LYEON Anti-itch Cream HYDROCORTISONE .01 g/g Cream
🆔 Identity & classification
Where does this data come from?
🏷️ RxNorm drug class
This medicine belongs to the Corticosteroid class.
Where does this data come from?
🏭 Manufacturer & labeler
Where does this data come from?
🩺 Clinical
Hydrocortisone topical is used to treat redness, swelling, itching, and discomfort of various skin conditions. Hydrocortisone is in a class of medications called corticosteroids. It works by activating natural substances in the skin to reduce swelling, redness, and itching.
Read the full MedlinePlus article ↗- It's designed to calm down inflammation — so the redness, swelling, and itching that come with conditions like eczema should ease up, usually within a few days of consistent use. I...
- What exactly is this cream supposed to do for my skin?
- That's a really important question. Hydrocortisone is generally meant for short courses — typically a few weeks. Long-term or widespread use can cause side effects like skin thinni...
- How long can I keep using it? Is it okay to use every day long-term?
Patient education
Supplement & herbal interactions
Some supplements/herbs that may interact with Hydrocortisone — tap one for details:
Hydrocortisone may be associated with lower levels of 8 nutrients — worth a chat with your pharmacist, not a cause for alarm.
Where does this data come from?
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII TR046Y3K1G
A liquid alcohol derived from petroleum or plant sources. It acts as a solvent and humectant in medicines, helping dissolve active ingredients and retain moisture in the formulation.
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UNII YY2HMJ9NZF
A synthetic polymer made from acrylic compounds that forms a thick, gel-like substance. It's used as a thickener and stabilizer in topical products to create the right consistency and help ingredients stay evenly mixed.
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UNII 344S277G0Z
Allantoin is a naturally derived compound that helps soften and soothe skin. In medicines, it works as a skin-conditioning agent and may help support wound healing and reduce irritation in topical formulations.
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UNII QN83US2B0N
Ascorbyl palmitate is a fat-soluble form of vitamin C used as an antioxidant in medicines. It prevents oils and fats in the product from breaking down and becoming less stable over time.
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UNII 3XUS85K0RA
Butylene glycol is a clear liquid derived from petroleum or plants that acts as a humectant, solvent, and preservative booster in medicines. It helps keep formulations stable, dissolve active ingredients, and maintain moisture in topical products.
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UNII 5TJD82A1ET
A cooling crystalline substance made synthetically that is added to medicines as a fragrance, flavoring agent, and mild local irritant to produce a cooling or warming sensation on the skin or mucous membranes.
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UNII 4YS74Q4G4J
A plant extract from Centella asiatica containing natural compounds called triterpenoids. It's used as an active ingredient in some formulations for its purported skin-supporting properties, though it functions as a botanical additive rather than a structural component of the medicine.
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UNII 8FA93U5T67
A waxy substance made from plant oils that acts as an emulsifier and thickener. It helps mix oil and water components in the medicine and gives the product a smooth texture.
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UNII 936JST6JCN
Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
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UNII CI71S98N1Z
A mineral salt containing potassium and phosphate, used as a buffer to help maintain the medicine's pH level and stability during storage.
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UNII 92RU3N3Y1O
Dimethicone is a silicone-based oil that acts as an anti-foaming agent and lubricant in medicines. It reduces gas bubbles in liquid formulations and helps coat and protect the stomach lining when ingested.
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UNII 2865993309
Ethylhexyl palmitate is an oily chemical made from palm oil and alcohol. It acts as an emollient and skin-conditioning agent in topical medicines, helping the product spread smoothly and keeping skin soft.
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UNII 147D247K3P
Ethylhexylglycerin is a synthetic preservative used to prevent bacteria and mold from growing in medicines and personal care products. It helps keep the product safe and stable throughout its shelf life.
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UNII PDC6A3C0OX
Glycerin is a clear, thick liquid derived from plant oils or fats. It acts as a humectant to retain moisture, a sweetener, and a solvent in medications.
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UNII TM2TZD4G4A
A plant-derived oily substance used as an emulsifier and solubilizer in medicines. It helps blend water and oil-based ingredients together and improves how the body absorbs certain active drugs.
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UNII 230OU9XXE4
A waxy substance made from glycerin and stearic acid that acts as an emulsifier to blend oily and watery ingredients together. It also helps thicken and stabilize the medicine's texture.
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UNII G1L3HT4CMH
A synthetic compound used in medicines as a preservative and antimicrobial agent. It helps prevent bacterial and fungal growth, extending the product's shelf life.
