Ceylon Cinnamon + Ciprofloxacin
Ciprofloxacin brand names: Cipro, Ciprobay, Cipro XR, Ciloxan, Cipro IV, and others.
We found no known interaction between Ceylon Cinnamon and Ciprofloxacin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Ciprofloxacin states a food rule worth keeping to, and the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.
Ceylon Cinnamon and Ciprofloxacin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Ciprofloxacin and Ceylon Cinnamon in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Ceylon Cinnamon safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Why No Interaction Is Listed for Ciprofloxacin
Interactions in our licensed database are recorded against drug classes, not just single drug names. Ciprofloxacin is filed under 12 classifications — including quinolone antibiotics, organic anion-transporting polypeptide substrates (oatp), cytochrome p450 1a2 (cyp1a2) inhibitors. Ceylon Cinnamon has documented interactions with 2 drug classes — the most serious being antidiabetes drugs (moderate) and antihypertensive drugs (moderate) — and none of Ciprofloxacin’s classifications are among them.
Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.
Ceylon Cinnamon Does Interact With Other Medications
Ceylon Cinnamon has 258 moderate known drug interactions in our database — Ciprofloxacin isn’t one of them. If you take anything else, check it against the full list below.
Check Another of Your Medications Against Ceylon Cinnamon
We haven’t checked that one against Ceylon Cinnamon yet — ask our pharmacists directly.
Covers the 2,830 medications we’ve checked against Ceylon Cinnamon. Pick one to open its full report.
Ceylon Cinnamon in Pregnancy & Breastfeeding
When consumed in amounts commonly found in foods.
When used orally in amounts greater than those found in foods. Fetal abnormalities have been reported in animals.
When consumed in amounts commonly found in foods. There is insufficient reliable information available about the safety of Ceylon cinnamon in amounts greater than those found in foods.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
Some Ciprofloxacin Products Have a Food Rule — Ceylon Cinnamon Should Not Break It
At least one FDA label for a product containing Ciprofloxacin says to take it with food. If you take Ceylon Cinnamon on an empty stomach out of habit, keep them separate — and take Ciprofloxacin with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Ciprofloxacin products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
With Dairy Products Concomitant administration of CIPRO with dairy products (like milk or yogurt) or calcium-fortified juices alone should be avoided since decreased absorption is possible; however, CIPRO may be taken with a meal that contains these products.
From the Dosage and Administration section of the FDA label we read for Ciprofloxacin — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
What Ciprofloxacin Is Prescribed For, and What Ceylon Cinnamon Has Been Studied For
These two come up together because they touch the same health topic — not because they do the same job. Ciprofloxacin is a prescription medicine with approved uses on its FDA label. Ceylon Cinnamon is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.
Ciprofloxacin is prescribed for: Ciprofloxacin belongs to a class of antibiotics called fluoroquinolones. It's prescribed to treat bacterial infections in many parts of the body — including the urinary tract, skin, lungs, bones, joints, and digestive system. It's also used to protect against or treat anthrax and plague after exposure. Because ciprofloxacin carries real risks, it's reserved for milder conditions like sinus infections, simple bladder infections, and flare-ups of chronic bronchitis only when there are no safer alternatives available.
Ceylon Cinnamon has been studied for:
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Diarrhea studied, not established Ceylon Cinnamon has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows
Ceylon Cinnamon for diarrhea
Although there has been interest in using oral Ceylon cinnamon for diarrhea, there is insufficient reliable information about the clinical effects of Ceylon cinnamon for this purpose.
Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Ciprofloxacin on your own; if you are taking Ceylon Cinnamon for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.
Questions About Ceylon Cinnamon or Ciprofloxacin
These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Ceylon Cinnamon or Ciprofloxacin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:
- Can You Take Ceylon Cinnamon With Prozac (Fluoxetine)? ›
- Does Ginger Water Interfere With Amoxicillin-Clavulanate? ›
- How Can I Prevent Stomach Pain From Amoxicillin-Clavulanate? ›
- Help With Taking Vitamins After Clarithromycin ›
Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.
See Every Supplement That Interacts With Ciprofloxacin
This page covers Ceylon Cinnamon only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Ciprofloxacin page lists 163 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Apple (major), Asarabacca (major), Beer (major) and Grapefruit (major).
By severity: 8 major · 133 moderate · 22 minor.
