foster and thrive anti itch cream Diphenhydramine Hydrochloride, Zinc Acetate 2 g/100g; .1 g/100g Cream
by Strategic Sourcing Services LLC · 1 TUBE in 1 CARTON (70677-1289-1) / 28 g in 1 TUBE
NDC 70677-1289-01
🏷️ FDA NDC (as labeled)
70677-1289-1
billing pads the package segment with a zero
OTC
On market
Non-controlled
🗂️ Data synced Jul 24, 2026 · sources: openFDA · FDA label (DailyMed) · FDA Orange & Purple Book · First Databank · CMS NADAC, ASP, Medicare & Medicaid · RxNorm
📋 All sources & update times →
🆔 Identity & classification
FDA NDC (as labeled)
70677-1289-1
Product NDC
70677-1289
11-digit billing NDC
70677128901
NCPDP billing unit
GM — per gram (weight)
RxCUI
1087026
UNII
TC2D6JAD40, FM5526K07A
Application #
M017
SPL Set ID
bb08293d-5db8-4cc8-9fe3-bd02061dbeb9
Established class (EPC)
Copper Absorption Inhibitor; Histamine-1 Receptor Antagonist
Mechanism of action
Histamine H1 Receptor Antagonists
Physiologic effect
Decreased Copper Ion Absorption
DEA schedule
Non-controlled
Marketing category
OTC MONOGRAPH DRUG
Marketing status
On market
FDA listing status
Listed (active directory)
Marketing start
2025-04-30
Route
TOPICAL
Dosage form
CREAM
Substance
DIPHENHYDRAMINE HYDROCHLORIDE; ZINC ACETATE
GPI-14
90209902083735
GCN Seq No
024972
GCN
67334
HICL code
009759
Ingredient (HICL)
Diphenhydramine Hcl/Zinc Acet
HIC1 code
L
Therapeutic class — broad (HIC1)
Skin/Subcutaneous Tissue
HIC2 code
L3
Therapeutic class — intermediate (HIC2)
Protectives
HIC3 code
L3P
Therapeutic class — specific (HIC3)
Antipruritics,Topical
AHFS code
84:08.00.00
AHFS class
Antipruritics And Local Anesthetics
FDB label name
FT ANTI-ITCH 2%-0.1% CREAM
FDB brand name
Anti-Itch
Legend status
O — Over-the-counter (OTC) drug or device
Why two NDCs?
The FDA registers this code as 70677-1289-1 — a 5-4-1 layout, and that's what's printed on the package and shown on DailyMed. For insurance claims, every NDC is standardized to a uniform 11-digit 5-4-2 format by adding a zero to the package segment → 70677-1289-01. Same drug, same package — only the format differs.
Where does this data come from?
Identifiers from the FDA openFDA NDC Directory and Structured Product Labeling; RxCUI from RxNorm (NLM); GPI from Medi-Span; GCN / HIC / AHFS / legend from First Databank.
🏷️ RxNorm drug class
This medicine belongs to the Histamine-1 Receptor Antagonist class.
Pharmacologic class
Histamine-1 Receptor Antagonist
Drug family (ATC)
Propionic acid derivatives, Antihistamines for topical use, Aminoalkyl ethers
How it works
Histamine H1 Receptor Antagonists
Where does this data come from?
Therapeutic classes from RxNorm RxClass (U.S. National Library of Medicine) — Established Pharmacologic Class (FDA), ATC drug family (WHO) and mechanism of action, matched by this product’s RxCUI.
🏭 Manufacturer & labeler
LabelerStrategic Sourcing Services LLC
FDA applicationM017 (OTC MONOGRAPH DRUG)
Labeler code70677
First marketedApr 2025
Product typeHuman Otc Drug
Portfolio316 products on file
The labeler markets the product; the application holder owns the FDA approval. They’re often the same company but can differ (e.g. a repackager or an authorized generic). A mailing address / phone appears here when the manufacturer includes it in the product’s FDA label (not all do).
Where does this data come from?
Labeler, application holder and registered establishment from the FDA openFDA NDC Directory and Drugs@FDA; address/contact from the product’s FDA label.
