Drug & supplement interaction

Chenopodium Oil + Moxifloxacin

Moxifloxacin brand name: Avelox.

Moderate Interaction
Medically reviewed by · Updated October 2026
The bottom line Moderate

Chenopodium Oil has a moderate interaction with Moxifloxacin. Theoretically, concomitant use of chenopodium oil with other photosensitizing drugs can increase the risk of adverse effects.

Read the full interaction report
SeverityModerate
LikelihoodProbable
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Chenopodium Oil and Moxifloxacin

Here is the interaction we found between these two, with the evidence behind it.

Moderate

PHOTOSENSITIZING DRUGS

Why this applies to Moxifloxacin

Moxifloxacin falls under PHOTOSENSITIZING DRUGS — the group Chenopodium Oil interacts with.

Theoretically, concomitant use of chenopodium oil with other photosensitizing drugs can increase the risk of adverse effects.
Chenopodium species are also associated with photosensitivity.
Severity Moderate Likelihood Probable Evidence D

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the simple version: moxifloxacin (Avelox) can already make your skin more sensitive to sunlight, which is true of many fluoroquinolone antibiotics. Some chenopodium (epazote) plants and oils are linked to that same kind of light sensitivity. So in theory, taking the two together could stack the effect and make your skin burn or react more easily in the sun.

I want to be honest about the strength of this one: it's theoretical, based on how these things behave rather than solid studies. This isn't about the oil changing how your body breaks down moxifloxacin, just a possible add-on sun-sensitivity risk. While you're on this antibiotic, it's smart to use sunscreen, cover up, and limit strong sun anyway. And since chenopodium oil can be toxic when taken internally, please run it by your pharmacist or doctor first.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Chenopodium Oil Also Interacts With Other Medications

Chenopodium Oil has 334 moderate known drug interactions in our database — the Moxifloxacin one above is one of them. If you take anything else, check it against the full list below.

Moderate 334 No known interaction 2,496 (incl. Moxifloxacin)
Taking anything else?

Check Another of Your Medications Against Chenopodium Oil

Covers the 2,830 medications we’ve checked against Chenopodium Oil. Pick one to open its full report.

From our Q&A

Questions About Chenopodium Oil or Moxifloxacin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Chenopodium Oil or Moxifloxacin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Moxifloxacin

This page covers Chenopodium Oil only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Moxifloxacin page lists 155 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), Apple (major), Arsenic (major) and Asarabacca (major).

By severity: 13 major · 121 moderate · 21 minor.

From our pharmacist’s overview on the Moxifloxacin page

“The supplement list for moxifloxacin (Avelox), a fluoroquinolone antibiotic, deserves genuine care, and the everyday items are the surprising part. Ordinary juices, apple, grapefruit, and sweet orange among them, block a transporter the drug needs for absorption and can cut how much reaches your blood, which for an antibiotic means the…”

Reviewed by 2 · Jul 18, 2026

Open the Moxifloxacin interaction page

One more smart check

Taking Chenopodium Oil as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Chenopodium Oil, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Chenopodium Oil. Your product may carry other ingredients that interact with Moxifloxacin too, on top of Chenopodium Oil — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Chenopodium Oil and Moxifloxacin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Chenopodium Oil
Top half

#646 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Moxifloxacin
Top half

#848 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Chenopodium Oil

What is Chenopodium Oil?

Chenopodium Oil
  • Intestinal worms (roundworm, hookworm)
  • Digestive upset and gas
  • Respiratory complaints
  • Skin conditions
  • As a culinary seasoning (epazote leaf)

Chenopodium oil is a strong-smelling essential oil from the epazote plant that was historically used to treat intestinal worms. It contains ascaridole, a compound that is quite toxic, and overdoses have caused serious harm, so it is no longer recommended for internal use. Safer modern deworming medicines exist, so talk with a pharmacist or doctor before using this oil.

Read the full Chenopodium Oil monograph & all interactions
Medication

About Moxifloxacin

What Is Moxifloxacin Used For?

Brand name: Avelox

Moxifloxacin tablets and moxifloxacin injection (given into a vein) treat certain bacterial infections in adults 18 and older. These include community acquired pneumonia, skin and skin structure infections, complicated infections inside the abdomen, acute bacterial sinusitis, and acute bacterial flare-ups of chronic bronchitis. Several tablet and injection labels also list plague. One injection label does not list plague.

Moxifloxacin eye drops (including Vigamox) treat bacterial conjunctivitis caused by susceptible bacteria. It only works on bacterial infections, and should be used only when bacteria are proven or strongly suspected.

See full Moxifloxacin drug information
Keep checking

Other Drugs & Chenopodium Oil

Browse every other medication we’ve checked against Chenopodium Oil — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
334Moderate
0Minor
2,495No known interaction
334 Moderate 2,495 No interaction
Moderate

334 interactions

Showing 60 of 334 moderate interactions — see all 334 on the Chenopodium Oil page.

No interaction 2,495 drugs checked — show the list

We also checked Chenopodium Oil against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,495 medications checked with no known interaction — see the full Chenopodium Oil list.

See the full Chenopodium Oil interactions page
See every supplement checked against Moxifloxacin, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Chenopodium Oil monograph › Uses, safety, and every drug interaction in one place Moxifloxacin supplement interactions › Every supplement checked against Moxifloxacin, ranked by severity Moxifloxacin drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Chenopodium Oil and Moxifloxacin Together: Common Questions

Can you take Chenopodium Oil with Moxifloxacin?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Chenopodium Oil and Moxifloxacin interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Moxifloxacin and Chenopodium Oil?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.