Autumn Crocus + Rabeprazole
Rabeprazole brand name: Pariet.
We found no known interaction between Autumn Crocus and Rabeprazole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Autumn Crocus and Rabeprazole
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Rabeprazole and Autumn Crocus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Autumn Crocus safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Rabeprazole
Interactions in our licensed database are recorded against drug classes, not just single drug names. Rabeprazole is filed under 9 classifications — including proton pump inhibitors (ppis), cytochrome p450 2c19 (cyp2c19) inhibitors, cytochrome p450 1a2 (cyp1a2) inducers. Autumn Crocus has documented interactions with 1 drug class — the most serious being colchicine (major) — and none of Rabeprazole’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Autumn Crocus Does Interact With Other Medications
Autumn Crocus has 2 major, known drug interactions in our database — Rabeprazole isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Autumn Crocus
We haven’t checked that one against Autumn Crocus yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Autumn Crocus. Pick one to open its full report.
Autumn Crocus in Pregnancy & Breastfeeding
When used orally. Autumn crocus is a potential mutagen and is associated with significant and potentially fatal adverse effects; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Questions About Autumn Crocus or Rabeprazole
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Autumn Crocus or Rabeprazole, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Which Acid-Reducing Drugs Are Safe With Plavix? ›
- Can You Take Adderall With Proton Pump Inhibitors? ›
- Does Omeprazole Cause Hair Loss? ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Rabeprazole
This page covers Autumn Crocus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rabeprazole page lists 172 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 119 moderate · 50 minor.
From our pharmacist’s overview on the Rabeprazole page
“Rabeprazole (Pariet) quiets stomach acid for reflux and ulcers, but its supplement list deserves genuine care, with three serious entries to understand before anything else. Most items matter because they change how the liver breaks rabeprazole down, so its level can drift up or down.”
Reviewed by 2 · Jul 18, 2026
Taking Autumn Crocus as Part of a Dietary Supplement Product? Check It for Interactions
We hold 1 real supplement products containing Autumn Crocus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Autumn Crocus. Even though Autumn Crocus itself has no known interaction with Rabeprazole, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Autumn Crocus and Rabeprazole Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#1,311 of 1,452 supplements looked up here in the last 7 days
#1,275 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Autumn Crocus reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Autumn Crocus and Rabeprazole records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Autumn Crocus
What is Autumn Crocus?
- Gout
- Familial Mediterranean fever
- Joint pain and inflammation
- Rheumatoid arthritis (traditional use)
Autumn Crocus is a highly poisonous plant that contains colchicine, a compound that has real medical value but is dangerous in its raw form. You should never eat the plant or take homemade preparations from it. If you need colchicine for gout or familial Mediterranean fever, use the standardized, FDA-approved prescription product under a doctor's supervision.
Colchicum autumnale · Colchicaceae · Corm (bulb-like underground stem), seeds, and flowers · Rarely used as a raw plant or crude extract; the purified active compound (colchicine) is available only as an FDA-approved prescription medicine
An interaction check asks whether these two react with each other — it does not ask whether Autumn Crocus is a good idea for someone in your situation. Here is what our Autumn Crocus record says about it on its own.
Autumn Crocus: dosing
There is no safe established dose of the Autumn Crocus plant as a supplement, and it should not be taken in any homemade form. The colchicine content of the plant cannot be reliably measured, so even small amounts can cause serious harm.The only appropriate way to use colchicine is through an FDA-approved prescription product, which has a precise, controlled dose set by your healthcare provider.
From our Autumn Crocus monograph — the full record covers uses, side effects and every documented interaction.
About Rabeprazole
What Is Rabeprazole Used For?
Brand name: Pariet
Rabeprazole delayed-release tablets treat a range of acid-related conditions in adults, including healing and maintenance of erosive or ulcerative GERD (gastroesophageal reflux disease), symptomatic GERD, duodenal ulcers, and pathological hypersecretory conditions such as Zollinger-Ellison syndrome. They are also used alongside antibiotics (amoxicillin and clarithromycin) to eradicate H. pylori bacteria and reduce the risk of duodenal ulcer coming back.
In adolescents 12 years and older, rabeprazole delayed-release tablets are approved for short-term treatment of symptomatic GERD. Both AcipHex and Rabeprazole Sodium delayed-release tablets share this indication set for adults and adolescents 12 and older.
Other Drugs & Autumn Crocus
Browse every other medication we’ve checked against Autumn Crocus — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
2 interactions
No interaction 2,827 drugs checked — show the list
We also checked Autumn Crocus against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Losartan Potassium ›
- Testosterone ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Citalopram ›
- Buspirone ›
Showing the 60 most looked-up of 2,827 medications checked with no known interaction — see the full Autumn Crocus list.
Autumn Crocus References
The 9 references that drive our Autumn Crocus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brvar, M., Kozelj, G., Mozina, M., and Bunc, M. Acute poisoning with autumn crocus (Colchicum autumnale L.). Wien.Klin Wochenschr. 3-31-2004;116(5-6):205-208. PubMed
- Kritikos A, Spertini O. Reversible granulocyte abnormalities after accidental ingestion of Colchicum autumnale. Blood 2017;130(1):95. doi: 10.1182/blood-2017-02-766410. PubMed
- Nagesh KR, Menezes RG, Rastogi P, et al. Suicidal plant poisoning with Colchicum autumnale. J Forensic Leg Med 2011;18(6):285-7. doi: 10.1016/j.jflm.2011.04.008. PubMed
- Brncic N, Viskovic I, Peric R, et al. Accidental plant poisoning with Colchicum autumnale: report of two cases. Croat Med J 2001;42(6):673-5.
- Sundov Z, Nincevic Z, Definis-Gojanovic M, et al. Fatal colchicine poisoning by accidental ingestion of meadow saffron-case report. Forensic Sci Int 2005;149(2-3):253-6. PubMed
- Boisramé-Helms J, Rahmani H, Stiel L, Tournoud C, Sauder P. Extracorporeal life support in the treatment of colchicine poisoning. Clin Toxicol (Phila) 2015;53(8):827-9.
- Razinger G, Kozelj G, Gorjup V, Grenc D, Brvar M. Accidental poisoning with autumn crocus (Colchicum autumnale): a case series. Clin Toxicol (Phila). 2021 Jun;59(6):493-9.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Rabeprazole Is Linked to Lower Levels of 9 Nutrients
Natural Medicines records Rabeprazole as a medicine that can lower these. This is not an interaction with Autumn Crocus — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Rabeprazole nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Autumn Crocus and Rabeprazole Together: Common Questions
Is it safe to take Autumn Crocus with Rabeprazole?
Do Autumn Crocus and Rabeprazole have any of the same side effects?
How was the Autumn Crocus and Rabeprazole combination checked?
Does Autumn Crocus interact with any other medications?
Does Rabeprazole interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Rabeprazole and Autumn Crocus?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.