Drug & supplement interaction

Celery + Alectinib Hydrochloride

Alectinib Hydrochloride brand name: Alecensa.

Minor Interaction
The bottom line Minor

Celery has a minor interaction with Alectinib Hydrochloride. Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.

Read the full interaction report
SeverityMinor
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Celery and Alectinib Hydrochloride

Here is the interaction we found between these two, with the evidence behind it.

Minor

PHOTOSENSITIZING DRUGS

Why this applies to Alectinib Hydrochloride

Alectinib Hydrochloride falls under PHOTOSENSITIZING DRUGS — the group Celery interacts with.

Theoretically, celery might increase the risk of photosensitivity reactions when taken with photosensitizing drugs.
Laboratory research shows that celery contains photosensitizing agents such as phenols and psoralens.
Severity Minor Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version. Alectinib (Alecensa) already makes your skin more sensitive to sunlight, so sunburn and rashes can show up faster than usual while you're on it. Celery contains natural compounds called psoralens that can do the same thing. Put them together and, in theory, your skin might be a little more likely to burn or react in the sun. This isn't about how your body processes the cancer medicine, so celery shouldn't change how well alectinib fights your lung cancer.

Honestly, this is a minor concern based on weak, mostly lab-level evidence. Eating celery as food is very unlikely to matter much. Concentrated celery seed supplements are more of a question mark. Either way, wear sunscreen and a hat, and check with your oncology team or pharmacist before adding supplements.

References
  1. Gral N, Beani JC, Bonnot D, et al. [Plasma levels of psoralens after celery ingestion]. Ann Dermatol Venereol 1993;120:599-603.
  2. Weber, I. C., Davis, C. P., and Greeson, D. M. Phytophotodermatitis: the other "lime" disease. J Emerg.Med 1999;17(2):235-237. PubMed
  3. Lombaert, G. A., Siemens, K. H., Pellaers, P., Mankotia, M., and Ng, W. Furanocoumarins in celery and parsnips: method and multiyear Canadian survey. J AOAC Int 2001;84(4):1135-1143. DOI
  4. Gorgus, E., Lohr, C., Raquet, N., Guth, S., and Schrenk, D. Limettin and furocoumarins in beverages containing citrus juices or extracts. Food Chem.Toxicol. 2010;48(1):93-98. PubMed
  5. Beier, R. C., Ivie, G. W., Oertli, E. H., and Holt, D. L. HPLC analysis of linear furocoumarins (psoralens) in healthy celery (Apium graveolens). Food Chem.Toxicol. 1983;21(2):163-165. PubMed

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Celery Also Interacts With Other Medications

Celery has 449 moderate, 201 minor known drug interactions in our database — the Alectinib Hydrochloride one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Celery

Covers the 2,830 medications we’ve checked against Celery. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Alectinib Hydrochloride

This page covers Celery only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Alectinib Hydrochloride page lists 74 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Alfalfa (moderate).

By severity: 4 major · 60 moderate · 10 minor.

From our pharmacist’s overview on the Alectinib Hydrochloride page

“Alectinib (Alecensa) treats ALK-positive lung cancer, and because your liver already has to tolerate this drug, check this page before adding any supplement, not after. Of the 74 ingredients on file, 38 can add stress to the liver, and three of the four major-rated entries (beer, wine, and Siberian cocklebur) are the clearest examples…”

Reviewed by 2 · Jul 18, 2026

Open the Alectinib Hydrochloride interaction page

One more smart check

Taking Celery as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1,687 real supplement products containing Celery, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Celery. Your product may carry other ingredients that interact with Alectinib Hydrochloride too, on top of Celery — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Celery and Alectinib Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Celery
Top 25%

#168 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Alectinib Hydrochloride
Steady interest

#1,823 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Celery

What is Celery?

Celery
  • High blood pressure
  • Fluid retention (diuretic)
  • Joint pain and inflammation
  • Anxiety and sleep
  • Digestive support

Celery is a common vegetable that is also taken as a seed extract or oil supplement, mainly for blood pressure, fluid retention, and joint discomfort. Human evidence for these supplement uses is limited and mostly preliminary, so it should not replace proven treatments. Celery is generally safe as food, but concentrated supplements and possible allergic reactions warrant caution.

Read the full Celery monograph & all interactions
Medication

About Alectinib

What Is Alectinib Used For?

Brand name: Alecensa

Alecensa (alectinib) is used in adults with non-small cell lung cancer (NSCLC) whose tumors test positive for a gene change called ALK (anaplastic lymphoma kinase). Your tumor must be confirmed ALK-positive by an FDA-approved test before starting treatment.

Alecensa is approved for two situations: as adjuvant treatment (after surgery to remove the tumor, for tumors that are large enough or have spread to nearby lymph nodes) to help prevent the cancer from coming back, and for metastatic NSCLC (cancer that has already spread to other areas of the body).

See full Alectinib drug information
Keep checking

Other Drugs & Celery

Browse every other medication we’ve checked against Celery — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
449Moderate
201Minor
2,179No known interaction
Moderate

449 interactions

Showing 60 of 449 moderate interactions — see all 449 on the Celery page.

Minor

201 interactions

Showing 60 of 201 minor interactions — see all 201 on the Celery page.

No interaction 2,179 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Celery and Alectinib Hydrochloride Together: Common Questions

Can you take Celery with Alectinib Hydrochloride?
There is only a minor interaction, which is usually not serious. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Celery and Alectinib Hydrochloride interaction?
We rate it Minor. This interaction is generally not clinically significant, but it remains worth noting and discussing with your pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.