Drug & supplement interaction

Meadowsweet + Peginterferon alfa-2a, Ribavirin

Peginterferon alfa-2a, Ribavirin brand names: Pegasys, Pegetron.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Meadowsweet and Peginterferon alfa-2a, Ribavirin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Meadowsweet and Peginterferon alfa-2a, Ribavirin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Peginterferon alfa-2a, Ribavirin and Meadowsweet in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Meadowsweet safety at a glance

Meadowsweet overall Use caution Generally used in food-like amounts, but it contains salicylates and human safety data are limited.
Pregnancy Likely Unsafe When used orally. Some evidence suggests meadowsweet might stimulate uterine activity. Read the full pregnancy detail
Breastfeeding Avoid Not enough safety information; best avoided while breastfeeding.

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Peginterferon alfa-2a, Ribavirin and Meadowsweet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Peginterferon alfa-2a, Ribavirin

Interactions in our licensed database are recorded against drug classes, not just single drug names. Peginterferon alfa-2a, Ribavirin is filed under a single classification — oral drugs. Meadowsweet has documented interactions with 3 drug classes — the most serious being aspirin (moderate), choline magnesium trisalicylate (trilisate) (moderate) and salsalate (disalcid) (moderate) — and none of Peginterferon alfa-2a, Ribavirin’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Meadowsweet Does Interact With Other Medications

Meadowsweet has 39 moderate known drug interactions in our database — Peginterferon alfa-2a, Ribavirin isn’t one of them. If you take anything else, check it against the full list below.

Moderate 39 No known interaction 2,791 (incl. Peginterferon alfa-2a, Ribavirin)
Taking anything else?

Check Another of Your Medications Against Meadowsweet

Covers the 2,830 medications we’ve checked against Meadowsweet. Pick one to open its full report.

What to actually watch for

No Interaction Found — But Data Suggests Meadowsweet and Peginterferon alfa-2a, Ribavirin May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Stomach upset / Vomiting / Nausea Additional detail

    Meadowsweet

    “Orally, large doses of meadowsweet can cause nausea and other stomach complaints (18).

    Meadowsweet contains salicylate constituents. There is insufficient reliable information available to know if the side effects and toxicity normally associated with salicylates could occur with meadowsweet use. Adverse reactions associated with salicylates include gastric irritation, hematochezia, nausea, and vomiting (4).”

    Meadowsweet · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    2 sources cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
    2. 4. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

    Peginterferon alfa-2a, Ribavirin

    Listed in the ADVERSE REACTIONS section of the FDA label for Peginterferon alfa-2a, Ribavirin. Read the label on DailyMed ›

Reported for Meadowsweet but not commonly for Peginterferon alfa-2a, Ribavirin: ringing in the ears.

Effects for Peginterferon alfa-2a, Ribavirin come from the ADVERSE REACTIONS section of its FDA label; effects for Meadowsweet come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Meadowsweet in Pregnancy & Breastfeeding

Pregnancy Likely Unsafe

When used orally. Some evidence suggests meadowsweet might stimulate uterine activity.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Peginterferon alfa-2a, Ribavirin

This page covers Meadowsweet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Peginterferon alfa-2a, Ribavirin page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Peginterferon alfa-2a, Ribavirin page

“Hepatitis C treatment with Pegasys or Pegetron (peginterferon alfa-2a plus ribavirin) is rough on the stomach, and the charcoal, fiber powders, and soothing gums people reach for are exactly what fills this list. All 17 entries work the same way, interfering with how the oral ribavirin half of the therapy gets absorbed.”

Reviewed by 2 · Jul 18, 2026

Open the Peginterferon alfa-2a, Ribavirin interaction page

One more smart check

Taking Meadowsweet as Part of a Dietary Supplement Product? Check It for Interactions

We hold 197 real supplement products containing Meadowsweet, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Meadowsweet. Even though Meadowsweet itself has no known interaction with Peginterferon alfa-2a, Ribavirin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Meadowsweet and Peginterferon alfa-2a, Ribavirin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Meadowsweet
Top half

#436 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Peginterferon alfa-2a, Ribavirin
Top 5%

#74 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Meadowsweet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Meadowsweet and Peginterferon alfa-2a, Ribavirin records this page draws on were last updated July 11, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Meadowsweet

What is Meadowsweet?

