Drug & supplement interaction

Clubmoss + Clopidogrel

Clopidogrel brand name: Plavix.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Clubmoss and Clopidogrel in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Clubmoss and Clopidogrel

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Clopidogrel and Clubmoss in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Clubmoss safety at a glance

Clubmoss overall Use caution It contains toxic alkaloids and has limited safety data, so it should be used carefully if at all.
Pregnancy Possibly Unsafe When used orally; avoid using. Read the full pregnancy detail
Breastfeeding Possibly Unsafe When used orally; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Clopidogrel and Clubmoss? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Clopidogrel

Interactions in our licensed database are recorded against drug classes, not just single drug names. Clopidogrel is filed under 7 classifications — including cytochrome p450 2c9 (cyp2c9) substrates, anticoagulant/antiplatelet drugs, cytochrome p450 1a2 (cyp1a2) substrates. Clubmoss has documented interactions with 3 drug classes — the most serious being acetylcholinesterase (ache) inhibitors (moderate), anticholinergic drugs (moderate) and cholinergic drugs (moderate) — and none of Clopidogrel’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Clubmoss Does Interact With Other Medications

Clubmoss has 219 moderate known drug interactions in our database — Clopidogrel isn’t one of them. If you take anything else, check it against the full list below.

Moderate 219 No known interaction 2,611 (incl. Clopidogrel)
Taking anything else?

Check Another of Your Medications Against Clubmoss

Covers the 2,830 medications we’ve checked against Clubmoss. Pick one to open its full report.

What to actually watch for

What Clubmoss Itself Has Been Linked To

This is not an interaction — nothing below involves Clopidogrel. It is the side-effect record for Clubmoss on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Clubmoss, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • Wheezing Worth acting on Additional detail

    “Orally, no adverse effects have been reported; however, a thorough evaluation of safety outcomes has not been conducted. Additionally, clubmoss contains toxic alkaloids, which could cause serious adverse effects. When fir club moss (Lycopodium selago) is mistaken for clubmoss, cholinergic toxicity has been reported.”

    Clubmoss · Natural Medicines adverse-effect record, reported in asthma.

    2 sources cited
    1. 43721. Cullinan, P., Cannon, J., Sheril, D., and Newman, Taylor A. Asthma following occupational exposure to Lycopodium clavatum in condom manufacturers. Thorax 1993;48(7):774-775. PubMed
    2. 13193. Felgenhauer N, Zilker T, Worek F, Eyer P. Intoxication with huperzine A, a potent anticholinesterase found in the fir club moss. J Toxicol Clin Toxicol 2000;38:803-8.. PubMed

    “Occupational exposure to clubmoss spores, including cases associated with facilities that use the spores to coat condoms, has been reported to cause asthma.”

    Clubmoss · Natural Medicines adverse-effect record, reported in asthma.

    1 source cited
    1. 43721. Cullinan, P., Cannon, J., Sheril, D., and Newman, Taylor A. Asthma following occupational exposure to Lycopodium clavatum in condom manufacturers. Thorax 1993;48(7):774-775. PubMed
  • Sweating / Dizziness / Nausea Additional detail

    “Clubmoss (Lycopodium clavatum) might be mistaken for fir club moss (Lycopodium selago), which contains huperzine A, a constituent with strong inhibitory activity against acetylcholinesterase. In two case reports, fir club moss was mistaken for clubmoss and ingested as tea. This caused cholinergic toxicity with symptoms of sweating, nausea, dizziness, cramping, and slurred speech.”

    Clubmoss · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 13193. Felgenhauer N, Zilker T, Worek F, Eyer P. Intoxication with huperzine A, a potent anticholinesterase found in the fir club moss. J Toxicol Clin Toxicol 2000;38:803-8.. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Clubmoss — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Clopidogrel’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Clopidogrel column appears here.

Special populations

Clubmoss in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

When used orally; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

From our Q&A

Questions About Clubmoss or Clopidogrel

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Clubmoss or Clopidogrel, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Clopidogrel

This page covers Clubmoss only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Clopidogrel page lists 309 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Danshen (major), Grapefruit (major), Piracetam (major) and St. John's Wort (major).

By severity: 5 major · 258 moderate · 46 minor.

From our pharmacist’s overview on the Clopidogrel page

“Clopidogrel (Plavix) keeps platelets from sticking together after a stent, heart attack, or stroke, which makes this a list to take carefully. Of the 309 supplements and herbs on file, 202 carry blood-thinning or antiplatelet activity of their own and can stack bleeding risk on top of the drug's, while most of the rest change how the l…”

Reviewed by 2 · Jul 18, 2026

Open the Clopidogrel interaction page

How much people look this up

Where Clubmoss and Clopidogrel Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Clubmoss
Steady interest

#1,286 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Clopidogrel
Top 1%

#14 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Clubmoss reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Clubmoss and Clopidogrel records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Clubmoss

What is Clubmoss?

