Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Zanthoxylum Cla. Southern Prickly Ash Ingredients & Drug Interactions

by Wise Woman Herbals

Zanthoxylum Cla. Southern Prickly Ash label
See full label image
Liquid Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Zanthoxylum Cla. Southern Prickly Ash against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Zanthoxylum Cla. Southern Prickly Ash is a dietary supplement by Wise Woman Herbals with 1 active ingredient. Its ingredients are commonly taken for toothache and mouth pain, indigestion and sluggish digestion, rheumatism and joint pain.Based on those ingredients, 36 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Southern Prickly Ash. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals

Ask about any prescription or over-the-counter medication and we check it for interactions with Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (0.50 mL) without saying how much of each component you get.

This liquid contains one active ingredient: Southern Prickly Ash (Hercules club). The other ingredients are organic alcohol and spring water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Hercules Club product and its label doesn't state a use — see Hercules Club's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness data for Southern Prickly Ash in our records, so we cannot tell you what this ingredient is intended to do or how well it works.

The evidence, ingredient by ingredient Hercules Club

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Southern Prickly Ash has limited safety data available, and the manufacturer advises using it only under professional guidance. The safety notes flag it as likely unsafe in pregnancy and possibly unsafe while breastfeeding — talk with your doctor or pharmacist before taking this product if you are pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Hercules Club

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hercules Club.
  • The most serious interaction on file is rated Minor.
  • For scale: 36 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take H2-blockers (like famotidine), antacids, or proton pump inhibitors (PPIs, such as omeprazole), check your exact medications with the tool on this page before using Southern Prickly Ash. All three drug types may become less effective if taken together.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Only minor medication interactions are documented, and some safety-information gaps remain.

Southern Prickly Ash is a single-ingredient herbal liquid with a narrow but real interaction risk: if you take H2-blockers, antacids, or PPIs for stomach acid, you'll want to check with your pharmacist first. The safety data is thin, and pregnancy and breastfeeding are situations to avoid it.

A conversation with your pharmacist or herbalist before starting is a good idea.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 24, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Zanthoxylum Cla. Southern Prickly Ash, straight from the product label.

Brand Wise Woman Herbals
Barcode (UPC) 748840017337
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD May 24, 2023
DSLD ID 284966
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Drop(s)
Maximum serving Sizes:
10 Drop(s)
Servings per container
120
UPC/BARCODE
748840017337
IngredientAmount% DV
Proprietary Blend0.5 mL--
Southern Prickly Ash0 NP--

Other ingredients: organic Alcohol, spring Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Shake well. Add 2-10 drops to water, 1-3 times per day.

Formulation

The presence of particulate matter in this product is normal.

Precautions

Caution: Not recommended during pregnancy.

Keep out of the reach of children.

General Statements

Botanical formula

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry area away from direct sunlight with the lid tightly sealed.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Zanthoxylum Cla. Southern Prickly Ash label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Drop(s) Dosage formLiquid Servings per container120 Amounts shown are per serving.

Proprietary Blend

0.5 mL per serving

Other (inactive) ingredients: Organic Alcohol, Spring Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals Drug Interactions

Want to check YOUR meds against Zanthoxylum Cla. Southern Prickly Ash?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
36Drugs
36 Minor

Ingredients driving the most interactions

Southern Prickly Ash 36

Individual Drug Interactions

The ingredients in Zanthoxylum Cla. Southern Prickly Ash interact with 36 drugs. Click any drug to see the details.

1 of the 1 ingredient in Zanthoxylum Cla. Southern Prickly Ash interact with drugs. Each result below shows which ingredient is responsible. Southern Prickly Ash

Each ingredient & the kinds of drugs it affects

For each ingredient in Zanthoxylum Cla. Southern Prickly Ash with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Southern Prickly Ash3 drug types · 36 drugs

Antacids

Theoretically, Hercules club may decrease the clinical effects of antacids.
Due to reports that Hercules club increases stomach acid, Hercules club might decrease the effectiveness of antacids.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, Hercules club may decrease the clinical effects of H2 blockers.
Due to reports that Hercules club increases stomach acid, Hercules club might decrease the effectiveness of H2-blockers.

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, Hercules club may decrease the clinical effects of PPIs.
Due to reports that Hercules club increases stomach acid, Hercules club might decrease the effectiveness of PPIs.

Likelihood Possible Evidence D
Southern Prickly Ash full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Zanthoxylum Cla. Southern Prickly Ash, from the product label.

Wise Woman Herbals

See all Wise Woman Herbals products
Name
Wise Woman Herbals
City
Creswell
State
OR
ZipCode
97426
Phone Number
541.895.5152
Web Address
wisewomanherbals.com
Pharmacist Counseling Corner

Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals: Common Questions

Does Zanthoxylum Cla. Southern Prickly Ash by Wise Woman Herbals interact with any medications?
Yes. Based on its ingredients, Zanthoxylum Cla. Southern Prickly Ash has a known interaction with 36 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Zanthoxylum Cla. Southern Prickly Ash contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant or breastfeeding?
No. Southern Prickly Ash is rated likely unsafe in pregnancy and possibly unsafe while breastfeeding. The safety data advises against it in both situations. Talk with your doctor or pharmacist before use if you are pregnant, planning pregnancy, or nursing.
What is Southern Prickly Ash used for?
We don't hold effectiveness information for this ingredient in our data, so I can't tell you what it's intended to treat or support. Your herbalist or the product label may have more details on its traditional or intended uses.
Are there any side effects I should know about?
Adverse effects are not documented in our data. The main caution is that limited safety data exist overall, so professional guidance is recommended before use.
What are the inactive ingredients?
The formula contains organic alcohol and spring water as the inactive base.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Zanthoxylum Cla. Southern Prickly Ash is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Zanthoxylum Cla. Southern Prickly Ash label
Go deeper

The Full Monographs Behind Zanthoxylum Cla. Southern Prickly Ash’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hercules Club

Interacts with 36 drugs

Hercules Club (southern prickly ash) is a traditional folk remedy used mainly for toothache, digestion, and joint pain, often by chewing the bark, which causes a tingling, numbing feeling in...

Read the full Hercules Club monograph →
Sources

Sources & How We Checked

Zanthoxylum Cla. Southern Prickly Ash's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hercules Club 2 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

See these in context on the Hercules Club monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team