during pregnancy. There isn't enough safety data to recommend it while breastfeeding either. Talk with your doctor or pharmacist before using this product if you're pregnant, planning to become pregnant, or nursing.
What are the side effects?
The most common side effects are muscle aches, nausea, and vomiting. Rare but serious effects include kidney damage, muscle breakdown, and seizures. Wormwood contains thujone, a neurotoxin that can be unsafe in medicinal doses, especially over time.
Is it safe to use long-term?
No. The thujone in wormwood can be toxic in higher amounts, and chronic use has been linked to serious neurological effects including hallucinations, tremors, paralysis, and brain damage. Short-term use of properly prepared products may be acceptable, but that's a conversation to have with your pharmacist.
Why does this say it interacts with 50 medications if I only see one drug type listed?
That one drug type — anticonvulsants — represents 50 individual seizure medications across the category. Different seizure drugs may all be affected similarly by wormwood, so the total count is higher even though the category is singular.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wormwood 450 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wormwood 450 mg label
Go deeper

The Full Monographs Behind Wormwood 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wormwood

Interacts with 50 drugs

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It contains thujone, which can be toxic in...

Read the full Wormwood monograph →
Sources

Sources & How We Checked

Wormwood 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wormwood 10 references
  1. Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
  2. Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
  3. Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
  4. Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
  5. Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
  6. Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
  7. Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
  8. Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
  9. El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
  10. Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.

See these in context on the Wormwood monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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