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Diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream — RxCUI 1087026

RxNorm drug concept · Semantic clinical drug
RxCUI 1087026 Semantic clinical drug · SCD ● Current RxNorm concept 39 FDA products 42 package NDCs Snapshot Jul 14, 2026

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Compiled from public NLM RxNorm and FDA (openFDA NDC directory) data sources. Editorial policy

What you’re looking at: the standardized identity of one medicine, as the U.S. drug-data system sees it. Below — every FDA-listed product, package code, price benchmark, and billing code that maps to it.

🗂️ Key Facts

RxCUI1087026
Official nameDiphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream
Concept typeSemantic clinical drug (SCD)
RxNorm statusCurrent RxNorm concept
Also known asdiphenhydramine hydrochloride 2 % / zinc acetate 0.1 % Topical Cream; diphenhydrAMINE HCl 2 % / zinc acetate 0.1 % Topical Cream
FDA products mapped39
Package NDCs mapped42
Reported Medicaid activity (SDUD)1,470 prescriptions · 11 state & territory Medicaid programs · latest period Q4 2025
RxNorm release07/06/2026
Snapshot dataJul 14, 2026

📖 Skip the Codes — Read It in Plain English.

Our pharmacist-built guide to Diphenhydramine Topical: what it is, how it’s used, side effects, and interactions.

📗 Our plain-language guide HelloPharmacist
  • You can use it for temporary relief of pain and itching from everyday skin problems — things like insect bites, minor burns, minor cuts and scrapes, and general skin irritations. I...
  • What can I actually use this cream or spray for?
  • You can apply it up to 3 to 4 times a day, but no more than that. More frequent use isn't going to help more — and the label is clear that you shouldn't exceed that limit. For kids...
  • This is really important — do not use this topical product at the same time as any other product that contains diphenhydramine, even a pill or capsule. That includes allergy medici...
📖 Read our full Diphenhydramine Topical guide →

🕸️ Concept Web — How Diphenhydramine hydrochloride 20 MG/ML / zinc ac... Connects

One RxCUI never lives alone. Follow the path from the raw ingredient down to the exact strength-and-form concepts FDA products carry — every stop is a real RxNorm concept with its own identifier. Hover or focus any chip for what it means.
This page's concept Diphenhydramine hydrochloride 20 MG/ML / zinc acetate 1 MG/ML Topical Cream RxCUI 1087026

Every web starts here: one RxCUI, one fixed meaning in the RxNorm vocabulary.

  1. Ingredients 4

    The active substance itself — no strength, form, or brand attached yet.

    • Diphenhydramine 3498
    • Zinc acetate 58295
    • Diphenhydramine / zinc acetate 466522
    • Diphenhydramine hydrochloride 1362
  2. Brand names 3

    The same medicine's trade names. A brand name alone says nothing about strength or form.

    • Banophen Cream 1092425
    • Benadryl Itch Stopping 607032
    • Wal-Dryl 1053139
  3. Dose forms 15

    The ingredient poured into a form — tablet, solution, cream — still without one fixed strength.

    • Diphenhydramine / zinc acetate Topical Cream 377686
    • Diphenhydramine hydrochloride / zinc acetate Topical Cream 2647537
    • Diphenhydramine / zinc acetate Topical Product 1158436
    • Diphenhydramine hydrochloride / zinc acetate Topical Product 2659163
    • Diphenhydramine / zinc acetate Topical Cream [Banophen Cream] 1092427
    • Diphenhydramine / zinc acetate Topical Cream [Benadryl Itch Stopping] 708069
    • Diphenhydramine / zinc acetate Topical Cream [Wal-Dryl] 1087029
    • Diphenhydramine hydrochloride / zinc acetate Topical Cream [Banophen Cream] 2654898
    • +7 more in this family
  4. Clinical & branded drugs 8

    Ingredient + strength + dose form. These are the concepts real FDA products actually carry.

Showing up to 8 concepts per family — 23 of 30 stored related concepts drawn.
These are official RxNorm vocabulary relationships — how concepts name and organize the same medicine. They do not establish therapeutic equivalence or substitutability: two concepts appearing in one web is never a statement that products can be swapped.

🔀 Generic ⇄ Brand Crosswalk

The same medicine has an unbranded (generic) identity and one or more brand-name identities — each with its own RxCUI. This is a naming relationship in RxNorm, not a statement that any two products are substitutable.

