Drug & supplement interaction

Ascorbigen + Azilsartan, Chlorthalidone

Azilsartan, Chlorthalidone brand name: Edarbyclor.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Ascorbigen and Azilsartan, Chlorthalidone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Ascorbigen and Azilsartan, Chlorthalidone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Azilsartan, Chlorthalidone and Ascorbigen in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Ascorbigen at all — not against Azilsartan, Chlorthalidone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Ascorbigen safety at a glance

Ascorbigen overall Not established There is very little human safety data on ascorbigen as a supplement.
Pregnancy Avoid Safety has not been studied in pregnancy, so it is best to avoid it.
Breastfeeding Avoid No safety data exist for breastfeeding, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Azilsartan, Chlorthalidone and Ascorbigen? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Ascorbigen Itself Has Been Linked To

This is not an interaction — nothing below involves Azilsartan, Chlorthalidone. It is the side-effect record for Ascorbigen on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Ascorbigen, this list is the first place to look.

  • Bloating or gas Additional detail

    “Orally, when used in combination with broccoli powder, ascorbigen has been reported to cause flatulence, abdominal distension, and unpleasant after taste. It is unclear if these effects are due to ascorbigen, broccoli powder, or the combination.”

    Ascorbigen · Natural Medicines adverse-effect record, reported in flatulence.

    1 source cited
    1. 15460. Bramwell B, Ferguson S, Scarlett N, Macintosh A. The use of ascorbigen in the treatment of fibromyalgia patients: a preliminary trial. Altern Med Rev 2000;5:455-62.

Everything above comes from the Natural Medicines adverse-effect record for Ascorbigen — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Azilsartan, Chlorthalidone’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Azilsartan, Chlorthalidone column appears here.

Everything else you take

See Every Supplement That Interacts With Azilsartan, Chlorthalidone

This page covers Ascorbigen only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Azilsartan, Chlorthalidone page lists 266 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Dolomite (major) and Lithium (major).

By severity: 8 major · 222 moderate · 36 minor.

From our pharmacist’s overview on the Azilsartan, Chlorthalidone page

“Edarbyclor pairs azilsartan with chlorthalidone to lower blood pressure two ways, and that is exactly why this list warrants genuine care. Most entries either push blood pressure down further than intended or pile onto the diuretic's fluid and potassium effects.”

Reviewed by 2 · Jul 18, 2026

Open the Azilsartan, Chlorthalidone interaction page

One more smart check

Taking Ascorbigen as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2 real supplement products containing Ascorbigen, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Ascorbigen. Even though Ascorbigen itself has no known interaction with Azilsartan, Chlorthalidone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Ascorbigen and Azilsartan, Chlorthalidone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Ascorbigen
Top half

#638 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Azilsartan, Chlorthalidone
Top 25%

#615 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ascorbigen reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Ascorbigen and Azilsartan, Chlorthalidone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Ascorbigen

What is Ascorbigen?

Ascorbigen
  • Antioxidant support
  • Immune support
  • Fibromyalgia symptoms
  • General wellness
  • Detoxification support

Ascorbigen is a natural compound formed when indole-3-carbinol (from cruciferous vegetables) combines with vitamin C, and it is mainly studied in the lab and in early research. There is not enough good human evidence to confirm it helps any specific health condition, and its safety as a supplement is not well established. Talk with your pharmacist or doctor before taking it.

Derived from cruciferous vegetables (such as cabbage, broccoli, Brussels sprouts) · Capsules, tablets, found naturally in cruciferous vegetables and some combination supplements

An interaction check asks whether these two react with each other — it does not ask whether Ascorbigen is a good idea for someone in your situation. Here is what our Ascorbigen record says about it on its own.

Ascorbigen: dosing

There is no established standard dose for ascorbigen. It has not been studied enough in humans to know a safe and effective amount.If you choose to use a product that contains ascorbigen, follow the directions on the label and do not exceed the recommended amount.

From our Ascorbigen monograph — the full record covers uses, side effects and every documented interaction.

Read the full Ascorbigen monograph & all interactions
Keep checking

Other Drugs & Ascorbigen

Browse every other medication we’ve checked against Ascorbigen — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Ascorbigen against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Ascorbigen list.

See the full Ascorbigen interactions page
See every supplement checked against Azilsartan, Chlorthalidone, ranked by severity
Evidence & sources

Ascorbigen References

The 1 references that drive our Ascorbigen monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Bramwell B, Ferguson S, Scarlett N, Macintosh A. The use of ascorbigen in the treatment of fibromyalgia patients: a preliminary trial. Altern Med Rev 2000;5:455-62.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Ascorbigen and Azilsartan, Chlorthalidone Together: Common Questions

Is it safe to take Ascorbigen with Azilsartan, Chlorthalidone?
We do not list a known interaction between Ascorbigen and Azilsartan, Chlorthalidone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Azilsartan, Chlorthalidone interact with any supplements?
Yes. Azilsartan, Chlorthalidone has documented interactions with 266 supplements in our database — Ascorbigen is not one of them. The Azilsartan, Chlorthalidone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Ascorbigen monograph Uses, safety profile, and every drug interaction in one place Azilsartan, Chlorthalidone supplement interactions Every supplement checked against Azilsartan, Chlorthalidone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Azilsartan, Chlorthalidone and Ascorbigen?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.