Drug & supplement interaction

Heart's Ease + Pindolol

Pindolol brand names: Visken, Pindol.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Heart's Ease and Pindolol in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Heart's Ease and Pindolol

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Pindolol and Heart's Ease in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Heart's Ease at all — not against Pindolol, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Heart's Ease safety at a glance

Heart's Ease overall Use caution Generally considered low-risk in traditional use, but high-quality safety data are limited.
Pregnancy Avoid Not enough safety information, so it is best avoided during pregnancy.
Breastfeeding Avoid Not enough safety information, so it is best avoided while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Pindolol and Heart's Ease? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Pindolol’s Own FDA Label Lists

This is not an interaction — none of it involves Heart's Ease. These are the most notable effects listed in the ADVERSE REACTIONS section of Pindolol’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 10 of them are worth acting on rather than waiting out — marked below.

  • Memory problems Worth acting on
  • A slow heartbeat Worth acting on
  • Blood clots Worth acting on
  • Hallucinations Worth acting on
  • Heart failure Worth acting on
  • Fainting Worth acting on
  • Wheezing Worth acting on
  • Confusion Worth acting on
  • Shortness of breath Worth acting on mentioned in 5.2% of FDA reports for Pindolol
  • Chest pain Worth acting on

Showing the 10 most notable of 39 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Pindolol. Read the label on DailyMed › Where a percentage is shown, it is the share of 782 voluntary FDA FAERS reports for Pindolol that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Heart's Ease’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Heart's Ease side to compare — that is a limit of the record, not a statement that Heart's Ease has no side effects.

Everything else you take

See Every Supplement That Interacts With Pindolol

This page covers Heart's Ease only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Pindolol page lists 183 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Indian Snakeroot (major) and Tyramine (major).

By severity: 5 major · 151 moderate · 27 minor.

From our pharmacist’s overview on the Pindolol page

“People prescribed pindolol (Visken), a beta-blocker, are usually treating high blood pressure, and they are often the very people drawn to heart-friendly supplements like fish oil. That overlap is why this list of 183 ingredients deserves genuine care, starting with the five rated major.”

Reviewed by 2 · Jul 18, 2026

Open the Pindolol interaction page

One more smart check

Taking Heart's Ease as Part of a Dietary Supplement Product? Check It for Interactions

We hold 35 real supplement products containing Heart's Ease, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Heart's Ease. Even though Heart's Ease itself has no known interaction with Pindolol, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Heart's Ease and Pindolol Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Heart's Ease
Steady interest

#790 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Pindolol
Steady interest

#2,265 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Heart's Ease reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Heart's Ease and Pindolol records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Heart's Ease

What is Heart's Ease?

  • Skin conditions like eczema and cradle cap
  • Mild respiratory complaints (cough)
  • Mild inflammation
  • Diuretic (increasing urine flow)
  • General 'blood cleansing' tonic

Heart's Ease (Viola tricolor) is a traditional European herb used mostly for skin problems and mild coughs. Modern human evidence for these uses is very limited, so it should be seen as a gentle traditional remedy rather than a proven treatment. Talk to your pharmacist or doctor before using it, especially if you are pregnant, breastfeeding, or giving it to a child.

Viola tricolor · Violaceae · Above-ground flowering parts (herb) · Tea, dried herb, tincture, topical preparations, capsules

An interaction check asks whether these two react with each other — it does not ask whether Heart's Ease is a good idea for someone in your situation. Here is what our Heart's Ease record says about it on its own.

Heart's Ease: dosing

There is no well-established, standardized dose for Heart's Ease. Traditional use varies widely depending on whether it is taken as a tea, tincture, or applied to the skin.The safest approach is to follow the directions on the product label and to start with the lowest suggested amount.

From our Heart's Ease monograph — the full record covers uses, side effects and every documented interaction.

Read the full Heart's Ease monograph & all interactions
Medication

About Pindolol

What Is Pindolol Used For?

Brand names: Visken, Pindol

Pindolol tablets are approved to treat high blood pressure (hypertension). It can be used on its own or combined with other blood pressure medicines, particularly a thiazide-type diuretic (water pill).

Most-Reported Side Effects for Pindolol

From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Urinary tract infection 46 reports
Nausea 44 reports
Fatigue 43 reports
Dyspnea 42 reports
Dizziness 41 reports
See full Pindolol drug information
Keep checking

Other Drugs & Heart's Ease

Browse every other medication we’ve checked against Heart's Ease — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Heart's Ease References

The 4 references that drive our Heart's Ease monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Behmanesh Y, Abdollahi M. Hemolysis after consumption of Viola tricolor. WHO Drug Inf (Iran) 2002;16:15-16.
  3. Klovekorn, W., Tepe, A., and Danesch, U. A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatit
  4. Kirichenko TV, Sobenin IA, Markina YV, et al. Clinical effectiveness of a combination of black elder berries, violet herb, and calendula flowers in chronic obstructive pulmonary disease: the results of a double-blinded placebo-controlled study. Biology (B PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Heart's Ease and Pindolol Together: Common Questions

Is it safe to take Heart's Ease with Pindolol?
We do not list a known interaction between Heart's Ease and Pindolol. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Does Pindolol interact with any supplements?
Yes. Pindolol has documented interactions with 183 supplements in our database — Heart's Ease is not one of them. The Pindolol interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Pindolol and Heart's Ease?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.