🩺 Clinical
Label name FT ANTI-ITCH 2%-0.1% CREAM Ingredient Diphenhydramine Hcl/Zinc Acet
📖 About the active ingredient: Diphenhydramine Hydrochloride; Zinc Acetate MedlinePlus · NLM
General information about the ingredient itself — the description of this specific product follows below.
Diphenhydramine is used to treat allergy and cold symptoms: sneezing runny nose red, itchy, watery eyes itching of the nose or throat Diphenhydramine is also used to treat insomnia (difficulty falling asleep or staying asleep) in adults, but should not be used to make a child sleepy. Diphenhydramine is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Diphenhydramine is also available in combination with other medications. This monograph only includes information about the use of diphenh...
Read the full MedlinePlus article ↗🧪 What is this product?
Foster and Thrive Anti Itch Cream is a topical cream containing diphenhydramine hydrochloride and zinc acetate. Diphenhydramine is an antihistamine commonly used in OTC products to help reduce itching and irritation. Zinc acetate is an astringent mineral salt typically included in skin-care formulations for its soothing properties. This is an over-the-counter monograph product, meaning it is marketed under FDA guidelines for its drug category rather than as an individually approved new drug application.
Patient education
Supplement & herbal interactions
1
Nutrient depletion considerations
Diphenhydramine Hydrochloride, Naproxen Sodium may be associated with lower levels of 1 nutrient — worth a chat with your pharmacist, not a cause for alarm.
An association is not a deficiency. Educational only — don't start or stop anything without professional guidance.
Where does this data come from?
Plain-language summary from MedlinePlus (U.S. National Library of Medicine); supplement & herbal interactions and nutrient depletion data from the Natural Medicines database; our full guide is HelloPharmacist editorial content.
💬 Questions about Diphenhydramine Hydrochloride, Zinc Acetate?
Ask a pharmacist →
Ask a licensed pharmacist directly — free, answered by our team.
🧪 Inactive Ingredients / Excipients
Inactive ingredients, also called excipients, are components of the drug product other than the active ingredient. They may include fillers, dyes, coatings, preservatives, flavors, or other formulation ingredients.
💡 Tap an ingredient (hover on desktop) to see what it is and why it’s used.
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UNII 936JST6JCN
Cetyl alcohol is a waxy, fatty substance derived from plant or animal sources. It acts as an emulsifier and thickener in medicines, helping blend oil and water components and giving products a smooth, creamy texture.
-
UNII H5RIZ3MPW4
A chemical preservative used to prevent bacterial and fungal growth in medicines. It helps extend shelf life and maintain product safety during storage and use.
-
UNII 94YQ11Y95F
A waxy substance made from glycol and fatty acids, used as an emulsifier and thickener to help blend oil and water ingredients together and give the medicine a smooth, uniform texture.
-
UNII A2I8C7HI9T
Methylparaben is a preservative derived from benzoic acid that prevents growth of bacteria, fungi, and mold in medicines. It extends the product's shelf life and maintains safety during storage.
-
UNII NBX892EA57
A synthetic compound made by combining polyethylene glycol with stearic acid. It acts as an emulsifier and surfactant to help mix oil and water-based ingredients, and improves how the medicine dissolves and spreads in the body.
-
UNII 6DC9Q167V3
Propylene glycol is a clear liquid derived from petroleum or vegetable sources. It acts as a solvent, humectant, and preservative in medicines, helping dissolve active ingredients and maintain product stability.
-
UNII Z8IX2SC1OH
Propylparaben is a chemical preservative used to prevent bacterial and fungal growth in medicines and personal care products. It helps extend shelf life and maintain product safety during storage.
-
UNII 059QF0KO0R
Water is a liquid solvent that dissolves and mixes ingredients together in liquid medicines, syrups, and injections. It helps distribute the active drug evenly throughout the product.
8 inactive ingredients listed in the exact product block matched to this NDC.
The official label also statescetyl alcohol, diazolidinyl urea, methylparaben, PEG-2 stearate, PEG-20 stearate, propylene glycol, propylparaben, purified water
Label-section wording can be broader than the structured product block and may mention additional formulation ingredients.
Where does this data come from?
