Herb & supplement monograph

Blueberry Drug Interactions, Uses, Effectiveness, Safety & More

Medically reviewed by ·Updated July 2026
What is this page for?

First and foremost: how Blueberry interacts with medications. The heart of this page is the interaction list — every drug Blueberry is known to interact with, and how serious each one is.

But these pages have grown well beyond that into a full monograph — what Blueberry is, what people use it for and how strong the evidence is, its safety and side effects, and answers to the questions we’re asked most — written and reviewed by the clinical staff at HelloPharmacist. It’s educational information from our licensed clinical databases, not medical advice, and we don’t sell or endorse products. Our editorial policy

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Blueberry Drug Interactions: The Bottom Line

From the HelloPharmacist Editorial Team · Updated July 2026

Based on the available evidence, the overall risk of a clinically significant Blueberry drug interaction appears low for most people. None of the listed interactions are rated major or even moderate, and every one is graded minor with weak or disproven documentation.

Interactions deserving the most attention

Honestly, no interaction on this profile stands out as well established in people. The one worth a mention is with diabetes medications, since animal and lab research suggests blueberry or blueberry leaf extracts might lower blood sugar, which could in theory add to the effect of these drugs. This has not been confirmed in humans, but people whose blood sugar is closely managed may want to be aware of it. Concerns raised for buspirone and flurbiprofen were tested in humans and did not pan out.

What the rest of the list means

A long list of interacting medications can look worrying, but here it mostly reflects theory rather than proven harm. Lab studies suggested blueberry juice might slow enzymes the body uses to clear certain medications, yet when this was tested in people, blood levels of those drugs did not change in a meaningful way. That pattern is reassuring for the rest of the list, which rests on similar theoretical reasoning.

Check your medications against Blueberry

Based on HelloPharmacist’s Blueberry interaction data and reviewed under our editorial standards.

Interaction report

Drugs that interact with Blueberry

88 medications have a known interaction with Blueberry, graded by severity. Select any drug for the full evidence-based detail.

2,830 drugs
AcarboseGlucobay, Prandase, Precose
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Acarbose interaction Acarbose drug page: uses, dosage & side effects
AcetohexamideDymelor
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Acetohexamide interaction
AlbiglutideTanzeum
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Albiglutide interaction
AlogliptinNesina
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Alogliptin interaction Alogliptin drug page: uses, dosage & side effects
Alogliptin, MetforminKazano
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Alogliptin, Metformin interaction
Alogliptin, PioglitazoneOseni
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Alogliptin, Pioglitazone interaction
Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interaction
BuspironeBuSpar
Minor Buspirone (buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.

Read the full Blueberry + Buspirone interaction Buspirone drug page: uses, dosage & side effects
CanagliflozinInvokana
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Canagliflozin interaction Canagliflozin drug page: uses, dosage & side effects
Canagliflozin, MetforminInvokamet
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Canagliflozin, Metformin interaction
Canagliflozin, Metformin HydrochlorideInvokamet XR
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Canagliflozin, Metformin Hydrochloride interaction
ChlorpropamideChlorpropam, Diabinese
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Chlorpropamide interaction
DapagliflozinFarxiga
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Dapagliflozin interaction Dapagliflozin drug page: uses, dosage & side effects
Dapagliflozin Propanediol, MetforminXigduo XR
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Dapagliflozin Propanediol, Metformin interaction
Dapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interaction
Dapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interaction
Dasiglucagon HydrochlorideZegalogue
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Dasiglucagon Hydrochloride interaction Dasiglucagon Hydrochloride drug page: uses, dosage & side effects
DulaglutideTrulicity
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Dulaglutide interaction Dulaglutide drug page: uses, dosage & side effects
EmpagliflozinJardiance
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Empagliflozin interaction Empagliflozin drug page: uses, dosage & side effects
Empagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Empagliflozin, Linagliptin, Metformin Hydrochloride interaction
Empagliflozin, MetforminSynjardy
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Empagliflozin, Metformin interaction
Empagliflozin, Metformin HydrochlorideSynjardy XR
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Empagliflozin, Metformin Hydrochloride interaction
ErtugliflozinSteglatro
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Ertugliflozin interaction Ertugliflozin drug page: uses, dosage & side effects
Ertugliflozin, Metformin HydrochlorideSegluromet
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Ertugliflozin, Metformin Hydrochloride interaction
ExenatideBydureon, Byetta
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Exenatide interaction Exenatide drug page: uses, dosage & side effects
Exenatide SyntheticBydureon BCISE
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Exenatide Synthetic interaction Exenatide Synthetic drug page: uses, dosage & side effects
FlurbiprofenAnsaid, Flurbiprofen, Flurprofen, Froben, Froben SR, Ocufen
Minor Flurbiprofen (ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.