Meadowsweet
  • Heartburn and indigestion
  • Cold and flu symptoms
  • Mild aches and pains
  • Fever
  • Joint discomfort

Meadowsweet is a traditional European herb that contains natural salicylates (aspirin-like compounds) and is used mainly for digestive upset, colds, and minor aches. High-quality human studies are lacking, so its benefits are not well proven, and people sensitive to aspirin should be cautious. Talk with your pharmacist or doctor before using it.

Filipendula ulmaria · Rosaceae · Flowers and above-ground (aerial) parts, sometimes the root · Tea, dried herb, tincture, liquid extract, capsules

An interaction check asks whether these two react with each other — it does not ask whether Meadowsweet is a good idea for someone in your situation. Here is what our Meadowsweet record says about it on its own.

Meadowsweet: dosing

There is no well-established, standardized dose for meadowsweet. Traditional use varies widely depending on the form — for example, dried flowers steeped as a tea, or a tincture or capsule taken according to the maker's directions.Because product strengths differ a great deal, the safest approach is to follow the directions on the product label and not exceed the recommended amount.

From our Meadowsweet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Meadowsweet monograph & all interactions
Medication

About Peginterferon Alfa-2a Injection

What Is Peginterferon Alfa-2a Injection Used For?

Brand names: Pegasys, Pegetron

Pegasys (peginterferon alfa-2a) is used to treat chronic hepatitis C (CHC) and chronic hepatitis B (CHB). For chronic hepatitis C in adults, Pegasys is typically used in combination with other hepatitis C antiviral drugs; it may be used alone only if other HCV drugs cannot be tolerated or are contraindicated. For children aged 5 and older with CHC, Pegasys is used in combination with ribavirin.

For chronic hepatitis B, Pegasys treats adults who have HBeAg-positive or HBeAg-negative CHB with compensated liver disease and evidence of active viral replication and liver inflammation. In children aged 3 and older with HBeAg-positive CHB (without cirrhosis), Pegasys is also indicated when there is evidence of viral replication and liver enzyme elevation.

See full Peginterferon Alfa-2a Injection drug information
Keep checking

Other Drugs & Meadowsweet

Browse every other medication we’ve checked against Meadowsweet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
39Moderate
0Minor
2,790No known interaction
39 Moderate 2,790 No interaction
Moderate

39 interactions

No interaction 2,790 drugs checked — show the list

We also checked Meadowsweet against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,790 medications checked with no known interaction — see the full Meadowsweet list.

See the full Meadowsweet interactions page
See every supplement checked against Peginterferon alfa-2a, Ribavirin, ranked by severity
Evidence & sources

Meadowsweet References

The 3 references that drive our Meadowsweet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Meadowsweet and Peginterferon alfa-2a, Ribavirin Together: Common Questions

Is it safe to take Meadowsweet with Peginterferon alfa-2a, Ribavirin?
We do not list a known interaction between Meadowsweet and Peginterferon alfa-2a, Ribavirin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Meadowsweet and Peginterferon alfa-2a, Ribavirin have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
How was the Meadowsweet and Peginterferon alfa-2a, Ribavirin combination checked?
Interactions in our licensed database are recorded against drug classes. Peginterferon alfa-2a, Ribavirin is filed under 1 classification, and Meadowsweet has documented interactions with 3 drug classes — none of Peginterferon alfa-2a, Ribavirin's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Meadowsweet interact with any other medications?
Yes. Meadowsweet has 39 documented drug interactions in our database — Peginterferon alfa-2a, Ribavirin is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Peginterferon alfa-2a, Ribavirin interact with any supplements?
Yes. Peginterferon alfa-2a, Ribavirin has documented interactions with 17 supplements in our database — Meadowsweet is not one of them. The Peginterferon alfa-2a, Ribavirin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Meadowsweet monograph Uses, safety profile, and every drug interaction in one place Peginterferon Alfa-2a Injection drug information The full plain-English guide to this medication Peginterferon alfa-2a, Ribavirin supplement interactions Every supplement checked against Peginterferon alfa-2a, Ribavirin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 3 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Peginterferon alfa-2a, Ribavirin and Meadowsweet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.