Amikacin

Name: Amikacin Drug Interactions
Creator: Dr. Brian Staiger, PharmD, BCPS

19 interactions

Medically reviewed by Dr. Brian Staiger, PharmD, BCPS · Updated Jul 11, 2026 · Editorial policy · Data sources

Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →

Most serious with: Aspirin Aspirin Rectal Cefepime Injection Cidofovir Injection Colistimethate Injection Emtricitabine

8 Major 5 Moderate 6 Minor

All (19) Major (8) Moderate (5) Minor (6)

Major

Amikacin Aspirin Acuprin® Increased aspirin exposure and an increased risk of nephrotoxicity Details Amikacin Aspirin Rectal Aspirin Increased aspirin exposure and an increased risk of nephrotoxicity Details Amikacin Cefepime Injection Maxipime® An increased risk of nephrotoxicity and an increased risk of ototoxicity Details Amikacin Cidofovir Injection Vistide® Nephrotoxicity Details Amikacin Colistimethate Injection Coly-Mycin M® Respiratory depression Details Amikacin Emtricitabine Emtriva Increased emtricitabine exposure and an increased risk of emtricitabine-related adverse effects Details Amikacin Foscarnet Injection Foscavir Nephrotoxicity Details Amikacin Furosemide Injection Disal Increased amikacin exposure and an increased risk of ototoxicity and/or nephrotoxicity Details

Check another drug

Still have questions about this combination?

Every question gets a real answer from a licensed pharmacist — free, and usually within a day.

Ask the pharmacist

Educational information only, not medical advice. Always confirm interactions with your pharmacist or prescriber before making any change to your medications.