Read the full Blueberry + Flurbiprofen interaction Flurbiprofen drug page: uses, dosage & side effects
GliclazideDiamicron
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Gliclazide interaction
GlimepirideAmaryl
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Glimepiride interaction Glimepiride drug page: uses, dosage & side effects
GlipizideGlucotrol, Glucotrol XL
Minor Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.

Read the full Blueberry + Glipizide interaction Glipizide drug page: uses, dosage & side effects
Read The List Like a Pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each drug listed above links to the full report for that exact Blueberry combination — clinical detail, likelihood, evidence level, and citations.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
The big picture

The kinds of drugs Blueberry affects

Every type of medication (drug category) Blueberry is known to interact with. Open any category for the detail — or search your exact drug in the checker above.

All 3 drug categories Blueberry interacts with
Antidiabetes DrugsBuspirone (buspar)Flurbiprofen (ansaid, Others)
Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
Monograph

Blueberry: Uses, Safety & Side Effects

Medically reviewed by · Reviewed July 2026 ·
The bottom line

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most people. Concentrated supplements are marketed for heart, brain, and blood sugar health, but the evidence is mostly early and not strong enough to promise specific benefits. Enjoy blueberries as food, and talk to your pharmacist before using high-dose extracts.

Scientific name
Vaccinium spp.
Family
Ericaceae
Part used
Fruit (berries); sometimes leaves
Common forms
Fresh or frozen fruit, juice, dried berries, powder, extract capsules, tea
People commonly use it for
  • Antioxidant support
  • Heart health
  • Brain and memory health
  • Blood sugar support
  • Eye health
  • Urinary health

Popular and traditional uses — not proof it works. See “Uses & effectiveness” below for the evidence.

Safety at a glance
OverallLikely safe

Blueberries are widely eaten as food and are generally safe for most people.

PregnancyLikely Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of blueberry for medicinal...

Read the full pregnancy detail
BreastfeedingLikely Safe

When used orally in amounts commonly found in foods. There is insufficient reliable information available about the safety of blueberry for medicinal...

Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center). Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Jump to a section

Overview

Blueberries are small, sweet, blue-purple berries that grow on shrubs in the Vaccinium family. They are closely related to cranberries and bilberries. The two most common types are highbush blueberries (often grown commercially) and lowbush or "wild" blueberries. Blueberries grow widely in North America and other temperate regions.

People eat blueberries fresh, frozen, dried, or as juice, and they are popular as a healthy snack. Beyond food, blueberries are sold as supplements such as powders, extract capsules, and concentrated juices, which are marketed for heart health, brain health, and general antioxidant support.

How it works

Blueberries are rich in anthocyanins and other polyphenols. In laboratory and animal studies, these compounds act as antioxidants, meaning they may help reduce a type of cell stress called oxidative stress and may calm inflammation.

Scientists also think blueberry compounds may support the lining of blood vessels and may affect how the body handles sugar. It is important to know that much of this work comes from test-tube and animal research, and effects seen in a lab do not always translate into clear benefits for people.

Effectiveness

Does Blueberry work?

Here’s what the research actually shows for each use — graded by Natural Medicines and reviewed by .

Evidence overview · 19 uses evaluated
1 Leans ineffective 18 Insufficient evidence
How to read these evidence grades

Natural Medicines’ 7-point scale. We show each rating’s label word-for-word.