Generic (Clinical) Concepts

  • Diphenhydramine hydrochloride 20 MG/ML SCDC · 1049097
  • Zinc acetate 1 MG/ML SCDC · 340184
  • Diphenhydramine / zinc acetate Topical Cream SCDF · 377686
  • Diphenhydramine hydrochloride / zinc acetate Topical Cream SCDFP · 2647537
  • Diphenhydramine / zinc acetate Topical Product SCDG · 1158436
  • Diphenhydramine hydrochloride / zinc acetate Topical Product SCDGP · 2659163

Brand-Name Concepts

📦 FDA Products & Package NDCs

39 products · 42 package NDCs
42 package NDCs map to RxCUI 1087026 in the current snapshot — up to 50 per page. Each linked NDC opens its full package page.
Package NDC Package Brand / generic name Labeler Marketing start
00113-0622-64 1 TUBE in 1 CARTON (0113-0622-64) / 28 g in 1 TUBE good sense itch relief L. Perrigo Company 2006-07-18
00363-2315-28 1 TUBE in 1 CARTON (0363-2315-28) / 28 g in 1 TUBE Walgreens Anti Itch Cream Walgreens Company 2014-05-05
00904-5354-31 1 TUBE in 1 CARTON (0904-5354-31) / 28 g in 1 TUBE Banophen Major Pharmaceuticals 2009-06-19
11527-0069-04 1 TUBE in 1 CARTON (11527-069-04) / 35 g in 1 TUBE Dr. Sheffield Anti Itch Cream Sheffield Pharmaceuticals LLC 2008-11-11
11673-0895-28 1 TUBE in 1 CARTON (11673-895-28) / 28 g in 1 TUBE Anti-itch Target Corporation 2024-01-31
11822-6614-01 1 TUBE in 1 CARTON (11822-6614-1) / 28 g in 1 TUBE Rite Aid Extra Strength Itch Stopping Rite Aid 2023-10-01
21130-0154-64 1 TUBE in 1 CARTON (21130-154-64) / 28 g in 1 TUBE signature care itch relief Safeway 2015-09-01
24385-0210-03 1 TUBE in 1 CARTON (24385-210-03) / 28.4 g in 1 TUBE Anti-Itch Amerisource Bergen 2005-09-20
30142-0582-64 1 TUBE in 1 CARTON (30142-582-64) / 28 g in 1 TUBE anti itch Kroger Company 2017-03-30
37012-0089-02 1 TUBE in 1 CARTON (37012-089-02) / 28.4 g in 1 TUBE Shopko Anti-Itch Shopko Stores Operating Co., LLC 2005-09-20
37808-0622-64 1 TUBE in 1 CARTON (37808-622-64) / 28 g in 1 TUBE itch relief H E B 2010-09-15
41226-0888-02 1 TUBE in 1 CARTON (41226-888-02) / 28 g in 1 TUBE Anti-Itch Cream Kroger 2025-11-15
41250-0622-64 1 TUBE in 1 CARTON (41250-622-64) / 28 g in 1 TUBE Anti Itch Meijer Distribution Inc 2010-03-17
45802-0358-03 1 TUBE in 1 CARTON (45802-358-03) / 28 g in 1 TUBE diphenhydramine hcl and zinc acetate Padagis Israel Pharmaceuticals Ltd 2005-12-05
46122-0804-36 1 TUBE in 1 CARTON (46122-804-36) / 1 g in 1 TUBE GNP Extra Strength Anti-Itch Cream Amerisource Bergen 2025-06-01
49035-0622-64 1 TUBE in 1 CARTON (49035-622-64) / 28 g in 1 TUBE Equate Anti Itch Wal-Mart Stores Inc 2010-03-17
51672-2089-02 1 TUBE in 1 CARTON (51672-2089-2) / 28.4 g in 1 TUBE Diphenhydramine Hydrochloride and Zinc Acetate Sun Pharmaceutical Industries, Inc. 2005-09-20
51824-0088-01 35 g in 1 TUBE (51824-088-01) CAREALL Anti-Itch New World Imports, Inc 2022-07-01
52000-0071-04 1 TUBE in 1 CARTON (52000-071-04) / 35.4 g in 1 TUBE (52000... Extra Strength Itch Stopping Universal Distribution Centre LLC 2021-01-21
53943-0258-01 1 TUBE in 1 CARTON (53943-258-01) / 28 g in 1 TUBE Discount Drug Mart Extra Strength Itch Stopping Discount Drug Mart 2014-03-17
55621-0007-01 1 TUBE in 1 BOX (55621-007-01) / 28 g in 1 TUBE Family Wellness Zhejiang Jingwei Pharmaceutical Co., Ltd. 2013-11-01
57237-0352-28 1 TUBE in 1 CARTON (57237-352-28) / 28 g in 1 TUBE ItchZap Rising Pharma Holdings, Inc. 2025-11-06
59779-0708-64 1 TUBE in 1 CARTON (59779-708-64) / 28 g in 1 TUBE Itch Relief CVS Pharmacy 2005-06-08
68016-0163-01 1 TUBE in 1 BOX (68016-163-01) / 28 g in 1 TUBE Itch Relief Cream Pharmacy Value Alliance LLC 2016-09-01
69396-0025-05 1 TUBE in 1 BOX (69396-025-05) / 15 g in 1 TUBE Anti-Itch Cream Trifecta Pharmaceuticals USA, LLC. 2016-12-29
