Drug & supplement interaction

Lactobacillus Helveticus + Hydroxyzine

Hydroxyzine brand names: Atarax, Vistaril, Ucerax.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Lactobacillus Helveticus and Hydroxyzine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Lactobacillus Helveticus and Hydroxyzine

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Hydroxyzine and Lactobacillus Helveticus in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Lactobacillus Helveticus safety at a glance

Lactobacillus Helv... overall Use caution Generally well tolerated in healthy people, but people who are seriously ill or immunocompromised should be cautious.
Pregnancy Use caution Not enough reliable safety data; use only with your doctor's guidance.
Breastfeeding Use caution Limited safety information, so check with your doctor before use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Hydroxyzine and Lactobacillus Helveticus? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Hydroxyzine

Interactions in our licensed database are recorded against drug classes, not just single drug names. Hydroxyzine is filed under 5 classifications — including anticholinergic drugs, photosensitizing drugs, seizure threshold lowering drugs. Lactobacillus Helveticus has documented interactions with 1 drug class — the most serious being antibiotic drugs (moderate) — and none of Hydroxyzine’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Lactobacillus Helveticus Does Interact With Other Medications

Lactobacillus Helveticus has 182 moderate known drug interactions in our database — Hydroxyzine isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Lactobacillus Helveticus

Covers the 2,830 medications we’ve checked against Lactobacillus Helveticus. Pick one to open its full report.

What to actually watch for

What Lactobacillus Helveticus Itself Has Been Linked To

This is not an interaction — nothing below involves Hydroxyzine. It is the side-effect record for Lactobacillus Helveticus on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Lactobacillus Helveticus, this list is the first place to look. One entry is worth acting on rather than waiting out — marked below.

  • A higher chance of infection Worth acting on Additional detail

    “Since Lactobacillus helveticus preparations contain live and active microorganisms, there is some concern that they might cause pathogenic infection in some patients. Some lactobacilli species have been isolated in cases of bacteremia, sepsis, splenic abscess, endocarditis, necrotizing fasciitis, pancreatic necrosis, and meningoencephalitis.”

    Lactobacillus Helveticus · Natural Medicines adverse-effect record, reported in sepsis.

    1 source cited
    1. 107543. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Lactobacillus Helveticus — expand a row for the licensed statement it rests on. We read the ADVERSE REACTIONS section of Hydroxyzine’s FDA label too, and the two lists don’t meaningfully overlap — which is why no Hydroxyzine column appears here.

From our Q&A

Questions About Lactobacillus Helveticus or Hydroxyzine

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Lactobacillus Helveticus or Hydroxyzine, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Hydroxyzine

This page covers Lactobacillus Helveticus only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Hydroxyzine page lists 183 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Grapefruit (major), Henbane (major), Scopolia (major) and St. John's Wort (major).

By severity: 5 major · 135 moderate · 43 minor.

From our pharmacist’s overview on the Hydroxyzine page

“Hydroxyzine (Atarax, Vistaril) is a sedating antihistamine for itching and anxiety, so read this list closely before pairing it with any supplement. Five of the 183 ingredients on file rate major, and those come first: grapefruit and St.”

Reviewed by 2 · Jul 18, 2026

Open the Hydroxyzine interaction page

One more smart check

Taking Lactobacillus Helveticus as Part of a Dietary Supplement Product? Check It for Interactions

We hold 530 real supplement products containing Lactobacillus Helveticus, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lactobacillus Helveticus. Even though Lactobacillus Helveticus itself has no known interaction with Hydroxyzine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lactobacillus Helveticus and Hydroxyzine Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lactobacillus Helveticus
Top half

#381 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Hydroxyzine
Top 10%

#235 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Lactobacillus Helveticus reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Lactobacillus Helveticus and Hydroxyzine records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Lactobacillus Helveticus

What is Lactobacillus Helveticus?