1EffectiveStrong, consistent evidence it works.
2Likely EffectiveGood evidence, though not yet conclusive.
3Possibly EffectiveSome evidence suggests a benefit.
4Possibly IneffectiveSome evidence it may not help.
5Likely IneffectiveFairly strong evidence it doesn’t help.
6IneffectiveStrong evidence it doesn’t work.
7Insufficient Reliable Evidence to RateToo little research to say either way.
Possibly Ineffective Hypertension
Rating & evidence shown verbatim from Natural Medicines

Most clinical research suggests that consuming freeze-dried blueberries or blueberry powder does not lower blood pressure in patients with hypertension, prehypertension, or other risk factors for cardiovascular disease.

Also studied for 18 conditions — evidence insufficient to rate
Insufficient Reliable Evidence To Rate Age-related cognitive decline
Rating & evidence shown verbatim from Natural Medicines

Small clinical studies suggest that oral blueberry products may slightly improve some measures of cognitive function in older adults with age-related cognitive decline.

Insufficient Reliable Evidence To Rate Aging
Rating & evidence shown verbatim from Natural Medicines

It is unclear if consuming blueberry can improve functional mobility in adults 60 years of age and older.

Insufficient Reliable Evidence To Rate Anxiety
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral blueberry can improve symptoms of anxiety.

Insufficient Reliable Evidence To Rate Athletic performance
Rating & evidence shown verbatim from Natural Medicines

Small clinical studies suggest that oral freeze-dried blueberry powder may not reduce exertion or improve long-distance running performance in trained runners.

Insufficient Reliable Evidence To Rate Cancer
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral blueberry for preventing cancer, there is insufficient reliable information about the clinical effects of blueberry for this purpose.

Insufficient Reliable Evidence To Rate Cardiovascular disease (CVD)
Rating & evidence shown verbatim from Natural Medicines

Small clinical studies suggest that oral blueberry supplementation might modestly improve body weight and triglyceride levels, but not body mass index (BMI), glycemic control, or cholesterol levels, in patients at risk for CVD.

Insufficient Reliable Evidence To Rate Cataracts
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral blueberry for preventing cataracts, there is insufficient reliable information about the clinical effects of blueberry for this purpose.

Insufficient Reliable Evidence To Rate Cognitive function
Rating & evidence shown verbatim from Natural Medicines

Small clinical studies suggest that oral blueberry products may improve some, but not most, measures of cognitive function in children and adults.

Insufficient Reliable Evidence To Rate Depression
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral blueberry extract or freeze-dried powder is beneficial in patients with depression.

Insufficient Reliable Evidence To Rate Diabetes
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral freeze-dried blueberry powder is beneficial in patients with diabetes.

Insufficient Reliable Evidence To Rate Hyperlipidemia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral blueberry is beneficial in patients with hyperlipidemia.

Insufficient Reliable Evidence To Rate Hypertriglyceridemia
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral blueberry leaf extract is beneficial in patients with hypertriglyceridemia.

Insufficient Reliable Evidence To Rate Juvenile idiopathic arthritis (JIA)
Rating & evidence shown verbatim from Natural Medicines

It is unclear if oral blueberry juice is beneficial in children with JIA.

Insufficient Reliable Evidence To Rate Metabolic syndrome
Rating & evidence shown verbatim from Natural Medicines

Small clinical studies in patients with metabolic syndrome, along with an analysis of studies in patients at risk for metabolic syndrome, suggest that oral freeze-dried blueberries do not improve body weight or glycemic control, but may slightly lower blood pressure and cholesterol levels.

Insufficient Reliable Evidence To Rate Muscle strength
Rating & evidence shown verbatim from Natural Medicines

Oral blueberry has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Night vision
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral blueberry for improving night vision, there is insufficient reliable information about the clinical effects of blueberry for this purpose.

Insufficient Reliable Evidence To Rate Obesity
Rating & evidence shown verbatim from Natural Medicines

Oral blueberry has only been evaluated in combination with other ingredients; its effect when used alone is unclear.

Insufficient Reliable Evidence To Rate Urinary tract infections (UTIs)
Rating & evidence shown verbatim from Natural Medicines

Although there has been interest in using oral blueberry for preventing UTIs, there is insufficient reliable information about the clinical effects of blueberry for this purpose.