69396-0025-15 1 TUBE in 1 BOX (69396-025-15) / 42 g in 1 TUBE Anti-Itch Cream Trifecta Pharmaceuticals USA, LLC. 2020-02-11
69396-0150-01 1 TUBE in 1 BOX (69396-150-01) / 28.3 g in 1 TUBE Itch stopping Cream Trifecta Pharmaceuticals USA, LLC. 2023-11-29
69452-0449-37 1 TUBE in 1 CARTON (69452-449-37) / 35.4 g in 1 TUBE itch relief Bionpharma Inc. 2024-07-16
69571-0005-02 1 TUBE in 1 BOX (69571-005-02) / 28 g in 1 TUBE (69571-005-... Family Wellness FRONT PHARMACEUTICAL PLC 2017-03-29
69842-0321-28 1 TUBE in 1 CARTON (69842-321-28) / 28 g in 1 TUBE CVS Extra Strength Itch Stopping CVS 2014-03-17
69842-0321-56 1 TUBE in 1 CARTON (69842-321-56) / 56 g in 1 TUBE CVS Extra Strength Itch Stopping CVS 2014-03-17
69968-0223-01 1 TUBE in 1 CARTON (69968-0223-1) / 28.3 g in 1 TUBE Benadryl Extra Strength Itch Stopping Kenvue Brands LLC 2009-11-01
69968-0223-02 28.3 g in 1 TUBE (69968-0223-2) Benadryl Extra Strength Itch Stopping Kenvue Brands LLC 2009-11-01
69968-0711-09 1 KIT in 1 PACKAGE (69968-0711-9) * 1 TUBE in 1 CARTON (69... Johnson and Johnson All Purpose First Aid Kit Kenvue Brands LLC 2021-08-16
69968-0726-09 1 KIT in 1 PACKAGE (69968-0726-9) * 1 CLOTH in 1 PACKET *... Johnson and Johnson First Aid All Purpose 160 CT Kenvue Brands LLC 2022-01-31
70000-0388-01 1 TUBE in 1 CARTON (70000-0388-1) / 28 g in 1 TUBE leader anti itch Cardinal Health 110, LLC. dba Leader 2018-12-13
70677-1213-01 1 TUBE in 1 CARTON (70677-1213-1) / 28.4 g in 1 TUBE Diphenhydramine Hydrochloride and Zinc Acetate STRATEGIC SOURCING SERVICES LLC 2023-12-13
70677-1289-01 1 TUBE in 1 CARTON (70677-1289-1) / 28 g in 1 TUBE foster and thrive anti itch cream Strategic Sourcing Services LLC 2025-04-30
71101-0014-01 1 TUBE in 1 CARTON (71101-014-01) / 35.4 g in 1 TUBE TheraCare 2% Diphenhydramine Anti-Itch Cream Veridian Healthcare 2025-10-01
71101-0055-01 1 TUBE in 1 CARTON (71101-055-01) / 28.3 g in 1 TUBE Caring Mill Anti-Itch Cream Veridian Healthcare 2024-09-01
83324-0039-01 1 TUBE in 1 BOX (83324-039-01) / 28.3 g in 1 TUBE Anti-Itch Cream Chain Drug Marketing Association Inc. 2024-05-14
83650-0102-01 35.4 g in 1 TUBE (83650-102-01) Savvy Itch Stopping Savvy Care and Cosmetics 2023-09-22
Observed labelers: Kenvue Brands LLC (4) · Trifecta Pharmaceuticals USA, LLC. (3) · Amerisource Bergen (2) · CVS (2) · Strategic Sourcing Services LLC (2) · Veridian Healthcare (2) · +27 more — this is the FDA-listed mapping footprint, not sales, inventory, availability, or market share.

🗃️ Sources & Limits

Atlas generation902fddb9-e9c1-4004-bf4c-dba4d51037c7
openFDA export observedJul 14, 2026
RxNorm release07/06/2026
Methodology2026-07-full-catalog-v1
  • A shared RxCUI does not prove interchangeability. Products mapped to the same concept are not thereby equivalent or substitutable — equivalence is a separate, product-level determination.
  • Listing here does not establish approval or coverage. Appearing in this snapshot is a data observation, not an FDA approval status or a payer coverage decision.
  • Missing data never means zero. A silent dataset (no price, no billing code, no utilization) means no observation — not that the real-world value is zero.
  • Counts describe the mapping footprint. Product, package, and labeler counts are the FDA-listed mapping footprint in this snapshot — not sales, inventory, availability, or market share.
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Machine-readable JSON

Reference information about drug-concept identifiers and public regulatory data — not medical advice. Talk to your pharmacist or prescriber about your own medication.