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UNII 25KRT26H77
A synthetic organic compound used as a preservative and antioxidant in medicines. It helps prevent breakdown and spoilage of the active ingredients during storage.
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UNII 3K209OP33H
A beneficial bacterium added to support gut health and digestion. It acts as a probiotic, helping maintain healthy intestinal bacteria balance in the product formulation.
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UNII L7T10EIP3A
A cooling compound from mint plants used as a flavoring agent and to create a fresh sensation in medicines. It helps mask bitter tastes and improve how the product feels in the mouth.
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UNII T5L8T28FGP
Mineral oil is a clear, odorless liquid derived from crude oil. It acts as a lubricant and emollient in medications, helping pills slide smoothly during manufacturing and aiding moisture retention in topical products.
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UNII Z6J799EAJK
Oat is a cereal grain used in medicines as a filler and binder. It helps give the medication its shape and structure while adding bulk to the formulation.
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UNII 50C1307PZG
Pentylene glycol is a humectant and preservative helper derived from petroleum or plant sources. It draws moisture into the product and helps prevent bacterial growth, keeping medicines stable during storage.
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UNII C4QT53N4MK
Potassium lauryl phosphate is a synthetic surfactant derived from lauric acid and phosphoric acid. It helps disperse and stabilize ingredients in liquid formulations, improving how the medicine mixes and stays uniform.
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UNII 969IQC5YJU
A natural plant extract from the rugosa rose flower. It's used in formulations as a fragrance, flavor, or natural colorant to improve the taste, smell, or appearance of the medicine.
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UNII 4ELV7Z65AP
Stearic acid is a fatty acid derived from plant or animal sources. It acts as a binder and lubricant in tablets and capsules, helping them hold together and flow smoothly during manufacturing.
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UNII 2KR89I4H1Y
Stearyl alcohol is a waxy, fatty substance derived from natural oils or made synthetically. It acts as an emulsifier and thickener in medicines, helping mix ingredients together and give the product the right texture.
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UNII 9O3K93S3TK
Trolamine is an alkaline compound used as a pH buffer and emulsifier in medicines. It helps neutralize acids, stabilize formulations, and enable mixing of oil and water-based ingredients.
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UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
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UNII TTV12P4NEE
Xanthan gum is a thickening and stabilizing ingredient made from fermented corn or other sugars. It's added to medicines to improve texture, prevent separation of liquids and solids, and help the product stay consistent.
30 inactive ingredients listed in the exact product block matched to this NDC.
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
Why might an inactive ingredient be missing?
Can inactive ingredients matter?
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | Not in the retail survey — common for institutional, discontinued, or low-volume packs. | |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
Where does this data come from?
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| Leader Hydrocortisone With Aloe .01 g/g 70000-0543-01 | LEADER | 1 tube | $0.056 | — | FDA listed | — |
| Rugby Hydrocortisone With Aloe .01 g/g 50090-5470-00 | A-S | 1 tube | — | — | FDA listed | — |
| Herb Street Anti-Itch Stick .01 g/g 10107-0429-02 | Balassa | 1 tube | — | — | FDA listed | — |
| Xpect Hydrocortisone .01 g/g 42961-0237-02 | Cintas | 10 packets | — | — | FDA listed | — |
| Gembooxt ECZEMA RELIEF Cream .01 g/g 76986-0019-01 | Guangdong | 2 bottles | — | — | FDA listed | — |
| Aquanil HC .01 g/g 00096-0732-04 | Person | 118 g | — | — | FDA listed | — |
| CAREALL Hydrocortisone Maximum Strength .01 g/g 51824-0098-14 | New | 144 packets | — | — | FDA listed | — |
| CAREALL Hydrocortisone Maximum Strength .01 g/g 51824-0197-02 | New | 72 tubes | — | — | FDA listed | — |
| Natureplex Hydrocortisone Hydro .01 g/g 67234-0010-01 | Natureplex, | 28 g | — | — | FDA listed | — |
| Equate Hydrocortisone Topical .01 g/g 79903-0091-01 | WalMart | 1 tube | — | — | FDA listed | — |
| Hydrocortisone Anti-Itch .01 g/g 52000-0022-37 | Universal | 1 tube | — | — | Discontinued | — |
| Aquanil HC .01 g/g 00096-0810-04 | Person | 118 g | — | — | FDA listed | — |
| CAREALL Hydrocortisone Maximum Strength .01 g/g 51824-0097-01 | New | 28 g | — | — | FDA listed | — |
| LYEON Anti-itch Cream .01 g/gthis 87681-0008-01 | Guangzhou | 2 bottles | — | — | FDA listed | — |
| CAREALL Hydrocortisone Maximum Strength .01 g/g 51824-0114-01 | New | 28 g | — | — | FDA listed | — |
Where does this data come from?