From our pharmacist’s overview on the Ciprofloxacin page
“A glass of apple or grapefruit juice can sharply cut how much ciprofloxacin (Cipro) your body absorbs, because these juices block a transporter the antibiotic needs to reach the bloodstream. That is one of eight major-rated risks among the 163 supplement and herbal ingredients on file, and I treat this list as a genuine warning rather…”
Reviewed by 2 · Jul 18, 2026
Taking Ceylon Cinnamon as Part of a Dietary Supplement Product? Check It for Interactions
We hold 362 real supplement products containing Ceylon Cinnamon, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Ceylon Cinnamon. Even though Ceylon Cinnamon itself has no known interaction with Ciprofloxacin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Ceylon Cinnamon and Ciprofloxacin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#322 of 1,452 supplements looked up here in the last 7 days
#48 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Ceylon Cinnamon reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Ceylon Cinnamon and Ciprofloxacin records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Ceylon Cinnamon
What is Ceylon Cinnamon?
- Blood sugar support
- High cholesterol
- Indigestion and gas
- Antimicrobial
- General flavoring and culinary use
Ceylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and digestion. Evidence for most health benefits is limited and mixed, but as a food it is generally safe and contains far less coumarin than common cassia cinnamon. Talk with your pharmacist or doctor before taking concentrated supplements, especially if you have a health condition or take medications.
Cinnamomum verum · Lauraceae · Inner bark (and bark-derived essential oil) · Ground spice, capsules, powder, extracts, tea, essential oil
An interaction check asks whether these two react with each other — it does not ask whether Ceylon Cinnamon is a good idea for someone in your situation. Here is what our Ceylon Cinnamon record says about it on its own.
Ceylon Cinnamon: dosing
There is no official, standardized dose of Ceylon cinnamon for any health condition. Amounts used in studies have varied widely, and many studies used cassia cinnamon, so results may not apply to Ceylon products.If you choose to take a supplement, follow the directions on the product label and do not exceed the recommended amount.
From our Ceylon Cinnamon monograph — the full record covers uses, side effects and every documented interaction.
About Ciprofloxacin
What Is Ciprofloxacin Used For?
Brand names: Cipro, Ciprobay, Cipro XR, Ciloxan, Cipro IV, Otiprio
Ciprofloxacin belongs to a class of antibiotics called fluoroquinolones. It's prescribed to treat bacterial infections in many parts of the body — including the urinary tract, skin, lungs, bones, joints, and digestive system. It's also used to protect against or treat anthrax and plague after exposure.
Because ciprofloxacin carries real risks, it's reserved for milder conditions like sinus infections, simple bladder infections, and flare-ups of chronic bronchitis only when there are no safer alternatives available.
Other Drugs & Ceylon Cinnamon
Browse every other medication we’ve checked against Ceylon Cinnamon — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
258 interactions
- Diltiazem ›
- Nifedipine ›
- Insulin (rdna) ›
- Propranolol ›
- Hydrochlorothiazide ›
- Verapamil ›
- Glyburide ›
- Insulin (pork) ›
- Hydralazine ›
- Insulin (human) ›
- Trichlormethiazide ›
- Acarbose ›
- Bendroflumethiazide ›
- Insulin Glargine ›
- Lisinopril ›
- Metolazone ›
- Minoxidil ›
- Nicardipine ›
- Prazosin ›
- Semaglutide ›
- Spironolactone ›
- Timolol ›
- Acebutolol ›
- Acetazolamide ›
- Ambrisentan ›
- Amiloride ›
- Atenolol ›
- Betaxolol ›
- Candesartan Cilexetil ›
- Captopril ›
- Carteolol ›
- Carvedilol ›
- Chlorpropamide ›
- Chlorthalidone ›
- Cyclothiazide ›
- Enalapril Maleate ›
- Exenatide ›
- Felodipine ›
- Glipizide ›
- Glucagon ›
- Guanethidine Monosulfate ›
- Iloprost ›
- Indapamide ›
- Insulin Lispro ›
- Irbesartan ›
- Labetalol ›
- Mannitol ›
- Metformin ›
- Methyclothiazide ›
- Methyldopa ›
- Metoprolol ›
- Nadolol ›
- Nebivolol ›
- Nimodipine ›
- Olmesartan Medoxomil ›
- Oxprenolol ›
- Pindolol ›
- Quinapril ›
- Repaglinide ›
- Reserpine ›
Showing 60 of 258 moderate interactions — see all 258 on the Ceylon Cinnamon page.
No interaction 2,571 drugs checked — show the list
We also checked Ceylon Cinnamon against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Warfarin Sodium ›
- Prednisone ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Amoxicillin ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Methylene Blue ›
- Duloxetine ›
- Letrozole ›
- Buspirone ›
- Citalopram ›
- Naproxen ›
- Levothyroxine, Liothyronine ›
- Acetaminophen, Oxycodone ›
- Dapsone ›
- Diazepam ›
- Cyclopentolate ›
- Cephalexin ›
- Roxithromycin ›
- Pegunigalsidase Alfa-iwxj ›
- Atorvastatin Calcium ›
- Acetaminophen, Dextromethorphan, Doxylamine ›
Showing the 60 most looked-up of 2,571 medications checked with no known interaction — see the full Ceylon Cinnamon list.
