Mitapivat
295 interactions 80 cited referencesMitapivat is used to treat hemolytic anemia (a blood disorder that occurs when red blood cells are destroyed faster than they can be made in the body) in people with pyruvate kinase deficiency. Mitapivat is in a class of medications called pyruvate kinase activators. It works by increasing pyruvate kinase available to… Read the full Mitapivat drug information page →
Sources: FDA prescribing information (Structured Product Labeling), the published literature cited in each entry, DDInter 2.0 (a major open-access drug-interaction database), and legacy DrugBank interaction data distributed by the NIH's RxNav service (decommissioned in 2024) — analyzed and reviewed by our pharmacist team. How we build this library →
Moderate
Mitapivat Clobazam Onfi Reduced CYP2C19 substrate exposure Details Mitapivat Dasabuvir Reduced CYP2C8 substrate exposure Details Mitapivat Glyburide DiaBeta® Reduced CYP2C9 substrate exposure Details Mitapivat Kratom Increased CYP3A substrate exposure Details Mitapivat Lumefantrine Reduced artemether/lumefantrine exposure, reduced efficacy of artemether/lumefantrine and loss of antimalarial efficacy Details Mitapivat Mephenytoin Reduced CYP2C19 substrate exposure Details Mitapivat Pantoprazole Protonix Reduced CYP2C19 substrate exposure Details Mitapivat Phenprocoumon Reduced CYP2C9 substrate exposure Details Mitapivat Piroxicam Feldene Reduced CYP2C9 substrate exposure Details Mitapivat Proguanil Reduced CYP2C19 substrate exposure Details Mitapivat Repaglinide Prandin® Reduced CYP2C8 substrate exposure Details Mitapivat Selexipag Uptravi Reduced CYP2C8 substrate exposure Details Mitapivat Siponimod Mayzent Reduced CYP2C9 substrate exposure Details Mitapivat Tolbutamide Orinase® Reduced CYP2C9 substrate exposure Details Mitapivat Trimipramine Reduced CYP2C19 substrate exposure DetailsNo interactions on this page match that filter — try the next page or clear the filter.
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