Beer - Aspirin, Caffeine, Hydrocodone Interaction
Herbal: Beer
Drug: Aspirin, Caffeine, Hydrocodone
Brand names:
Damason-P
Medical Content Editor Dr. Brian Staiger, PharmD
Last updated
May 04, 2025
Interaction Details
Aspirin, Caffeine, Hydrocodone is classified as belonging to the following category: Cns Depressants
Concomitant use may increase sedative and other adverse effects.
Concomitant use of alcohol with CNS depressants can increase sedative and other adverse effects, potentially through inhibition of the metabolism of certain CNS depressants.
Interaction Rating
Likelihood of Occurrence
LikelyWell-controlled human studies have demonstrated the likely existence of this interaction
References
- Fraser AG. Pharmacokinetic interactions between alcohol and other drugs. Clin Pharmacokinet 1997;33:79-90.
Interaction Details
Aspirin, Caffeine, Hydrocodone is classified as belonging to the following category: Nonsteroidal Anti-Inflammatory Drugs (Nsaids)
Concomitant use may increase the risk of gastrointestinal (GI) bleeding.
Concomitant use of NSAIDs with alcohol can increase the risk of GI bleeding.
Interaction Rating
Likelihood of Occurrence
ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
References
- Fraser AG. Pharmacokinetic interactions between alcohol and other drugs. Clin Pharmacokinet 1997;33:79-90.
Interaction Details
Aspirin, Caffeine, Hydrocodone is classified as belonging to the following category: Narcotic Drugs
Concomitant use of large amounts of alcohol may decrease the metabolism of narcotic drugs.
Concomitant consumption of large amounts of alcohol can decrease the metabolism of narcotic drugs.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Fraser AG. Pharmacokinetic interactions between alcohol and other drugs. Clin Pharmacokinet 1997;33:79-90.
Interaction Details
Aspirin, Caffeine, Hydrocodone is classified as belonging to the following category: Aspirin
Concomitant use may increase the risk of gastrointestinal (GI) bleeding.
Concomitant use of aspirin with alcohol can increase the risk of GI bleeding. Conversely, some clinical research suggests that beer can significantly decrease the area under the curve (AUC) and maximum plasma concentration of aspirin, indicating decreased bioavailability.
Interaction Rating
Likelihood of Occurrence
PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
References
- Fraser AG. Pharmacokinetic interactions between alcohol and other drugs. Clin Pharmacokinet 1997;33:79-90.
- Odou, P., Barthelemy, C., and Robert, H. Influence of seven beverages on salicylate disposition in humans. J Clin Pharm Ther 2001;26(3):187-193.
Beer Overview
Beer is a popular beverage made from fermented sugars derived from starch-based materials, such as malted barley. Beer contains minerals like magnesium, potassium, selenium, and B vitamins, as well as flavonoids, especially in darker beers. These flavonoids, along with other compounds like xanthohumol from hops, have been studied for potential health benefits.
Some research suggests that beer, particularly its polyphenolic compounds, may have antioxidant effects, which could contribute to protection against atherosclerotic cardiovascular disease. Moderate beer consumption has also been linked to potential benefits for bone health, cardiovascular health, and even anticancer effects, although these effects can vary based on individual factors and consumption patterns. However, excessive alcohol consumption, including beer, can lead to negative health effects such as increased risk of cardiovascular disease, hypertension, and other conditions.
Beer - More Interactions
Beer interacts with 896 drugs
Interaction Rating Key
These severity listings are for informational use only. Never start, stop or otherwise change your therapy before speaking with your provider.
| Major | The combined use of these agents is strongly discouraged as serious side effects or other negative outcomes could occur. |
| Moderate | Use cautiously under the care of a healthcare professional or avoid this combination. A significant interaction or negative outcome could occur. |
| Minor | Be aware that there is a chance of an interaction. Watch for warning signs of a potential interaction. |
| Unknown | No interactions have been reported or no interaction data is currently available. |
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Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Drug descriptions are provided by MedlinePlus.
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