Source & disclaimer. Effectiveness ratings and evidence summaries are provided by Natural Medicines (Therapeutic Research Center) and shown as licensed. Where Natural Medicines hasn’t rated a use, HelloPharmacist’s pharmacists may add their own reviewed rating and evidence (each such entry is labeled). This is educational information, not medical advice — talk with your pharmacist or doctor before starting, stopping, or changing a supplement.

Safety & precautions

For most people, eating blueberries as food is very safe and healthy. Concentrated supplements and extracts are less studied, so it is harder to be sure about their safety at high doses.

People with allergies to blueberries or related berries should avoid them. If you have a medical condition or take medicine that affects blood sugar or blood clotting, talk with your pharmacist or doctor before using blueberry supplements.

Pregnancy and breastfeeding: Blueberries eaten as a normal part of the diet are considered fine. However, the safety of concentrated blueberry extracts or high-dose supplements during pregnancy or breastfeeding has not been well studied, so it is best to avoid these products or use them only with medical advice.

Side effects

Blueberries as food rarely cause side effects. Eating large amounts may cause mild digestive upset, such as gas, bloating, or loose stools, mostly because of their fiber content.

Allergic reactions are uncommon but possible. Concentrated supplements have not been studied as thoroughly, so their long-term side effects are not fully known. Stop use and seek medical care if you have signs of an allergic reaction, such as rash, swelling, or trouble breathing.

Blueberry: Reported Adverse Effects

Documented safety reports on Blueberry from the evidence-graded Natural Medicines (TRC Healthcare) database, shown word-for-word from the licensed record.

Orally, blueberry is generally well tolerated.

Most Common Adverse Effects:

Orally: Constipation, diarrhea, nausea, and vomiting with freeze-dried blueberries.

Reports by condition
Constipation Gastrointestinal

Orally, freeze-dried blueberries may cause constipation, diarrhea, nausea, and vomiting. In one clinical trial, 26% of patients taking freeze-dried blueberries 50 grams daily dropped out in the first week of the study due to gastrointestinal complaints.

  1. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

Adverse-effects data: Natural Medicines, Therapeutic Research Center

Dosing

There is no official standardized dose of blueberry for any health condition. As a food, a typical serving is around a half to one cup of fresh berries, which most people can enjoy daily.

For supplements such as extract capsules, powders, or juices, the right amount varies by product, and a proven medical dose has not been established. Follow the directions on the product label and check with your pharmacist or doctor before starting a concentrated supplement, especially if you have a health condition or take other medicines.

Pregnancy & Breastfeeding
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.

© 2026 Therapeutic Research Center

Pregnancy & lactation ratings: Natural Medicines, Therapeutic Research Center

References & further reading

The 7 references that drive our Blueberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed
Keep reading

This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Brand directory

Brands that make products with Blueberry

787 brands in our database make a supplement containing Blueberry.

Product directory

Supplement products with Blueberry

5,565 products in our database contain Blueberry. Open any to see its full ingredient list and every drug interaction we check.