Data sourced from official FDA Structured Product Labeling (SPL) via DailyMed —
ingredient classCode="IACT" elements from the exact product block matched by this NDC. Label-section narrative from DailyMed / the openFDA label index is shown separately when available.Inactive ingredient FAQ
Are inactive ingredients the same for every manufacturer?
No. Inactive ingredients can differ by manufacturer, dosage form, strength, and package / product version.
Why might an inactive ingredient be missing?
Some SPLs do not provide a complete structured inactive-ingredient list, and older or unusual labels may only include the information in narrative text.
Can inactive ingredients matter?
Yes. They can matter for allergies, intolerances, dyes, gluten / lactose concerns, preservatives, and formulation differences — but confirm with a pharmacist or the manufacturer when it’s clinically important.
💲 Pricing
A drug doesn't have one price. Each row is a different public payment system, and none is what you'd pay at the counter — that depends on your insurance. The ⓘ on each row explains what it measures.
| Price system | Per g | Per package |
|---|---|---|
| Retail pharmacies payNADAC · weekly | $0.057 | $1.60 / 28 g |
| Medicaid paysCMS SDUD · 12 mo | No recent Medicaid claims on file for this NDC — rare and low-volume NDCs are suppressed in the public data. | |
| Medicare drug plans payPart D · quarterly | No Part D plan price is available for this NDC in our data. | |
NADAC price history (per g) — tap or hover for the price & month
▼ Down 2% over the last 9 months.
Where does this data come from?
NADAC (National Average Drug Acquisition Cost) is the CMS weekly pharmacy-acquisition-cost survey — what pharmacies pay. ASP (Average Sales Price) is the CMS Medicare Part B drug-payment file, published quarterly. Medicaid pays is computed by us from CMS State Drug Utilization Data (total reimbursed ÷ units, trailing 12 months) — gross of rebates and inclusive of dispensing fees, so it reflects what Medicaid paid, not an acquisition cost. Medicare drug plans pay is the median negotiated point-of-sale unit cost across plans listing this NDC in the CMS quarterly Prescription Drug Plan pricing files, before rebates. The VA pays is the federal contract price (FSS, and the statutory Big 4 ceiling where listed) from the VA National Acquisition Center pharmaceutical price file. All are free public government data; each measures a different payer, so the figures are not directly comparable.
🔁 Therapeutic equivalents
| Product | Labeler | Pack | NADAC/unit | TE | Status | Price vs. this |
|---|---|---|---|---|---|---|
| good sense itch relief 2 g/100g; .1 g/100g 00113-0622-64 | L. | 1 tube | $0.057 | — | Availability likely | — |
| Banophen 2 g/100g; .1 g/100g 00904-5354-31 | Major | 1 tube | $0.057 | — | Availability likely | — |
| diphenhydramine hcl and zinc acetate 2 g/100g; .1 g/100g 45802-0358-03 | Padagis | 1 tube | $0.057 | — | Availability likely | — |
| GNP Extra Strength Anti-Itch Cream .1 g/100g; 2 g/100g 46122-0804-36 | Amerisource | 1 tube | $0.057 | — | Availability likely | — |
| leader anti itch 2 g/100g; .1 g/100g 70000-0388-01 | Cardinal | 1 tube | $0.057 | — | Availability likely | — |
| foster and thrive anti itch cream 2 g/100g; .1 g/100gthis 70677-1289-01 | Strategic | 1 tube | $0.057 | — | Availability likely | — |
| Anti-Itch 20 mg/g; 1 mg/g 24385-0210-03 | Amerisource | 1 tube | $0.130 | — | Discontinued | +127% |
