Broccoli Sprout + Paliperidone
Paliperidone brand name: Invega.
We found no known interaction between Broccoli Sprout and Paliperidone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Broccoli Sprout and Paliperidone
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Paliperidone and Broccoli Sprout in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Broccoli Sprout safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Paliperidone
Interactions in our licensed database are recorded against drug classes, not just single drug names. Paliperidone is filed under 5 classifications — including antipsychotic drugs, qt interval-prolonging drugs, photosensitizing drugs. Broccoli Sprout has documented interactions with 2 drug classes — the most serious being cytochrome p450 1a2 (cyp1a2) substrates (minor) and cytochrome p450 2a6 (cyp2a6) substrates (minor) — and none of Paliperidone’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Broccoli Sprout Does Interact With Other Medications
Broccoli Sprout has 187 minor known drug interactions in our database — Paliperidone isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Broccoli Sprout
We haven’t checked that one against Broccoli Sprout yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Broccoli Sprout. Pick one to open its full report.
Broccoli Sprout in Pregnancy & Breastfeeding
When COOKED broccoli sprouts are consumed in amounts commonly found in foods. Broccoli sprout is considered safe for dietary consumption provided the sprouts are grown in accordance with food safety recommendations developed by the US Food and Drug Administration (FDA) and are cooked prior to eating.
When RAW broccoli sprouts are consumed in amounts commonly found in foods. There is evidence that uncooked broccoli sprouts may be contaminated with bacteria, including Listeria monocytogenes, Salmonella, or Escherichia coli O157:H7. Pregnant individuals are particularly susceptible to these food-borne illnesses, and becoming infected can increase the risk of miscarriage, stillbirth, premature birth, or neonatal infection. There is insufficient reliable information available about the safety of broccoli sprout extract during pregnancy or lactation; avoid using.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
What Paliperidone Is Prescribed For, and What Broccoli Sprout Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Paliperidone is a prescription medicine with approved uses on its FDA label. Broccoli Sprout is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Paliperidone is prescribed for: Paliperidone treats schizophrenia and schizoaffective disorder. The extended-release tablets (Invega and generic paliperidone) are approved for schizophrenia in adults and adolescents ages 12–17, and for schizoaffective disorder in adults. Several injectable formulations are also available, each with specific roles. Invega Sustenna and Erzofri extended-release are once-monthly injections approved for schizophrenia and schizoaffective disorder in adults.
Read the rest of what Paliperidone is prescribed for
Invega Trinza is a once-every-3-month injection for schizophrenia in adults who have already been stabilized on a once-monthly paliperidone palmitate injection for at least four months. Invega Hafyera is a once-every-6-month injection for schizophrenia in adults already stabilized on a once-monthly or every-3-month paliperidone palmitate injection.
Broccoli Sprout has been studied for:
-
Schizophrenia studied, not established Broccoli Sprout has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Broccoli Sprout for schizophrenia
Although there has been interest in using oral broccoli sprout extract for schizophrenia, there is insufficient reliable information about the clinical effects of broccoli sprout extract for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Paliperidone on your own; if you are taking Broccoli Sprout for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Broccoli Sprout or Paliperidone
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Broccoli Sprout or Paliperidone, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Paliperidone
This page covers Broccoli Sprout only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Paliperidone page lists 64 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), American Hellebore (major), Arsenic (major), Cesium (major) and Ephedra (major).
By severity: 9 major · 44 moderate · 11 minor.
From our pharmacist’s overview on the Paliperidone page
“Paliperidone (Invega) is an antipsychotic for schizophrenia and related conditions that can stretch the heart's QT interval on its own, so this list warrants real vigilance. Nine of the 64 ingredients on file carry a major rating, and most either prolong that QT interval further (grapefruit in large amounts is one of them) or intensify…”
Reviewed by 2 · Jul 18, 2026
Taking Broccoli Sprout as Part of a Dietary Supplement Product? Check It for Interactions
We hold 184 real supplement products containing Broccoli Sprout, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Broccoli Sprout. Even though Broccoli Sprout itself has no known interaction with Paliperidone, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Broccoli Sprout and Paliperidone Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#561 of 1,452 supplements looked up here in the last 7 days
#1,616 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Broccoli Sprout reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Broccoli Sprout and Paliperidone records this page draws on were last updated July 10, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Broccoli Sprout
What is Broccoli Sprout?
- Antioxidant support
- Detoxification support
- General heart health
- Anti-inflammatory support
- Digestive and gut health
Broccoli sprouts are young broccoli seedlings rich in a compound called sulforaphane, which is being studied for antioxidant, anti-inflammatory, and detoxification effects. Early research is promising for some uses, but high-quality human evidence is still limited, so they should be viewed as a healthy food rather than a proven treatment. As food they are generally safe, but talk to your pharmacist or doctor before using concentrated supplements, especially during pregnancy or breastfeeding.
Brassica oleracea var. italica · Brassicaceae · Young sprouts (seedlings) of the broccoli plant · Fresh sprouts, powders, capsules, tablets, and standardized extracts (often labeled as containing sulforaphane or glucoraphanin)
An interaction check asks whether these two react with each other — it does not ask whether Broccoli Sprout is a good idea for someone in your situation. Here is what our Broccoli Sprout record says about it on its own.
Broccoli Sprout: dosing
There is no official standardized dose for broccoli sprouts or their extracts. Studies have used different forms and amounts, often described by the amount of glucoraphanin or sulforaphane, which makes comparison difficult.If you are eating them as food, a serving as part of a balanced diet is reasonable. If you choose a supplement, follow the directions on the product label and choose a reputable brand.
From our Broccoli Sprout monograph — the full record covers uses, side effects and every documented interaction.