10-Day Acai Berry Easy-Cleanse by Applied Nutrition Tablet Or Pill 40 Tablet(s) View ingredients & interactions 100% Berries + Whey Berry Flavor by BioChem Powder 20.3 Oz(s) · 1.3 lbs · 575.4 Gram(s) View ingredients & interactions 100% Berries + Whey Berry Flavor by BioChem Powder 10.1 Oz(s) · 287.7 Gram(s) View ingredients & interactions 100% Fermented Organic Greens Organic Chocolate by Natural Factors Whole Earth & Sea Powder 7.7 Ounce(s) · 219 Gram(s) View ingredients & interactions 100% Fermented Organic Greens Unflavored by Natural Factors Whole Earth & Sea Powder 6.9 Ounce(s) · 195 Gram(s) View ingredients & interactions 100% Vegan Complete MultiVitamin by Purely Inspired Tablet Or Pill 90 Vegan Tablet(s) View ingredients & interactions 100% Whole Food Prenatal by Whole Body Research Capsule 120 Vegetarian Capsule(s) View ingredients & interactions 14-Day Acai Berry Cleanse by Applied Nutrition Tablet Or Pill 56 Tablet(s) View ingredients & interactions 14-Day Acai Berry Cleanse by Applied Nutrition Tablet Or Pill 56 Tablet(s) View ingredients & interactions 2-Day Diet Detox Natural Berry Flavor by SuperJuice Liquid 473 mL View ingredients & interactions 24K by Reliv Liquid 30 fl. Oz. · 1 pt. · 14 fl. Oz. · 887 mL View ingredients & interactions 24K by Reliv Powder 10.6 Ounce(s) View ingredients & interactions 24K Mixed Berry Flavor by Reliv Powder 10.6 Ounce(s) View ingredients & interactions 37 Strawberries by Purity Products Capsule 30 Capsule(s) View ingredients & interactions 4Life Transfer Factor RioVida by 4Life Liquid 2 Bottle(s) View ingredients & interactions 4Life Transfer Factor Riovida by 4Life Liquid 16.9 fl. Oz. · 500 mL View ingredients & interactions 5-Day Acai Berry Cleanse by Applied Nutrition Tablet Or Pill 20 Tablet(s) View ingredients & interactions 5-Day Liquid Cleanse & Flush by Applied Nutrition Liquid 10 Liquid Tube · 100 mL · 3.35 fl. Oz. View ingredients & interactions 5% Pump by Rich Piana 5% Nutrition Code Red Series Capsule 100 Capsule(s) View ingredients & interactions 50 & Wiser Men by Garden of Life Vitamin Code Capsule 240 Vegetarian Capsule(s) View ingredients & interactions 50 & Wiser Men by Garden of Life Vitamin Code Capsule 240 Vegetarian Capsule(s) View ingredients & interactions 50 & Wiser Men by Garden of Life Vitamin Code Capsule 240 Vegetarian Capsule(s) View ingredients & interactions 50 & Wiser Men by Garden of Life Vitamin Code Capsule 120 Vegetarian Capsule(s) View ingredients & interactions 50 & Wiser Men by Garden of Life Vitamin Code Capsule 120 Vegetarian Capsule(s) View ingredients & interactions
Pharmacist Counseling Corner

Blueberry: Common Questions

What is Blueberry used for, and does it work?
People use Blueberry for a range of reasons, but according to the Natural Medicines database the current clinical evidence is insufficient to confirm it works for the specific conditions it has been studied for. See the graded list on this page, and talk to your pharmacist or doctor before relying on it for any condition.
Does Blueberry interact with prescription medications?
Yes. We list 88 medications with a known interaction with Blueberry. Use the checker above to see how Blueberry interacts with a specific drug.
How are Blueberry interactions rated?
Each interaction is graded major, moderate, or minor based on how clinically significant it is and the strength of the evidence behind it. Major interactions are the most serious and are best avoided, or used only under close professional supervision.
Is it safe to take Blueberry with my medications?
It depends on the specific medication. Some combinations are fine, while others call for monitoring, timing changes, or should be avoided. Check your exact drug above and confirm with your pharmacist or doctor before starting, stopping, or changing anything.
Where does this Blueberry interaction information come from?
Our interaction data is built on the Natural Medicines database — an evidence-graded reference for vitamins, herbs, and supplements — and is reviewed by licensed HelloPharmacist pharmacists, who may add clinical context.
Are blueberries good for you?
Yes. Blueberries are a nutritious, low-calorie fruit rich in fiber, vitamin C, and antioxidant compounds, and they fit well into a healthy, balanced diet.
Do Blueberry supplements work better than eating the fruit?
There is no strong evidence that supplements are better than fresh or frozen blueberries. For most people, eating the whole fruit is a simple, well-studied way to get the benefits.
Can I eat blueberries while pregnant or breastfeeding?
Blueberries eaten as a normal food are generally considered fine. However, concentrated Blueberry supplements have not been well studied during pregnancy or breastfeeding, so it is safest to avoid those unless your doctor approves.
Can eating too many blueberries cause problems?
Eating a lot at once may cause mild gas, bloating, or loose stools because of the fiber. In normal serving sizes, blueberries rarely cause problems for most people.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Products that contain Blueberry

A rotating sample of real supplements in our database that list Blueberry — open any to see its full ingredients and every drug interaction we check.

See all 5,565 products with Blueberry →
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