| Diphenhydramine Hydrochloride and Zinc Acetate 20 mg/g; 1 mg/g 70677-1213-01 | STRATEGIC | 1 tube | $0.130 | — | FDA listed | +127% |
| Walgreens Anti Itch Cream 20 mg/g; 1 mg/g 00363-2315-28 | Walgreens | 1 tube | — | — | FDA listed | — |
| Dr. Sheffield Anti Itch Cream 20 mg/g; 1 mg/g 11527-0069-04 | Sheffield | 1 tube | — | — | FDA listed | — |
| Anti-itch 20 mg/g; 1 mg/g 11673-0895-28 | Target | 1 tube | — | — | FDA listed | — |
| Rite Aid Extra Strength Itch Stopping 1 mg/g; 20 mg/g 11822-6614-01 | Rite | 1 tube | — | — | FDA listed | — |
| signature care itch relief 2 g/100g; .1 g/100g 21130-0154-64 | Safeway | 1 tube | — | — | FDA listed | — |
| anti itch 2 g/100g; .1 g/100g 30142-0582-64 | Kroger | 1 tube | — | — | FDA listed | — |
| Shopko Anti-Itch 20 mg/g; 1 mg/g 37012-0089-02 | Shopko | 1 tube | — | — | FDA listed | — |
| itch relief 2 g/100g; .1 g/100g 37808-0622-64 | H | 1 tube | — | — | FDA listed | — |
| Anti-Itch Cream 1 mg/g; 20 mg/g 41226-0888-02 | Kroger | 1 tube | — | — | FDA listed | — |
| Anti Itch 2 g/100g; .1 g/100g 41250-0622-64 | Meijer | 1 tube | — | — | FDA listed | — |
| Equate Anti Itch 2 g/100g; .1 g/100g 49035-0622-64 | Wal-Mart | 1 tube | — | — | FDA listed | — |
| Diphenhydramine Hydrochloride and Zinc Acetate 20 mg/g; 1 mg/g 51672-2089-02 | Sun | 1 tube | — | — | FDA listed | — |
| CAREALL Anti-Itch 20 mg/g; 1 mg/g 51824-0088-01 | New | 35 g | — | — | FDA listed | — |
| Extra Strength Itch Stopping 20 mg/g; 1 mg/g 52000-0071-02 | Universal | 1 tube | — | — | FDA listed | — |
| Discount Drug Mart Extra Strength Itch Stopping 20 mg/g; 1 mg/g 53943-0258-01 | Discount | 1 tube | — | — | FDA listed | — |
| Family Wellness 2 g/100g; .1 g/100g 55621-0007-01 | Zhejiang | 1 tube | — | — | FDA listed | — |
| ItchZap 20 mg/g; 1 mg/g 57237-0352-28 | Rising | 1 tube | — | — | FDA listed | — |
| Itch Relief 2 g/100g; .1 g/100g 59779-0708-64 | CVS | 1 tube | — | — | FDA listed | — |
| Itch Relief Cream 2 g/100g; .1 g/100g 68016-0163-01 | Pharmacy | 1 tube | — | — | FDA listed | — |
| Anti-Itch Cream 2 g/100g; .1 g/100g 69396-0025-05 | Trifecta | 1 tube | — | — | FDA listed | — |
| Itch stopping Cream 2 g/100g; .1 g/100g 69396-0150-01 | Trifecta | 1 tube | — | — | FDA listed | — |
| itch relief 1 mg/g; 20 mg/g 69452-0449-37 | Bionpharma | 1 tube | — | — | FDA listed | — |
| Family Wellness 2 g/100g; .1 g/100g 69571-0005-02 | FRONT | 1 tube | — | — | FDA listed | — |
| CVS Extra Strength Itch Stopping 20 mg/g; 1 mg/g 69842-0321-28 | CVS | 1 tube | — | — | FDA listed | — |
| Benadryl Extra Strength Itch Stopping 20 mg/g; 1 mg/g 69968-0223-01 | Kenvue | 1 tube | — | — | FDA listed | — |
| TheraCare 2% Diphenhydramine Anti-Itch Cream 20 mg/g; 1 mg/g 71101-0014-01 | Veridian | 1 tube | — | — | FDA listed | — |
| Caring Mill Anti-Itch Cream 20 mg/g; 1 mg/g 71101-0055-01 | Veridian | 1 tube | — | — | FDA listed | — |
| Anti-Itch Cream 2 g/100g; .1 g/100g 83324-0039-01 | Chain | 1 tube | — | — | FDA listed | — |
| Savvy Itch Stopping 2 g/100g; .1 g/100g 83650-0102-01 | Savvy | 35.4 g | — | — | FDA listed | — |
| topcare anti itch 2 g/100g; .1 g/100g 36800-0622-64 | Topco | 1 tube | — | — | FDA listed | — |
| Itch Stopping 2 g/100g; .1 g/100g 42507-0622-64 | HyVee | 1 tube | — | — | FDA listed | — |
About this product: other versions of the same ingredient, strength and form are listed above, least expensive first, with FDA equivalence ratings where available.