Ceylon Cinnamon References
The 22 references that drive our Ceylon Cinnamon monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Choi HK, Jung GW, Moon KH, et al. Clinical study of SS-Cream in patients with lifelong premature ejaculation. Urology 2000;55:257-61. PubMed
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Anderson RA, Broadhurst CL, Polansky MM, et al. Isolation and Characterization of Polyphenol Type-A Polymers from Cinnamon with Insulin-like Biological Activity. J Agric Food Chem 2004;52:65-70. PubMed
- Jarvill-Taylor KJ, Anderson RA, Graves DJ. A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes. J Am Coll Nutr 2001;20:327-36. PubMed
- Onderoglu S, Sozer S, Erbil KM, et al. The evaluation of long-term effcts of cinnamon bark and olive leaf on toxicity induced by streptozotocin administration to rats. J Pharm Pharmacol 1999;51:1305-12.
- Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
- Ranasinghe P, Jayawardena R, Galappaththy P, et al. Response to Akilen et al. Efficacy and safety of 'true' cinnamon (Cinnamomum zeylanicum) as a pharmaceutical agent in diabetes: a systematic review and meta-analysis. Diabet Med 2013 Apr;30(4):506-7.
- Oliveira JdA, da Silva IC, Trindade LA, et al. Safety and tolerability of essential oil from Cinnamomum zeylanicum blume leaves with action on oral candidosis and its effect on the physical properties of the acylic resin. Evid Based Complement Alternat Me
- Ranasinghe P, Pigera S, Premakumara GA, et al. Medicinal properties of 'true' cinnamon (Cinnamomum zeylanicum): a systematic review. BMC Complement Altern Med 2013;13:275. PubMed
- Ranasinghe P, Galappaththy P. Health benefits of Ceylon cinnamon (Cinnamomum zeylanicum): a summary of the current evidence. Ceylon Med J 2016;61(1):1-5. PubMed
- Nyadjeu P, Dongmo A, Nguelefack TB, Kamanyi A. Antihypertensive and vasorelaxant effects of Cinnamomum zeylanicum stem bark aqueous extracts. J Complement Integr Med 2011;8.
- Wansi SL, Nyadjeu P, Ngamga D, et al. Blood pressure lowering effect of the ethanol extract from the stembark of Cinnamomum zeylanicum (lauraceae) in rats. Pharmacol online 2007;3:166-76.
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
- Ranasinghe P, Jayawardena R, Pigera S, et al. Evaluation of pharmacodynamic properties and safety of Cinnamomum zeylanicum (Ceylon cinnamon) in healthy adults: a phase I clinical trial. BMC Complement Altern Med 2017;17(1):550. PubMed
- Zareie A, Sahebkar A, Khorvash F, Bagherniya M, Hasanzadeh A, Askari G. Effect of cinnamon on migraine attacks and inflammatory markers: A randomized double-blind placebo-controlled trial. Phytother Res 2020;34(11):2945-52. PubMed
- Zobeiri M, Parvizi F, Shahpiri Z, et al. Evaluation of the effectiveness of cinnamon oil soft capsule in patients with functional dyspepsia: A randomized double-blind placebo-controlled clinical trial. Evid Based Complement Alternat Med 2021;2021:6634115. PubMed
- Chase C, Doyle A, John SS, Laurent T, Griffith S. Post-operative haemorrhage secondary to cinnamon use. A case report. Int J Surg Case Rep 2022;95:107179. PubMed
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Ciprofloxacin Is Linked to Lower Levels of 11 Nutrients
Natural Medicines records Ciprofloxacin as a medicine that can lower these. This is not an interaction with Ceylon Cinnamon — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
- BIOTIN›
- CALCIUM›
- FOLIC ACID›
- IRON›
- MAGNESIUM›
- RIBOFLAVIN›
- THIAMINE›
- VITAMIN B12›
- VITAMIN B6›
- VITAMIN K›
- ZINC›
Read the full Ciprofloxacin nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Ceylon Cinnamon and Ciprofloxacin Together: Common Questions
Is it safe to take Ceylon Cinnamon with Ciprofloxacin?
Do Ceylon Cinnamon and Ciprofloxacin have any of the same side effects?
Should I take Ceylon Cinnamon and Ciprofloxacin at the same time of day?
Are Ceylon Cinnamon and Ciprofloxacin used for the same thing?
How was the Ceylon Cinnamon and Ciprofloxacin combination checked?
Does Ceylon Cinnamon interact with any other medications?
Does Ciprofloxacin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.