⏳ Availability & generic status
FDA-approved generic versions are listed, and recent pricing/market data suggests they may be available — see Therapeutic equivalents.
Where does this data come from?
📊 Medicare Part D spend CMS · PART D · 2026 (Q1)
🔬 Reported adverse events (FAERS)
Top reported reactions
Age at onset
Reporter sex
Serious outcomes
Where does this data come from?
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 87681-0008-01 You're viewing this | 2 BOTTLE in 1 BOX (87681-008-01) / 15 g in 1 BOTTLE | 2026-07-16 | Active |
🧭 About this NDC listing & data coverage
What data is (and isn’t) available for this NDC — tap to expand
| NDC identity (package / product / labeler codes) | ✓ Available |
| Labeler | ✓ Available |
| Product & package description | ✓ Available |
| Marketing category & status | ✓ Available |
| Active ingredient / dosage form / route | ✓ Available |
| FDA label (SPL via DailyMed) | ✓ Available |
| Package photos | — Not published for this NDC No photo available yet for this listing. |
| Inactive ingredients (structured) | ✓ Available |
| NADAC pharmacy acquisition price (CMS) | — Not published for this NDC CMS publishes NADAC only for NDCs reported in its retail-pharmacy survey. |
| Orange Book / therapeutic-equivalence data | — Not published for this NDC Applies only to products approved under an NDA/ANDA; many listings are out of scope. |
| HCPCS J-code billing crosswalk | — Not published for this NDC Most self-administered / retail products have no J-code — that is normal. |
| Medicaid utilization (CMS SDUD) | — Not published for this NDC CMS reports utilization only for NDCs with Medicaid claims above its privacy threshold. |
Questions about this listing
Is this NDC FDA-approved?
Why is there no price listed?
Is the NDC printed on the package the same as the 11-digit billing NDC?
What do the three segments of this NDC mean?
Is this package still being marketed?
Who lists this product with the FDA?
Do I need a prescription for this product?
Where does this data come from?
📄 FDA label — Drug Facts FDA SPL
🎯 Indications and Usage ▾
TEMPORARILY RELIEVES THE ITCHING AND DISCOMFORT ASSOCIATED WITH MINOR SKIN IRRITATIONS, RASHES, AND INFLAMMATION, AND DUE TO ECZEMA. OTHER USES OF THIS PRODUCT SHOULD ONLY BE UNDER THE ADVICE AND SUPERVISION OF A DOCTOR.
⏱️ Dosage and Administration ▾
ADULTS AND CHILDREN 2 YEARS OF AGE AND OLDER: APPLY A THIN LAYER TO AFFECTED AREA NOT MORE THAN 3 TO 4 TIMES DAILY. CHILDREN UNDER 2 YEARS OF AGE: ASK A DOCTOR.
⚠️ Warnings ▾
FOR EXTERNAL USE ONLY. ASK A DOCTOR BEFORE USE IF PREGNANT OR NURSING.
🧪 Active Ingredient ▾
HYDROCORTISONE (1%)
🧪 Inactive Ingredients ▾
WATER CETYL ALCOHOL STEARYL ALCOHOL GLYCERYL STEARATE GLYCERIN MINERAL OIL CETEARETH-25 STEARIC ACID ETHYLHEXYL PALMITATE CAMPHOR MENTHOL CENTELLA ASIATICA EXTRACT AVENA SATIVA (OAT) KERNEL EXTRACT ROSA RUGOSA FLOWER EXTRACT LACTOBACILLUS FERMENT BUTYLENE GLYCOL DIMETHICONE GLYCERYL CAPRYLATE HYDROXYACETOPHENONE ETHYLHEXYLGLYCERIN 1,2-HEXANEDIOL TRIETHANOLAMINE ALLANTOIN ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER XANTHAN GUM BUTYLENE GLYCOL PENTYLENE GLYCOL HYDROXYPHENYL PROPAMIDOBENZOIC ACID ASCORBYL PALMITATE POTASSIUM LAURYL PHOSPHATE DIPOTASSIUM PHOSPHATE
🎯 Purpose ▾
ANTI-ITCH