Where does this data come from?
Equivalents are other NDCs of the same ingredient, form and route from the openFDA NDC Directory, ranked least-expensive-first by NADAC. Therapeutic-equivalence (AB) ratings come from the FDA Orange Book; biologics use the FDA Purple Book for biosimilar & interchangeable status.
⏳ Availability & generic status
🏛️
2025
On the market since
Apr 2025
📍
2026
Currently FDA-listed
1 year listed
🔒
·
No generic listed yet
brand only
ℹ️No FDA-approved generic found
We did not find an FDA-approved generic match for this exact strength, form and route.
Where does this data come from?
Patents and exclusivity from the FDA Orange Book (small-molecule drugs), refreshed from public FDA data. Generic launch timing is an estimate, not a guarantee.
🔬 Reported adverse events (FAERS)
Read carefully: FAERS reports are voluntary and unverified. Counts are not incidence, do not establish causation, are subject to reporting bias, and cannot be used to compare one drug to another. Shown for signal context only. Reports for Diphenhydramine Hydrochloride, Zinc Acetate — the ingredient across all brands.
Top reported reactions
Age at onset
Reporter sex
Male · 31%
Female · 69%
Serious outcomes
Reports over time (by year) — tap or hover for the count & year
Most recent year is provisional (FAERS lags ~3 months).
Where does this data come from?
Adverse-event reports from the FDA Adverse Event Reporting System (FAERS) via openFDA. FAERS reports are voluntary and unverified — counts are not incidence and don’t establish causation.
📦 Packaging — all sizes for this product
| Package NDC | Description | Marketing start | Status |
|---|---|---|---|
| 70677-1289-01 You're viewing this | 1 TUBE in 1 CARTON (70677-1289-1) / 28 g in 1 TUBE | 2025-04-30 | Active |
📄 FDA label — Drug Facts FDA SPL
The complete FDA label for this product — the official Drug Facts labeling, verbatim, section by section. Jump with a chip, search within the label, or expand everything.
🎯 Indications and Usage
⏱️ Dosage and Administration
⚠️ Warnings
📦 Storage and Handling
🧪 Active Ingredient
🧪 Inactive Ingredients
🎯 Purpose
🎯 Indications and Usage ▾
Uses • temporarily relieves pain and itching associated with: • insect bites • minor burns • sunburn • minor skin irritations • minor cuts • scrapes • rashes due to poison ivy, poison oak and poison sumac • dries the oozing and weeping of poison ivy, poison oak and poison sumac
⏱️ Dosage and Administration ▾
Directions • do not use more than directed • adults and children 2 years of age and older: apply to affected area no more than 3 to 4 times daily • children under 2 years of age: ask a doctor
⚠️ Warnings ▾
Warnings For external use only Do not use • on large areas of the body • with any other product containing diphenhydramine, even one taken by mouth Ask a doctor before use • on chicken pox • on measles When using this product • avoid contact with the eyes Stop use and ask a doctor if • condition worsens or does not improve within 7 days • symptoms persist for more than 7 days or clear up and occur again within a few days Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
📦 Storage and Handling ▾
Other information • store at 20°-25°C (68°-77°F)
🧪 Active Ingredient ▾
Active ingredient Diphenhydramine hydrochloride 2% Zinc acetate 0.1%
🧪 Inactive Ingredients ▾
Inactive ingredients cetyl alcohol, diazolidinyl urea, methylparaben, PEG-2 stearate, PEG-20 stearate, propylene glycol, propylparaben, purified water
🎯 Purpose ▾
Purpose Topical analgesic Skin protectant
No label section mentions that — try another word, or open the full label on DailyMed below.
Source: FDA Structured Product Labeling, mirrored from DailyMed / openFDA.
Prefer the government’s original formatting? View this label on DailyMed ↗
For educational and professional reference only — not medical advice. Pricing reflects published
NADAC and CMS ASP (free public data) and may differ from your acquisition cost; always verify before billing or dispensing.