About Paliperidone
What Is Paliperidone Used For?
Brand name: Invega
Paliperidone treats schizophrenia and schizoaffective disorder. The extended-release tablets (Invega and generic paliperidone) are approved for schizophrenia in adults and adolescents ages 12–17, and for schizoaffective disorder in adults.
Several injectable formulations are also available, each with specific roles. Invega Sustenna and Erzofri extended-release are once-monthly injections approved for schizophrenia and schizoaffective disorder in adults. Invega Trinza is a once-every-3-month injection for schizophrenia in adults who have already been stabilized on a once-monthly paliperidone palmitate injection for at least four months. Invega Hafyera is a once-every-6-month injection for schizophrenia in adults already stabilized on a once-monthly or every-3-month paliperidone palmitate injection.
Most-Reported Side Effects for Paliperidone
From FAERS, the FDA’s public side-effect reporting system (52,996 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Broccoli Sprout
Browse every other medication we’ve checked against Broccoli Sprout — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
187 interactions
- Theophylline ›
- Naproxen ›
- Estradiol ›
- Propranolol ›
- Verapamil ›
- Acetaminophen ›
- Diazepam ›
- Lofepramine ›
- Nortriptyline ›
- Bendamustine ›
- Caffeine (otc Drug) ›
- Cyclobenzaprine ›
- Desipramine ›
- Riluzole ›
- Vortioxetine ›
- Warfarin Sodium ›
- Asenapine ›
- Caffeine (prescription Drug) ›
- Clomipramine ›
- Clozapine ›
- Flutamide ›
- Imipramine ›
- Propafenone ›
- Ropinirole ›
- Tasimelteon ›
- Tizanidine ›
- Zileuton ›
- Agomelatine ›
- Amitriptyline ›
- Anagrelide ›
- Bendamustine Hydrochloride ›
- Chlordiazepoxide ›
- Clopidogrel ›
- Enasidenib ›
- Estrogen ›
- Ethinyl Estradiol ›
- Etonogestrel ›
- Fenfluamine ›
- Fezolinetant ›
- Fluvoxamine ›
- Grepafloxacin ›
- Haloperidol ›
- Levobupivacaine ›
- Mexiletine ›
- Mirtazapine ›
- Naproxen Sodium ›
- Oestrogen ›
- Olanzapine ›
- Ondansetron ›
- Paracetamol ›
- Pentazocine ›
- Perampanel ›
- Pirfenidone ›
- Pomalidomide ›
- Propranolol Hydrochloride ›
- Ramelteon ›
- Rasagiline ›
- Ropivacaine ›
- Tacrine ›
- Tipranavir ›
Showing 60 of 187 minor interactions — see all 187 on the Broccoli Sprout page.
No interaction 2,642 drugs checked — show the list
We also checked Broccoli Sprout against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Sertraline ›
- Ivermectin ›
- Testosterone ›
- Abemaciclib ›
- Losartan Potassium ›
- Aspirin ›
- Metoprolol ›
- Rosuvastatin ›
- Escitalopram ›
- Rivaroxaban ›
- Atorvastatin ›
- Docusate ›
- Methamphetamine ›
- Tirzepatide ›
- Tadalafil ›
- Ibuprofen ›
- Valacyclovir ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Isotretinoin ›
- Lisinopril ›
- Amlodipine Besylate ›
- Methotrexate ›
- Amphetamine ›
- Bupropion ›
- Doxycycline ›
- Fluoxetine ›
- Azithromycin ›
- Acyclovir ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Levothyroxine, Liothyronine ›
- Quetiapine ›
- Clonazepam ›
- Omeprazole ›
- Duloxetine ›
- Letrozole ›
- Citalopram ›
- Methylene Blue ›
- Buspirone ›
- Ciprofloxacin ›
- Bisoprolol ›
- Candesartan Cilexetil ›
- Amoxicillin, Clavulanate Potassium ›
- Dapsone ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
- Cephalexin ›
- Cyclopentolate ›
- Acetylsalicylic Acid ›
Showing the 60 most looked-up of 2,642 medications checked with no known interaction — see the full Broccoli Sprout list.
Broccoli Sprout References
The 8 references that drive our Broccoli Sprout monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
- Pezdirc KB, Hure AJ, Blumfield ML, Collins CE. Listeria monocytogenes and diet during pregnancy; balancing nutrient intake adequacy v. adverse pregnancy outcomes. Public Health Nutr 2012;15(12):2202-9.
- Gorski L, Flaherty D, Duhe JM. Comparison of the stress response of Listeria monocytogenes strains with sprout colonization. J Food Prot 2008;71(8):1556-1562. PubMed
- Fahey JW, Ourisson PJ, Degnan FH. Pathogen detection, testing, and control in fresh broccoli sprouts. Nutr J 2006;5:13. PubMed
- Rajkowski KT, Boyd G, Thayer DW. Irradiation D-values for Escherichia coli O157:H7 and Salmonella sp. on inoculated broccoli seeds and effects of irradiation on broccoli sprout keeping quality and seed viability. J Food Prot 2003;66(5):760-766. PubMed
- Yoshida K, Ushida Y, Ishijima T, et al. Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World J Gastroenterol. 2015;21(35):10091-103. PubMed
- Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
- Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Broccoli Sprout and Paliperidone Together: Common Questions
Is it safe to take Broccoli Sprout with Paliperidone?
Are Broccoli Sprout and Paliperidone used for the same thing?
How was the Broccoli Sprout and Paliperidone combination checked?
Does Broccoli Sprout interact with any other medications?
Does Paliperidone interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Keep Exploring
Still Have a Question About Paliperidone and Broccoli Sprout?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.