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Dietary supplement

Wormwood Ingredients & Drug Interactions

by Hawaii Pharm

Wormwood label
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Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Wormwood against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Wormwood is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for digestive upset and poor appetite, intestinal parasites, crohn's disease symptoms.Based on those ingredients, 50 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Wormwood extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Wormwood by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Wormwood by Hawaii Pharm — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Wormwood by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: certified organic wormwood extract. Wormwood has a long history in herbal medicine, though the evidence for what it actually does is still being worked out.

The liquid form also contains vegetable palm glycerin and alcohol as inactive ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Wormwood's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: digestive and intestinal health support.
  • We looked for evidence on: Biliary disorders, Crohn disease, Dyspepsia, Gastritis, indigestion, appetite — and 2 related terms.
  • The closest evidence on file: Wormwood is rated "Insufficient Reliable Evidence To Rate" for Biliary disorders (Natural Medicines).
  • Also on file: Wormwood is rated "Insufficient Reliable Evidence To Rate" for Crohn disease, Dyspepsia, Gastritis.

The evidence we hold doesn't establish that wormwood works for any condition. We rate it as having insufficient reliable evidence for biliary disorders, Crohn disease, depression, dyspepsia, and osteoarthritis.

That doesn't mean it doesn't work—it means the research isn't solid enough yet for us to say either way.

The evidence, ingredient by ingredient Wormwood

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Wormwood contains thujone, a neurotoxin, and that's the main safety concern here. Short-term use of a properly prepared product may be okay, but thujone can be toxic at higher amounts.

Common side effects from the oil include diffuse muscle aches, nausea, and vomiting. Rarely, it can cause acute kidney toxicity, muscle breakdown (rhabdomyolysis), and seizures.

Chronic heavy use—historically seen with absinthe, an alcoholic drink containing wormwood—has been tied to addiction, hallucinations, tremors, paralysis, epilepsy, and brain damage. Wormwood is unsafe in pregnancy because it may stimulate the uterus.

There isn't enough safety data to recommend it while breastfeeding, so it's best avoided then too.

Side effects, ingredient by ingredient Wormwood

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Wormwood.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: seizure medications.
  • For scale: 50 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take wormwood, check whether you're on any anticonvulsant (seizure) medications—thujone in wormwood can potentially interfere with how they work. If you take any seizure drug, run it through the checker on this page first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Wormwood hasn't yet shown reliable evidence that it works for the conditions it's traditionally used for. If you're on anticonvulsant medication, you'll want to check with us before starting it.

Talk to your pharmacist about whether this is right for you, especially if you're pregnant, breastfeeding, or on any seizure medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wormwood, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 650905471230
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Oct 23, 2020
DSLD ID 237855
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wormwood by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
650905471230
IngredientAmount% DV
certified organic Wormwood extract970 mg--

Other ingredients: Vegetable Palm Glycerin, Alcohol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Hawaii Pharm Herbal Extract Highest quality since 2008

Made with Aloha!

Formulation

Contains no GMO, gluten, artificial colors, heavy metals, preservatives, pesticides, fertilizers.

Super concentrated liquid herbal extract. Dry herb/menstruum ratio: 1:3.

Manufactured in an FDA registered facility.

Non GMO Gluten free

Made in USA, Hawaii

Suggested/Recommended/Usage/Directions

Directions for use: Shake well before using. Take about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to 2-4 oz of juice or water up to 4 times per day.

Precautions

Warning: Keep out of the reach of children.

May have contraindications. We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing or taking any medications.

Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Formula

(Artemisia absinthium)

FDA Statement of Identity

Herbal Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

FDA Registered Facility Made in United States of America USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Wormwood by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Wormwood label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Wormwood by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic Wormwood extract

Interacts with
50 drugs
970 mg per serving

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It...

Certified organic Wormwood extract monograph & interactions

Other (inactive) ingredients: Vegetable Palm Glycerin, Alcohol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wormwood by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Wormwood?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
50Drugs
50 Moderate

Ingredients driving the most interactions

certified organic Wormwood extract 50

Individual Drug Interactions

The ingredients in Wormwood interact with 50 drugs. Click any drug to see the details.

1 of the 1 ingredient in Wormwood interact with drugs. Each result below shows which ingredient is responsible. certified organic Wormwood extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Wormwood with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Wormwood extract1 drug type · 50 drugs

Anticonvulsants

Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Thujone, a constituent of wormwood, has convulsant effects.

Likelihood Possible Evidence D
certified organic Wormwood extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Wormwood, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
City
Honolulu
State
HI
ZipCode
96815
Web Address
www.hawaiipharm.com
Pharmacist Counseling Corner

Wormwood by Hawaii Pharm: Common Questions

Does Wormwood by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Wormwood has a known interaction with 50 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wormwood contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is wormwood safe during pregnancy?
No. Wormwood is considered unsafe in pregnancy because it may stimulate the uterus. If you're pregnant or planning to become pregnant, don't use this product.
Can I take wormwood while breastfeeding?
There isn't enough safety information available, so it's best to avoid wormwood while breastfeeding. Talk to your doctor or pharmacist if you're considering it.
What are the side effects of wormwood?
The most common side effects from wormwood oil are muscle aches, nausea, and vomiting. Rarely, it can cause serious effects like acute kidney toxicity, muscle breakdown, and seizures. Long-term heavy use has been linked to hallucinations, tremors, and brain damage.
Does wormwood actually work for anything?
We don't have solid evidence yet that wormwood works for the conditions it's traditionally used for—like digestive issues, arthritis, or Crohn disease. The research just isn't strong enough to say either way.
Why does wormwood contain thujone, and is it dangerous?
Thujone is a naturally occurring compound in wormwood; it's a neurotoxin. In medicinal amounts, it can be unsafe—that's why properly prepared, short-term use is important, and why we caution against it altogether in pregnancy and breastfeeding.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wormwood is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wormwood label
Go deeper

The Full Monographs Behind Wormwood’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Wormwood

Interacts with 50 drugs

Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It contains thujone, which can be toxic in...

Read the full Wormwood monograph →
Sources

Sources & How We Checked

Wormwood's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Wormwood 10 references
  1. Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
  2. Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
  3. Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
  4. Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
  5. Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
  6. Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
  7. Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
  8. Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
  9. El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
  10. Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.

See these in context on the Wormwood monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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