  • Mood and stress support
  • Digestive and gut health
  • Sleep support
  • General immune support
  • Blood pressure support

Lactobacillus helveticus is a lactic acid bacterium used as a probiotic, often combined with other strains in mood, gut, and general wellness products. Early research is interesting—especially for stress and mood and for fermented-milk peptides and blood pressure—but evidence is still limited and not conclusive. It is generally well tolerated in healthy people, but talk to your pharmacist or doctor before using it, especially if you have a weakened immune system.

Lactobacillus helveticus · Lactobacillaceae · Live bacterial cultures (probiotic strain) · Capsules, tablets, powders, fermented dairy products (such as some cheeses and milk drinks); often combined with other probiotic strains

An interaction check asks whether these two react with each other — it does not ask whether Lactobacillus Helveticus is a good idea for someone in your situation. Here is what our Lactobacillus Helveticus record says about it on its own.

Lactobacillus Helveticus: dosing

There is no official standardized dose for L. helveticus. Probiotic products are usually measured in colony-forming units (CFU), and different products contain very different amounts and strain combinations.The best approach is to follow the directions on the product label and choose a reputable brand that lists the specific strain and CFU count.

From our Lactobacillus Helveticus monograph — the full record covers uses, side effects and every documented interaction.

Read the full Lactobacillus Helveticus monograph & all interactions
Medication

About Hydroxyzine

What Is Hydroxyzine Used For?

Brand names: Atarax, Vistaril, Ucerax

Hydroxyzine is used to relieve anxiety and tension related to psychoneurosis (anxiety-based mental health conditions) and as a supportive treatment when anxiety is part of another medical condition. Oral forms — including tablets, capsules, and oral solution — are used for anxiety relief and to manage itching (pruritus) caused by allergic conditions such as chronic urticaria (hives), atopic dermatitis, contact dermatitis, and histamine-driven itch. Oral forms are also used as a sedative before and after surgery or general anesthesia.

Hydroxyzine Hydrochloride intramuscular injection is used specifically when a shot is needed — for example, in acute psychiatric or emotional emergencies, acute alcohol withdrawal with anxiety symptoms or delirium tremens, control of nausea and vomiting (except during pregnancy), and as pre- and post-operative or pre- and post-partum supportive medication to reduce narcotic requirements and control nausea.

Most-Reported Side Effects for Hydroxyzine

From FAERS, the FDA’s public side-effect reporting system (50,845 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Pruritus 3,383 reports
Nausea 3,067 reports
Fatigue 2,961 reports
Toxicity to various agents 2,567 reports
Completed suicide 2,544 reports
See full Hydroxyzine drug information
Keep checking

Other Drugs & Lactobacillus Helveticus

Browse every other medication we’ve checked against Lactobacillus Helveticus — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
182Moderate
0Minor
2,647No known interaction
Moderate

182 interactions

Showing 60 of 182 moderate interactions — see all 182 on the Lactobacillus Helveticus page.

No interaction 2,647 drugs checked — show the list
Evidence & sources

Lactobacillus Helveticus References

The 2 references that drive our Lactobacillus Helveticus monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Lactobacillus Helveticus and Hydroxyzine Together: Common Questions

Is it safe to take Lactobacillus Helveticus with Hydroxyzine?
We do not list a known interaction between Lactobacillus Helveticus and Hydroxyzine. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Lactobacillus Helveticus and Hydroxyzine combination checked?
Interactions in our licensed database are recorded against drug classes. Hydroxyzine is filed under 5 classifications, and Lactobacillus Helveticus has documented interactions with 1 drug class — none of Hydroxyzine's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Lactobacillus Helveticus interact with any other medications?
Yes. Lactobacillus Helveticus has 182 documented drug interactions in our database — Hydroxyzine is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Hydroxyzine interact with any supplements?
Yes. Hydroxyzine has documented interactions with 183 supplements in our database — Lactobacillus Helveticus is not one of them. The Hydroxyzine interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Hydroxyzine and Lactobacillus Helveticus?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.