Clubmoss
  • Bladder and kidney complaints
  • Digestive upset
  • Skin irritation and chafing
  • Respiratory problems
  • Used in homeopathy

Clubmoss (Lycopodium clavatum) is a primitive plant with a long history in folk medicine and homeopathy, but there is very little reliable human research to show it works for any health condition. It contains potentially toxic alkaloids, so it should be used with great caution, and people who are pregnant or breastfeeding should avoid it. Talk with a pharmacist or doctor before trying it.

Lycopodium clavatum · Lycopodiaceae · Whole plant and spores · Powdered spores, dried herb, tinctures, teas, homeopathic preparations, capsules

An interaction check asks whether these two react with each other — it does not ask whether Clubmoss is a good idea for someone in your situation. Here is what our Clubmoss record says about it on its own.

Clubmoss: dosing

There is no established, well-studied dose for clubmoss. Because the amount of active and potentially toxic compounds can vary between products and plant sources, a safe dose has not been clearly defined.If you choose to use a clubmoss product, follow the directions on the label and do not exceed them. Homeopathic "Lycopodium" products are extremely diluted and are different from raw herb preparations.

From our Clubmoss monograph — the full record covers uses, side effects and every documented interaction.

Read the full Clubmoss monograph & all interactions
Medication

About Clopidogrel

What Is Clopidogrel Used For?

Brand name: Plavix

Clopidogrel tablets are used to reduce the risk of heart attack and stroke in people with acute coronary syndrome (ACS) — including unstable angina and non-ST-elevation or ST-elevation heart attacks — and in people with a history of recent heart attack, recent stroke, or established peripheral arterial disease. For ACS, it is typically given alongside aspirin.

It works by preventing platelets (blood cells that trigger clotting) from clumping together, which helps keep arteries open and lowers the chance of a dangerous clot forming.

Most-Reported Side Effects for Clopidogrel

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Dyspnea 10,950 reports
Myocardial infarction 10,227 reports
Fatigue 9,428 reports
Gastrointestinal haemorrhage 8,776 reports
Nausea 8,686 reports
See full Clopidogrel drug information
Keep checking

Other Drugs & Clubmoss

Browse every other medication we’ve checked against Clubmoss — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
219Moderate
0Minor
2,610No known interaction
219 Moderate 2,610 No interaction
Moderate

219 interactions

Showing 60 of 219 moderate interactions — see all 219 on the Clubmoss page.

No interaction 2,610 drugs checked — show the list

We also checked Clubmoss against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,610 medications checked with no known interaction — see the full Clubmoss list.

See the full Clubmoss interactions page
See every supplement checked against Clopidogrel, ranked by severity
Evidence & sources

Clubmoss References

The 3 references that drive our Clubmoss monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Felgenhauer N, Zilker T, Worek F, Eyer P. Intoxication with huperzine A, a potent anticholinesterase found in the fir club moss. J Toxicol Clin Toxicol 2000;38:803-8.. PubMed
  2. Orhan, I., Terzioglu, S., and Sener, B. Alpha-onocerin: an acetylcholinesterase inhibitor from Lycopodium clavatum. Planta Med. 2003;69(3):265-267.
  3. Cullinan, P., Cannon, J., Sheril, D., and Newman, Taylor A. Asthma following occupational exposure to Lycopodium clavatum in condom manufacturers. Thorax 1993;48(7):774-775. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Clubmoss and Clopidogrel Together: Common Questions

Is it safe to take Clubmoss with Clopidogrel?
We do not list a known interaction between Clubmoss and Clopidogrel. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Clubmoss and Clopidogrel combination checked?
Interactions in our licensed database are recorded against drug classes. Clopidogrel is filed under 7 classifications, and Clubmoss has documented interactions with 3 drug classes — none of Clopidogrel's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Clubmoss interact with any other medications?
Yes. Clubmoss has 219 documented drug interactions in our database — Clopidogrel is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Clopidogrel interact with any supplements?
Yes. Clopidogrel has documented interactions with 309 supplements in our database — Clubmoss is not one of them. The Clopidogrel interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Clubmoss monograph Uses, safety profile, and every drug interaction in one place Clopidogrel drug information The full plain-English guide to this medication Clopidogrel supplement interactions Every supplement checked against Clopidogrel, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Clopidogrel and Clubmoss?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.